ATA253592A - 3(2h)-pyridazinon-derivate und verfahren zu ihrer herstellung - Google Patents

3(2h)-pyridazinon-derivate und verfahren zu ihrer herstellung

Info

Publication number
ATA253592A
ATA253592A AT0253592A AT253592A ATA253592A AT A253592 A ATA253592 A AT A253592A AT 0253592 A AT0253592 A AT 0253592A AT 253592 A AT253592 A AT 253592A AT A253592 A ATA253592 A AT A253592A
Authority
AT
Austria
Prior art keywords
production
pyridazinone derivatives
pyridazinone
derivatives
Prior art date
Application number
AT0253592A
Other languages
English (en)
Other versions
AT403282B (de
Inventor
Peter Dr Ing Matyus
Klara Czako
Ildiko Ing Varga
Andrea Jednakovics
Agnes Dr Ing Papp
Ilona Dr Bodi
Gyoergy Dr Rabloczky
Andras Dr Varro
Laszlo Dr Jaszlits
Aniko Dr Miklos
Luca Levay
Gyoergy Schmidt
Marton Dr Fekete
Maria Kuerthy
Katalin Dr Szemeredi
Erzsebet Dr Ing Zara
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ATA253592A publication Critical patent/ATA253592A/de
Application granted granted Critical
Publication of AT403282B publication Critical patent/AT403282B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT0253592A 1991-12-20 1992-12-21 3(2h)-pyridazinon-derivate und verfahren zu ihrer herstellung AT403282B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU914057A HU214320B (hu) 1991-12-20 1991-12-20 Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására

Publications (2)

Publication Number Publication Date
ATA253592A true ATA253592A (de) 1997-05-15
AT403282B AT403282B (de) 1997-12-29

Family

ID=10966710

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0253592A AT403282B (de) 1991-12-20 1992-12-21 3(2h)-pyridazinon-derivate und verfahren zu ihrer herstellung

Country Status (22)

Country Link
US (1) US5395934A (de)
JP (1) JP3165935B2 (de)
KR (1) KR100234596B1 (de)
CN (1) CN1088578A (de)
AT (1) AT403282B (de)
BE (1) BE1006223A4 (de)
CA (1) CA2085796C (de)
CH (1) CH684754A5 (de)
CZ (1) CZ286039B6 (de)
DE (1) DE4243381B4 (de)
DK (1) DK152892A (de)
ES (1) ES2108595B1 (de)
FI (1) FI106374B (de)
FR (1) FR2685329B1 (de)
GB (1) GB2262526B (de)
GR (1) GR1002281B (de)
HU (1) HU214320B (de)
NL (1) NL194966C (de)
PL (1) PL172933B1 (de)
RU (1) RU2130019C1 (de)
YU (1) YU48973B (de)
ZA (1) ZA929903B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935945A (en) * 1996-10-31 1999-08-10 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
US5969017A (en) * 1996-10-31 1999-10-19 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
JP2004500314A (ja) 1998-06-05 2004-01-08 エギシュ　ヂョヂセルヂャール　エルテー ３（２ｈ）−ピリダジノン−４−置換アミノ−５−クロロ−誘導体の製法
RU2211217C2 (ru) * 1998-06-05 2003-08-27 Эгиш Дьёдьсердьяр Рт. Способ получения 5-хлор-4-аминозамещенного производного 3(2н)-пиридазинона
ES2162731B1 (es) * 1999-06-04 2003-02-16 Faes Fabrica Espanola De Produ Nuevas arilpiperacilnilalquil-3(2h)-piridacinonas.
WO2001034151A1 (en) * 1999-11-11 2001-05-17 Fred Hutchinson Cancer Research Center Novel topoisomerase poisons for the treatment of proliferative disorders
US7173063B1 (en) 2000-11-10 2007-02-06 Fred Hutchinson Cancer Research Center Topoisomerase poisons for the treatment of proliferative disorders
HUP0103064A3 (en) * 2001-07-26 2005-06-28 Egis Gyogyszergyar Nyilvanosan Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it
HU227237B1 (en) * 2001-09-27 2010-12-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them
AU2003209321A1 (en) * 2002-01-18 2003-07-30 Pharmacia Corporation Substituted pyridazinones as inhibitors of p38
HU227181B1 (en) * 2002-09-11 2010-09-28 Egis Gyogyszergyar Nyilvanosan Use of 5-chloro-4-[3-[n-[2-(3,4-dimethoxyphenyl)ethyl)]-n-methylamino]-propylamino]-3-(2h)-pyridazinone for producing pharmaceutical compositions having metabolic modulator effect
WO2011062437A2 (ko) * 2009-11-20 2011-05-26 에스케이케미칼주식회사 고나도트로핀 방출 호르몬 수용체 길항제, 이의 제조방법 및 이를 함유하는 약제학적 조성물
JP2013518907A (ja) * 2010-02-08 2013-05-23 アラーガン インコーポレイテッド カンナビノイド−２作動薬として有用なピリダジン誘導体
FR2969606B1 (fr) * 2010-12-22 2013-01-11 Pf Medicament Derives de diarylpyridazinones, leur preparation et leur application en therapeutique humaine
RU2455004C1 (ru) * 2011-04-01 2012-07-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ФГБОУ ВПО "ЯГТУ") Способ получения сульфохлоридов ряда 6-арилпиридазин-3(2н)-онов

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1285235A (fr) * 1960-01-21 1962-02-23 Ciba Geigy Procédé de préparation de nouvelles diazines, notamment de 1-aryl-3-r-5-r'pyridazones-(6) dans lesquelles r représente un hydroxyle aliphatiquement éthérifié et r' représente un groupe n-(beta-aryl-éthyl)-pipérazino
FR2124164A1 (en) 1971-02-10 1972-09-22 Ferlux Phenyl pyridazonyl piperazines - analgesics hypotensives sedatives and antibacterials
US4088764A (en) * 1973-12-27 1978-05-09 Cassella Farbwerke Mainkur Aktiengesellschaft Pharmaceutically active derivatives of 1-phenoxy-3-amino-propan-2-ol
DE3048487A1 (de) * 1980-12-22 1982-07-29 Cassella Ag, 6000 Frankfurt Basisch substituierte pyridazine, ihre herstellung und ihre verwendung
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
US4892947A (en) * 1985-04-27 1990-01-09 Nissan Chemical Industries Ltd. 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it
MY104343A (en) * 1987-11-23 1994-03-31 Janssen Pharmaceutica Nv Novel pyridizinamine deravatives
US4992433A (en) * 1987-11-23 1991-02-12 Janssen Pharmaceutica N.V. Novel pyridazinamine derivatives
US4992243A (en) * 1988-03-17 1991-02-12 Fedin Marat A Method of sterilizing anthers
IE62890B1 (en) * 1988-12-06 1995-03-08 Hafslund Nycomed Pharma New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
DE3902316A1 (de) * 1989-01-26 1990-08-02 Lentia Gmbh Neue piperazinylalkyl-3(2h)-pyridazinone, verfahren zu ihrer herstellung und ihre verwendung als blutdrucksenkende mittel

Also Published As

Publication number Publication date
DE4243381B4 (de) 2005-07-28
HU914057D0 (en) 1992-03-30
ES2108595A1 (es) 1997-12-16
CA2085796A1 (en) 1993-06-21
ES2108595B1 (es) 1998-08-16
ZA929903B (en) 1993-06-24
GB2262526A (en) 1993-06-23
PL172933B1 (pl) 1997-12-31
CA2085796C (en) 2000-08-08
AU3031792A (en) 1993-06-24
NL194966B (nl) 2003-05-01
FR2685329A1 (fr) 1993-06-25
CN1088578A (zh) 1994-06-29
FI106374B (fi) 2001-01-31
HUT62865A (en) 1993-06-28
FI925807A0 (fi) 1992-12-21
GR1002281B (el) 1996-05-02
BE1006223A4 (fr) 1994-06-14
YU109292A (sr) 1996-01-09
PL297070A1 (en) 1994-03-07
CZ286039B6 (cs) 1999-12-15
FR2685329B1 (fr) 1994-12-02
NL194966C (nl) 2003-09-02
GB2262526B (en) 1995-07-26
NL9202210A (nl) 1993-07-16
GB9226601D0 (en) 1993-02-17
DK152892A (da) 1993-06-21
HU214320B (hu) 1998-03-02
DE4243381A1 (de) 1993-06-24
CZ380992A3 (en) 1993-09-15
YU48973B (sh) 2003-02-28
RU2130019C1 (ru) 1999-05-10
AU652304B2 (en) 1994-08-18
CH684754A5 (de) 1994-12-15
FI925807A7 (fi) 1993-06-21
JP3165935B2 (ja) 2001-05-14
US5395934A (en) 1995-03-07
KR100234596B1 (ko) 1999-12-15
JPH05255276A (ja) 1993-10-05
GR920100570A (el) 1993-08-31
AT403282B (de) 1997-12-29
DK152892D0 (da) 1992-12-21

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