FR2361392A1 - Nouveaux 2,2-diaryl-3-(1-aza-2-bicyclo(2.2.2)octyl)propionamides utiles notamment comme agents antidiarrheiques et leur procede de preparation - Google Patents

Nouveaux 2,2-diaryl-3-(1-aza-2-bicyclo(2.2.2)octyl)propionamides utiles notamment comme agents antidiarrheiques et leur procede de preparation

Info

Publication number
FR2361392A1
FR2361392A1 FR7706831A FR7706831A FR2361392A1 FR 2361392 A1 FR2361392 A1 FR 2361392A1 FR 7706831 A FR7706831 A FR 7706831A FR 7706831 A FR7706831 A FR 7706831A FR 2361392 A1 FR2361392 A1 FR 2361392A1
Authority
FR
France
Prior art keywords
propionamides
diaryl
aza
bicyclo
octyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7706831A
Other languages
English (en)
Other versions
FR2361392B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of FR2361392A1 publication Critical patent/FR2361392A1/fr
Application granted granted Critical
Publication of FR2361392B1 publication Critical patent/FR2361392B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Les nouveaux médicaments répondent à la formule générale :
FR7706831A 1976-03-08 1977-03-08 Nouveaux 2,2-diaryl-3-(1-aza-2-bicyclo(2.2.2)octyl)propionamides utiles notamment comme agents antidiarrheiques et leur procede de preparation Granted FR2361392A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/664,723 US4013667A (en) 1976-03-08 1976-03-08 2,2-Diaryl-3-(1-azabicyclo[2.2.2]oct-2-yl)propionamides and intermediates thereto

Publications (2)

Publication Number Publication Date
FR2361392A1 true FR2361392A1 (fr) 1978-03-10
FR2361392B1 FR2361392B1 (fr) 1980-06-06

Family

ID=24667198

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7706831A Granted FR2361392A1 (fr) 1976-03-08 1977-03-08 Nouveaux 2,2-diaryl-3-(1-aza-2-bicyclo(2.2.2)octyl)propionamides utiles notamment comme agents antidiarrheiques et leur procede de preparation

Country Status (7)

Country Link
US (1) US4013667A (fr)
JP (1) JPS52108998A (fr)
AU (1) AU507624B2 (fr)
CA (1) CA1086738A (fr)
DE (1) DE2709851A1 (fr)
FR (1) FR2361392A1 (fr)
GB (1) GB1526184A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125531A (en) * 1977-04-18 1978-11-14 G. D. Searle & Co. 2-Substituted-1-azabicyclo[2.2.2]octanes
US4203989A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal diaryl-(1-azabicyclo(2.2.2)octan-2-yl)-alkanols and related compounds
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
US5242930A (en) * 1991-02-11 1993-09-07 Merck Sharp & Dohme Ltd. Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833592A (en) * 1966-05-31 1974-09-03 Little Inc A Tropanyl alpha,alpha-diphenyl-alpha-fluoroacetate esters
US3542791A (en) * 1968-07-25 1970-11-24 Upjohn Co 2-phenyl-3-(3-quinuclidinylamino)-propiophenones
US3560510A (en) * 1969-03-05 1971-02-02 Aldrich Chem Co Inc 2-benzhydrylquinuclidines

Also Published As

Publication number Publication date
CA1086738A (fr) 1980-09-30
JPS52108998A (en) 1977-09-12
GB1526184A (en) 1978-09-27
US4013667A (en) 1977-03-22
AU507624B2 (en) 1980-02-21
DE2709851A1 (de) 1977-09-15
FR2361392B1 (fr) 1980-06-06
AU2296777A (en) 1978-09-14

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Legal Events

Date Code Title Description
ST Notification of lapse