NO973029L - 6-£triazolyl£3-(trifluormetyl)fenyl|metyl|-2-kinolinoner og -kinolintioner - Google Patents

6-£triazolyl£3-(trifluormetyl)fenyl|metyl|-2-kinolinoner og -kinolintioner

Info

Publication number
NO973029L
NO973029L NO973029A NO973029A NO973029L NO 973029 L NO973029 L NO 973029L NO 973029 A NO973029 A NO 973029A NO 973029 A NO973029 A NO 973029A NO 973029 L NO973029 L NO 973029L
Authority
NO
Norway
Prior art keywords
intions
quinolinones
triazolyl
quinoline
trifluoromethyl
Prior art date
Application number
NO973029A
Other languages
English (en)
Other versions
NO311220B1 (no
NO973029D0 (no
Inventor
Marc Gaston Venet
Dominique Jean-Pierre Mabire
Gerard Charles Sanz
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO973029L publication Critical patent/NO973029L/no
Publication of NO973029D0 publication Critical patent/NO973029D0/no
Publication of NO311220B1 publication Critical patent/NO311220B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
NO19973029A 1994-12-28 1997-06-27 6-[triazolyl[3-(trifluormetyl)fenyl]metyl]-2-kinolinoner og - kinolintioner NO311220B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94203773 1994-12-28
PCT/EP1995/005173 WO1996020200A1 (en) 1994-12-28 1995-12-21 6-[triazolyl[3-(trifluoromethyl)phenyl]methyl]-2-quinolinones and -quinolinethiones

Publications (3)

Publication Number Publication Date
NO973029L true NO973029L (no) 1997-06-27
NO973029D0 NO973029D0 (no) 1997-06-27
NO311220B1 NO311220B1 (no) 2001-10-29

Family

ID=8217501

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19973029A NO311220B1 (no) 1994-12-28 1997-06-27 6-[triazolyl[3-(trifluormetyl)fenyl]metyl]-2-kinolinoner og - kinolintioner

Country Status (25)

Country Link
US (1) US5922734A (no)
EP (1) EP0800524B1 (no)
JP (1) JPH10511654A (no)
CN (1) CN1085668C (no)
AR (1) AR002264A1 (no)
AT (1) ATE207924T1 (no)
AU (1) AU698199B2 (no)
BR (1) BR9510504A (no)
CA (1) CA2207268A1 (no)
DE (1) DE69523629T2 (no)
DK (1) DK0800524T3 (no)
ES (1) ES2166838T3 (no)
FI (1) FI972794A7 (no)
HR (1) HRP950616A2 (no)
IL (1) IL116577A (no)
MY (1) MY131690A (no)
NO (1) NO311220B1 (no)
NZ (1) NZ298789A (no)
PL (1) PL182956B1 (no)
PT (1) PT800524E (no)
RU (1) RU2165419C2 (no)
TR (1) TR199501688A2 (no)
TW (1) TW316902B (no)
WO (1) WO1996020200A1 (no)
ZA (1) ZA9510989B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW591030B (en) 1997-03-10 2004-06-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
CA2335435A1 (en) * 1998-06-16 1999-12-23 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R Imidazolyl derivatives
US6420555B1 (en) 1998-06-16 2002-07-16 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Imidazolyl derivatives
EP1420015A1 (en) * 1999-06-11 2004-05-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Imidazolyl derivatives
AU2002214056A1 (en) * 2000-11-21 2002-06-03 Janssen Pharmaceutica N.V. Farnesyl transferase inhibiting benzoheterocyclic derivatives
DE60118953T2 (de) * 2000-11-28 2007-01-11 Janssen Pharmaceutica N.V. Farnesyl-protein-transferasehemmer zur behandlung der entzündlichen darmerkrankung
JP4351445B2 (ja) * 2000-12-27 2009-10-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ファルネシルトランスフェラーゼを阻害する４−置換−キノリンおよびキナゾリン誘導体
US20040067968A1 (en) * 2000-12-27 2004-04-08 Angibaud Patrick Rene Farnesyl transferase inhibiting 4-heterocyclyl quinoline and quinazoline
WO2009151683A2 (en) * 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908031A (nl) * 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
US4792561A (en) * 1986-05-29 1988-12-20 Syntex (U.S.A.) Inc. Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
NZ221729A (en) * 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
US4859684A (en) * 1986-09-15 1989-08-22 Janssen Pharmaceutica N.V. (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders
DK391189A (da) * 1988-08-10 1990-02-11 Otsuka Pharma Co Ltd Carbostyrilderivater
GB8827822D0 (en) * 1988-11-29 1988-12-29 Janssen Pharmaceutica Nv (1h-azol-1-ylmethyl)substituted quinoline derivatives
CA2002864C (en) * 1988-11-29 1999-11-16 Eddy J. E. Freyne (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives
CA2002859C (en) * 1988-11-29 1998-12-29 Jean P. F. Van Wauwe Method of treating epithelial disorders
US5185346A (en) * 1988-11-29 1993-02-09 Hanssen Pharmaceutica (1H-azol-1-ylmethyl)substituted quinoline derivatives
US5157046A (en) * 1988-11-29 1992-10-20 Janssen Pharmaceutica N.V. Method of treating epithelial disorders
CA2015267A1 (en) * 1989-05-26 1990-11-26 Rainer Seele 8-azolylmethylquinolines

Also Published As

Publication number Publication date
PL321041A1 (en) 1997-11-24
HRP950616A2 (en) 1997-10-31
EP0800524B1 (en) 2001-10-31
IL116577A0 (en) 1996-03-31
ZA9510989B (en) 1997-06-27
DE69523629T2 (de) 2002-07-18
FI972794L (fi) 1997-06-27
ES2166838T3 (es) 2002-05-01
CA2207268A1 (en) 1996-07-04
AU698199B2 (en) 1998-10-29
WO1996020200A1 (en) 1996-07-04
JPH10511654A (ja) 1998-11-10
CN1085668C (zh) 2002-05-29
IL116577A (en) 2000-02-29
FI972794A0 (fi) 1997-06-27
RU2165419C2 (ru) 2001-04-20
PT800524E (pt) 2002-04-29
NZ298789A (en) 1999-07-29
MX9704667A (es) 1997-09-30
US5922734A (en) 1999-07-13
AU4436296A (en) 1996-07-19
EP0800524A1 (en) 1997-10-15
FI972794A7 (fi) 1997-06-27
TW316902B (no) 1997-10-01
ATE207924T1 (de) 2001-11-15
PL182956B1 (pl) 2002-05-31
MY131690A (en) 2007-08-30
BR9510504A (pt) 1999-06-01
NO311220B1 (no) 2001-10-29
DE69523629D1 (de) 2001-12-06
AR002264A1 (es) 1998-03-11
TR199501688A2 (tr) 1996-07-21
CN1171789A (zh) 1998-01-28
DK0800524T3 (da) 2002-03-25
NO973029D0 (no) 1997-06-27

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