GR81143B - Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents - Google Patents

Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents

Info

Publication number: GR81143B
Authority: GR; Greece
Prior art keywords: pyridylmethyl; thio; substituted; antisecretory agents; gastric antisecretory
Prior art date: 1983-12-05

Application number

GR81143A

Other languages

English (en)

Inventor

Sih Charles John

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-05

Filing date

1984-12-03

Publication date

1985-04-04

1984-12-03 Application filed by Upjohn Co filed Critical Upjohn Co

1985-04-04 Publication of GR81143B publication Critical patent/GR81143B/el

Links

-1 2-pyridylmethyl-thio Chemical group 0.000 title 1
MMJMSRMOAUITKN-UHFFFAOYSA-N 2-sulfinylbenzimidazole Chemical class C1=CC=CC2=NC(=S=O)N=C21 MMJMSRMOAUITKN-UHFFFAOYSA-N 0.000 title 1
230000002496 gastric effect Effects 0.000 title 1
239000002731 stomach secretion inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

GR81143A 1983-12-05 1984-12-03 Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents GR81143B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US55808783A	1983-12-05	1983-12-05
US06/648,118 US4575554A (en)	1983-12-05	1984-09-06	Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents

Publications (1)

Publication Number	Publication Date
GR81143B true GR81143B (en)	1985-04-04

Family

ID=27071629

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR81143A GR81143B (en)	1983-12-05	1984-12-03	Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents

Country Status (16)

Country	Link
US (1)	US4575554A (el)
EP (1)	EP0150586B1 (el)
JP (1)	JPS60139689A (el)
KR (1)	KR890000382B1 (el)
AU (1)	AU571907B2 (el)
DE (1)	DE3484565D1 (el)
DK (1)	DK577584A (el)
ES (1)	ES8603711A1 (el)
FI (1)	FI83418C (el)
GR (1)	GR81143B (el)
IE (1)	IE58431B1 (el)
IL (1)	IL73433A (el)
MX (1)	MX160796A (el)
NO (1)	NO164473C (el)
NZ (1)	NZ210135A (el)
PH (1)	PH19962A (el)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2161160B (en) *	1984-07-06	1989-05-24	Fisons Plc	Heterocyclic sulphinyl compounds
JPS6150979A (ja) *	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
JPS6150978A (ja) *	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
EP0178438A1 (en) *	1984-09-19	1986-04-23	Beecham Group Plc	Novel compounds
KR890000387B1 (ko) *	1984-09-24	1989-03-16	디 엎존 캄파니	2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법
JO1406B1 (en) *	1984-11-02	1986-11-30	سميث كلاين اند فرينش لابوراتوريز ليمتد	Chemical compounds
US4743609A (en) *	1985-02-12	1988-05-10	Banyu Pharmaceutical Co., Ltd.	Indole derivatives having gastric and antisecretory and cytoprotective properties, and pharmaceutical preparations containing same
EP0234485B1 (de) *	1986-02-20	1992-04-01	Hoechst Aktiengesellschaft	Substituierte Thienoimidazol-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zubereitungen und ihre Verwendung als Magensäuresekretionshemmer
WO1987005296A1 (en) *	1986-03-07	1987-09-11	Pfizer Inc.	2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
US4772619A (en) *	1986-07-17	1988-09-20	G. D. Searle & Co.	[(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
JPH03505450A (ja) *	1988-06-30	1991-11-28	ジ・アップジョン・カンパニー	胃腸病用の経皮抗分泌剤
US4965269A (en) *	1989-12-20	1990-10-23	Ab Hassle	Therapeutically active chloro substituted benzimidazoles
WO1994013290A1 (de) *	1992-12-10	1994-06-23	Byk Gulden Lomberg Chemische Fabrik Gmbh	Verwendung von alkylthiopyridinen zur bekämpfung von heliobacter-bakterien
UA32583C2 (uk) *	1993-06-29	2001-02-15	Бік Гульден Ломберг Хеміше Фабрік Гмбх	Похідні арилтіоалкілтіопіридину
FI964908L (fi) *	1994-06-10	1996-12-09	Byk Gulden Lomberg Chem Fab	Helicobacter-bakteerien torjuntaan tarkoitetut tiopyridiinit
US6207198B1 (en) *	1995-09-21	2001-03-27	Schwarz Pharma Ag	Composition containing an acid-labile omeprazole and process for its preparation
US6245913B1 (en)	1999-06-30	2001-06-12	Wockhardt Europe Limited	Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
WO2002026210A2 (en) *	2000-09-29	2002-04-04	Geneva Pharmaceuticals Inc.	Proton pump inhibitor formulation
US20030228363A1 (en) *	2002-06-07	2003-12-11	Patel Mahendra R.	Stabilized pharmaceutical compositons containing benzimidazole compounds
US20060024362A1 (en)	2004-07-29	2006-02-02	Pawan Seth	Composition comprising a benzimidazole and process for its manufacture
EP3512840B1 (en) *	2016-09-14	2024-03-06	Yufeng Jane Tseng	Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors
CN112142653B (zh) *	2020-10-22	2022-02-11	成都百泉生物医药科技有限公司	奥美拉唑中间体的制备方法
WO2025085783A1 (en) *	2023-10-20	2025-04-24	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Prazole-based antiviral therapeutics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE418966B (sv) *	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) *	1974-05-16	1981-01-26	Haessle Ab	Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) *	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
US4359465A (en) *	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
IL66340A (en) *	1981-08-13	1986-08-31	Haessle Ab	Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
JPS58135881A (ja) *	1981-11-05	1983-08-12	ビク−グルデン・ロムベルク・ヘミツシエ・フアブリク・ゲゼルシヤフト・ミト・ベシユレンクテル・ハフツング	置換ベンズイミダゾ−ル類、その製造方法と利用、およびこれを含む医薬
US4472409A (en) *	1981-11-05	1984-09-18	Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung	2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
DE3216843C2 (de) *	1982-05-05	1986-10-23	Ludwig Heumann & Co GmbH, 8500 Nürnberg	3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) *	1983-02-11	1983-02-11	Haessle Ab	Novel pharmacologically active compounds

1984
- 1984-09-06 US US06/648,118 patent/US4575554A/en not_active Expired - Fee Related
- 1984-11-05 IL IL73433A patent/IL73433A/xx unknown
- 1984-11-07 NZ NZ210135A patent/NZ210135A/xx unknown
- 1984-11-14 MX MX203387A patent/MX160796A/es unknown
- 1984-11-19 AU AU35643/84A patent/AU571907B2/en not_active Ceased
- 1984-12-03 PH PH31520A patent/PH19962A/en unknown
- 1984-12-03 EP EP84308376A patent/EP0150586B1/en not_active Expired - Lifetime
- 1984-12-03 GR GR81143A patent/GR81143B/el unknown
- 1984-12-03 FI FI844755A patent/FI83418C/fi not_active IP Right Cessation
- 1984-12-03 DE DE8484308376T patent/DE3484565D1/de not_active Expired - Fee Related
- 1984-12-04 ES ES538249A patent/ES8603711A1/es not_active Expired
- 1984-12-04 JP JP59257268A patent/JPS60139689A/ja active Granted
- 1984-12-04 DK DK577584A patent/DK577584A/da not_active Application Discontinuation
- 1984-12-04 KR KR1019840007636A patent/KR890000382B1/ko not_active Expired
- 1984-12-04 NO NO844836A patent/NO164473C/no unknown
- 1984-12-04 IE IE309584A patent/IE58431B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH0572392B2 (el)	1993-10-12
ES538249A0 (es)	1986-01-16
JPS60139689A (ja)	1985-07-24
NO164473C (no)	1990-10-10
DK577584A (da)	1985-06-06
AU3564384A (en)	1985-06-13
FI844755A0 (fi)	1984-12-03
FI83418C (fi)	1991-07-10
IL73433A0 (en)	1985-02-28
IE58431B1 (en)	1993-09-22
KR890000382B1 (ko)	1989-03-15
AU571907B2 (en)	1988-04-28
DK577584D0 (da)	1984-12-04
ES8603711A1 (es)	1986-01-16
FI844755L (fi)	1985-06-06
US4575554A (en)	1986-03-11
PH19962A (en)	1986-08-20
NZ210135A (en)	1989-01-06
KR850004483A (ko)	1985-07-15
MX160796A (es)	1990-05-22
EP0150586B1 (en)	1991-05-08
FI83418B (fi)	1991-03-28
NO844836L (no)	1985-06-06
NO164473B (no)	1990-07-02
IL73433A (en)	1988-11-30
IE843095L (en)	1985-06-05
EP0150586A2 (en)	1985-08-07
DE3484565D1 (de)	1991-06-13
EP0150586A3 (en)	1985-08-28

Publication	Publication Date	Title
GR81143B (en)	1985-04-04	Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents
GB8307865D0 (en)	1983-04-27	Benzimidazole derivatives
ZA836958B (en)	1985-04-24	Benzimidazoles
GB8316704D0 (en)	1983-07-20	Interlinings
GB2147028B (en)	1986-11-12	Buildings' devices
GB8329138D0 (en)	1983-12-07	Drilling
EP0133071A3 (en)	1986-03-26	Modified organophilic clay
DE3466462D1 (en)	1987-11-05	Extendible boom
GB8405981D0 (en)	1984-04-11	Release additives
DE3468479D1 (en)	1988-02-11	Drilling arm
GB8333550D0 (en)	1984-01-25	Coupling devices
GB2195685B (en)	1990-04-25	Additives for controlling or modifying thixotropic properties
GB2134072B (en)	1985-10-09	Booms
GB2137439B (en)	1986-12-03	Conductor rail joint
ZA845044B (en)	1985-03-27	Anti-ulcer agents
PH24626A (en)	1990-08-17	Heterocyclic substituted benzimidazoles
DE3474050D1 (en)	1988-10-20	Drilling device
ZA849635B (en)	1985-07-31	Coupling devices
ZA848746B (en)	1985-07-31	Substituted 2-pyridylmethyl-thio and-sulfinyl benzimidazoles as gastric antisecretory agents
GB8316396D0 (en)	1983-07-20	Drilling devices
GB8310146D0 (en)	1983-05-18	Benzimidazole derivatives
GB8319213D0 (en)	1983-08-17	Boom structure
ZA843410B (en)	1984-12-24	Drilling equipment
GB8401712D0 (en)	1984-02-22	Hold open devices
IE820026L (en)	1982-07-09	Pyridine substituted benzimidazoles