HRP20010496A2 - Modulation of immune response by ribavirin - Google Patents

Modulation of immune response by ribavirin Download PDF

Info

Publication number
HRP20010496A2
HRP20010496A2 HR20010496A HRP20010496A HRP20010496A2 HR P20010496 A2 HRP20010496 A2 HR P20010496A2 HR 20010496 A HR20010496 A HR 20010496A HR P20010496 A HRP20010496 A HR P20010496A HR P20010496 A2 HRP20010496 A2 HR P20010496A2
Authority
HR
Croatia
Prior art keywords
nucleoside
stimulus
cells
ribavirin
immune system
Prior art date
Application number
HR20010496A
Other languages
English (en)
Croatian (hr)
Inventor
Robert Tam
Original Assignee
Icn Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icn Pharmaceuticals filed Critical Icn Pharmaceuticals
Publication of HRP20010496A2 publication Critical patent/HRP20010496A2/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Obesity (AREA)
  • AIDS & HIV (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HR20010496A 1999-01-29 1999-12-20 Modulation of immune response by ribavirin HRP20010496A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24136799A 1999-01-29 1999-01-29
PCT/US1999/030490 WO2000044388A1 (en) 1999-01-29 1999-12-20 Modulation of immune response by ribavirin

Publications (1)

Publication Number Publication Date
HRP20010496A2 true HRP20010496A2 (en) 2003-08-31

Family

ID=22910442

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20010496A HRP20010496A2 (en) 1999-01-29 1999-12-20 Modulation of immune response by ribavirin

Country Status (20)

Country Link
EP (1) EP1146883A4 (de)
JP (1) JP2002535371A (de)
KR (1) KR20020023939A (de)
CN (1) CN1334736A (de)
AU (1) AU2483300A (de)
BR (1) BR9917090A (de)
CA (1) CA2357735A1 (de)
CZ (1) CZ20012519A3 (de)
HK (1) HK1040937A1 (de)
HR (1) HRP20010496A2 (de)
HU (1) HUP0200027A2 (de)
IL (1) IL144130A0 (de)
MX (1) MXPA01007211A (de)
NO (1) NO20013529L (de)
PL (1) PL364699A1 (de)
RU (1) RU2211698C2 (de)
SI (1) SI20802A (de)
SK (1) SK10092001A3 (de)
WO (1) WO2000044388A1 (de)
ZA (1) ZA200105595B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001292151B2 (en) 2000-08-17 2006-05-04 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US20050182252A1 (en) 2004-02-13 2005-08-18 Reddy K. R. Novel 2'-C-methyl nucleoside derivatives
WO2007104070A1 (en) * 2006-03-14 2007-09-20 Wholesome Biopharm Pty Ltd Method and composition for treating allergic diseases
WO2009022236A2 (en) 2007-08-16 2009-02-19 Tripep Ab Immunogen platform

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211771A (en) * 1971-06-01 1980-07-08 Robins Ronald K Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
EP0038629A1 (de) * 1980-04-17 1981-10-28 Beecham Group Plc Virazol-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als antivirale Mittel
BE902199A (fr) * 1984-10-29 1985-07-31 Vira Tek Inc Procede de traitement medical de maladies virales utilisant le 1-beta-d-ribofurannosyl-1, 2,4-triazole-3-carboxamide.
ATE135914T1 (de) * 1986-03-27 1996-04-15 Gensia Inc Aica riboside zur prophylaktischen behandlung von krankheiten mit einer verminderten durchblutung.
US5030623A (en) * 1986-03-27 1991-07-09 The Regents Of The University Of California Methods for increasing extracellular adenosine and for stabilizing mast cells
US5405837A (en) * 1993-05-18 1995-04-11 Indiana University Foundation Method for the treatment of neoplastic disease utilizing tiazofurin and ribavirin
RU2088232C1 (ru) * 1995-02-14 1997-08-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Ингибитор репродукции вируса марбург
PT879056E (pt) * 1996-01-23 2002-10-31 Ribapharm Inc Modulacao da expressao das citocinas th1/th2 atraves de ribavirina em linfocitos t activados
US5767097A (en) * 1996-01-23 1998-06-16 Icn Pharmaceuticals, Inc. Specific modulation of Th1/Th2 cytokine expression by ribavirin in activated T-lymphocytes
AU738170B2 (en) * 1996-10-16 2001-09-13 Icn Pharmaceuticals, Inc. Monocyclic L-nucleosides, analogs and uses thereof

Also Published As

Publication number Publication date
JP2002535371A (ja) 2002-10-22
EP1146883A1 (de) 2001-10-24
CZ20012519A3 (cs) 2002-05-15
RU2211698C2 (ru) 2003-09-10
SK10092001A3 (sk) 2002-02-05
ZA200105595B (en) 2002-10-07
EP1146883A4 (de) 2004-11-24
WO2000044388A1 (en) 2000-08-03
HUP0200027A2 (en) 2002-04-29
CA2357735A1 (en) 2000-08-03
MXPA01007211A (es) 2002-05-06
HK1040937A1 (zh) 2002-06-28
SI20802A (sl) 2002-08-31
NO20013529D0 (no) 2001-07-17
CN1334736A (zh) 2002-02-06
KR20020023939A (ko) 2002-03-29
PL364699A1 (en) 2004-12-13
BR9917090A (pt) 2001-10-16
NO20013529L (no) 2001-09-12
AU2483300A (en) 2000-08-18
IL144130A0 (en) 2002-05-23

Similar Documents

Publication Publication Date Title
US6815542B2 (en) Nucleoside compounds and uses thereof
US6455508B1 (en) Methods for treating diseases with tirazole and pyrrolo-pyrimidine ribofuranosyl nucleosides
US6509320B1 (en) Purine L-nucleosides, analogs and uses thereof
CN1286258A (zh) 嘌呤l－核苷、其类似物及其用途
KR20030032927A (ko) 뉴클레오시드 화합물 및 이들의 용도
US6423695B1 (en) Cytokine related treatments of disease
WO2010065959A1 (en) Method of preparing adenosine-resistant anti-tumor t lymphocytes for adoptive immunotherapy
DE69712316T2 (de) Modulation der th1/th2 cytokinexpression durch ribavirin in aktivierten t-lymphozyten
US20020187945A1 (en) Modulation of immune response by ribavirin
RU2211698C2 (ru) Модуляция иммунного ответа с помощью рибавирина
CN1312254A (zh) 新的核苷
US7056895B2 (en) Tirazole nucleoside analogs and methods for using same
EP4157284A1 (de) Verwendung von nmn zur verringerung von immundepression und immunseneszenz
EP1132393B1 (de) L-Ribavirin und dessen Verwendung
Asano et al. Immunostimulatory therapy with anti-CD3 monoclonal antibodies and recombinant interleukin-2: heightened in vivo expression of mRNA encoding cytotoxic attack molecules and immunoregulatory cytokines and regression of murine renal cell carcinoma
NZ512879A (en) Modulation of immune response by Ribavirin
DE29924200U1 (de) Modulation einer Immunantwort durch Ribavirin
Upjohn Company Cytarabine (Cytosar)
EP1277759A1 (de) Behandlungen von Zytokin-bedingten Krankheiten
CN1817349A (zh) 具有甲脒修饰的单环碱基的核苷类似物
CN1494912A (zh) 细胞因子相关的疾病治疗法
NZ505553A (en) 8-substituted alpha or beta L-guanosine analogs and uses thereof
HK1052937A1 (en) Cytokine related treatments of disease
HK1038365A1 (en) L-ribavirin and uses thereof

Legal Events

Date Code Title Description
A1OB Publication of a patent application
OBST Application withdrawn