FI970357L - Tyypin II diabeteksen hoitoon käyttökelpoisia bensoksatsoli- ja pyridiinijohdannaisia - Google Patents
Tyypin II diabeteksen hoitoon käyttökelpoisia bensoksatsoli- ja pyridiinijohdannaisia Download PDFInfo
- Publication number
- FI970357L FI970357L FI970357A FI970357A FI970357L FI 970357 L FI970357 L FI 970357L FI 970357 A FI970357 A FI 970357A FI 970357 A FI970357 A FI 970357A FI 970357 L FI970357 L FI 970357L
- Authority
- FI
- Finland
- Prior art keywords
- benzoxazole
- diabetes
- treatment
- type
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
| GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
| GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
| PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
| PCT/EP1995/003038 WO1996004260A1 (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI970357A0 FI970357A0 (fi) | 1997-01-28 |
| FI970357A7 FI970357A7 (fi) | 1997-03-26 |
| FI970357L true FI970357L (fi) | 1997-03-26 |
Family
ID=27267309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI970357A FI970357L (fi) | 1994-07-29 | 1995-07-28 | Tyypin II diabeteksen hoitoon käyttökelpoisia bensoksatsoli- ja pyridiinijohdannaisia |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0772605A1 (cs) |
| AP (1) | AP776A (cs) |
| BR (1) | BR9508468A (cs) |
| CA (1) | CA2196079A1 (cs) |
| CZ (1) | CZ25497A3 (cs) |
| DZ (1) | DZ1916A1 (cs) |
| FI (1) | FI970357L (cs) |
| HU (1) | HUT76637A (cs) |
| IL (3) | IL125525A (cs) |
| MA (1) | MA23632A1 (cs) |
| MX (1) | MX9700763A (cs) |
| NO (1) | NO307827B1 (cs) |
| OA (1) | OA10470A (cs) |
| PL (1) | PL318766A1 (cs) |
| SK (1) | SK12297A3 (cs) |
| WO (2) | WO1996004261A1 (cs) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
| RU2169141C2 (ru) * | 1996-04-04 | 2001-06-20 | Санкио Компани Лимитед | Производные фенилалкилкарбоновой кислоты и фармацевтическая композиция на их основе |
| US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
| US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
| PL339660A1 (en) | 1997-10-02 | 2001-01-02 | Sankyo Co | Derivatives of amidocarboxylic acids |
| BR9812772A (pt) | 1997-10-27 | 2000-10-10 | Reddy Research Foundation | "compostos tricìclicos inéditos e o seu emprego na medicina;processo para a sua preparação e composições farmacêuticas contendo os mesmos" |
| CA2307068C (en) | 1997-10-27 | 2007-04-10 | Dr. Reddy's Laboratories Limited | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
| EP1124807A1 (en) * | 1997-10-27 | 2001-08-22 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| US6265401B1 (en) | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
| US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
| US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| JP2002507543A (ja) * | 1998-05-27 | 2002-03-12 | ドクター・レディーズ・リサーチ・ファウンデーション | 二環系化合物、その製造方法およびそれらを含有する薬学的組成物 |
| EE200100155A (et) | 1998-09-17 | 2002-08-15 | Bristol-Myers Squibb Company | Ateroskleroosi ravimeetod, kasutades aP2 inhibiitorit ja selle kombinatsiooni |
| US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
| WO2000023416A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| WO2000023445A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| EP1123269A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU6190199A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
| WO2000023425A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| EP1123297A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
| US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
| UA60386C2 (uk) * | 1998-10-29 | 2003-10-15 | Reddys Laboratories Ltd | Спосіб одержання похідних 3-[4-[2-(феноксазин-10-іл)метокси]феніл]пропіонової кислоти (варіанти) та проміжні сполуки для їх отримання |
| WO2000063189A1 (en) * | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Crystalline r- guanidines, arginine or (l) -arginine (2s) -2- ethoxy -3-{4- [2-(10h -phenoxazin -10-yl)ethoxy]phenyl}propanoate |
| US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
| US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
| EP1171431A1 (en) * | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Compounds, their preparation and use |
| JP2002542246A (ja) | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | 新規な化合物、それらの製造及び使用 |
| HUP0200807A3 (en) * | 1999-04-20 | 2003-03-28 | Novo Nordisk As | Substituted propionic acid derivatives, process for their preparation, pharmaceutical compositions containing them and their use |
| US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| EP1175412A1 (en) | 1999-04-28 | 2002-01-30 | Dr. Reddy's Research Foundation | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents |
| WO2001016120A1 (en) | 1999-08-27 | 2001-03-08 | Eli Lilly And Company | Biaryl-oxa(thia)zole derivatives and their use as ppars modulators |
| ES2449194T3 (es) * | 2000-01-19 | 2014-03-18 | Cadila Healthcare Limited | Compuestos que tienen actividades hipolipidémica e hipocolesterolémica, procedimiento para su preparación y composiciones farmacéuticas que los contienen |
| US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
| PL357017A1 (en) * | 2000-01-28 | 2004-07-12 | Novo Nordisk A/S | Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity |
| US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
| WO2001087860A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Novel benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
| AU2001263083A1 (en) | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4h-benzo(1,4)oxazin-3-ones |
| WO2001087861A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
| US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
| US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
| US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
| US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU2002351752A1 (en) | 2001-12-29 | 2003-07-30 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
| US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
| US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
| US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
| EP2154131A4 (en) * | 2007-04-26 | 2011-09-21 | Pharmafrontier Co Ltd | INHIBITOR OF THE G-PROTEIN-COUPLED RECEPTOR AND PHARMACEUTICAL PRODUCT |
| EP3009136A1 (en) | 2011-01-31 | 2016-04-20 | Cadila Healthcare Limited | Treatment for lipodystrophy |
| UA114360C2 (uk) | 2013-04-22 | 2017-05-25 | Каділа Хелткере Лімітед | Спосіб лікування та/або зменшення інтенсивності неалкогольної жирової хвороби печінки (нжхп) |
| US20160107989A1 (en) | 2013-05-30 | 2016-04-21 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
| TW201513857A (zh) | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | 協同性組成物 |
| IN2013MU02470A (cs) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
| IN2013MU02905A (cs) | 2013-09-06 | 2015-07-03 | Cadila Healthcare Ltd | |
| WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
| EP3551180B1 (en) | 2016-12-09 | 2021-09-29 | Cadila Healthcare Limited | Treatment for primary biliary cholangitis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| SK695A3 (en) * | 1992-07-03 | 1995-07-11 | Smithkline Beecham Plc | Heterocyclic compounds method of their production and using |
-
1995
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en not_active Ceased
- 1995-06-07 BR BR9508468A patent/BR9508468A/pt unknown
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/fr active
- 1995-07-27 IL IL12552595A patent/IL125525A/xx unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/xx unknown
- 1995-07-27 MA MA23972A patent/MA23632A1/fr unknown
- 1995-07-28 HU HU9700264A patent/HUT76637A/hu unknown
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/cs unknown
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 MX MX9700763A patent/MX9700763A/es unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 SK SK122-97A patent/SK12297A3/sk unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Ceased
- 1995-07-28 FI FI970357A patent/FI970357L/fi unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 PL PL95318766A patent/PL318766A1/xx unknown
-
1997
- 1997-01-28 NO NO970373A patent/NO307827B1/no not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI970357A0 (fi) | 1997-01-28 |
| MA23632A1 (fr) | 1996-04-01 |
| CA2196079A1 (en) | 1996-02-15 |
| OA10470A (en) | 2002-04-08 |
| NO970373D0 (no) | 1997-01-28 |
| HUT76637A (en) | 1997-10-28 |
| NO307827B1 (no) | 2000-06-05 |
| CZ25497A3 (en) | 1997-09-17 |
| SK12297A3 (en) | 1997-08-06 |
| PL318766A1 (en) | 1997-07-07 |
| AP9700918A0 (en) | 1997-01-31 |
| DZ1916A1 (fr) | 2002-02-17 |
| FI970357A7 (fi) | 1997-03-26 |
| AP776A (en) | 1999-10-28 |
| IL114759A0 (en) | 1995-12-31 |
| IL114759A (en) | 1999-10-28 |
| WO1996004260A1 (en) | 1996-02-15 |
| WO1996004261A1 (en) | 1996-02-15 |
| NO970373L (no) | 1997-03-18 |
| EP0772605A1 (en) | 1997-05-14 |
| MX9700763A (es) | 1997-05-31 |
| BR9508468A (pt) | 1997-11-25 |
| IL125525A0 (en) | 1999-03-12 |
| IL125525A (en) | 2000-02-29 |
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