FI953717L - 4-Hydroksibentsopyran-2-oneja ja 4-hydroksisykloalkyyli(b)pyran-2-oneja, joita voidaan käyttää retrovirusinfektioiden hoitamiseen - Google Patents

4-Hydroksibentsopyran-2-oneja ja 4-hydroksisykloalkyyli(b)pyran-2-oneja, joita voidaan käyttää retrovirusinfektioiden hoitamiseen Download PDF

Info

Publication number
FI953717L
FI953717L FI953717A FI953717A FI953717L FI 953717 L FI953717 L FI 953717L FI 953717 A FI953717 A FI 953717A FI 953717 A FI953717 A FI 953717A FI 953717 L FI953717 L FI 953717L
Authority
FI
Finland
Prior art keywords
ones
hydroxybenzopyran
hydroxycycloalkyl
pyran
retroviral infections
Prior art date
Application number
FI953717A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI953717A0 (fi
FI953717A7 (fi
Inventor
David John Anderson
Lee S Banitt
Paul Kosta Tomich
Michael John Bohanon
Steven Ronald Turner
Joseph Walter Strohbach
Suvit Thaisrivongs
Chih-Ping Yang
Richard C Thomas
Karen Rene Romines
Paul Adrian Aristoff
Harvey Irving Skulnick
Paul D Johnson
Ronald B Gammill
Qingwei Zhang
Gordon L Bundy
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FI953717L publication Critical patent/FI953717L/fi
Publication of FI953717A0 publication Critical patent/FI953717A0/fi
Publication of FI953717A7 publication Critical patent/FI953717A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/56Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI953717A 1993-02-05 1994-02-03 4-Hydroksibentsopyran-2-oneja ja 4-hydroksisykloalkyyli(b)pyran-2-onej a, joita voidaan käyttää retrovirusinfektioiden hoitamiseen FI953717A7 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1445993A 1993-02-05 1993-02-05
US6871593A 1993-05-27 1993-05-27
US16930293A 1993-12-17 1993-12-17
PCT/US1994/000938 WO1994018188A1 (en) 1993-02-05 1994-02-03 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl[b]pyran-2-ones useful to treat retroviral infections

Publications (3)

Publication Number Publication Date
FI953717L true FI953717L (fi) 1995-08-04
FI953717A0 FI953717A0 (fi) 1995-08-04
FI953717A7 FI953717A7 (fi) 1995-08-04

Family

ID=27360109

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953717A FI953717A7 (fi) 1993-02-05 1994-02-03 4-Hydroksibentsopyran-2-oneja ja 4-hydroksisykloalkyyli(b)pyran-2-onej a, joita voidaan käyttää retrovirusinfektioiden hoitamiseen

Country Status (22)

Country Link
US (1) US5686486A (de)
EP (1) EP0682663B1 (de)
JP (2) JPH08505641A (de)
CN (1) CN1117291A (de)
AT (1) ATE200669T1 (de)
AU (1) AU6166194A (de)
CA (1) CA2153237A1 (de)
CZ (1) CZ9502002A3 (de)
DE (1) DE69427120T2 (de)
DK (1) DK0682663T3 (de)
FI (1) FI953717A7 (de)
GR (1) GR3036189T3 (de)
HU (1) HUT72755A (de)
IL (1) IL108459A0 (de)
LV (1) LV12863B (de)
NO (1) NO953070L (de)
NZ (1) NZ262255A (de)
PL (1) PL310111A1 (de)
PT (1) PT682663E (de)
RU (1) RU2125999C1 (de)
SK (1) SK95695A3 (de)
WO (1) WO1994018188A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637589A (en) * 1993-10-29 1997-06-10 University Of North Carolina At Chapel Hill Suksdorfin, analogs, compositions thereof, and methods for making and using thereof
FI962021A7 (fi) * 1993-11-19 1996-07-12 Parke Davis & Co 5,6-dihydropyronijohdannaiset proteaasi-inhibiittoreina ja antiviraali sina aineina
US5510375A (en) * 1993-11-19 1996-04-23 Warner-Lambert Company Coumarin derivatives as protease inhibitors and antiviral agents
US6005103A (en) * 1993-11-19 1999-12-21 Warner-Lambert Company Pyrone derivatives as protease inhibitors and antiviral agents
US5504104A (en) * 1993-11-19 1996-04-02 Warner-Lambert Company Tricyclic pyrone derivatives as protease inhibitors and antiviral agents
US5840751A (en) * 1993-11-19 1998-11-24 Warner-Lambert Company 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents
US6319929B1 (en) 1994-04-29 2001-11-20 The University Of North Carolina At Chapel Hill Suksdorfin analogs, compositions thereof, and methods for making and using thereof
IL129871A (en) * 1994-05-06 2003-11-23 Pharmacia & Upjohn Inc Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections
PT817786E (pt) * 1995-03-20 2003-06-30 Upjohn Co Acidos tetronicos substituidos uteis para o tratamento do vih e de outros retrovirus
US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
EP0841063A1 (de) * 1996-03-27 1998-05-13 Toray Industries, Inc. Ketonderivate und deren medizinische verwendung
WO1998045246A1 (en) * 1997-04-04 1998-10-15 Teijin Limited Salicylic ester derivatives and process for producing the same
CN1205198C (zh) * 1997-09-26 2005-06-08 东丽株式会社 环酮衍生物及其医药用途
AU2002256361B2 (en) * 2001-04-24 2008-01-24 Arxy Therapeutics Coumarin derivatives to be used as anticoagulants
US7145020B2 (en) * 2001-04-24 2006-12-05 Aryx Therapeutics Materials and methods for treating coagulation disorders
US7018642B2 (en) * 2001-04-27 2006-03-28 The Procter & Gamble Company Compounds, compositions, and methods for controlling biofilms
US7202928B2 (en) * 2003-10-16 2007-04-10 Lg. Philips Lcd Co., Ltd Array substrate for in-plane switching mode liquid crystal display device and method of fabricating the same
JP5036532B2 (ja) * 2004-04-08 2012-09-26 アルメテオン、インコーポレイテッド 血液凝固疾患治療のための物質およびその方法
MXPA06011637A (es) 2004-04-08 2007-05-04 Aryx Therapeutics Materiales y metodos para el tratamiento de trastornos de la coagulacion.
DK2161261T3 (da) * 2004-04-08 2013-11-04 Armetheon Inc Materialer og fremgangsmåder til behandling af koagulationslidelser
AR059339A1 (es) 2006-02-09 2008-03-26 Chugai Pharmaceutical Co Ltd Derivados de la cumarina para trastornos proliferativos de celulas, composicion farmaceutica y agente terapeutico que los contiene
US7939545B2 (en) * 2006-05-16 2011-05-10 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
TWI295288B (en) * 2006-08-17 2008-04-01 Univ Nat Chunghsing New route for the synthesis of benzoxazine
US8569378B2 (en) * 2007-07-20 2013-10-29 Toshiyuki Sakai p27 protein inducer
ATE541841T1 (de) * 2007-11-15 2012-02-15 Boehringer Ingelheim Int Inhibitoren der replikation des human immunodeficiency virus
EA019259B1 (ru) * 2007-11-16 2014-02-28 Джилид Сайенсиз, Инк. Ингибиторы репликации вируса иммунодефицита человека
ES2322121B1 (es) * 2007-12-10 2010-04-19 Consejo Superior De Investigaciones Cientificas Nuevos derivados de aminoacidos dicarboxilicos y su aplicacion en el tratamiento de enfermedades neurodegenerativas.
EP2379504A2 (de) * 2008-12-22 2011-10-26 Sloan Kettering Institute For Cancer Research Verbindungen auf coumarinbasis
CN102040592B (zh) * 2009-10-10 2015-07-15 西南大学 具有抗微生物活性的香豆素唑类化合物、制备方法和医药用途
WO2014089296A2 (en) * 2012-12-06 2014-06-12 Institute For Hepatitis And Virus Research Functionalized benzamide derivatives as antiviral agents against hbv infection
WO2014133059A1 (ja) 2013-02-28 2014-09-04 武田薬品工業株式会社 スルホニルクロライド化合物の製造法
EP2970037A4 (de) 2013-03-15 2016-10-26 Micromidas Inc Verfahren zur herstellung von alkylfuranen
CA2935683A1 (en) * 2013-12-30 2015-07-09 Lifesci Pharmaceuticals, Inc. Therapeutic inhibitory compounds
US10189805B2 (en) * 2014-09-09 2019-01-29 Vanderbilt University Metabolism probes for therapy and diagnosis
CN104374858B (zh) * 2014-11-21 2016-06-29 宜昌人福药业有限责任公司 一种枸橼酸舒芬太尼合成原料及杂质的检测方法
CN105218530B (zh) * 2015-10-20 2019-07-02 青岛农业大学 3-(1-芳基-2-(2-氮杂芳烃)乙基)-4-羟基香豆素及其制备方法
CN109608421A (zh) * 2019-01-22 2019-04-12 河北科技大学 一种5-氨基酮戊酸盐酸盐的合成方法
RU2707103C1 (ru) * 2019-06-15 2019-11-22 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "КОМИ научный центр Уральского отделения Российской академии наук" Кумарины с бициклическими монотерпеновыми заместителями
WO2021158575A1 (en) * 2020-02-03 2021-08-12 Natural Extraction Systems, LLC Compositions related to bioactive agents that convert from anions to molecules
WO2022182523A1 (en) * 2021-02-26 2022-09-01 Natural Extraction Systems, LLC Compositions related to bioactive agents that convert from anions to molecules
CN117326942A (zh) * 2023-09-28 2024-01-02 江苏集萃光敏电子材料研究所有限公司 一种免萃取制备对乙酰氧基苯乙烯的工艺

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL80964C (de) * 1952-03-08
BE519956A (de) * 1952-05-16
US2723277A (en) * 1952-08-26 1955-11-08 Hoffmann La Roche Malonic acid derivatives and process for the manufacture thereof
FR1463767A (fr) * 1963-04-03 1966-07-22 Clin Byla Ets Dérivés de la coumarine et leur préparation
BE674997A (de) * 1965-01-13 1966-07-12
US3489774A (en) * 1967-04-24 1970-01-13 Dow Chemical Co 3-(beta-aryl-beta-(arylthio) (or arylseleno) propionyl)-coumarin products
US3493586A (en) * 1969-01-23 1970-02-03 Dow Chemical Co 3-(beta-aryl-beta-(arylthio) (or arylseleno)-propionyl)pyrone products
US3764693A (en) * 1969-11-21 1973-10-09 Lipha A rodenticidal compositions containing 4-hydroxy coumarins
US3835161A (en) * 1972-10-24 1974-09-10 Realisations Scient S E Res C 3-substituted-4-hydroxy-coumarins
CH648030A5 (de) * 1980-12-15 1985-02-28 Sandoz Ag Benzopyran-allylaminderivate, verfahren zu ihrer herstellung und ihre verwendung.
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
US4701456A (en) * 1984-09-19 1987-10-20 Warner-Lambert Company Aminoalkoxybenzopyranones as antipsychotic and anxiolytic agents
AU1044088A (en) * 1986-12-17 1988-07-15 Nippon Soda Co., Ltd. Heterocyclic compounds having triketo skeleton
JPH03503635A (ja) * 1988-03-01 1991-08-15 ジ・アップジョン・カンパニー ヒトにおいて逆転写酵素を抑制するクマリン類
WO1991004663A1 (en) * 1989-09-26 1991-04-18 The Regents Of The University Of California 6-amino-1,2-benzopyrones useful for treatment of viral diseases
CA2066644A1 (en) * 1989-10-27 1991-04-28 Upjohn Company (The) Method for treating hiv and other retroviruses and compounds useful therefor
JPH03227923A (ja) * 1990-01-30 1991-10-08 Sawai Seiyaku Kk ひと免疫不全ウイルス疾患処置剤
SE9000624D0 (sv) * 1990-02-22 1990-02-22 Pharmacia Ab New use
US5378694A (en) * 1990-09-07 1995-01-03 Schering Corporation Acyl and alkoxy substituted quinolines
JPH06501465A (ja) * 1990-09-07 1994-02-17 シェリング・コーポレーション 抗ウイルス化合物
EP0549729B1 (de) * 1990-09-07 1997-12-17 Schering Corporation Antivirale und antihypertensive verbindungen
JPH06506463A (ja) * 1991-04-04 1994-07-21 ジ・アップジョン・カンパニー Hivおよび他のレトロウイルスの治療に有用な化合物

Also Published As

Publication number Publication date
NO953070L (no) 1995-10-04
DE69427120T2 (de) 2001-08-23
CN1117291A (zh) 1996-02-21
AU6166194A (en) 1994-08-29
CA2153237A1 (en) 1994-08-18
NZ262255A (en) 1997-05-26
CZ9502002A3 (en) 1995-12-13
EP0682663A1 (de) 1995-11-22
US5686486A (en) 1997-11-11
PT682663E (pt) 2001-10-30
DK0682663T3 (da) 2001-06-18
LV12863B (en) 2002-11-20
WO1994018188A1 (en) 1994-08-18
FI953717A0 (fi) 1995-08-04
ATE200669T1 (de) 2001-05-15
JPH08505641A (ja) 1996-06-18
HU9501968D0 (en) 1995-09-28
DE69427120D1 (de) 2001-05-23
FI953717A7 (fi) 1995-08-04
JP2005002133A (ja) 2005-01-06
HUT72755A (en) 1996-05-28
IL108459A0 (en) 1994-04-12
SK95695A3 (en) 1995-12-06
RU2125999C1 (ru) 1999-02-10
NO953070D0 (no) 1995-08-04
GR3036189T3 (en) 2001-10-31
EP0682663B1 (de) 2001-04-18
PL310111A1 (en) 1995-11-27

Similar Documents

Publication Publication Date Title
FI953717L (fi) 4-Hydroksibentsopyran-2-oneja ja 4-hydroksisykloalkyyli(b)pyran-2-oneja, joita voidaan käyttää retrovirusinfektioiden hoitamiseen
FI961030A7 (fi) Epoksidointikatalyytti ja prosessi
FI941378L (fi) Bentsimidatsoliyhdisteitä, niiden käyttö ja valmistus
ATE209916T1 (de) Orale zubereitungen von antimykotika
FI952302L (fi) Pyran-2-onit ja 5,6-dihydropyranonit, jotka ovat käyttökelpoisia HIV:n ja muiden retrovirusten hoidossa
DE59408821D1 (de) Abgasbehandlungsvorrichtung
IT1240078B (it) Procedimento di trattamento di polveri inorganiche.
BR8900962A (pt) Composicao bactericida e processo de tratamento
DE68910799D1 (de) Faserbehandlungszusammensetzung.
DE3788160D1 (de) Plasmabehandlungsvorrichtung.
DK73891D0 (da) Enzymbehandling
BR9202294A (pt) Catalisador,processo de preparacao do mesmo e processo de tratamento de gases contendo compostos sulfurados
BR9105095A (pt) Valvula de comporta corredica,processo e refratarios substituiveis
NO940810D0 (no) Behandling av virusinfeksjoner
FI874939A7 (fi) Antibiotiska foereningar.
FI940425A7 (fi) Modifioidut oligodeoksiribonukleotidit, niiden valmistus ja niiden terapeuttinen käyttö
DE58909062D1 (de) Hochwirksame Polarisatoren.
DE68913088D1 (de) Faserbehandlungszusammensetzung.
DE59007410D1 (de) Hochwirksame Polarisatoren.
BR9302297A (pt) Pista de boliche conversivel,e processo de usa-la
DE3875192D1 (de) Abgasbehandlung.
FI951655A7 (fi) H.pylori -infektioiden hoito
BR8901342A (pt) Polidiorganosiloxano e processo de preparacao do mesmo
DE59702263D1 (de) Reinigung von p.p-Bisphenolat-Lösungen
TR23713A (tr) Suebstituye edilmis tiouereler,izotiouereler ve korbadiimetiller

Legal Events

Date Code Title Description
HC Name/ company changed in application

Owner name: PHARMACIA & UPJOHN COMPANY