FI792995A7 - Framstaellning av kefalosporiner - Google Patents

Framstaellning av kefalosporiner

Info

Publication number
FI792995A7
FI792995A7 FI792995A FI792995A FI792995A7 FI 792995 A7 FI792995 A7 FI 792995A7 FI 792995 A FI792995 A FI 792995A FI 792995 A FI792995 A FI 792995A FI 792995 A7 FI792995 A7 FI 792995A7
Authority
FI
Finland
Prior art keywords
kephalosporiner
framstaellning
Prior art date
Application number
FI792995A
Other languages
English (en)
Other versions
FI74709C (fi
FI74709B (fi
Inventor
Derek Walker
Herbert H Silvestri
Chester Sapino
David A Johnson
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI792995A7 publication Critical patent/FI792995A7/fi
Application granted granted Critical
Publication of FI74709B publication Critical patent/FI74709B/fi
Publication of FI74709C publication Critical patent/FI74709C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06—Acylation of 7-aminocephalosporanic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
FI792995A 1979-03-19 1979-09-26 Trimetylsilyloxikarbonyl-7- aminodecefalosporansyra-trimetylsilylester foer anvaendning som mellanprodukt och foerfarande foer framstaellning av denna. FI74709C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2151179 1979-03-19
US06/021,511 US4223135A (en) 1979-03-19 1979-03-19 Production of cephalosporins

Publications (3)

Publication Number Publication Date
FI792995A7 true FI792995A7 (fi) 1980-09-20
FI74709B FI74709B (fi) 1987-11-30
FI74709C FI74709C (fi) 1988-03-10

Family

ID=21804643

Family Applications (1)

Application Number Title Priority Date Filing Date
FI792995A FI74709C (fi) 1979-03-19 1979-09-26 Trimetylsilyloxikarbonyl-7- aminodecefalosporansyra-trimetylsilylester foer anvaendning som mellanprodukt och foerfarande foer framstaellning av denna.

Country Status (21)

Country Link
US (1) US4223135A (fi)
JP (2) JPS55129290A (fi)
AR (1) AR231143A1 (fi)
CA (1) CA1130278A (fi)
CH (1) CH642969A5 (fi)
DE (1) DE2951477A1 (fi)
DK (2) DK161522C (fi)
ES (2) ES486463A0 (fi)
FI (1) FI74709C (fi)
FR (1) FR2467213A1 (fi)
GB (1) GB2044248B (fi)
GR (1) GR82675B (fi)
HU (2) HU180687B (fi)
IE (1) IE49212B1 (fi)
IL (1) IL58396A (fi)
IT (1) IT1164907B (fi)
NL (1) NL7907551A (fi)
NO (1) NO158137C (fi)
PH (1) PH15449A (fi)
SE (2) SE445554B (fi)
ZA (1) ZA795132B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2069482B (en) * 1980-02-14 1984-04-04 Gist Brocades Nv Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives
AT381315B (de) * 1984-11-23 1986-09-25 Biochemie Gmbh Verfahren zur herstellung von cephalosporinderivaten
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
US5142043A (en) * 1990-05-10 1992-08-25 Biocraft Laboratories, Inc. Process for preparing cephalexin monohydrate
US20070111980A1 (en) * 2004-07-16 2007-05-17 Bandi Parthasaradhi Reddy Process for preparing pure cephalosporine intermediates
US7207857B2 (en) * 2005-09-20 2007-04-24 Patent Category Corp. Floating assemblies
CN101448842A (zh) * 2006-05-19 2009-06-03 帝斯曼知识产权资产管理有限公司 一种用于结晶头孢羟氨苄的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE311519B (fi) 1962-12-14 1969-06-16 Astra Ab
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
US3819623A (en) * 1968-04-12 1974-06-25 Fujisawa Pharmaceutical Co 3,7-disubstituted cephalosporin compounds
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
GB1332306A (en) * 1969-12-23 1973-10-03 Glaxo Lab Ltd Antibiotics
US3671449A (en) * 1970-08-19 1972-06-20 Lilly Co Eli Cephalosporin compositions
US3694437A (en) * 1970-08-19 1972-09-26 Lilly Co Eli Process for preparing cephalosporin compounds
US3867380A (en) * 1971-02-18 1975-02-18 Smithkline Corp 3-Heterocyclic thiomethylcephalosporins
US3828037A (en) * 1972-07-20 1974-08-06 Smithkline Corp Trifluoromethylmercaptoacetamidocephalosporins
US3965098A (en) * 1972-11-29 1976-06-22 American Home Products Corporation Intermediates for preparing cephalosporins and methods of production
US4051131A (en) * 1972-11-29 1977-09-27 American Home Products Corporation (Del.) Intermediates for preparing cephalosporins
US3928336A (en) * 1974-07-29 1975-12-23 Bristol Myers Co 7-{8 D-({60 -amino{60 -phenyl-, 2-thienyl- and 3-thienyl-acetamido){9 -3-(3-methyl-1,2,5-oxadiazol-4-yl)carbonylthiomethyl-3-cephem-4-carboxylic acids
JPS525787A (en) * 1975-06-27 1977-01-17 Bristol Myers Co Antiibacterial agent

Also Published As

Publication number Publication date
FR2467213A1 (fr) 1981-04-17
GR82675B (fi) 1985-02-07
HU180687B (en) 1983-04-29
DE2951477C2 (fi) 1987-07-23
ES8102577A1 (es) 1981-01-16
US4223135A (en) 1980-09-16
IL58396A (en) 1983-06-15
IT7950520A0 (it) 1979-10-10
IE792211L (en) 1980-09-19
AR231143A1 (es) 1984-09-28
CH642969A5 (de) 1984-05-15
SE458608B (sv) 1989-04-17
NO158137B (no) 1988-04-11
JPH0351715B2 (fi) 1991-08-07
JPS55129290A (en) 1980-10-06
HU188767B (en) 1986-05-28
FR2467213B1 (fi) 1984-01-06
GB2044248B (en) 1983-04-20
DK164365B (da) 1992-06-15
DE2951477A1 (de) 1980-10-09
DK164365C (da) 1992-11-16
SE8404730L (sv) 1984-09-20
JPH0214358B2 (fi) 1990-04-06
DK8891D0 (da) 1991-01-18
DK161522B (da) 1991-07-15
ES486463A0 (es) 1981-01-16
PH15449A (en) 1983-01-18
IE49212B1 (en) 1985-08-21
FI74709C (fi) 1988-03-10
CA1130278A (en) 1982-08-24
IL58396A0 (en) 1980-01-31
ZA795132B (en) 1981-06-24
SE7907902L (sv) 1980-09-20
DK161522C (da) 1991-12-23
SE445554B (sv) 1986-06-30
GB2044248A (en) 1980-10-15
ES492956A0 (es) 1981-06-01
ES8105327A1 (es) 1981-06-01
SE8404730D0 (sv) 1984-09-20
JPS62161789A (ja) 1987-07-17
NL7907551A (nl) 1980-09-23
DK406579A (da) 1981-03-28
FI74709B (fi) 1987-11-30
NO793103L (no) 1980-09-22
IT1164907B (it) 1987-04-15
NO158137C (no) 1988-07-20
DK8891A (da) 1991-01-18

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BRISTOL-MYERS CO