GR3036622T3 - Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds - Google Patents

Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Info

Publication number: GR3036622T3
Authority: GR; Greece
Prior art keywords: quaternary ammonium; compositions containing; ammonium compounds; polymeric quaternary; containing polymeric
Prior art date: 1994-11-16

Application number

GR20010401480T

Other languages

Greek (el)

English (en)

Inventor

Suketu Dipakbhai Desai

Diane S Nelms

Original Assignee

Alcon Lab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-16

Filing date

2001-09-17

Publication date

2001-12-31

2001-09-17 Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc

2001-12-31 Publication of GR3036622T3 publication Critical patent/GR3036622T3/el

Links

239000000203 mixture Substances 0.000 title abstract 2
150000003856 quaternary ammonium compounds Chemical class 0.000 title abstract 2
239000003732 agents acting on the eye Substances 0.000 title 1
229940023490 ophthalmic product Drugs 0.000 title 1
230000002378 acidificating effect Effects 0.000 abstract 1
KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
239000004327 boric acid Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Ophthalmology & Optometry (AREA)
Inorganic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

GR20010401480T 1994-11-16 2001-09-17 Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds GR3036622T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/340,763 US5603929A (en)	1994-11-16	1994-11-16	Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
PCT/US1995/014910 WO1996014829A1 (en)	1994-11-16	1995-11-16	Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Publications (1)

Publication Number	Publication Date
GR3036622T3 true GR3036622T3 (en)	2001-12-31

Family

ID=23334841

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR20010401480T GR3036622T3 (en)	1994-11-16	2001-09-17	Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Country Status (12)

Country	Link
US (2)	US5603929A (de)
EP (1)	EP0739197B1 (de)
JP (1)	JP2954356B2 (de)
AT (1)	ATE203897T1 (de)
AU (1)	AU686917B2 (de)
CA (1)	CA2180554C (de)
DE (1)	DE69522094T2 (de)
DK (1)	DK0739197T3 (de)
ES (1)	ES2160722T3 (de)
GR (1)	GR3036622T3 (de)
PT (1)	PT739197E (de)
WO (1)	WO1996014829A1 (de)

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JP4286480B2 (ja) *	2001-09-17	2009-07-01	株式会社メニコン	殺菌液
WO2004064828A1 (ja)	2003-01-21	2004-08-05	Senju Pharmaceutical Co., Ltd.	２−アミノ−３−(４−ブロモベンゾイル)フェニル酢酸含有水性液剤
CA2505836C (en) *	2004-05-06	2013-08-27	Alcon Inc.	Topical brimonidine tartrate formulations that lack chlorine dioxide
US20060073184A1 (en) *	2004-09-29	2006-04-06	Bausch & Lomb Inc.	Viscoelastic composition, methods of use and packaging device with anti-oxidant
WO2006049250A1 (ja)	2004-11-05	2006-05-11	Senju Pharmaceutical Co., Ltd.	眼内移行性促進水性点眼剤
JP5108234B2 (ja) *	2005-02-07	2012-12-26	日本特殊陶業株式会社	マイクロヒータ及びセンサ
US7947010B2 (en)	2005-07-08	2011-05-24	Depuy Products, Inc.	Composition and system for wound decontamination
US20100130580A1 (en) *	2006-01-25	2010-05-27	Aciex Therapeutics, Inc.	Formulations and Methods for Treating Dry Eye
CA2621616A1 (en) *	2007-02-19	2008-08-19	Alcon Research, Ltd.	Topical gatifloxacin formulations
US7705112B2 (en) *	2007-04-17	2010-04-27	Abbott Medical Optics Inc.	Polyquaternium-1 synthesis methods
CN101754748A (zh) *	2007-05-24	2010-06-23	阿西克斯医疗公司	治疗干眼症的制剂和方法
JP5668476B2 (ja)	2007-10-08	2015-02-12	オーリニア・ファーマシューティカルズ・インコーポレイテッドＡｕｒｉｎｉａＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃ．	カルシニューリン阻害剤またはｍＴＯＲ阻害剤を含む眼科用組成物
CA2716110A1 (en) *	2008-02-21	2009-08-27	Tim Mcnamara	Ophthalmic nsaids as adjuvants
RU2431469C1 (ru) *	2008-03-03	2011-10-20	Аллерган, Инк.	Композиции кеторолака трометамина для лечения или профилактики глазной боли
US9192571B2 (en)	2008-03-03	2015-11-24	Allergan, Inc.	Ketorolac tromethamine compositions for treating or preventing ocular pain
AU2009225931B9 (en)	2008-03-17	2014-04-03	Novartis Ag	Aqueous pharmaceutical compositions containing borate-polyol complexes
TWI544927B (zh)	2008-03-17	2016-08-11	愛爾康研究有限公司	具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
TWI454289B (zh) *	2008-04-03	2014-10-01	Alcon Res Ltd	使用順式二醇的聚合物於抑制陽離子殺生物劑被吸收進入水凝膠生物材質中之用途
TW201038295A (en)	2009-04-17	2010-11-01	Alcon Res Ltd	Aqueous ophthalmic compositions containing anionic therapeutic agents
EP2440185B1 (de)	2009-06-09	2015-04-08	Aurinia Pharmaceuticals Inc.	Topische arzneimittelabgabesysteme zur ophthalmischen verwendung
TWI489997B (zh)	2009-06-19	2015-07-01	Alcon Res Ltd	含有硼酸－多元醇錯合物之水性藥學組成物
US9107888B2 (en)	2011-01-18	2015-08-18	Senju Pharmaceutical Co., Ltd.	Aqueous liquid bromfenac composition having preservative efficacy
EP2919755B1 (de)	2012-11-19	2018-02-21	Bausch & Lomb Incorporated	Wässrige flüssigzusammensetzung mit 2-amino-3-(4-brombenzoyl-)phenylessigsäure
WO2014204952A1 (en)	2013-06-19	2014-12-24	Sentiss Research Center	Stable bromfenac solution
BR112016003692B1 (pt)	2013-08-20	2022-02-08	3M Innovative Properties Company	Complexo poliéter boro-silano
US20170000889A1 (en)	2013-12-12	2017-01-05	Sentiss Pharma Private Limited	Stable bromfenac ophthalmic solution
US10632202B2 (en)	2016-03-04	2020-04-28	Johnson & Johnson Consumer Inc.	Preservative containing compositions
US20190224275A1 (en)	2017-05-12	2019-07-25	Aurinia Pharmaceuticals Inc.	Protocol for treatment of lupus nephritis
US20230159202A1 (en) *	2021-11-23	2023-05-25	Bausch + Lomb Ireland Limited	Method for making a preservative-free packaged ophthalmic device product

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US3931319A (en) *	1974-10-29	1976-01-06	Millmaster Onyx Corporation	Capped polymers
US4027020A (en) *	1974-10-29	1977-05-31	Millmaster Onyx Corporation	Randomly terminated capped polymers
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US4822819A (en) *	1986-11-07	1989-04-18	Alcon Laboratories, Inc.	Use of trimoprostil and derivatives in glaucoma therapy
US4822820A (en) *	1986-11-24	1989-04-18	Alcon Laboratories, Inc.	Use of tri-methyl PG-F2 a and derivatives in glaucoma therapy
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IE63392B1 (en) *	1988-02-08	1995-04-19	Insite Vision Inc	Ophthalmic suspensions
US5188826A (en) *	1988-02-08	1993-02-23	Insite Vision Incorporated	Topical ophthalmic suspensions
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US5149693A (en) *	1988-03-09	1992-09-22	Alcon Laboratories, Inc.	Combination of tobramycin and fluorometholone for topical ophthalmic use
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US4960799A (en) *	1988-09-13	1990-10-02	Ciba-Geigy Corporation	Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
US5037647A (en) *	1988-09-15	1991-08-06	Alcon Laboratories, Inc.	Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride
US5145643A (en) *	1990-01-05	1992-09-08	Allergan, Inc.	Nonoxidative ophthalmic compositions and methods for preserving and using same
DE69333850T3 (de) *	1992-05-06	2011-03-17	Alcon Laboratories, Inc., Fort Worth	Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen
US5300287A (en) *	1992-11-04	1994-04-05	Alcon Laboratories, Inc.	Polymeric antimicrobials and their use in pharmaceutical compositions
AU6021794A (en) *	1993-01-11	1994-08-15	Allergan, Inc.	Ophthalmic compositions comprising benzyllauryldimethylammonium chloride

1994
- 1994-11-16 US US08/340,763 patent/US5603929A/en not_active Expired - Lifetime
1995
- 1995-11-16 WO PCT/US1995/014910 patent/WO1996014829A1/en not_active Ceased
- 1995-11-16 CA CA002180554A patent/CA2180554C/en not_active Expired - Lifetime
- 1995-11-16 EP EP95939996A patent/EP0739197B1/de not_active Expired - Lifetime
- 1995-11-16 AU AU41622/96A patent/AU686917B2/en not_active Expired
- 1995-11-16 AT AT95939996T patent/ATE203897T1/de active
- 1995-11-16 DE DE69522094T patent/DE69522094T2/de not_active Expired - Lifetime
- 1995-11-16 DK DK95939996T patent/DK0739197T3/da active
- 1995-11-16 ES ES95939996T patent/ES2160722T3/es not_active Expired - Lifetime
- 1995-11-16 JP JP8509750A patent/JP2954356B2/ja not_active Expired - Lifetime
- 1995-11-16 PT PT95939996T patent/PT739197E/pt unknown
1996
- 1996-08-21 US US08/700,960 patent/US5653972A/en not_active Expired - Lifetime
2001
- 2001-09-17 GR GR20010401480T patent/GR3036622T3/el unknown

Also Published As

Publication number	Publication date
ES2160722T3 (es)	2001-11-16
ATE203897T1 (de)	2001-08-15
WO1996014829A1 (en)	1996-05-23
DE69522094D1 (de)	2001-09-13
EP0739197A1 (de)	1996-10-30
JPH09503791A (ja)	1997-04-15
US5603929A (en)	1997-02-18
AU686917B2 (en)	1998-02-12
CA2180554A1 (en)	1996-05-23
EP0739197B1 (de)	2001-08-08
AU4162296A (en)	1996-06-06
HK1012556A1 (en)	1999-08-06
DE69522094T2 (de)	2001-11-22
CA2180554C (en)	2001-08-21
JP2954356B2 (ja)	1999-09-27
US5653972A (en)	1997-08-05
PT739197E (pt)	2001-12-28
DK0739197T3 (da)	2001-10-29

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ATE203897T1 (de)	2001-08-15	Konservierungsmittelhaltige ophtalmisch anzuwendende arzneizusammensetzungen enthaltend quaternäre polymerammoniumverbindungen
GR3018893T3 (en)	1996-05-31	Gel composition in a dispenser.
PL319833A1 (en)	1997-09-01	Compounds and composition for carrying active media
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EG20670A (en)	1999-11-30	Active substance delivery system
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IL112627A0 (en)	1995-05-26	Diketopiperazines, their preparation and pharmaceutical or veterinary compositions containing them
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CA2294448A1 (en)	1998-12-30	Pharmaceutical combination preparations containing erythropoietin and modified haemoglobins
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ZA973016B (en)	1997-11-04	Transdermally administered acetylcysteine as mucolytic agent.
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EP0190860A3 (de)	1987-06-03	6-Chloro-3-methyl-1H-2,3,4,5-tetrahydro-3-benzazepin-N-oxyd und dieses enthaltende Arzneimittel
EP0595226A3 (en)	1994-08-17	Active substance-containing polymer gel
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UA28284A (uk)	2000-10-16	Природний лікувальний засіб (його варіанти)
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