FR2367775A1 - Derives nouveaux de la kanamycine c actifs contre diverses bacteries resistantes aux medicaments - Google Patents

Derives nouveaux de la kanamycine c actifs contre diverses bacteries resistantes aux medicaments

Info

Publication number
FR2367775A1
FR2367775A1 FR7731107A FR7731107A FR2367775A1 FR 2367775 A1 FR2367775 A1 FR 2367775A1 FR 7731107 A FR7731107 A FR 7731107A FR 7731107 A FR7731107 A FR 7731107A FR 2367775 A1 FR2367775 A1 FR 2367775A1
Authority
FR
France
Prior art keywords
kanamycin
resistant bacteria
new derivatives
active against
against various
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7731107A
Other languages
English (en)
Other versions
FR2367775B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of FR2367775A1 publication Critical patent/FR2367775A1/fr
Application granted granted Critical
Publication of FR2367775B1 publication Critical patent/FR2367775B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

On a préparé de nouveaux dérivés 1-N-(L-4-amino-2-Hydro-xybutyryl) de la kanamycine C, la 3'-désoxykanamycine C et 3', 4'-didésoxykanamycine C qui présente une forte activité antibactérienne à l'égard d'une large variété de bactéries résistantes aux médicaments. Ces nouveaux dérivés sont préparés par réaction de l'acide L-4-amino-2-hydroxybutyrique ou son equivalent fonctionnel avec le groupe 1-amino de la kanamycine C, la 3' -désoxykanamycine C ou la 3', 4'-didésoxykanamycine C.
FR7731107A 1976-10-12 1977-10-11 Derives nouveaux de la kanamycine c actifs contre diverses bacteries resistantes aux medicaments Granted FR2367775A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51121237A JPS6043356B2 (ja) 1976-10-12 1976-10-12 耐性菌に有効なカナマイシンｃ誘導体およびそれらの製造法

Publications (2)

Publication Number Publication Date
FR2367775A1 true FR2367775A1 (fr) 1978-05-12
FR2367775B1 FR2367775B1 (fr) 1980-11-28

Family

ID=14806295

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7731107A Granted FR2367775A1 (fr) 1976-10-12 1977-10-11 Derives nouveaux de la kanamycine c actifs contre diverses bacteries resistantes aux medicaments

Country Status (5)

Country Link
JP (1) JPS6043356B2 (fr)
CA (1) CA1081693A (fr)
DE (1) DE2741431C3 (fr)
FR (1) FR2367775A1 (fr)
GB (1) GB1567560A (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63133258U (fr) * 1987-02-25 1988-08-31
DK157833C (da) * 1988-03-01 1991-04-29 Dansk Transfertryk Fremgangsmaade til laminering af tekstiler

Also Published As

Publication number Publication date
DE2741431C3 (de) 1979-10-25
DE2741431A1 (de) 1978-04-13
JPS6043356B2 (ja) 1985-09-27
DE2741431B2 (de) 1979-03-08
JPS5346940A (en) 1978-04-27
GB1567560A (en) 1980-05-14
FR2367775B1 (fr) 1980-11-28
CA1081693A (fr) 1980-07-15

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Legal Events

Date Code Title Description
ST Notification of lapse