FR2766484B1 - Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse - Google Patents

Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse

Info

Publication number
FR2766484B1
FR2766484B1 FR9709477A FR9709477A FR2766484B1 FR 2766484 B1 FR2766484 B1 FR 2766484B1 FR 9709477 A FR9709477 A FR 9709477A FR 9709477 A FR9709477 A FR 9709477A FR 2766484 B1 FR2766484 B1 FR 2766484B1
Authority
FR
France
Prior art keywords
motority
benzamide derivatives
low gastrointestinal
stimulating
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9709477A
Other languages
English (en)
Other versions
FR2766484A1 (fr
Inventor
Christian Jeanpetit
Helene Christinaki
Olivier Boucheix
Thierry Bouyssou
Serge Biosa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Jacques Logeais SA
Original Assignee
Laboratoires Jacques Logeais SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Jacques Logeais SA filed Critical Laboratoires Jacques Logeais SA
Priority to FR9709477A priority Critical patent/FR2766484B1/fr
Priority to TNTNSN98138A priority patent/TNSN98138A1/fr
Priority to ZA986633A priority patent/ZA986633B/xx
Priority to AU88678/98A priority patent/AU8867898A/en
Priority to CO98042280A priority patent/CO4990994A1/es
Priority to ARP980103645A priority patent/AR014900A1/es
Priority to EP98940329A priority patent/EP0998458A1/fr
Priority to PCT/FR1998/001640 priority patent/WO1999005106A1/fr
Publication of FR2766484A1 publication Critical patent/FR2766484A1/fr
Application granted granted Critical
Publication of FR2766484B1 publication Critical patent/FR2766484B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR9709477A 1997-07-25 1997-07-25 Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse Expired - Fee Related FR2766484B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR9709477A FR2766484B1 (fr) 1997-07-25 1997-07-25 Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse
TNTNSN98138A TNSN98138A1 (fr) 1997-07-25 1998-07-15 Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse
AU88678/98A AU8867898A (en) 1997-07-25 1998-07-24 Novel benzamide derivatives stimulating high and low gastrointestinal motricity
CO98042280A CO4990994A1 (es) 1997-07-25 1998-07-24 Nuevos derivados de benzamidas estimulantes de la motricidad gstrointestinal alta y baja
ZA986633A ZA986633B (en) 1997-07-25 1998-07-24 Benzamide derivatives which stimulate upper and lower gastrointestinal motoricity
ARP980103645A AR014900A1 (es) 1997-07-25 1998-07-24 Compuestos de n-alquilbenzamidas-1-piperidinil-4-sustituidas, composicion farmaceutica que los comprende y su uso
EP98940329A EP0998458A1 (fr) 1997-07-25 1998-07-24 Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse
PCT/FR1998/001640 WO1999005106A1 (fr) 1997-07-25 1998-07-24 Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9709477A FR2766484B1 (fr) 1997-07-25 1997-07-25 Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse

Publications (2)

Publication Number Publication Date
FR2766484A1 FR2766484A1 (fr) 1999-01-29
FR2766484B1 true FR2766484B1 (fr) 1999-09-17

Family

ID=9509623

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9709477A Expired - Fee Related FR2766484B1 (fr) 1997-07-25 1997-07-25 Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse

Country Status (8)

Country Link
EP (1) EP0998458A1 (fr)
AR (1) AR014900A1 (fr)
AU (1) AU8867898A (fr)
CO (1) CO4990994A1 (fr)
FR (1) FR2766484B1 (fr)
TN (1) TNSN98138A1 (fr)
WO (1) WO1999005106A1 (fr)
ZA (1) ZA986633B (fr)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE620543A (fr) *
GB1015921A (en) * 1961-10-06 1966-01-05 Benger Lab Ltd Benzamides
AR216043A1 (es) * 1974-03-21 1979-11-30 Anphar Sa Procedimiento para la preparacion de 1-derivados de benzoilamino-4-piperidina y sus sales fisiologicamente aceptables
EP0222533A1 (fr) * 1985-10-25 1987-05-20 The Upjohn Company Cis-N-[(2-aminocycloaliphatique)-benzèneacétamide et -benzamides anticonvulsifs
FR2674849B1 (fr) * 1991-04-02 1994-12-23 Logeais Labor Jacques Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique.
CA2116024A1 (fr) * 1991-08-20 1993-03-04 Francis David King Antagonistes des recepteurs 5-ht4
AU2075295A (en) * 1994-03-14 1995-10-03 Sanofi Use of 4-amino-5-chloro-2-methoxybenzoic esters as 5-ht4 agonists
FR2735693B1 (fr) * 1995-06-23 1997-09-26 Logeais Labor Jacques Nouvelles applications therapeutiques de n-cyclohexyl benzamides

Also Published As

Publication number Publication date
CO4990994A1 (es) 2000-12-26
TNSN98138A1 (fr) 2005-03-15
EP0998458A1 (fr) 2000-05-10
AU8867898A (en) 1999-02-16
FR2766484A1 (fr) 1999-01-29
WO1999005106A1 (fr) 1999-02-04
WO1999005106A8 (fr) 1999-04-15
ZA986633B (en) 1999-06-15
AR014900A1 (es) 2001-04-11

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Legal Events

Date Code Title Description
ST Notification of lapse