AR014900A1 - Compuestos de n-alquilbenzamidas-1-piperidinil-4-sustituidas, composicion farmaceutica que los comprende y su uso - Google Patents
Compuestos de n-alquilbenzamidas-1-piperidinil-4-sustituidas, composicion farmaceutica que los comprende y su usoInfo
- Publication number
- AR014900A1 AR014900A1 ARP980103645A ARP980103645A AR014900A1 AR 014900 A1 AR014900 A1 AR 014900A1 AR P980103645 A ARP980103645 A AR P980103645A AR P980103645 A ARP980103645 A AR P980103645A AR 014900 A1 AR014900 A1 AR 014900A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- alkyl group
- day
- colic
- linear
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Chemical class 0.000 title abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 5
- 208000004998 Abdominal Pain Diseases 0.000 abstract 3
- 208000002881 Colic Diseases 0.000 abstract 3
- 230000001684 chronic effect Effects 0.000 abstract 3
- 206010010774 Constipation Diseases 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000004064 dysfunction Effects 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 208000000289 Esophageal Achalasia Diseases 0.000 abstract 1
- 206010021518 Impaired gastric emptying Diseases 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 206010030136 Oesophageal achalasia Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 201000000621 achalasia Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 230000000112 colonic effect Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 201000006549 dyspepsia Diseases 0.000 abstract 1
- 208000021302 gastroesophageal reflux disease Diseases 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 208000001288 gastroparesis Diseases 0.000 abstract 1
- 208000003243 intestinal obstruction Diseases 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 210000003750 lower gastrointestinal tract Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000001052 transient effect Effects 0.000 abstract 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9709477A FR2766484B1 (fr) | 1997-07-25 | 1997-07-25 | Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR014900A1 true AR014900A1 (es) | 2001-04-11 |
Family
ID=9509623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980103645A AR014900A1 (es) | 1997-07-25 | 1998-07-24 | Compuestos de n-alquilbenzamidas-1-piperidinil-4-sustituidas, composicion farmaceutica que los comprende y su uso |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0998458A1 (fr) |
| AR (1) | AR014900A1 (fr) |
| AU (1) | AU8867898A (fr) |
| CO (1) | CO4990994A1 (fr) |
| FR (1) | FR2766484B1 (fr) |
| TN (1) | TNSN98138A1 (fr) |
| WO (1) | WO1999005106A1 (fr) |
| ZA (1) | ZA986633B (fr) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE620543A (fr) * | ||||
| GB1015921A (en) * | 1961-10-06 | 1966-01-05 | Benger Lab Ltd | Benzamides |
| AR216043A1 (es) * | 1974-03-21 | 1979-11-30 | Anphar Sa | Procedimiento para la preparacion de 1-derivados de benzoilamino-4-piperidina y sus sales fisiologicamente aceptables |
| EP0222533A1 (fr) * | 1985-10-25 | 1987-05-20 | The Upjohn Company | Cis-N-[(2-aminocycloaliphatique)-benzèneacétamide et -benzamides anticonvulsifs |
| FR2674849B1 (fr) * | 1991-04-02 | 1994-12-23 | Logeais Labor Jacques | Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique. |
| CA2116024A1 (fr) * | 1991-08-20 | 1993-03-04 | Francis David King | Antagonistes des recepteurs 5-ht4 |
| AU2075295A (en) * | 1994-03-14 | 1995-10-03 | Sanofi | Use of 4-amino-5-chloro-2-methoxybenzoic esters as 5-ht4 agonists |
| FR2735693B1 (fr) * | 1995-06-23 | 1997-09-26 | Logeais Labor Jacques | Nouvelles applications therapeutiques de n-cyclohexyl benzamides |
-
1997
- 1997-07-25 FR FR9709477A patent/FR2766484B1/fr not_active Expired - Fee Related
-
1998
- 1998-07-15 TN TNTNSN98138A patent/TNSN98138A1/fr unknown
- 1998-07-24 EP EP98940329A patent/EP0998458A1/fr not_active Withdrawn
- 1998-07-24 WO PCT/FR1998/001640 patent/WO1999005106A1/fr not_active Ceased
- 1998-07-24 ZA ZA986633A patent/ZA986633B/xx unknown
- 1998-07-24 AR ARP980103645A patent/AR014900A1/es unknown
- 1998-07-24 CO CO98042280A patent/CO4990994A1/es unknown
- 1998-07-24 AU AU88678/98A patent/AU8867898A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| FR2766484B1 (fr) | 1999-09-17 |
| CO4990994A1 (es) | 2000-12-26 |
| TNSN98138A1 (fr) | 2005-03-15 |
| EP0998458A1 (fr) | 2000-05-10 |
| AU8867898A (en) | 1999-02-16 |
| FR2766484A1 (fr) | 1999-01-29 |
| WO1999005106A1 (fr) | 1999-02-04 |
| WO1999005106A8 (fr) | 1999-04-15 |
| ZA986633B (en) | 1999-06-15 |
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