FI972794A7 - 6-(triazolyl-(3-(trifluormetyl)fenyl)metyl)-2-kinolinoner och -kinolin tioner - Google Patents

6-(triazolyl-(3-(trifluormetyl)fenyl)metyl)-2-kinolinoner och -kinolin tioner Download PDF

Info

Publication number
FI972794A7
FI972794A7 FI972794A FI972794A FI972794A7 FI 972794 A7 FI972794 A7 FI 972794A7 FI 972794 A FI972794 A FI 972794A FI 972794 A FI972794 A FI 972794A FI 972794 A7 FI972794 A7 FI 972794A7
Authority
FI
Finland
Prior art keywords
quinolinethiones
quinolinones
triazolyl
trifluoromethyl
phenyl
Prior art date
Application number
FI972794A
Other languages
English (en)
Finnish (fi)
Other versions
FI972794A0 (sv
FI972794L (sv
Inventor
Marc Gaston Venet
Dominique Jean-Pierre Mabire
Gerard Charles Sanz
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI972794A7 publication Critical patent/FI972794A7/sv
Publication of FI972794A0 publication Critical patent/FI972794A0/sv
Publication of FI972794L publication Critical patent/FI972794L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
FI972794A 1994-12-28 1995-12-21 6-(triazolyl-(3-(trifluormetyl)fenyl)metyl)-2-kinolinoner och -kinolintioner FI972794L (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94203773 1994-12-28
PCT/EP1995/005173 WO1996020200A1 (en) 1994-12-28 1995-12-21 6-[triazolyl[3-(trifluoromethyl)phenyl]methyl]-2-quinolinones and -quinolinethiones

Publications (3)

Publication Number Publication Date
FI972794A7 true FI972794A7 (sv) 1997-06-27
FI972794A0 FI972794A0 (sv) 1997-06-27
FI972794L FI972794L (sv) 1997-06-27

Family

ID=8217501

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972794A FI972794L (sv) 1994-12-28 1995-12-21 6-(triazolyl-(3-(trifluormetyl)fenyl)metyl)-2-kinolinoner och -kinolintioner

Country Status (25)

Country Link
US (1) US5922734A (sv)
EP (1) EP0800524B1 (sv)
JP (1) JPH10511654A (sv)
CN (1) CN1085668C (sv)
AR (1) AR002264A1 (sv)
AT (1) ATE207924T1 (sv)
AU (1) AU698199B2 (sv)
BR (1) BR9510504A (sv)
CA (1) CA2207268A1 (sv)
DE (1) DE69523629T2 (sv)
DK (1) DK0800524T3 (sv)
ES (1) ES2166838T3 (sv)
FI (1) FI972794L (sv)
HR (1) HRP950616A2 (sv)
IL (1) IL116577A (sv)
MY (1) MY131690A (sv)
NO (1) NO311220B1 (sv)
NZ (1) NZ298789A (sv)
PL (1) PL182956B1 (sv)
PT (1) PT800524E (sv)
RU (1) RU2165419C2 (sv)
TR (1) TR199501688A2 (sv)
TW (1) TW316902B (sv)
WO (1) WO1996020200A1 (sv)
ZA (1) ZA9510989B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW591030B (en) 1997-03-10 2004-06-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
AU4822299A (en) * 1998-06-16 2000-01-05 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Imidazolyl derivatives
US6420555B1 (en) 1998-06-16 2002-07-16 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Imidazolyl derivatives
EP1420015A1 (en) * 1999-06-11 2004-05-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Imidazolyl derivatives
DE60139080D1 (de) * 2000-11-21 2009-08-06 Janssen Pharmaceutica Nv Farnesyltransferase hemmende benzoheterocyclische derivate
WO2002043733A1 (en) * 2000-11-28 2002-06-06 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitors for the treatment of inflammatory bowel disease
US20040067968A1 (en) * 2000-12-27 2004-04-08 Angibaud Patrick Rene Farnesyl transferase inhibiting 4-heterocyclyl quinoline and quinazoline
WO2002051835A1 (en) * 2000-12-27 2002-07-04 Janssen Pharmaceutica N.V. Farnesyl transferase inhibiting 4-substituted quinoline and quinazoline derivatives
US8232402B2 (en) * 2008-03-12 2012-07-31 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908031A (nl) * 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
US4792561A (en) * 1986-05-29 1988-12-20 Syntex (U.S.A.) Inc. Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
US4859684A (en) * 1986-09-15 1989-08-22 Janssen Pharmaceutica N.V. (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders
NZ221729A (en) * 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
ES2070151T3 (es) * 1988-08-10 1995-06-01 Otsuka Pharma Co Ltd Agentes cardiotonicos.
CA2002864C (en) * 1988-11-29 1999-11-16 Eddy J. E. Freyne (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives
CA2002859C (en) * 1988-11-29 1998-12-29 Jean P. F. Van Wauwe Method of treating epithelial disorders
US5185346A (en) * 1988-11-29 1993-02-09 Hanssen Pharmaceutica (1H-azol-1-ylmethyl)substituted quinoline derivatives
US5157046A (en) * 1988-11-29 1992-10-20 Janssen Pharmaceutica N.V. Method of treating epithelial disorders
GB8827822D0 (en) * 1988-11-29 1988-12-29 Janssen Pharmaceutica Nv (1h-azol-1-ylmethyl)substituted quinoline derivatives
CA2015267A1 (en) * 1989-05-26 1990-11-26 Rainer Seele 8-azolylmethylquinolines

Also Published As

Publication number Publication date
JPH10511654A (ja) 1998-11-10
NO973029L (no) 1997-06-27
US5922734A (en) 1999-07-13
PL321041A1 (en) 1997-11-24
WO1996020200A1 (en) 1996-07-04
EP0800524A1 (en) 1997-10-15
FI972794A0 (sv) 1997-06-27
ATE207924T1 (de) 2001-11-15
PT800524E (pt) 2002-04-29
CN1085668C (zh) 2002-05-29
MX9704667A (es) 1997-09-30
AU698199B2 (en) 1998-10-29
ES2166838T3 (es) 2002-05-01
NO311220B1 (no) 2001-10-29
NZ298789A (en) 1999-07-29
BR9510504A (pt) 1999-06-01
DK0800524T3 (da) 2002-03-25
NO973029D0 (no) 1997-06-27
ZA9510989B (en) 1997-06-27
MY131690A (en) 2007-08-30
DE69523629D1 (de) 2001-12-06
CA2207268A1 (en) 1996-07-04
IL116577A0 (en) 1996-03-31
AR002264A1 (es) 1998-03-11
HRP950616A2 (en) 1997-10-31
AU4436296A (en) 1996-07-19
EP0800524B1 (en) 2001-10-31
CN1171789A (zh) 1998-01-28
IL116577A (en) 2000-02-29
DE69523629T2 (de) 2002-07-18
RU2165419C2 (ru) 2001-04-20
TR199501688A2 (tr) 1996-07-21
PL182956B1 (pl) 2002-05-31
TW316902B (sv) 1997-10-01
FI972794L (sv) 1997-06-27

Similar Documents

Publication Publication Date Title
PT907650E (pt) N-¬4-(heteroarilmetil)fenil|heteroarilaminasc
TR199501305A2 (tr) Heterosiklik bilesikler ve bunlarin hazirlanmasi ve kullanimi
FI982407A0 (sv) Manöveringsorgan och anordningar
FI971489A7 (sv) Nya benzoxazoler
MA26774A1 (fr) Derives de pyridinyl et de phenyl
ID17053A (id) Derivat-derivat 2-(2-okso-etiliden)-imidazolidin-4-on
EE04849B1 (et) Asendatud fenüülderivaadid, nende valmistamine jakasutamine
DE69739950D1 (de) Kaugummi enthaltend azyklische carboxamide mit kontrollierter freisetzung
EE9800378A (et) Alküülaminobensotiasooli ja -bensoksasooli derivaadid
EP0983958A4 (en) ESCALATOR STAGE AND ESCALATOR
FI972794L (sv) 6-(triazolyl-(3-(trifluormetyl)fenyl)metyl)-2-kinolinoner och -kinolintioner
FI971376A0 (fi) Trofinin och trofininmedlande proteiner
NZ301453A (en) 4-(substituted phenyl),4-(substituted carboxyl, carboxylamide or alkyl)-cyclohexan-1-one derivatives and medicaments
DE69610440D1 (de) Phenylacetamid-derivate
DE59509813D1 (de) Substituierte oxazoline
FI941583A0 (fi) Foerfarande och anordning foer reglering av temperatur i transportcontainer
FI944556A0 (fi) Foerfarande foer producering av antracykliner och deras mellanprodukter
NO975651D0 (no) Fotoperm
FI972894A0 (fi) Foerfarande och anordning foer relgering av valsarnas temperatur i en horisontalhaerdningsanordning foer glasskivor
FI962741A0 (fi) Sollins och braennpunktsvaermare i kombination med vaermeackumulator
FI974202A0 (fi) Anordning och foerfarande foer tvaettning av smutsiga konstruktioner
MA23398A1 (fr) 3-(Benzyl-substitue)-1-Methyl-6-TrifluorMethylurAciles HERBICIDES
FI960008A0 (fi) Foerfarande och anordning med vilken en jonproduktionselektrod haolls ren
FI971581A0 (fi) Foerfarande foer portionering och aoteruppvaermning i fibertarm av olika i faststaellt vikt utportionerade snabbmatsfyllningar
KR970053437U (ko) 휴대와 사용이 간편한 1회용 풍로