GR1000997B - Μεθοδος για την παρασκευη παραγωγων 8-χλωροκινολονης. - Google Patents
Μεθοδος για την παρασκευη παραγωγων 8-χλωροκινολονης.Info
- Publication number
- GR1000997B GR1000997B GR910100427A GR910100427A GR1000997B GR 1000997 B GR1000997 B GR 1000997B GR 910100427 A GR910100427 A GR 910100427A GR 910100427 A GR910100427 A GR 910100427A GR 1000997 B GR1000997 B GR 1000997B
- Authority
- GR
- Greece
- Prior art keywords
- group
- derivative
- formula
- finger member
- chloroquinolone
- Prior art date
Links
- JNXUGJMCFLONJN-UHFFFAOYSA-N 8-chloroquinolin-2(1H)-one Chemical class C1=CC(=O)NC2=C1C=CC=C2Cl JNXUGJMCFLONJN-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004466 alkoxycarbonylamino group Chemical group 0.000 abstract 1
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000005660 chlorination reaction Methods 0.000 abstract 1
- 125000004997 halocarbonyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- HVZWVEKIQMJYIK-UHFFFAOYSA-N nitryl chloride Chemical compound [O-][N+](Cl)=O HVZWVEKIQMJYIK-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- -1 quinolone compound Chemical class 0.000 abstract 1
- 125000003003 spiro group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27977890 | 1990-10-18 | ||
| JP22815391 | 1991-05-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GR910100427A GR910100427A (en) | 1992-09-25 |
| GR1000997B true GR1000997B (el) | 1993-03-31 |
Family
ID=26528079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR910100427A GR1000997B (el) | 1990-10-18 | 1991-10-17 | Μεθοδος για την παρασκευη παραγωγων 8-χλωροκινολονης. |
Country Status (16)
| Country | Link |
|---|---|
| KR (1) | KR100253047B1 (de) |
| CN (1) | CN1038509C (de) |
| AR (1) | AR247884A1 (de) |
| AT (1) | AT402501B (de) |
| EE (1) | EE03027B1 (de) |
| ES (1) | ES2039300B1 (de) |
| FI (1) | FI100531B (de) |
| GR (1) | GR1000997B (de) |
| HU (1) | HU221195B1 (de) |
| MX (1) | MX9101668A (de) |
| MY (1) | MY109714A (de) |
| NO (1) | NO179517C (de) |
| PL (1) | PL168831B1 (de) |
| PT (1) | PT99268B (de) |
| RU (1) | RU2049778C1 (de) |
| YU (1) | YU48819B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69231422T2 (de) * | 1991-05-28 | 2001-03-29 | Daiichi Pharmaceutical Co., Ltd. | Pyridoncarbonsäurederivate |
| ZA946853B (en) * | 1993-09-10 | 1995-04-24 | Daiichi Seiyaku Co | Crystals of antimicrobial compound. |
| CN1184221C (zh) * | 2001-08-08 | 2005-01-12 | 中国医学科学院医药生物技术研究所 | 有7-(7-氨甲基-5-氮杂螺[2,4]庚烷)取代基的新喹啉羧酸衍生物及其制备方法 |
| CN103483315B (zh) * | 2013-09-18 | 2015-07-01 | 浙江司太立制药股份有限公司 | 7-(3-氨甲基-4-烷氧亚胺基-1-吡咯烷基)-1-[(1r,2s)-2-氟环丙基]喹诺酮羧酸类化合物及其制备方法 |
| CN103709100A (zh) * | 2013-12-31 | 2014-04-09 | 南京工业大学 | 一种8-氯代喹诺酮衍生物的制备方法 |
| CN104892600B (zh) * | 2015-06-04 | 2017-02-01 | 浙江司太立制药股份有限公司 | 7‑(3‑氨甲基‑4‑取代苄氧亚胺基‑1‑吡咯烷基)萘啶酮羧酸类化合物 |
| CN105061395A (zh) * | 2015-08-10 | 2015-11-18 | 江苏吴中医药集团有限公司 | 一种西他沙星水合物的制备方法 |
| CN105669646B (zh) * | 2016-02-26 | 2018-03-09 | 济川药业集团有限公司 | 一种西他沙星的合成方法 |
| CN113527200B (zh) * | 2021-05-27 | 2022-12-02 | 北京斯利安药业有限公司 | 一种氯喹那多的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2840437A1 (de) * | 1978-09-16 | 1980-04-03 | Hoechst Ag | 8-chlor-5,6,7,8-tetrahydro-2-chinolon und 8-brom-5,6,7,8-tetrahydro-2-chinolon, deren hydrochlorid bzw. hydrobromid und verfahren zu deren herstellung |
| JPS6212760A (ja) * | 1984-12-14 | 1987-01-21 | Dai Ichi Seiyaku Co Ltd | 1−(2−ハロゲノシクロプロピル)キノリンカルボン酸誘導体 |
| JPH0635457B2 (ja) * | 1985-06-28 | 1994-05-11 | 杏林製薬株式会社 | ピリドンカルボン酸誘導体およびその製造方法 |
| DE3635218A1 (de) * | 1986-10-16 | 1988-04-21 | Bayer Ag | 7-amino-1-cyclopropyl-8-chlor-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| JPS6490183A (en) * | 1987-09-30 | 1989-04-06 | Kyorin Seiyaku Kk | Production of quinolonecarboxylic acid derivative |
| JPH0196786A (ja) * | 1987-10-09 | 1989-04-14 | Toshiba Corp | 改札装置のデータ集計処理方式 |
| IL90062A (en) * | 1988-04-27 | 1994-10-07 | Daiichi Seiyaku Co | Pyridonecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them |
| CA1336090C (en) * | 1988-08-31 | 1995-06-27 | Isao Hayakawa | Spiro-substituted cyclic amines of quinolone derivatives |
-
1991
- 1991-10-12 MY MYPI91001865A patent/MY109714A/en unknown
- 1991-10-14 YU YU165791A patent/YU48819B/sh unknown
- 1991-10-16 NO NO914053A patent/NO179517C/no unknown
- 1991-10-16 FI FI914875A patent/FI100531B/fi active
- 1991-10-17 AR AR91320942A patent/AR247884A1/es active
- 1991-10-17 GR GR910100427A patent/GR1000997B/el not_active IP Right Cessation
- 1991-10-17 ES ES09102304A patent/ES2039300B1/es not_active Expired - Fee Related
- 1991-10-17 RU SU915010041A patent/RU2049778C1/ru not_active IP Right Cessation
- 1991-10-17 PT PT99268A patent/PT99268B/pt not_active IP Right Cessation
- 1991-10-17 AT AT0206691A patent/AT402501B/de not_active IP Right Cessation
- 1991-10-17 PL PL91292087A patent/PL168831B1/pl not_active IP Right Cessation
- 1991-10-17 HU HU280/91A patent/HU221195B1/hu not_active IP Right Cessation
- 1991-10-18 CN CN91110833A patent/CN1038509C/zh not_active Expired - Lifetime
- 1991-10-18 MX MX9101668A patent/MX9101668A/es unknown
- 1991-10-18 KR KR1019910018376A patent/KR100253047B1/ko not_active Expired - Lifetime
-
1994
- 1994-11-22 EE EE9400253A patent/EE03027B1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATA206691A (de) | 1996-10-15 |
| ES2039300B1 (es) | 1994-05-16 |
| FI914875A0 (fi) | 1991-10-16 |
| AT402501B (de) | 1997-06-25 |
| NO914053D0 (no) | 1991-10-16 |
| ES2039300A1 (es) | 1993-09-16 |
| PT99268B (pt) | 1999-04-30 |
| GR910100427A (en) | 1992-09-25 |
| AR247884A1 (es) | 1995-04-28 |
| YU48819B (sh) | 2001-12-26 |
| KR100253047B1 (ko) | 2000-05-01 |
| PL168831B1 (pl) | 1996-04-30 |
| NO179517C (no) | 1996-10-23 |
| CN1062906A (zh) | 1992-07-22 |
| PL292087A1 (en) | 1992-11-16 |
| YU165791A (sh) | 1994-05-10 |
| HU221195B1 (en) | 2002-08-28 |
| FI100531B (fi) | 1997-12-31 |
| HUT59388A (en) | 1992-05-28 |
| MX9101668A (es) | 1992-06-05 |
| NO179517B (no) | 1996-07-15 |
| KR920008007A (ko) | 1992-05-27 |
| EE03027B1 (et) | 1997-08-15 |
| PT99268A (pt) | 1992-08-31 |
| FI914875A7 (fi) | 1992-04-19 |
| RU2049778C1 (ru) | 1995-12-10 |
| CN1038509C (zh) | 1998-05-27 |
| NO914053L (no) | 1992-04-21 |
| HU913280D0 (en) | 1992-01-28 |
| MY109714A (en) | 1997-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ML | Lapse due to non-payment of fees |