FI972794A0 - 6-(triatsolyyli-(3-(trifluorimetyyli)fenyyli)metyyli)-2-kinolinonit ja -kinoliinitionit - Google Patents

6-(triatsolyyli-(3-(trifluorimetyyli)fenyyli)metyyli)-2-kinolinonit ja -kinoliinitionit

Info

Publication number: FI972794A0
Authority: FI; Finland
Prior art keywords: quinolinones; triazolyl; quinoline; trifluoromethyl; ions
Prior art date: 1994-12-28

Application number

FI972794A

Other languages

English (en)

Swedish (sv)

Other versions

FI972794A7 (fi

FI972794L (fi

Inventor

Marc Gaston Venet

Dominique Jean-Pierre Mabire

Gerard Charles Sanz

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-28

Filing date

1995-12-21

Publication date

1997-06-27

1995-12-21 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1997-06-27 Publication of FI972794A7 publication Critical patent/FI972794A7/fi

1997-06-27 Publication of FI972794A0 publication Critical patent/FI972794A0/fi

1997-06-27 Publication of FI972794L publication Critical patent/FI972794L/fi

Links

VQADDUMCOHBRLR-UHFFFAOYSA-N N1N=NC(=C1)C(C=1C=C2C=CC(NC2=CC1)=O)C1=CC(=CC=C1)C(F)(F)F Chemical class N1N=NC(=C1)C(C=1C=C2C=CC(NC2=CC1)=O)C1=CC(=CC=C1)C(F)(F)F VQADDUMCOHBRLR-UHFFFAOYSA-N 0.000 title 1
SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 1
-1 quinoline ions Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cosmetics (AREA)

FI972794A 1994-12-28 1995-12-21 6-(triatsolyyli-(3-(trifluorimetyyli)fenyyli)metyyli)-2-kinolinonit ja -kinoliinitionit FI972794L (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP94203773		1994-12-28
PCT/EP1995/005173 WO1996020200A1 (en)	1994-12-28	1995-12-21	6-[triazolyl[3-(trifluoromethyl)phenyl]methyl]-2-quinolinones and -quinolinethiones

Publications (3)

Publication Number	Publication Date
FI972794A7 FI972794A7 (fi)	1997-06-27
FI972794A0 true FI972794A0 (fi)	1997-06-27
FI972794L FI972794L (fi)	1997-06-27

Family

ID=8217501

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI972794A FI972794L (fi)	1994-12-28	1995-12-21	6-(triatsolyyli-(3-(trifluorimetyyli)fenyyli)metyyli)-2-kinolinonit ja -kinoliinitionit

Country Status (25)

Country	Link
US (1)	US5922734A (fi)
EP (1)	EP0800524B1 (fi)
JP (1)	JPH10511654A (fi)
CN (1)	CN1085668C (fi)
AR (1)	AR002264A1 (fi)
AT (1)	ATE207924T1 (fi)
AU (1)	AU698199B2 (fi)
BR (1)	BR9510504A (fi)
CA (1)	CA2207268A1 (fi)
DE (1)	DE69523629T2 (fi)
DK (1)	DK0800524T3 (fi)
ES (1)	ES2166838T3 (fi)
FI (1)	FI972794L (fi)
HR (1)	HRP950616A2 (fi)
IL (1)	IL116577A (fi)
MY (1)	MY131690A (fi)
NO (1)	NO311220B1 (fi)
NZ (1)	NZ298789A (fi)
PL (1)	PL182956B1 (fi)
PT (1)	PT800524E (fi)
RU (1)	RU2165419C2 (fi)
TR (1)	TR199501688A2 (fi)
TW (1)	TW316902B (fi)
WO (1)	WO1996020200A1 (fi)
ZA (1)	ZA9510989B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW591030B (en)	1997-03-10	2004-06-11	Janssen Pharmaceutica Nv	Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
AU4822299A (en) *	1998-06-16	2000-01-05	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.)	Imidazolyl derivatives
US6420555B1 (en)	1998-06-16	2002-07-16	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Imidazolyl derivatives
EP1420015A1 (en) *	1999-06-11	2004-05-19	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S.	Imidazolyl derivatives
DE60139080D1 (de) *	2000-11-21	2009-08-06	Janssen Pharmaceutica Nv	Farnesyltransferase hemmende benzoheterocyclische derivate
WO2002043733A1 (en) *	2000-11-28	2002-06-06	Janssen Pharmaceutica N.V.	Farnesyl protein transferase inhibitors for the treatment of inflammatory bowel disease
US20040067968A1 (en) *	2000-12-27	2004-04-08	Angibaud Patrick Rene	Farnesyl transferase inhibiting 4-heterocyclyl quinoline and quinazoline
WO2002051835A1 (en) *	2000-12-27	2002-07-04	Janssen Pharmaceutica N.V.	Farnesyl transferase inhibiting 4-substituted quinoline and quinazoline derivatives
US8232402B2 (en) *	2008-03-12	2012-07-31	Link Medicine Corporation	Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7908031A (nl) *	1979-11-01	1981-06-01	Acf Chemiefarma Nv	Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
US4792561A (en) *	1986-05-29	1988-12-20	Syntex (U.S.A.) Inc.	Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
US4859684A (en) *	1986-09-15	1989-08-22	Janssen Pharmaceutica N.V.	(1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders
NZ221729A (en) *	1986-09-15	1989-07-27	Janssen Pharmaceutica Nv	Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
ES2070151T3 (es) *	1988-08-10	1995-06-01	Otsuka Pharma Co Ltd	Agentes cardiotonicos.
CA2002864C (en) *	1988-11-29	1999-11-16	Eddy J. E. Freyne	(1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives
CA2002859C (en) *	1988-11-29	1998-12-29	Jean P. F. Van Wauwe	Method of treating epithelial disorders
US5185346A (en) *	1988-11-29	1993-02-09	Hanssen Pharmaceutica	(1H-azol-1-ylmethyl)substituted quinoline derivatives
US5157046A (en) *	1988-11-29	1992-10-20	Janssen Pharmaceutica N.V.	Method of treating epithelial disorders
GB8827822D0 (en) *	1988-11-29	1988-12-29	Janssen Pharmaceutica Nv	(1h-azol-1-ylmethyl)substituted quinoline derivatives
CA2015267A1 (en) *	1989-05-26	1990-11-26	Rainer Seele	8-azolylmethylquinolines

1995
- 1995-12-20 TW TW084113605A patent/TW316902B/zh active
- 1995-12-21 CN CN95197162A patent/CN1085668C/zh not_active Expired - Fee Related
- 1995-12-21 DE DE69523629T patent/DE69523629T2/de not_active Expired - Fee Related
- 1995-12-21 DK DK95943237T patent/DK0800524T3/da active
- 1995-12-21 CA CA002207268A patent/CA2207268A1/en not_active Abandoned
- 1995-12-21 AU AU44362/96A patent/AU698199B2/en not_active Ceased
- 1995-12-21 RU RU97112898/04A patent/RU2165419C2/ru not_active IP Right Cessation
- 1995-12-21 EP EP95943237A patent/EP0800524B1/en not_active Expired - Lifetime
- 1995-12-21 NZ NZ298789A patent/NZ298789A/xx unknown
- 1995-12-21 PL PL95321041A patent/PL182956B1/pl unknown
- 1995-12-21 US US08/860,239 patent/US5922734A/en not_active Expired - Fee Related
- 1995-12-21 AT AT95943237T patent/ATE207924T1/de not_active IP Right Cessation
- 1995-12-21 WO PCT/EP1995/005173 patent/WO1996020200A1/en not_active Ceased
- 1995-12-21 ES ES95943237T patent/ES2166838T3/es not_active Expired - Lifetime
- 1995-12-21 FI FI972794A patent/FI972794L/fi unknown
- 1995-12-21 JP JP8520222A patent/JPH10511654A/ja active Pending
- 1995-12-21 PT PT95943237T patent/PT800524E/pt unknown
- 1995-12-21 BR BR9510504A patent/BR9510504A/pt not_active Application Discontinuation
- 1995-12-22 HR HR94203773.0A patent/HRP950616A2/hr not_active Application Discontinuation
- 1995-12-27 IL IL11657795A patent/IL116577A/xx not_active IP Right Cessation
- 1995-12-27 ZA ZA9510989A patent/ZA9510989B/xx unknown
- 1995-12-27 TR TR95/01688A patent/TR199501688A2/xx unknown
- 1995-12-27 AR ARP950100795A patent/AR002264A1/es unknown
- 1995-12-28 MY MYPI95004141A patent/MY131690A/en unknown
1997
- 1997-06-27 NO NO19973029A patent/NO311220B1/no unknown

Also Published As

Publication number	Publication date
FI972794A7 (fi)	1997-06-27
JPH10511654A (ja)	1998-11-10
NO973029L (no)	1997-06-27
US5922734A (en)	1999-07-13
PL321041A1 (en)	1997-11-24
WO1996020200A1 (en)	1996-07-04
EP0800524A1 (en)	1997-10-15
ATE207924T1 (de)	2001-11-15
PT800524E (pt)	2002-04-29
CN1085668C (zh)	2002-05-29
MX9704667A (es)	1997-09-30
AU698199B2 (en)	1998-10-29
ES2166838T3 (es)	2002-05-01
NO311220B1 (no)	2001-10-29
NZ298789A (en)	1999-07-29
BR9510504A (pt)	1999-06-01
DK0800524T3 (da)	2002-03-25
NO973029D0 (no)	1997-06-27
ZA9510989B (en)	1997-06-27
MY131690A (en)	2007-08-30
DE69523629D1 (de)	2001-12-06
CA2207268A1 (en)	1996-07-04
IL116577A0 (en)	1996-03-31
AR002264A1 (es)	1998-03-11
HRP950616A2 (en)	1997-10-31
AU4436296A (en)	1996-07-19
EP0800524B1 (en)	2001-10-31
CN1171789A (zh)	1998-01-28
IL116577A (en)	2000-02-29
DE69523629T2 (de)	2002-07-18
RU2165419C2 (ru)	2001-04-20
TR199501688A2 (tr)	1996-07-21
PL182956B1 (pl)	2002-05-31
TW316902B (fi)	1997-10-01
FI972794L (fi)	1997-06-27

Publication	Publication Date	Title
NO20012579L (no)	2001-07-19	Kinolin- og kinoksalinforbindelser
DK1095021T3 (da)	2003-11-24	Quinolinderivater
MA26774A1 (fr)	2004-12-20	Derives de pyridinyl et de phenyl
IS2082B (is)	2006-02-15	Kvínólínafleiður
PT907650E (pt)	2003-04-30	N-¬4-(heteroarilmetil)fenil\|heteroarilaminasc
FI982407A0 (fi)	1998-11-06	Toimielimet ja laitteet
DE69943406D1 (de)	2011-06-16	Abstandsmesser und kamera
NO20013003D0 (no)	2001-06-15	Kinolin-derivater
TR199501305A2 (tr)	1996-06-21	Heterosiklik bilesikler ve bunlarin hazirlanmasi ve kullanimi
DE69803974D1 (de)	2002-04-04	Netzzugriffsverfahren mit direktem drahtlosem internetzugriff
DE69904333D1 (de)	2003-01-16	Chinolinderivate
FI972794A7 (fi)	1997-06-27	6-(triatsolyyli-(3-(trifluorimetyyli)fenyyli)metyyli)-2-kinolinonit ja -kinoliinitionit
NO952171D0 (no)	1995-06-01	3-heteroalifatyl- og 3-hetero(aryl)alifatyl-2(1H)-chinolon-derivater
FI963531A7 (fi)	1996-09-09	Kinoliini-3-karboksamidiyhdisteiden uusi käyttö
DE19882085D2 (de)	2000-08-24	Kühl- und Heizkern
FI963532A7 (fi)	1996-11-06	Kinoliini-3-karboksamidiyhdisteiden uusi käyttö
NZ301453A (en)	1999-02-25	4-(substituted phenyl),4-(substituted carboxyl, carboxylamide or alkyl)-cyclohexan-1-one derivatives and medicaments
FI941583A0 (fi)	1994-04-06	Foerfarande och anordning foer reglering av temperatur i transportcontainer
FI980212A0 (fi)	1998-01-30	Anordning och foerfarande foer infoerande av en massabanas spets i en cellulosatork
FI980760A0 (fi)	1998-04-02	Serversystem och foerfarande foer anvaendning av serversystemet
FI980682A0 (fi)	1998-03-26	Foerfarande och anordning i en fiberbelaeggningslinje
FI941501A0 (fi)	1994-03-30	Kula och foerfarande foer framstaellning av kulor
FI972894A0 (fi)	1997-07-08	Foerfarande och anordning foer relgering av valsarnas temperatur i en horisontalhaerdningsanordning foer glasskivor
KR970060300U (ko)	1997-12-10	매트훈증기