FI913702L - (2r)-2-/di(2-propyl)fosfonylmetoxi/-3 -p-toluensulfonyloxi-1-trimetylacetoxipropan, dess framstaellning och anvaendning. - Google Patents

(2r)-2-/di(2-propyl)fosfonylmetoxi/-3 -p-toluensulfonyloxi-1-trimetylacetoxipropan, dess framstaellning och anvaendning. Download PDF

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Publication number
FI913702L
FI913702L FI913702A FI913702A FI913702L FI 913702 L FI913702 L FI 913702L FI 913702 A FI913702 A FI 913702A FI 913702 A FI913702 A FI 913702A FI 913702 L FI913702 L FI 913702L
Authority
FI
Finland
Prior art keywords
trimethylacetoxipropan
toluensulfonyloxi
phosphonylmethoxi
propyl
framstaellning och
Prior art date
Application number
FI913702A
Other languages
English (en)
Finnish (fi)
Other versions
FI913702A7 (fi
FI913702A0 (fi
Inventor
Petr Alexander
Antonin Holy
Hana Dvorakova
Original Assignee
Ceskoslovenska Akademie Ved
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceskoslovenska Akademie Ved filed Critical Ceskoslovenska Akademie Ved
Publication of FI913702A0 publication Critical patent/FI913702A0/fi
Publication of FI913702A7 publication Critical patent/FI913702A7/fi
Publication of FI913702L publication Critical patent/FI913702L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI913702A 1990-08-06 1991-08-02 (2r)-2-/di(2-propyl)fosfonylmetoxi/-3 -p-toluensulfonyloxi-1-trimetylacetoxipropan, dess framstaellning och anvaendning. FI913702L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS903871A CS276072B6 (en) 1990-08-06 1990-08-06 (2R)-2-/DI(2-PROPYL)PHOSPHONYLMETHOXY/-3-p-TOLUENESULFONYLOXY -1- TRIMETHYLACETOXYPROPANE AND PROCESS FOR PREPARING THEREOF

Publications (3)

Publication Number Publication Date
FI913702A0 FI913702A0 (fi) 1991-08-02
FI913702A7 FI913702A7 (fi) 1992-02-07
FI913702L true FI913702L (fi) 1992-02-07

Family

ID=5380072

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913702A FI913702L (fi) 1990-08-06 1991-08-02 (2r)-2-/di(2-propyl)fosfonylmetoxi/-3 -p-toluensulfonyloxi-1-trimetylacetoxipropan, dess framstaellning och anvaendning.

Country Status (13)

Country Link
US (2) US5130427A (cs)
EP (1) EP0470809A1 (cs)
JP (1) JP2955402B2 (cs)
AU (1) AU8149291A (cs)
CA (1) CA2046755C (cs)
CS (1) CS276072B6 (cs)
FI (1) FI913702L (cs)
IE (1) IE71217B1 (cs)
IL (1) IL98849A0 (cs)
NO (1) NO913035L (cs)
NZ (1) NZ239131A (cs)
PT (1) PT98590B (cs)
ZA (1) ZA915932B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ284678B6 (cs) * 1991-05-20 1999-01-13 Ústav Organické Chemie A Biochemie Avčr Di(2-propyl)estery 1-fluor-2-fosfonomethoxy-3-p -toluensulfonyloxypropanů, způsob jejich přípravy a použití
US6057305A (en) 1992-08-05 2000-05-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiretroviral enantiomeric nucleotide analogs
JP2532818B2 (ja) 1993-02-01 1996-09-11 松下電器産業株式会社 対物レンズおよび光ヘッド装置
US5502177A (en) * 1993-09-17 1996-03-26 Gilead Sciences, Inc. Pyrimidine derivatives for labeled binding partners
AU3851601A (en) * 2000-02-18 2001-08-27 Southern Res Inst Methods for synthesizing 2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-9h- purin-6-amine
HRP20030047B1 (hr) 2000-07-21 2016-02-26 Gilead Sciences, Inc. Prolijekovi koji su fosfonatni analozi nukleotida i metode njihovog odabira te njihova priprava
AU2003235501A1 (en) * 2002-05-13 2003-11-11 Metabasis Therapeutics, Inc. PMEA and PMPA cyclic producing synthesis
IL164809A0 (en) * 2002-05-13 2005-12-18 Metabasis Therapeutics Inc Novel phosphonic acid basdrugs of pmea and its analogues
MXPA06014013A (es) * 2004-06-08 2007-03-15 Metabasis Therapeutics Inc Sintesis mediada por acidos de lewis de esteres ciclicos.
WO2012079035A1 (en) 2010-12-10 2012-06-14 Sigmapharm Laboratories, Llc Highly stable compositions of orally active nucleotide analogues or orally active nucleotide analogue prodrugs
CA2857490C (en) 2011-12-22 2020-03-31 Geron Corporation Guanine analogs as telomerase substrates and telomere length affectors
EP3623364A1 (en) 2014-02-13 2020-03-18 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
CN106687118A (zh) 2014-07-02 2017-05-17 配体药物公司 前药化合物及其用途
WO2019139919A1 (en) 2018-01-09 2019-07-18 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof
JP7151348B2 (ja) * 2018-10-03 2022-10-12 日本製鉄株式会社 金属板用塗料およびこれを用いた塗装金属板の製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868187A (en) * 1980-09-16 1989-09-19 Syntex (U.S.A.) Inc. Anti-viral N-substituted pyrimidines
US4816447A (en) * 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
CS233665B1 (en) * 1983-01-06 1985-03-14 Antonin Holy Processing of isomere o-phosphonylmethylderivative of anantiomere racemic vicinal diene
US5047533A (en) * 1983-05-24 1991-09-10 Sri International Acyclic purine phosphonate nucleotide analogs
CS263951B1 (en) * 1985-04-25 1989-05-12 Antonin Holy 9-(phosponylmethoxyalkyl)adenines and method of their preparation
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
AU8092587A (en) * 1986-11-18 1988-05-19 Bristol-Myers Squibb Company Synthesis of purin-9-ylalkylenoxymethyl phosphonic acids
US4927830A (en) * 1988-04-08 1990-05-22 The Regents Of The University Of Michigan Acyclic pyrrolo[2,3-D]pyrimidine analogs as antiviral agents
US4968686A (en) * 1988-04-08 1990-11-06 The Regents Of The University Of Michigan Acyclic pyrrolo [2,3-d]pyrimidine analogs as antiviral agents
CA2088363C (en) * 1990-08-10 2002-05-28 Purushotham Vemishetti Process for the preparation of nucleotides

Also Published As

Publication number Publication date
PT98590A (pt) 1992-06-30
US5130427A (en) 1992-07-14
JP2955402B2 (ja) 1999-10-04
IE912758A1 (en) 1992-02-12
CS387190A3 (en) 1992-03-18
FI913702A7 (fi) 1992-02-07
CS276072B6 (en) 1992-03-18
AU8149291A (en) 1992-02-13
NO913035D0 (no) 1991-08-05
PT98590B (pt) 1999-04-30
CA2046755C (en) 2002-02-12
IL98849A0 (en) 1992-07-15
USRE35558E (en) 1997-07-08
JPH05230087A (ja) 1993-09-07
EP0470809A1 (en) 1992-02-12
NZ239131A (en) 1994-04-27
FI913702A0 (fi) 1991-08-02
ZA915932B (en) 1992-04-29
IE71217B1 (en) 1997-02-12
NO913035L (no) 1992-02-07
CA2046755A1 (en) 1992-02-07

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