FR2476081B1 - - Google Patents

Info

Publication number: FR2476081B1
Authority: FR; France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR8018670A

Other versions

FR2476081A1 (fr

Inventor

Ronnie Ray Crenshaw

Aldo Antonio Algieri

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Co

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-09-04

Filing date

1980-08-28

Publication date

1985-04-12

1980-08-28 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1981-08-21 Publication of FR2476081A1 publication Critical patent/FR2476081A1/fr

1985-04-12 Application granted granted Critical

1985-04-12 Publication of FR2476081B1 publication Critical patent/FR2476081B1/fr

Status Granted legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/08—1,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

FR8018670A 1979-09-04 1980-08-28 1,2,5-thiadiazole 1-oxydes et 1,2,5-thiadiazole 1,1-dioxydes 3,4 disubstitues, leur procede de preparation et leur application pharmacologique Granted FR2476081A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7251779A	1979-09-04	1979-09-04

Publications (2)

Publication Number	Publication Date
FR2476081A1 FR2476081A1 (fr)	1981-08-21
FR2476081B1 true FR2476081B1 (fr)	1985-04-12

Family

ID=22108102

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FR8018670A Granted FR2476081A1 (fr)	1979-09-04	1980-08-28	1,2,5-thiadiazole 1-oxydes et 1,2,5-thiadiazole 1,1-dioxydes 3,4 disubstitues, leur procede de preparation et leur application pharmacologique
FR8115119A Granted FR2486528A1 (fr)	1979-09-04	1981-08-04	Derives de thiadiazole 1-oxyde

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
FR8115119A Granted FR2486528A1 (fr)	1979-09-04	1981-08-04	Derives de thiadiazole 1-oxyde

Country Status (11)

Country	Link
JP (1)	JPS63211272A (fr)
KR (1)	KR850000759B1 (fr)
AT (1)	AT380019B (fr)
AU (2)	AU541849B2 (fr)
BE (1)	BE885089A (fr)
CS (2)	CS221977B2 (fr)
FR (2)	FR2476081A1 (fr)
GR (1)	GR70020B (fr)
HU (2)	HU205753B (fr)
YU (2)	YU41941B (fr)
ZA (1)	ZA805250B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3175201D1 (en) *	1980-04-30	1986-10-02	Merck & Co Inc	Aminothiadiazoles as gastric secretion inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL22850A (en) *	1964-03-18	1968-12-26	Merck & Co Inc	3-chloro-1,2,5-thiazdiazole-4-carboxylic acid being an intermediate in the preparation of sulfa drugs
CH482712A (de) *	1964-10-01	1969-12-15	Merck & Co Inc	Verfahren zur Herstellung von 3-Amino-1,2,5-thiadiazolen
DE1770152A1 (de) *	1968-04-08	1971-09-30	Lentia Gmbh	Verfahren zur Herstellung von 3-Amino-4-brom-1,2,5-thiadiazol
US3657237A (en) *	1968-05-22	1972-04-18	Frosst & Co Charles E	Process for making 1 2 5-thiadiazoles in the sinister configuration
AT348517B (de) *	1977-01-19	1979-02-26	Chemie Linz Ag	Verfahren zur herstellung von reinem 3-methoxy- 4- (4'-aminobenzolsulfonamido) -1,2,5-thiadiazol
DE3175201D1 (en) *	1980-04-30	1986-10-02	Merck & Co Inc	Aminothiadiazoles as gastric secretion inhibitors

1980
- 1980-08-25 ZA ZA00805250A patent/ZA805250B/xx unknown
- 1980-08-26 GR GR62755A patent/GR70020B/el unknown
- 1980-08-26 YU YU2132/80A patent/YU41941B/xx unknown
- 1980-08-28 FR FR8018670A patent/FR2476081A1/fr active Granted
- 1980-09-01 AU AU61942/80A patent/AU541849B2/en not_active Ceased
- 1980-09-03 HU HU893724A patent/HU205753B/hu not_active IP Right Cessation
- 1980-09-03 HU HU85912A patent/HU201539B/hu not_active IP Right Cessation
- 1980-09-04 BE BE0/201991A patent/BE885089A/fr not_active IP Right Cessation
- 1980-09-04 CS CS806023A patent/CS221977B2/cs unknown
- 1980-09-04 KR KR1019800003492A patent/KR850000759B1/ko not_active Expired
1981
- 1981-08-04 FR FR8115119A patent/FR2486528A1/fr active Granted
- 1981-09-22 CS CS816980A patent/CS246052B2/cs unknown
1983
- 1983-01-18 YU YU00094/83A patent/YU9483A/xx unknown
1984
- 1984-02-27 AT AT0064684A patent/AT380019B/de not_active IP Right Cessation
- 1984-11-13 AU AU35396/84A patent/AU563856B2/en not_active Ceased
1988
- 1988-01-27 JP JP63014800A patent/JPS63211272A/ja active Pending

Also Published As

Publication number	Publication date
ZA805250B (en)	1981-09-30
HUT57755A (en)	1991-12-30
HU205753B (en)	1992-06-29
AT380019B (de)	1986-03-25
YU213280A (en)	1983-06-30
ATA64684A (de)	1985-08-15
KR830003434A (ko)	1983-06-20
JPS63211272A (ja)	1988-09-02
YU41941B (en)	1988-02-29
AU3539684A (en)	1985-03-14
FR2486528B1 (fr)	1984-12-21
AU6194280A (en)	1981-03-12
GR70020B (fr)	1982-07-23
FR2486528A1 (fr)	1982-01-15
FR2476081A1 (fr)	1981-08-21
YU9483A (en)	1983-06-30
AU541849B2 (en)	1985-01-24
HU201539B (en)	1990-11-28
CS221977B2 (en)	1983-04-29
BE885089A (fr)	1981-03-04
CS246052B2 (en)	1986-10-16
KR850000759B1 (ko)	1985-05-25
AU563856B2 (en)	1987-07-23

Legal Events

Date	Code	Title	Description
1996-06-14	ST	Notification of lapse

Publication	Publication Date	Title
FR2446970B1 (fr)	1981-12-04
DE2936318C3 (fr)	1982-03-11
FR2448117B1 (fr)	1982-04-16
FR2449569B1 (fr)	1983-04-01
FR2451912B1 (fr)	1983-12-09
FR2446189B1 (fr)	1981-03-20
FR2448602B1 (fr)	1982-07-09
FR2449367B3 (fr)	1981-12-18
FR2486528B1 (fr)	1984-12-21
FR2449407B1 (fr)	1981-04-30
JPS55121581U (fr)	1980-08-28
JPS55121580U (fr)	1980-08-28
JPS55147467U (fr)	1980-10-23
JPS55147706U (fr)	1980-10-23
JPS5697653U (fr)	1981-08-03
JPS55125608U (fr)	1980-09-05
FR2451319B1 (fr)	1983-06-17
FR2447392B1 (fr)	1982-05-21
FR2449598B1 (fr)	1983-07-08
FR2447057B1 (fr)	1983-02-11
JPS55101256U (fr)	1980-07-15
JPS55147536U (fr)	1980-10-23
JPS55102358U (fr)	1980-07-17
JPS55124109U (fr)	1980-09-03
JPS55102266U (fr)	1980-07-16