FR2685329B1 - Derives de 3(2h)-pyridazinone et procede pour les preparer. - Google Patents

Derives de 3(2h)-pyridazinone et procede pour les preparer.

Info

Publication number
FR2685329B1
FR2685329B1 FR9215297A FR9215297A FR2685329B1 FR 2685329 B1 FR2685329 B1 FR 2685329B1 FR 9215297 A FR9215297 A FR 9215297A FR 9215297 A FR9215297 A FR 9215297A FR 2685329 B1 FR2685329 B1 FR 2685329B1
Authority
FR
France
Prior art keywords
preparing
same
pyridazinone derivatives
pyridazinone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9215297A
Other languages
English (en)
Other versions
FR2685329A1 (fr
Inventor
Peter Matyus
Klara Czako
Ildiko Varga
Andrea Jednakovics
Agnes-Nee-Behr Papp
Ilona Bodi
Andras Rabloczky Gyorgyvarro
Laszlo Jaszlits
Aniko-Nee-Kovacs Miklos
Luca-Nee-Szalay Levay
Gyorgy Schmidt
Marton Fekete
Maria Kurty
Katalin Szemeredi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FR2685329A1 publication Critical patent/FR2685329A1/fr
Application granted granted Critical
Publication of FR2685329B1 publication Critical patent/FR2685329B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FR9215297A 1991-12-20 1992-12-18 Derives de 3(2h)-pyridazinone et procede pour les preparer. Expired - Fee Related FR2685329B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU914057A HU214320B (hu) 1991-12-20 1991-12-20 Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására

Publications (2)

Publication Number Publication Date
FR2685329A1 FR2685329A1 (fr) 1993-06-25
FR2685329B1 true FR2685329B1 (fr) 1994-12-02

Family

ID=10966710

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9215297A Expired - Fee Related FR2685329B1 (fr) 1991-12-20 1992-12-18 Derives de 3(2h)-pyridazinone et procede pour les preparer.

Country Status (22)

Country Link
US (1) US5395934A (fr)
JP (1) JP3165935B2 (fr)
KR (1) KR100234596B1 (fr)
CN (1) CN1088578A (fr)
AT (1) AT403282B (fr)
BE (1) BE1006223A4 (fr)
CA (1) CA2085796C (fr)
CH (1) CH684754A5 (fr)
CZ (1) CZ286039B6 (fr)
DE (1) DE4243381B4 (fr)
DK (1) DK152892A (fr)
ES (1) ES2108595B1 (fr)
FI (1) FI106374B (fr)
FR (1) FR2685329B1 (fr)
GB (1) GB2262526B (fr)
GR (1) GR1002281B (fr)
HU (1) HU214320B (fr)
NL (1) NL194966C (fr)
PL (1) PL172933B1 (fr)
RU (1) RU2130019C1 (fr)
YU (1) YU48973B (fr)
ZA (1) ZA929903B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935945A (en) * 1996-10-31 1999-08-10 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
US5969017A (en) * 1996-10-31 1999-10-19 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
JP2004500314A (ja) 1998-06-05 2004-01-08 エギシュ　ヂョヂセルヂャール　エルテー ３（２ｈ）−ピリダジノン−４−置換アミノ−５−クロロ−誘導体の製法
RU2211217C2 (ru) * 1998-06-05 2003-08-27 Эгиш Дьёдьсердьяр Рт. Способ получения 5-хлор-4-аминозамещенного производного 3(2н)-пиридазинона
ES2162731B1 (es) * 1999-06-04 2003-02-16 Faes Fabrica Espanola De Produ Nuevas arilpiperacilnilalquil-3(2h)-piridacinonas.
WO2001034151A1 (fr) * 1999-11-11 2001-05-17 Fred Hutchinson Cancer Research Center Nouveaux poisons de topoisomerases pour traiter des maladies proliferatives
US7173063B1 (en) 2000-11-10 2007-02-06 Fred Hutchinson Cancer Research Center Topoisomerase poisons for the treatment of proliferative disorders
HUP0103064A3 (en) * 2001-07-26 2005-06-28 Egis Gyogyszergyar Nyilvanosan Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it
HU227237B1 (en) * 2001-09-27 2010-12-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them
AU2003209321A1 (en) * 2002-01-18 2003-07-30 Pharmacia Corporation Substituted pyridazinones as inhibitors of p38
HU227181B1 (en) * 2002-09-11 2010-09-28 Egis Gyogyszergyar Nyilvanosan Use of 5-chloro-4-[3-[n-[2-(3,4-dimethoxyphenyl)ethyl)]-n-methylamino]-propylamino]-3-(2h)-pyridazinone for producing pharmaceutical compositions having metabolic modulator effect
WO2011062437A2 (fr) * 2009-11-20 2011-05-26 에스케이케미칼주식회사 Antagonistes des récepteurs de l'hormone de libération des gonadotrophines, leurs procédés de production et composition pharmaceutique les contenant
JP2013518907A (ja) * 2010-02-08 2013-05-23 アラーガン インコーポレイテッド カンナビノイド−２作動薬として有用なピリダジン誘導体
FR2969606B1 (fr) * 2010-12-22 2013-01-11 Pf Medicament Derives de diarylpyridazinones, leur preparation et leur application en therapeutique humaine
RU2455004C1 (ru) * 2011-04-01 2012-07-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ФГБОУ ВПО "ЯГТУ") Способ получения сульфохлоридов ряда 6-арилпиридазин-3(2н)-онов

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1285235A (fr) * 1960-01-21 1962-02-23 Ciba Geigy Procédé de préparation de nouvelles diazines, notamment de 1-aryl-3-r-5-r'pyridazones-(6) dans lesquelles r représente un hydroxyle aliphatiquement éthérifié et r' représente un groupe n-(beta-aryl-éthyl)-pipérazino
FR2124164A1 (en) 1971-02-10 1972-09-22 Ferlux Phenyl pyridazonyl piperazines - analgesics hypotensives sedatives and antibacterials
US4088764A (en) * 1973-12-27 1978-05-09 Cassella Farbwerke Mainkur Aktiengesellschaft Pharmaceutically active derivatives of 1-phenoxy-3-amino-propan-2-ol
DE3048487A1 (de) * 1980-12-22 1982-07-29 Cassella Ag, 6000 Frankfurt Basisch substituierte pyridazine, ihre herstellung und ihre verwendung
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
US4892947A (en) * 1985-04-27 1990-01-09 Nissan Chemical Industries Ltd. 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it
MY104343A (en) * 1987-11-23 1994-03-31 Janssen Pharmaceutica Nv Novel pyridizinamine deravatives
US4992433A (en) * 1987-11-23 1991-02-12 Janssen Pharmaceutica N.V. Novel pyridazinamine derivatives
US4992243A (en) * 1988-03-17 1991-02-12 Fedin Marat A Method of sterilizing anthers
IE62890B1 (en) * 1988-12-06 1995-03-08 Hafslund Nycomed Pharma New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
DE3902316A1 (de) * 1989-01-26 1990-08-02 Lentia Gmbh Neue piperazinylalkyl-3(2h)-pyridazinone, verfahren zu ihrer herstellung und ihre verwendung als blutdrucksenkende mittel

Also Published As

Publication number Publication date
DE4243381B4 (de) 2005-07-28
HU914057D0 (en) 1992-03-30
ES2108595A1 (es) 1997-12-16
CA2085796A1 (fr) 1993-06-21
ES2108595B1 (es) 1998-08-16
ZA929903B (en) 1993-06-24
GB2262526A (en) 1993-06-23
PL172933B1 (pl) 1997-12-31
CA2085796C (fr) 2000-08-08
AU3031792A (en) 1993-06-24
NL194966B (nl) 2003-05-01
FR2685329A1 (fr) 1993-06-25
CN1088578A (zh) 1994-06-29
FI106374B (fi) 2001-01-31
HUT62865A (en) 1993-06-28
FI925807A0 (fi) 1992-12-21
GR1002281B (el) 1996-05-02
BE1006223A4 (fr) 1994-06-14
YU109292A (sr) 1996-01-09
PL297070A1 (en) 1994-03-07
CZ286039B6 (cs) 1999-12-15
NL194966C (nl) 2003-09-02
GB2262526B (en) 1995-07-26
NL9202210A (nl) 1993-07-16
GB9226601D0 (en) 1993-02-17
DK152892A (da) 1993-06-21
HU214320B (hu) 1998-03-02
DE4243381A1 (fr) 1993-06-24
CZ380992A3 (en) 1993-09-15
YU48973B (sh) 2003-02-28
ATA253592A (de) 1997-05-15
RU2130019C1 (ru) 1999-05-10
AU652304B2 (en) 1994-08-18
CH684754A5 (de) 1994-12-15
FI925807A7 (fi) 1993-06-21
JP3165935B2 (ja) 2001-05-14
US5395934A (en) 1995-03-07
KR100234596B1 (ko) 1999-12-15
JPH05255276A (ja) 1993-10-05
GR920100570A (el) 1993-08-31
AT403282B (de) 1997-12-29
DK152892D0 (da) 1992-12-21

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20060831