FR2361412A1 - Systeme enzymatique scindant le fibrinogene - Google Patents

Systeme enzymatique scindant le fibrinogene

Info

Publication number
FR2361412A1
FR2361412A1 FR7710776A FR7710776A FR2361412A1 FR 2361412 A1 FR2361412 A1 FR 2361412A1 FR 7710776 A FR7710776 A FR 7710776A FR 7710776 A FR7710776 A FR 7710776A FR 2361412 A1 FR2361412 A1 FR 2361412A1
Authority
FR
France
Prior art keywords
enzymatic system
fibrinogen
fibrinogen split
solution
split
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7710776A
Other languages
English (en)
Other versions
FR2361412B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Publication of FR2361412A1 publication Critical patent/FR2361412A1/fr
Application granted granted Critical
Publication of FR2361412B1 publication Critical patent/FR2361412B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/14—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar alpha-D-Glucans, i.e. having alpha 1,n (n=3,4,6) linkages between saccharide units, e.g. pullulan
    • G01N2400/22—Dextran

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

a. L'invention concerne un système enzymatique capable de scinder le fibrinogène. b. On augmente considérablement l'efficacité des fibrinogénases en ajoutant à leur solution une solution d'un polysaccharide hydrosoluble. c. La combinaison des deux produits peut être utilisée pour établir des diagnostics et pour traiter les troubles de la circulation sanguine périphérique.
FR7710776A 1976-04-10 1977-04-08 Systeme enzymatique scindant le fibrinogene Granted FR2361412A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762615844 DE2615844A1 (de) 1976-04-10 1976-04-10 Fibrinogen spaltendes enzymsystem

Publications (2)

Publication Number Publication Date
FR2361412A1 true FR2361412A1 (fr) 1978-03-10
FR2361412B1 FR2361412B1 (fr) 1980-04-04

Family

ID=5975094

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7710776A Granted FR2361412A1 (fr) 1976-04-10 1977-04-08 Systeme enzymatique scindant le fibrinogene

Country Status (11)

Country Link
US (1) US4154656A (fr)
JP (1) JPS52125689A (fr)
AT (1) AT353423B (fr)
BE (1) BE852758A (fr)
DE (1) DE2615844A1 (fr)
DK (1) DK158677A (fr)
FR (1) FR2361412A1 (fr)
GB (1) GB1519285A (fr)
IE (1) IE44735B1 (fr)
LU (1) LU77089A1 (fr)
NL (1) NL7703444A (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3330699A1 (de) * 1983-08-25 1985-03-07 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur gleichzeitigen bestimmung von fibrinogen und fibrinogen-spaltprodukten im plasma
DE3841736A1 (de) * 1988-12-10 1990-07-05 Basf Ag Ancrod-proteine, ihre herstellung und verwendung
EP2029740B1 (fr) * 2006-05-31 2012-06-20 Genzyme Corporation Utilisation de polysaccharides pour faciliter une activité enzymatique
US8178145B1 (en) 2007-11-14 2012-05-15 JMC Enterprises, Inc. Methods and systems for applying sprout inhibitors and/or other substances to harvested potatoes and/or other vegetables in storage facilities
US9605890B2 (en) 2010-06-30 2017-03-28 Jmc Ventilation/Refrigeration, Llc Reverse cycle defrost method and apparatus
US10076129B1 (en) 2016-07-15 2018-09-18 JMC Enterprises, Inc. Systems and methods for inhibiting spoilage of stored crops

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH586233A5 (fr) * 1971-01-18 1977-03-31 Pentapharm Ag
GB1479268A (en) * 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
US3819605A (en) * 1973-08-17 1974-06-25 Abbott Lab Anticoagulant isolation from pit viper using a modified agarose bed and eluting with a benzamidine solution
SE420321B (sv) * 1973-09-03 1981-09-28 Fargal Pharmasint Lab Biochim Kromatografisk extraktion och isolering av enzymatisk komponent fran ormgift
US3985618A (en) * 1975-05-02 1976-10-12 Irving Innerfield Method for detection of thrombosis and prethrombosis

Also Published As

Publication number Publication date
IE44735L (en) 1977-10-10
DK158677A (da) 1977-10-11
IE44735B1 (en) 1982-03-10
US4154656A (en) 1979-05-15
NL7703444A (nl) 1977-10-12
GB1519285A (en) 1978-07-26
DE2615844A1 (de) 1977-10-20
BE852758A (fr) 1977-09-22
AT353423B (de) 1979-11-12
LU77089A1 (fr) 1977-08-10
ATA244877A (de) 1979-04-15
FR2361412B1 (fr) 1980-04-04
JPS52125689A (en) 1977-10-21

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Legal Events

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