HRP20000793A2 - Improved method for preparing pharmaceutically valuable norbenzomorphane derivatives - Google Patents

Improved method for preparing pharmaceutically valuable norbenzomorphane derivatives Download PDF

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Publication number
HRP20000793A2
HRP20000793A2 HR20000793A HRP20000793A HRP20000793A2 HR P20000793 A2 HRP20000793 A2 HR P20000793A2 HR 20000793 A HR20000793 A HR 20000793A HR P20000793 A HRP20000793 A HR P20000793A HR P20000793 A2 HRP20000793 A2 HR P20000793A2
Authority
HR
Croatia
Prior art keywords
acid
piperidine
aluminum
derivative
reaction
Prior art date
Application number
HR20000793A
Other languages
English (en)
Croatian (hr)
Inventor
Matthias Grauert
Hanfried Baltes
Juergen Schnaubelt
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of HRP20000793A2 publication Critical patent/HRP20000793A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
HR20000793A 1998-05-20 1999-05-07 Improved method for preparing pharmaceutically valuable norbenzomorphane derivatives HRP20000793A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19822822A DE19822822A1 (de) 1998-05-20 1998-05-20 Verbessertes Verfahren zur Herstellung von pharmazeutisch wertvollen Norbenzomorphanderivaten
PCT/EP1999/003142 WO1999059976A1 (fr) 1998-05-20 1999-05-07 Procede ameliore de production de derives de norbenzomorphane precieux sur le plan pharmaceutique

Publications (1)

Publication Number Publication Date
HRP20000793A2 true HRP20000793A2 (en) 2001-10-31

Family

ID=7868527

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000793A HRP20000793A2 (en) 1998-05-20 1999-05-07 Improved method for preparing pharmaceutically valuable norbenzomorphane derivatives

Country Status (37)

Country Link
US (1) US6124459A (fr)
EP (1) EP1080076B1 (fr)
JP (1) JP4526185B2 (fr)
KR (1) KR20010043703A (fr)
CN (1) CN1113058C (fr)
AR (1) AR016040A1 (fr)
AT (1) ATE254605T1 (fr)
AU (1) AU753563B2 (fr)
BG (1) BG104964A (fr)
BR (1) BR9910603A (fr)
CA (1) CA2330669C (fr)
CO (1) CO5060460A1 (fr)
DE (2) DE19822822A1 (fr)
DK (1) DK1080076T3 (fr)
EA (1) EA003059B1 (fr)
EE (1) EE04305B1 (fr)
EG (1) EG21526A (fr)
ES (1) ES2211093T3 (fr)
HR (1) HRP20000793A2 (fr)
HU (1) HUP0102034A3 (fr)
ID (1) ID27014A (fr)
IL (1) IL138998A0 (fr)
MY (1) MY120806A (fr)
NO (1) NO317302B1 (fr)
NZ (1) NZ508845A (fr)
PE (1) PE20000558A1 (fr)
PL (1) PL343935A1 (fr)
PT (1) PT1080076E (fr)
SI (1) SI1080076T1 (fr)
SK (1) SK283996B6 (fr)
TR (1) TR200003360T2 (fr)
TW (1) TW455582B (fr)
UA (1) UA59448C2 (fr)
UY (1) UY25515A1 (fr)
WO (1) WO1999059976A1 (fr)
YU (1) YU71400A (fr)
ZA (1) ZA200005740B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7405149B1 (en) * 1998-12-21 2008-07-29 Megica Corporation Post passivation method for semiconductor chip or wafer
WO2016044546A1 (fr) * 2014-09-17 2016-03-24 Purdue Pharma L.P. Analogues de benzomorphane et leur utilisation
CN107089948B (zh) * 2017-04-28 2020-07-17 云南大学 吗吩衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE34235B1 (en) * 1969-06-04 1975-03-19 Acf Chemiefarma Nv 6,7-benzomorphans and their preparation
US3932422A (en) * 1974-05-20 1976-01-13 Sterling Drug Inc. 8-Methylene-3-azabicyclo[3.3.1]non-6-en-4-ones
US4255579A (en) * 1974-05-20 1981-03-10 Sterling Drug Inc. 11-Substituted hexahydro-2,6-methano-3-benzazocines
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan

Also Published As

Publication number Publication date
SK283996B6 (sk) 2004-07-07
UY25515A1 (es) 1999-12-13
ZA200005740B (en) 2001-10-17
CN1301256A (zh) 2001-06-27
DK1080076T3 (da) 2004-03-22
EE200000674A (et) 2002-04-15
DE19822822A1 (de) 1999-11-25
YU71400A (sh) 2003-04-30
ATE254605T1 (de) 2003-12-15
NO20005818D0 (no) 2000-11-17
UA59448C2 (uk) 2003-09-15
ES2211093T3 (es) 2004-07-01
ID27014A (id) 2001-02-22
HK1035728A1 (en) 2001-12-07
AU4139999A (en) 1999-12-06
EP1080076B1 (fr) 2003-11-19
TW455582B (en) 2001-09-21
CO5060460A1 (es) 2001-07-30
CA2330669C (fr) 2008-07-15
CA2330669A1 (fr) 1999-11-25
AR016040A1 (es) 2001-05-30
NZ508845A (en) 2002-11-26
CN1113058C (zh) 2003-07-02
PE20000558A1 (es) 2000-06-28
HUP0102034A3 (en) 2002-02-28
MY120806A (en) 2005-11-30
BG104964A (bg) 2001-07-31
NO20005818L (no) 2000-11-17
JP4526185B2 (ja) 2010-08-18
US6124459A (en) 2000-09-26
PT1080076E (pt) 2004-04-30
DE59907804D1 (de) 2003-12-24
AU753563B2 (en) 2002-10-24
KR20010043703A (ko) 2001-05-25
SK17312000A3 (sk) 2001-06-11
BR9910603A (pt) 2001-01-16
EG21526A (en) 2001-11-28
EE04305B1 (et) 2004-06-15
JP2002515491A (ja) 2002-05-28
NO317302B1 (no) 2004-10-04
PL343935A1 (en) 2001-09-10
EP1080076A1 (fr) 2001-03-07
EA200001212A1 (ru) 2001-04-23
SI1080076T1 (sl) 2004-04-30
HUP0102034A2 (hu) 2001-12-28
EA003059B1 (ru) 2002-12-26
WO1999059976A1 (fr) 1999-11-25
IL138998A0 (en) 2001-11-25
TR200003360T2 (tr) 2001-06-21

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PNAN Change of the applicant name, address/residence

Owner name: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG., DE

OBST Application withdrawn