FI873512L - Homogena rekombinant-immuninterferonfragment. - Google Patents

Homogena rekombinant-immuninterferonfragment. Download PDF

Info

Publication number
FI873512L
FI873512L FI873512A FI873512A FI873512L FI 873512 L FI873512 L FI 873512L FI 873512 A FI873512 A FI 873512A FI 873512 A FI873512 A FI 873512A FI 873512 L FI873512 L FI 873512L
Authority
FI
Finland
Prior art keywords
immune interferon
recombinant immune
interferon fragment
homogenous recombinant
homogenous
Prior art date
Application number
FI873512A
Other languages
English (en)
Finnish (fi)
Other versions
FI873512A7 (fi
FI873512A0 (fi
Inventor
Heinz Doebeli
Reiner Gentz
Erich Hochuli
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI873512A0 publication Critical patent/FI873512A0/fi
Publication of FI873512A7 publication Critical patent/FI873512A7/fi
Publication of FI873512L publication Critical patent/FI873512L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/57IFN-gamma
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI873512A 1986-08-13 1987-08-13 Homogena rekombinant-immuninterferonfragment. FI873512L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868619725A GB8619725D0 (en) 1986-08-13 1986-08-13 Homogenous interferon fragments

Publications (3)

Publication Number Publication Date
FI873512A0 FI873512A0 (fi) 1987-08-13
FI873512A7 FI873512A7 (fi) 1988-02-14
FI873512L true FI873512L (fi) 1988-02-14

Family

ID=10602667

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873512A FI873512L (fi) 1986-08-13 1987-08-13 Homogena rekombinant-immuninterferonfragment.

Country Status (21)

Country Link
EP (1) EP0256424B1 (da)
JP (1) JPS6349098A (da)
KR (1) KR880002996A (da)
AR (1) AR244808A1 (da)
AT (1) ATE67783T1 (da)
AU (1) AU607930B2 (da)
DE (1) DE3773295D1 (da)
DK (1) DK377787A (da)
ES (1) ES2051714T3 (da)
FI (1) FI873512L (da)
GB (1) GB8619725D0 (da)
GR (1) GR3003417T3 (da)
HU (1) HU202920B (da)
IE (1) IE60670B1 (da)
IL (1) IL83474A0 (da)
MC (1) MC1847A1 (da)
NO (1) NO174631C (da)
NZ (1) NZ221374A (da)
PH (1) PH27432A (da)
PT (1) PT85538B (da)
ZA (1) ZA875819B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2969461B2 (ja) * 1988-07-23 1999-11-02 株式会社林原生物化学研究所 ヒトγ−インターフェロンとその製造方法並びに用途
DE3730331A1 (de) * 1987-09-10 1989-03-30 Basf Ag Neue polypeptide, verfahren zur herstellung, die vektoren dafuer und arzneimittel daraus
ATE112686T1 (de) * 1990-08-31 1994-10-15 Schering Corp Verwendungsmethoden von humanem gammainterferon 4-134.
DE4036856C1 (da) * 1990-11-19 1992-05-27 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
SK8292002A3 (en) 1999-11-12 2002-12-03 Maxygen Holdings Ltd A conjugate exhibiting interferon gamma activity, nucleotide sequence encoding for a polypeptide fraction of conjugate, an expression vector and a host cell containing nucleotide sequence, pharmaceutical composition comprising the same and use thereof
US7230081B1 (en) 1999-11-12 2007-06-12 Maxygen Holdings, Ltd. Interferon gamma conjugates
US7959910B2 (en) 2000-07-31 2011-06-14 Biolex Therapeutics, Inc. C-terminally truncated interferon alpha variants
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
WO2004005341A2 (en) 2002-07-03 2004-01-15 Maxygen Holdings Ltd. Full-length interferon gamma polypeptide variants
US20060024272A1 (en) * 2004-07-29 2006-02-02 Large Scale Biology Corporation C-terminally truncated interferon

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0788398B2 (ja) * 1983-10-17 1995-09-27 サントリー株式会社 新規生理活性ポリペプチドおよびその製造法
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
JPS60172999A (ja) * 1983-12-20 1985-09-06 Suntory Ltd 新規な塩基性ポリペプチドおよびその製造法
US4758656A (en) * 1983-12-26 1988-07-19 Kyowa Hakko Kogyo Co., Ltd. Novel human interferon-gamma polypeptide derivative
DE3414831A1 (de) * 1984-04-19 1985-10-31 Hoechst Ag, 6230 Frankfurt Herstellung von polypeptiden mit human-gammainterferon-aktivitaet
IL75302A0 (en) * 1984-06-06 1985-09-29 Takeda Chemical Industries Ltd Novel polypeptide and production thereof
WO1985005618A1 (fr) * 1984-06-06 1985-12-19 Takeda Chemical Industries, Ltd. Procede de preparation de derives de l'interferon
JPS6124599A (ja) * 1984-07-11 1986-02-03 Kyowa Hakko Kogyo Co Ltd 新規ヒトインタ−フエロン−rポリペプチド誘導体
JPS6163696A (ja) * 1984-09-05 1986-04-01 Asahi Chem Ind Co Ltd 新しいペプチド
JPS61108397A (ja) * 1984-10-31 1986-05-27 Green Cross Corp:The インタ−フエロン−γ蛋白質の製造法
JPS62289600A (ja) * 1986-02-18 1987-12-16 Kanegafuchi Chem Ind Co Ltd インタ−フエロン−γ及びその製造方法

Also Published As

Publication number Publication date
ZA875819B (en) 1988-02-15
NO174631C (no) 1994-06-08
PH27432A (en) 1993-06-21
EP0256424A1 (en) 1988-02-24
FI873512A7 (fi) 1988-02-14
AU7668687A (en) 1988-05-19
IE872160L (en) 1988-02-13
NO174631B (no) 1994-02-28
HU202920B (en) 1991-04-29
PT85538A (en) 1987-09-01
NO873389D0 (no) 1987-08-12
KR880002996A (ko) 1988-05-13
DK377787D0 (da) 1987-07-20
IL83474A0 (en) 1988-01-31
DK377787A (da) 1988-02-14
IE60670B1 (en) 1994-08-10
GR3003417T3 (en) 1993-02-17
DE3773295D1 (de) 1991-10-31
EP0256424B1 (en) 1991-09-25
JPS6349098A (ja) 1988-03-01
PT85538B (pt) 1990-06-29
MC1847A1 (fr) 1988-09-30
HUT47148A (en) 1989-01-30
NO873389L (no) 1988-02-15
AR244808A1 (es) 1993-11-30
FI873512A0 (fi) 1987-08-13
NZ221374A (en) 1990-07-26
ATE67783T1 (de) 1991-10-15
GB8619725D0 (en) 1986-09-24
AU607930B2 (en) 1991-03-21
ES2051714T3 (es) 1994-07-01

Similar Documents

Publication Publication Date Title
DE10399031I1 (de) Rekombinante Viren.
DK603888D0 (da) Rekombinant virus
DE3786767D1 (de) Neues polypeptid.
FI892136L (fi) Rekombinant antikropp.
FI874819L (fi) Human rekombinant endotelcell vaextfaktor.
FI892714A0 (fi) Rekombinant-coccidiosisvaccin.
NO852173L (no) Rekombinant lymfotoksin.
ATA257190A (de) Virales polypeptid
FI874287A7 (fi) Uudet lymfokiinipeptidit.
DE3683186D1 (de) Rekombinantes humaninterleukin-1.
DE3850019D1 (de) Rekombinantes Avipoxvirus.
FI870457L (fi) Farmaceutiska preparatformer foer stabilisering av interferon.
DE3788408D1 (de) Immunverstärkung.
DK551287D0 (da) Polypeptid
NO873389D0 (no) Homogent rekombinant immun-interferon-fragment.
FI885296L (fi) Rekombinant hiv-2 polypeptid.
DE59002183D1 (de) Stabilisierte leukocyten-interferone.
DE3853743D1 (de) Rekombinanter menschlicher ADF.
FI852866A0 (fi) Rekombinantfaktor viii-r.
FI895456A0 (fi) Rekombinant interleukin 2-hybridproteiner.
NO890174D0 (no) Rekombinante interleukin-1alfa-polypeptider.
ATA264487A (de) Homogene, rekombinante immun-interferonfragmente
FI864626L (fi) Rekombinantricintoxin.
FI882741L (fi) Rekombinant htlv-iii-proteiner och deras anvaendning.
EP0244427A4 (en) RECOMBINANT VIRUS.

Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG