FR2717823B1 - Virus recombinants, préparation et utilisation en thérapie génique. - Google Patents

Virus recombinants, préparation et utilisation en thérapie génique.

Info

Publication number
FR2717823B1
FR2717823B1 FR9403411A FR9403411A FR2717823B1 FR 2717823 B1 FR2717823 B1 FR 2717823B1 FR 9403411 A FR9403411 A FR 9403411A FR 9403411 A FR9403411 A FR 9403411A FR 2717823 B1 FR2717823 B1 FR 2717823B1
Authority
FR
France
Prior art keywords
preparation
gene therapy
recombinant viruses
viruses
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9403411A
Other languages
English (en)
Other versions
FR2717823A1 (fr
Inventor
Jean Francois Julien
Jean-Jacques Robert
Marie-Claude Geoffroy
Michel Perricaudet
Emmanuelle Vigne
Jacques Mallet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut Gustave Roussy (IGR)
Aventis Pharma SA
Original Assignee
Centre National de la Recherche Scientifique CNRS
Rhone Poulenc Rorer SA
Institut Gustave Roussy (IGR)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Rhone Poulenc Rorer SA, Institut Gustave Roussy (IGR) filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR9403411A priority Critical patent/FR2717823B1/fr
Priority to ZA952286A priority patent/ZA952286B/xx
Priority to IL11305295A priority patent/IL113052A0/xx
Priority to FI963755A priority patent/FI963755L/fi
Priority to AU21406/95A priority patent/AU2140695A/en
Priority to DE69534873T priority patent/DE69534873T2/de
Priority to EP95914389A priority patent/EP0752003B1/fr
Priority to EP06004834A priority patent/EP1681354A3/fr
Priority to CA002184297A priority patent/CA2184297C/fr
Priority to AT95914389T priority patent/ATE320502T1/de
Priority to KR1019960705265A priority patent/KR100403893B1/ko
Priority to MX9604026A priority patent/MX9604026A/es
Priority to PCT/FR1995/000342 priority patent/WO1995025805A1/fr
Priority to US08/704,583 priority patent/US20020028212A1/en
Priority to JP7524435A priority patent/JPH09511394A/ja
Publication of FR2717823A1 publication Critical patent/FR2717823A1/fr
Application granted granted Critical
Publication of FR2717823B1 publication Critical patent/FR2717823B1/fr
Priority to NO963806A priority patent/NO963806D0/no
Priority to AU42334/99A priority patent/AU4233499A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9403411A 1994-03-23 1994-03-23 Virus recombinants, préparation et utilisation en thérapie génique. Expired - Lifetime FR2717823B1 (fr)

Priority Applications (17)

Application Number Priority Date Filing Date Title
FR9403411A FR2717823B1 (fr) 1994-03-23 1994-03-23 Virus recombinants, préparation et utilisation en thérapie génique.
IL11305295A IL113052A0 (en) 1994-03-23 1995-03-20 Recombinant viruses, their preparation and their use in gene therapy
ZA952286A ZA952286B (en) 1994-03-23 1995-03-20 Recombinant viruses their preparation and their use in gene therapy
PCT/FR1995/000342 WO1995025805A1 (fr) 1994-03-23 1995-03-21 Virus recombinants codant pour une activite glutamate decarboxylase (gad)
DE69534873T DE69534873T2 (de) 1994-03-23 1995-03-21 Für eine glutamat-dekarboxylase-aktivität kodierende rekombinierende viren
EP95914389A EP0752003B1 (fr) 1994-03-23 1995-03-21 Virus recombinants codant pour une activite glutamate decarboxylase (gad)
EP06004834A EP1681354A3 (fr) 1994-03-23 1995-03-21 Virus recombinants codant pour une activité glutamate décarboxylase (GAD)
CA002184297A CA2184297C (fr) 1994-03-23 1995-03-21 Virus recombinants codant pour une activite glutamate decarboxylase (gad)
FI963755A FI963755L (fi) 1994-03-23 1995-03-21 Glutamaatti-dekarboksylaasi-aktiivisuutta (GAD-aktiivisuutta) koodaavat yhdistelmä-DNA-tekniset virukset
KR1019960705265A KR100403893B1 (ko) 1994-03-23 1995-03-21 글루타메이트 디 카르복실라제(gad) 활성을 암호화하는 재조합바이러스
MX9604026A MX9604026A (es) 1994-03-23 1995-03-21 Virus recombinantes que codifican para una actividad de glutamato-descarboxilasa (gad).
AU21406/95A AU2140695A (en) 1994-03-23 1995-03-21 Recombinant viruses coding for a glutamate decarboxylase (gad) activity
US08/704,583 US20020028212A1 (en) 1994-03-23 1995-03-21 Recombinant viruses coding for a glutamate decarboxylase (gad) activity
JP7524435A JPH09511394A (ja) 1994-03-23 1995-03-21 グルタミン酸デカルボキシラーゼ（ｇａｄ）活性をコードする組換えウイルス
AT95914389T ATE320502T1 (de) 1994-03-23 1995-03-21 Für eine glutamat-dekarboxylase-aktivität kodierende rekombinierende viren
NO963806A NO963806D0 (no) 1994-03-23 1996-09-11 Rekombinante viruser som koder for en glutamat-dekarboksylase (GAD)aktivitet
AU42334/99A AU4233499A (en) 1994-03-23 1999-07-28 Recombinant viruses coding for a glutamate decarboxylase (GAD) activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403411A FR2717823B1 (fr) 1994-03-23 1994-03-23 Virus recombinants, préparation et utilisation en thérapie génique.

Publications (2)

Publication Number Publication Date
FR2717823A1 FR2717823A1 (fr) 1995-09-29
FR2717823B1 true FR2717823B1 (fr) 1996-04-26

Family

ID=9461346

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9403411A Expired - Lifetime FR2717823B1 (fr) 1994-03-23 1994-03-23 Virus recombinants, préparation et utilisation en thérapie génique.

Country Status (2)

Country Link
FR (1) FR2717823B1 (fr)
ZA (1) ZA952286B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102154345B (zh) * 2011-01-18 2012-10-10 江南大学 谷氨酸脱羧酶基因及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270452A (en) * 1988-11-28 1993-12-14 Rhone-Poulenc Rorer Pharmaceuticals Inc. Pure glia maturation factor
JP2814529B2 (ja) * 1989-03-16 1998-10-22 味の素株式会社 虚血性脳障害治療薬
US6682906B1 (en) * 1990-09-21 2004-01-27 The Regents Of The University Of California Cloned glutamic acid decarboxylase
FR2688514A1 (fr) * 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
JPH08501686A (ja) * 1992-09-25 1996-02-27 ローン−プーラン・ロレ・ソシエテ・アノニム 中枢神経系、特に脳における細胞への外来遺伝子の転移のためのアデノウィルスベクター
FR2702152B1 (fr) * 1993-03-03 1995-05-24 Inst Nat Sante Rech Med Virus recombinants et leur utilisation en thérapie génique.

Also Published As

Publication number Publication date
FR2717823A1 (fr) 1995-09-29
ZA952286B (en) 1996-01-09

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