FI934426L - Tiazolidindionderivat, framstaellning och anvaendning daerav - Google Patents

Tiazolidindionderivat, framstaellning och anvaendning daerav Download PDF

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Publication number
FI934426L
FI934426L FI934426A FI934426A FI934426L FI 934426 L FI934426 L FI 934426L FI 934426 A FI934426 A FI 934426A FI 934426 A FI934426 A FI 934426A FI 934426 L FI934426 L FI 934426L
Authority
FI
Finland
Prior art keywords
dionderivat
thiazolidin
framstaellning och
och anvaendning
daerav
Prior art date
Application number
FI934426A
Other languages
English (en)
Finnish (fi)
Other versions
FI934426A0 (fi
FI934426A7 (fi
Inventor
Takashi Sohda
Hitoshi Ikeda
John C Greenfield
Jerry R Colca
Edgar N Petzold
Original Assignee
Upjohn Co
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13672917&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI934426(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co, Takeda Chemical Industries Ltd filed Critical Upjohn Co
Publication of FI934426A0 publication Critical patent/FI934426A0/fi
Publication of FI934426A7 publication Critical patent/FI934426A7/fi
Publication of FI934426L publication Critical patent/FI934426L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Graft Or Block Polymers (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI934426A 1991-04-11 1992-04-06 Tiazolidindionderivat, framstaellning och anvaendning daerav FI934426L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7883691 1991-04-11
PCT/US1992/002566 WO1992018501A1 (en) 1991-04-11 1992-04-06 Thiazolidinedione derivatives, production and use thereof

Publications (3)

Publication Number Publication Date
FI934426A0 FI934426A0 (fi) 1993-10-08
FI934426A7 FI934426A7 (fi) 1993-10-08
FI934426L true FI934426L (fi) 1993-10-08

Family

ID=13672917

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934426A FI934426L (fi) 1991-04-11 1992-04-06 Tiazolidindionderivat, framstaellning och anvaendning daerav

Country Status (19)

Country Link
EP (1) EP0579733B1 (cs)
JP (1) JP3176694B2 (cs)
KR (1) KR100249988B1 (cs)
AT (1) ATE202352T1 (cs)
AU (1) AU1743292A (cs)
CA (1) CA2106967C (cs)
CZ (1) CZ196693A3 (cs)
DE (1) DE69231886T2 (cs)
DK (1) DK0579733T3 (cs)
ES (1) ES2161692T3 (cs)
FI (1) FI934426L (cs)
GR (1) GR3036623T3 (cs)
HU (1) HUT68370A (cs)
MX (1) MX9201637A (cs)
NO (1) NO933615L (cs)
PT (1) PT100366A (cs)
SK (1) SK109993A3 (cs)
TW (1) TW209864B (cs)
WO (1) WO1992018501A1 (cs)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022445A1 (en) * 1992-05-05 1993-11-11 The Upjohn Company A process for producing pioglitazone metabolite
TW268952B (cs) * 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
NO305987B1 (no) * 1994-04-11 1999-08-30 Sankyo Co Heterosykliske forbindelser med antidiabetisk aktivitet, deres anvendelse og farmasoeytisk preparat inneholdende disse
TW438587B (en) * 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
EP1671637A3 (en) 1997-06-18 2007-12-19 SmithKline Beecham P.L.C. Treatment of diabetes with thiazolidinedione and sulphonylurea
WO2000028989A1 (en) * 1998-11-12 2000-05-25 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
DZ2937A1 (fr) 1998-11-12 2004-03-15 Smithkline Beecham Plc Compositions nouvelles de sensibilidants à l'insuline.
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
DE20119200U1 (de) 2001-11-27 2003-04-10 Joh. Winklhofer & Söhne GmbH und Co KG, 81369 München Kettenspanner mit mechanischer Verriegelung
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
KR100646128B1 (ko) 2005-04-21 2006-11-14 전라옥 ＰＰＡＲγ에 선택적으로 작용하는 테트라하이드로퀴놀린계열 티아졸리딘디온 유도체 및 그 합성방법
AU2013200104B2 (en) * 2006-03-16 2014-05-15 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
EP2902026B1 (en) * 2006-03-16 2017-10-04 Metabolic Solutions Development Company LLC Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
CA2646170A1 (en) * 2006-03-16 2007-09-27 Metabolic Solutions Development Company Combination therapies of thiazolidinedione analogues and glucocorticoid agonists
CN101454006B (zh) * 2006-03-16 2012-12-26 新陈代谢解决方案开发公司 用于治疗高血压以及用于降低血脂的噻唑烷二酮类似物
US7435741B2 (en) 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
WO2008038359A1 (en) 2006-09-28 2008-04-03 Daido Kogyo Co., Ltd. Chain tensioner
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
CN101848901B (zh) 2007-09-14 2012-11-21 新陈代谢解决方案开发公司 用于治疗高血压的噻唑烷二酮类似物
US8722710B2 (en) 2007-09-26 2014-05-13 Deuterx, Llc Deuterium-enriched pioglitazone
US8912335B2 (en) 2009-12-15 2014-12-16 Metabolic Solutions Development Company, Llc PPAR-sparing thiazolidinedione salts for the treatment of metabolic diseases
CN103153972A (zh) * 2010-04-19 2013-06-12 新陈代谢解决方案开发公司 噻唑烷二酮化合物的新的合成方法
PL2560956T3 (pl) * 2010-04-19 2017-03-31 Octeta Therapeutics, Llc Nowa synteza związków tiazolidynodionowych
KR101857307B1 (ko) * 2010-08-10 2018-05-11 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 티아졸리딘디온 화합물의 합성법
CA2807662C (en) 2010-08-10 2019-10-08 Metabolic Solutions Development Company, Llc Synthesis for thiazolidinedione compounds
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
CA2941562C (en) * 2013-03-14 2021-09-21 Deuterx, Llc Deuterium-enriched 2,4-thiazolidinediones and methods of treatment
ES2831326T3 (es) 2014-01-15 2021-06-08 Poxel Sa Métodos para tratar trastornos neurológicos, metabólicos y otros mediante el uso de pioglitazona enantiopura enriquecida con deuterio
NZ725492A (en) 2014-04-02 2023-06-30 Minoryx Therapeutics S L 2,4-thiazolidinedione derivatives in the treatment of central nervous system disorders
WO2016071727A1 (en) 2014-11-04 2016-05-12 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
MX379710B (es) * 2016-12-01 2025-03-11 Minoryx Therapeutics S L 5-[[4-[2-[5-(1-hidroxietil)piridin-2-il]etoxi]fenil]metil]]-1,3-tiazolidin-2,4-diona para el tratamiento de enfermedad de higado graso no alcoholico.
CN110198945B (zh) 2016-12-23 2023-06-27 米尼奥尔克斯治疗有限公司 用于制备噻唑烷二酮化合物及其盐的方法
US11767317B1 (en) 2020-06-30 2023-09-26 Poxel Sa Methods of synthesizing enantiopure deuterium-enriched pioglitazone
US11319313B2 (en) 2020-06-30 2022-05-03 Poxel Sa Crystalline forms of deuterium-enriched pioglitazone
WO2024231881A2 (en) * 2023-05-09 2024-11-14 Minoryx Therapeutics S.L. Polymorphic forms and formulations of leriglitazone

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales

Also Published As

Publication number Publication date
CZ196693A3 (en) 1994-05-18
PT100366A (pt) 1993-06-30
DK0579733T3 (da) 2001-10-15
WO1992018501A1 (en) 1992-10-29
NO933615D0 (no) 1993-10-08
SK109993A3 (en) 1994-12-07
FI934426A0 (fi) 1993-10-08
CA2106967A1 (en) 1992-10-12
DE69231886T2 (de) 2002-03-28
FI934426A7 (fi) 1993-10-08
EP0579733A1 (en) 1994-01-26
JPH0586057A (ja) 1993-04-06
ATE202352T1 (de) 2001-07-15
DE69231886D1 (de) 2001-07-26
CA2106967C (en) 2003-12-09
NO933615L (no) 1993-10-08
TW209864B (cs) 1993-07-21
EP0579733B1 (en) 2001-06-20
ES2161692T3 (es) 2001-12-16
JP3176694B2 (ja) 2001-06-18
AU1743292A (en) 1992-11-17
KR100249988B1 (ko) 2000-04-01
MX9201637A (es) 1993-08-01
HUT68370A (en) 1995-06-28
GR3036623T3 (en) 2001-12-31

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