FR2364654A1 - Composition antibiotique contenant un derive solide de la cephalosporine et un sel de l'acide carbonique - Google Patents
Composition antibiotique contenant un derive solide de la cephalosporine et un sel de l'acide carboniqueInfo
- Publication number
- FR2364654A1 FR2364654A1 FR7726356A FR7726356A FR2364654A1 FR 2364654 A1 FR2364654 A1 FR 2364654A1 FR 7726356 A FR7726356 A FR 7726356A FR 7726356 A FR7726356 A FR 7726356A FR 2364654 A1 FR2364654 A1 FR 2364654A1
- Authority
- FR
- France
- Prior art keywords
- composition containing
- carbonic acid
- antibiotic composition
- cephalosporin
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 239000000243 solution Substances 0.000 abstract 2
- -1 2-imino-4-thiazolin-4-yl Chemical group 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010024769 Local reaction Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000249 desinfective effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Composition antibiotique solide renfermant du dichlorhy-drate de l'acide 7 beta -Ø2-(2-imino-4-thiazolin-4-yl) acétamidoõ-3-Ø1-Ø2-N,N-diméthylamino) éthylõ-1H-tétrazol-5-ylõ thiométhyl-3-céphème-4-carboxylique, ou son hydrate, et un sel de l'acide carbonique pharmaceutiquement acceptable, qui est rapidement transformée en solutions injectables par addition d'un solvant, lesquelles solutions montrent une activité antibactérienne élevée en donnant moins de réactions locales, quand elles sont injectées. Utilisation de ces compositions antibiotiques pour traiter des maladies infectieuses ou bien pour désinfecter les instruments chirurgicaux et les salles d'hôpitaux.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10458276A JPS5329936A (en) | 1976-08-31 | 1976-08-31 | Antibiotic composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2364654A1 true FR2364654A1 (fr) | 1978-04-14 |
| FR2364654B1 FR2364654B1 (fr) | 1981-07-03 |
Family
ID=14384418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7726356A Granted FR2364654A1 (fr) | 1976-08-31 | 1977-08-30 | Composition antibiotique contenant un derive solide de la cephalosporine et un sel de l'acide carbonique |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US4161527A (fr) |
| JP (1) | JPS5329936A (fr) |
| CA (1) | CA1109795A (fr) |
| CH (1) | CH638680A5 (fr) |
| DE (1) | DE2738712A1 (fr) |
| FR (1) | FR2364654A1 (fr) |
| GB (1) | GB1591654A (fr) |
| NL (1) | NL189335C (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0006011A1 (fr) * | 1978-06-02 | 1979-12-12 | Takeda Chemical Industries, Ltd. | Céphalosporines et compositions pharmaceutiques les contenant |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MC1259A1 (fr) * | 1978-05-30 | 1980-01-14 | Hoffmann La Roche | Derives acyles |
| ES8502863A1 (es) * | 1982-09-10 | 1985-02-01 | Glaxo Group Ltd | Un procedimiento para la produccion de un recipiente hermeticamente cerrado que contiene al menos un antibiotico de beta-lactama. |
| JPH0732743Y2 (ja) * | 1984-04-20 | 1995-07-31 | 株式会社河合楽器製作所 | 防音室の床構造 |
| JPS6292670U (fr) * | 1985-12-02 | 1987-06-13 | ||
| US5227157A (en) * | 1986-10-14 | 1993-07-13 | Board Of Regents, The University Of Texas System | Delivery of therapeutic agents |
| IE61679B1 (en) * | 1987-08-10 | 1994-11-16 | Fujisawa Pharmaceutical Co | Water-soluble antibiotic composition and water-soluble salts of new cephem compounds |
| US4933334A (en) * | 1987-12-04 | 1990-06-12 | Takeda Chemical Industries, Ltd. | Antibiotic composition |
| JPH0227569U (fr) * | 1988-08-10 | 1990-02-22 | ||
| JPH0492671U (fr) * | 1990-12-28 | 1992-08-12 | ||
| JPH07215875A (ja) * | 1994-01-27 | 1995-08-15 | Taiyo Yakuhin Kogyo Kk | 安定な塩酸セフォチアム製剤 |
| JP5109918B2 (ja) * | 2001-10-03 | 2012-12-26 | ニプロ株式会社 | 複室容器製剤 |
| WO2004096279A1 (fr) * | 2003-04-28 | 2004-11-11 | Takeda Pharmaceutical Company Limited | Composition pour injection |
| KR20070036088A (ko) * | 2004-06-30 | 2007-04-02 | 디에스엠 아이피 어셋츠 비.브이. | 베타-락탐 항생제를 포함하는 생성물 |
| TW200732292A (en) * | 2006-02-01 | 2007-09-01 | Shell Int Research | A method of treating an aldehyde mixture, use of the treated aldehyde, and an alcohol |
| CA2716872C (fr) | 2008-02-29 | 2015-02-10 | Ferrosan Medical Devices A/S | Dispositif pour la promotion de l'homeostasie et/ou la cicatrisation des plaies |
| CN101569628B (zh) | 2009-06-19 | 2011-05-18 | 山东罗欣药业股份有限公司 | 一种盐酸头孢甲肟组合物粉针及其制备方法 |
| CN104159527B (zh) | 2012-03-06 | 2017-04-12 | 弗罗桑医疗设备公司 | 包含止血糊剂的压力容器 |
| RU2636240C2 (ru) | 2012-06-12 | 2017-11-21 | Ферросан Медикал Дивайсиз А/С | Сухая гемостатическая композиция |
| JP6390873B2 (ja) | 2013-06-21 | 2018-09-19 | フェッローサン メディカル ディバイス エー/エス | 減圧膨張させた乾燥組成物およびそれを保持するためのシリンジ |
| BR112016013322B1 (pt) | 2013-12-11 | 2020-07-21 | Ferrosan Medical Devices A/S | métodos para preparação de uma composição seca e para reconstituir uma composição seca, composição seca, uso de uma composição seca, e, kit |
| BR112017007466B1 (pt) | 2014-10-13 | 2021-03-02 | Ferrosan Medical Devices A/S | método para preparar uma composição seca, método para reconstituir a composição seca, pasta, composição seca, recipiente, kit homeostático, e, uso de uma composição seca |
| RU2705905C2 (ru) | 2014-12-24 | 2019-11-12 | Ферросан Медикал Дивайсиз А/С | Шприц для удерживания и смешивания первого и второго веществ |
| CA2986981A1 (fr) | 2015-07-03 | 2017-01-12 | Ferrosan Medical Devices A/S | Seringue pour melanger deux composants et pour conserver un vide dans une condition de stockage |
| EP4321182A3 (fr) | 2018-05-09 | 2024-05-29 | Ferrosan Medical Devices A/S | Procédé de préparation d'une composition hémostatique |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2035118A1 (fr) * | 1969-03-20 | 1970-12-18 | Pfizer | |
| FR2124499A1 (fr) * | 1971-02-05 | 1972-09-22 | Squibb & Sons Inc | |
| FR2261772A1 (fr) * | 1974-02-22 | 1975-09-19 | Lilly Co Eli |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57873B2 (fr) * | 1973-12-25 | 1982-01-08 |
-
1976
- 1976-08-31 JP JP10458276A patent/JPS5329936A/ja active Granted
-
1977
- 1977-08-27 DE DE19772738712 patent/DE2738712A1/de active Granted
- 1977-08-29 US US05/828,841 patent/US4161527A/en not_active Expired - Lifetime
- 1977-08-30 GB GB36147/77A patent/GB1591654A/en not_active Expired
- 1977-08-30 CA CA285,794A patent/CA1109795A/fr not_active Expired
- 1977-08-30 FR FR7726356A patent/FR2364654A1/fr active Granted
- 1977-08-31 NL NLAANVRAGE7709615,A patent/NL189335C/xx not_active IP Right Cessation
-
1979
- 1979-03-09 US US06/019,185 patent/US4241057A/en not_active Expired - Lifetime
-
1982
- 1982-03-09 CH CH144082A patent/CH638680A5/de not_active IP Right Cessation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2035118A1 (fr) * | 1969-03-20 | 1970-12-18 | Pfizer | |
| FR2124499A1 (fr) * | 1971-02-05 | 1972-09-22 | Squibb & Sons Inc | |
| FR2261772A1 (fr) * | 1974-02-22 | 1975-09-19 | Lilly Co Eli |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0006011A1 (fr) * | 1978-06-02 | 1979-12-12 | Takeda Chemical Industries, Ltd. | Céphalosporines et compositions pharmaceutiques les contenant |
Also Published As
| Publication number | Publication date |
|---|---|
| US4161527A (en) | 1979-07-17 |
| NL189335B (nl) | 1992-10-16 |
| DE2738712A1 (de) | 1978-03-02 |
| FR2364654B1 (fr) | 1981-07-03 |
| JPS5329936A (en) | 1978-03-20 |
| NL189335C (nl) | 1993-03-16 |
| GB1591654A (en) | 1981-06-24 |
| CH638680A5 (de) | 1983-10-14 |
| US4241057A (en) | 1980-12-23 |
| CA1109795A (fr) | 1981-09-29 |
| JPS5636174B2 (fr) | 1981-08-22 |
| DE2738712C2 (fr) | 1988-01-21 |
| NL7709615A (nl) | 1978-03-02 |
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