FR75178E - - Google Patents
Info
- Publication number
- FR75178E FR75178E FR75178DE FR75178E FR 75178 E FR75178 E FR 75178E FR 75178D E FR75178D E FR 75178DE FR 75178 E FR75178 E FR 75178E
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657154—Cyclic esteramides of oxyacids of phosphorus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEA26234A DE1054997B (de) | 1956-12-20 | 1956-12-20 | Verfahren zur Herstellung von cyclischen Thiophosphorsaeure-esteramiden |
| DEA24298A DE1057119B (de) | 1956-12-20 | 1957-12-04 | Verfahren zur Herstellung von cyclischen Phosphorsaeure-esteramiden |
| DEA28444A DE1116672B (de) | 1956-12-20 | 1957-12-04 | Verfahren zur Herstellung von cyclischen Phosphorsaeure- und Thiophosphorsaeureesteramiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR75178E true FR75178E (fr) | 1961-09-08 |
Family
ID=27208860
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR75178D Expired FR75178E (fr) | 1956-12-20 | ||
| FR731011A Expired FR1246708A (fr) | 1956-12-20 | 1957-02-04 | Procédé de préparation d'esteramides phosphoriques cycliques |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR731011A Expired FR1246708A (fr) | 1956-12-20 | 1957-02-04 | Procédé de préparation d'esteramides phosphoriques cycliques |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US3018302A (fr) |
| BE (2) | BE554888A (fr) |
| CH (3) | CH361279A (fr) |
| DE (3) | DE1054997B (fr) |
| FR (2) | FR1246708A (fr) |
| GB (2) | GB812651A (fr) |
| NL (3) | NL99649C (fr) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270093A (en) * | 1963-04-19 | 1966-08-30 | Tenneco Chem | Omicron, omicron-neopentylene-nu-diethylphosphoroamidothioate |
| US3286001A (en) * | 1963-06-07 | 1966-11-15 | Continental Oil Co | Reaction products of organophosphorus monohalides with mercaptoalkylamines |
| US3335129A (en) * | 1963-11-21 | 1967-08-08 | Wyandotte Chemicals Corp | Phosphoramidates |
| DE2110333A1 (de) * | 1971-03-04 | 1972-09-14 | Audi Nsu Auto Union Ag | Kreiskolben-Brennkraftmaschine |
| PL100390B1 (pl) | 1975-10-06 | 1978-09-30 | Sposob wytwarzania 2-tlenku-2-/bis/2-chloroetylo/-amino/-1-/okso-3-aza-2-fosfacykloheksanu/cyklofosfamidu/o czynnosci optycznej | |
| DE3132221A1 (de) * | 1981-08-14 | 1983-05-19 | Behringwerke Ag, 3550 Marburg | Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung |
| DE3133077A1 (de) * | 1981-08-21 | 1983-03-10 | Henkel KGaA, 4000 Düsseldorf | Neue cytostatisch wirksame epoxidgruppen tragende 1,3,2-oxazaphosphorin-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung in pharmazeutischen zubereitungen |
| US4537883A (en) * | 1982-11-12 | 1985-08-27 | Mead Johnson & Company | Lyophilized cyclophosphamide |
| US5227374A (en) * | 1982-11-12 | 1993-07-13 | Mead Johnson & Company | Lyophilized cyclophosphamide |
| US4659699A (en) * | 1983-08-22 | 1987-04-21 | Cetus-Ben Venue Therapeutics | Process for freeze drying cyclophosphamide |
| US4879286A (en) * | 1987-01-28 | 1989-11-07 | Lyphomed, Inc. | Cyclophosphamide |
| IT1251472B (it) * | 1991-09-12 | 1995-05-15 | Boehringer Mannheim Italia | Ossaazafosforine utili come agenti antitumorali, un processo per la loro preparazione e composizioni farmaceutiche che le contengono |
| DE19739159C1 (de) * | 1997-09-06 | 1999-01-28 | Asta Medica Ag | Verfahren zur Herstellung von Oxazaphosphorin-2-aminen |
| US6312662B1 (en) * | 1998-03-06 | 2001-11-06 | Metabasis Therapeutics, Inc. | Prodrugs phosphorus-containing compounds |
| JP4741725B2 (ja) | 1998-03-06 | 2011-08-10 | メタベイシス・セラピューティクス・インコーポレーテッド | リン含有化合物のための新規なプロドラッグ |
| HK1043796B (en) * | 1999-03-05 | 2007-02-23 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing prodrugs |
| US7205404B1 (en) * | 1999-03-05 | 2007-04-17 | Metabasis Therapeutics, Inc. | Phosphorus-containing prodrugs |
| US6752981B1 (en) | 1999-09-08 | 2004-06-22 | Metabasis Therapeutics, Inc. | Prodrugs for liver specific drug delivery |
| US7829084B2 (en) | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| US7214668B2 (en) * | 2002-05-13 | 2007-05-08 | Metabasis Therapeutics, Inc. | Phosphonic acid based prodrugs of PMEA and its analogues |
| AU2003235501A1 (en) * | 2002-05-13 | 2003-11-11 | Metabasis Therapeutics, Inc. | PMEA and PMPA cyclic producing synthesis |
| BR0315795A (pt) | 2002-10-31 | 2005-09-13 | Metabasis Therapeutics Inc | Pró-medicamentos de monofosfato de citarabina |
| US20050182252A1 (en) * | 2004-02-13 | 2005-08-18 | Reddy K. R. | Novel 2'-C-methyl nucleoside derivatives |
| CN1964967B (zh) * | 2004-06-08 | 2014-04-16 | 症变治疗公司 | 路易斯酸介导的环状酯的合成 |
| AU2015217221A1 (en) | 2014-02-13 | 2016-08-11 | Ligand Pharmaceuticals, Inc. | Prodrug compounds and their uses |
| CA2948148C (fr) | 2014-05-09 | 2022-12-06 | AuroMedics Pharma LLC | Formulations d'un concentre liquide de cyclophosphamide |
| JP2017520545A (ja) | 2014-07-02 | 2017-07-27 | リガンド・ファーマシューティカルズ・インコーポレイテッド | プロドラッグ化合物およびそれらの使用 |
| US10849916B2 (en) | 2014-07-11 | 2020-12-01 | Dr. Reddys Laboratories Limited | Stable liquid formulations of cyclophosphamide and its impurities |
| WO2016005962A2 (fr) | 2014-07-11 | 2016-01-14 | Dr. Reddy’S Laboratories Limited | Formulations liquides stables de cyclophosphamide et procédés associés |
| EP3197438A4 (fr) | 2014-09-26 | 2018-06-20 | Intas Pharmaceuticals Ltd. | Composition pharmaceutique présentant une uniformité de teneur améliorée |
| EP3915542B1 (fr) | 2014-12-23 | 2023-11-22 | Dyve Biosciences, Inc. | Formulations pour l'administration transdermique |
| WO2016156927A1 (fr) | 2015-04-02 | 2016-10-06 | PRZEDSIĘBIORSTWO PRODUKCYJNO-WDROŻENIOWE IFOTAM Sp. z o.o. | Procédé de production de n,n-bis (2-chloroéthyl)tétrahydro-2 h-1,3,2-oxazaphosphorine-2-amine 2-oxyde |
| WO2017207719A1 (fr) | 2016-06-02 | 2017-12-07 | Amneal Pharmaceuticals Company Gmbh | Composition de cyclophosphamide et son procédé de préparation |
| WO2019055880A2 (fr) | 2017-09-15 | 2019-03-21 | Ampersand Biopharmaceuticals, Inc. | Méthode d'administration et de traitement |
| CA3087932A1 (fr) | 2018-01-09 | 2019-07-18 | Ligand Pharmaceuticals, Inc. | Composes acetal et leurs utilisations therapeutiques |
| CN116178440B (zh) * | 2022-12-23 | 2025-12-30 | 杏林中医药科技(广州)有限公司 | 一种肝脏靶向烷化剂及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1065418B (de) * | 1953-03-21 | 1959-09-17 | Montecatini Soc. Gen. per 1'Industria Mineraria e Chimica, Mailand (Italien) | Verfahren zur Herstellung von heterocyclischen Phosphorverbindungen |
| NL236264A (fr) * | 1958-02-20 | 1900-01-01 |
-
0
- NL NL99688D patent/NL99688C/xx active
- BE BE563332D patent/BE563332A/xx unknown
- FR FR75178D patent/FR75178E/fr not_active Expired
- NL NL222157D patent/NL222157A/xx unknown
- BE BE554888D patent/BE554888A/xx unknown
- NL NL99649D patent/NL99649C/xx active
-
1956
- 1956-12-20 DE DEA26234A patent/DE1054997B/de active Pending
-
1957
- 1957-01-30 GB GB3283/57A patent/GB812651A/en not_active Expired
- 1957-02-04 FR FR731011A patent/FR1246708A/fr not_active Expired
- 1957-02-09 CH CH361279D patent/CH361279A/de unknown
- 1957-11-28 CH CH5317357A patent/CH369451A/de unknown
- 1957-12-04 DE DEA24298A patent/DE1057119B/de active Pending
- 1957-12-04 DE DEA28444A patent/DE1116672B/de active Pending
-
1958
- 1958-04-15 US US728568A patent/US3018302A/en not_active Expired - Lifetime
- 1958-12-03 GB GB39031/58A patent/GB853044A/en not_active Expired
- 1958-12-03 CH CH6689458A patent/CH370406A/de unknown
-
1959
- 1959-07-27 US US829528A patent/US3074992A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB812651A (en) | 1959-04-29 |
| FR1246708A (fr) | 1960-11-25 |
| NL99649C (fr) | |
| BE554888A (fr) | |
| GB853044A (en) | 1960-11-02 |
| NL99688C (fr) | |
| US3074992A (en) | 1963-01-22 |
| NL222157A (fr) | |
| CH369451A (de) | 1963-05-31 |
| DE1054997B (de) | 1959-04-16 |
| US3018302A (en) | 1962-01-23 |
| CH370406A (de) | 1963-07-15 |
| DE1057119B (de) | 1959-05-14 |
| BE563332A (fr) | |
| CH361279A (de) | 1962-04-15 |
| DE1116672B (de) | 1961-11-09 |