GR940300047T1 - Methods of detecting bone resorption in vivo - Google Patents

Methods of detecting bone resorption in vivo

Info

Publication number
GR940300047T1
GR940300047T1 GR940300047T GR940300047T GR940300047T1 GR 940300047 T1 GR940300047 T1 GR 940300047T1 GR 940300047 T GR940300047 T GR 940300047T GR 940300047 T GR940300047 T GR 940300047T GR 940300047 T1 GR940300047 T1 GR 940300047T1
Authority
GR
Greece
Prior art keywords
bone resorption
vivo
methods
detecting bone
pyridinoline
Prior art date
Application number
GR940300047T
Other languages
English (en)
Inventor
David R Eyre
Original Assignee
Washington Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27034100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR940300047(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/444,881 external-priority patent/US5140103A/en
Application filed by Washington Res Found filed Critical Washington Res Found
Publication of GR940300047T1 publication Critical patent/GR940300047T1/el

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02Linear peptides containing at least one abnormal peptide link
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4712Muscle proteins, e.g. myosin, actin, protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/105Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/108Osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GR940300047T 1989-12-01 1994-07-29 Methods of detecting bone resorption in vivo GR940300047T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/444,881 US5140103A (en) 1987-11-06 1989-12-01 Peptide fragments containing HP and LP cross-links
US07/614,719 US5300434A (en) 1987-11-06 1990-11-21 Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
PCT/US1990/007015 WO1991008478A2 (en) 1989-12-01 1990-11-30 METHODS OF DETECTING COLLAGEN DEGRADATION $i(IN VIVO)

Publications (1)

Publication Number Publication Date
GR940300047T1 true GR940300047T1 (en) 1994-07-29

Family

ID=27034100

Family Applications (3)

Application Number Title Priority Date Filing Date
GR940300047T GR940300047T1 (en) 1989-12-01 1994-07-29 Methods of detecting bone resorption in vivo
GR960400036T GR3018852T3 (en) 1989-12-01 1996-02-01 Methods of detecting bone resorption in vivo
GR990401732T GR3030646T3 (en) 1989-12-01 1999-06-30 Methods of detecting collagen degradation in vivo.

Family Applications After (2)

Application Number Title Priority Date Filing Date
GR960400036T GR3018852T3 (en) 1989-12-01 1996-02-01 Methods of detecting bone resorption in vivo
GR990401732T GR3030646T3 (en) 1989-12-01 1999-06-30 Methods of detecting collagen degradation in vivo.

Country Status (13)

Country Link
US (5) US5300434A (el)
EP (6) EP1560026A1 (el)
JP (6) JP2782017B2 (el)
AT (3) ATE179521T1 (el)
AU (1) AU645049B2 (el)
DE (4) DE502928T1 (el)
DK (3) DK0682256T3 (el)
ES (2) ES2133656T3 (el)
GR (3) GR940300047T1 (el)
IE (1) IE65280B1 (el)
NO (1) NO309483B1 (el)
RU (1) RU2139541C1 (el)
WO (1) WO1991008478A2 (el)

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US6153732A (en) * 1987-11-06 2000-11-28 Washington Research Foundation Kit for detecting analyte indicative of type II collagen resorption in vivo
US4973666A (en) * 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
US5320970A (en) * 1987-11-06 1994-06-14 Washington Research Foundation Detection of collagen degradation in vivo
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Also Published As

Publication number Publication date
RU2139541C1 (ru) 1999-10-10
JP2782017B2 (ja) 1998-07-30
DE69033082D1 (de) 1999-06-02
US5677198A (en) 1997-10-14
EP1632502A1 (en) 2006-03-08
IE904344A1 (en) 1991-06-05
ES2061422T1 (es) 1994-12-16
JPH05502223A (ja) 1993-04-22
JP2002139492A (ja) 2002-05-17
EP0682256A1 (en) 1995-11-15
JPH10260183A (ja) 1998-09-29
NO922149L (no) 1992-07-29
DE69034170D1 (de) 2004-11-18
JP2999416B2 (ja) 2000-01-17
DE69025199D1 (de) 1996-03-14
WO1991008478A2 (en) 1991-06-13
EP0502928A1 (en) 1992-09-16
EP0502928B1 (en) 1996-01-31
EP0682257A1 (en) 1995-11-15
EP1560026A1 (en) 2005-08-03
DK0502928T3 (da) 1996-02-19
NO922149D0 (no) 1992-05-29
DK0682256T3 (da) 2005-02-14
GR3018852T3 (en) 1996-05-31
ES2061422T3 (es) 1996-03-16
EP0890840A3 (en) 2000-05-17
JP2000050865A (ja) 2000-02-22
ATE133790T1 (de) 1996-02-15
GR3030646T3 (en) 1999-10-29
DE69033082T2 (de) 1999-09-30
JP3299941B2 (ja) 2002-07-08
AU645049B2 (en) 1994-01-06
AU6889891A (en) 1991-06-26
EP0890840A2 (en) 1999-01-13
ATE279730T1 (de) 2004-10-15
NO309483B1 (no) 2001-02-05
JPH09113510A (ja) 1997-05-02
EP0682256B1 (en) 2004-10-13
JP2999444B2 (ja) 2000-01-17
DK0682257T3 (da) 1999-11-08
DE502928T1 (de) 1994-08-18
US5576189A (en) 1996-11-19
US5473052A (en) 1995-12-05
ATE179521T1 (de) 1999-05-15
DE69034170T2 (de) 2006-03-02
US5300434A (en) 1994-04-05
EP0682257B1 (en) 1999-04-28
DE69025199T2 (de) 1996-05-30
ES2133656T3 (es) 1999-09-16
WO1991008478A3 (en) 1991-11-28
JP2000055915A (ja) 2000-02-25
US5656439A (en) 1997-08-12
IE65280B1 (en) 1995-10-18

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