HRP20020122A2 - Methods for crystallization of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine n-carboxyanhydride - Google Patents

Methods for crystallization of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine n-carboxyanhydride Download PDF

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Publication number
HRP20020122A2
HRP20020122A2 HR20020122A HRP20020122A HRP20020122A2 HR P20020122 A2 HRP20020122 A2 HR P20020122A2 HR 20020122 A HR20020122 A HR 20020122A HR P20020122 A HRP20020122 A HR P20020122A HR P20020122 A2 HRP20020122 A2 HR P20020122A2
Authority
HR
Croatia
Prior art keywords
solvent
solution
process according
good solvent
crystallization process
Prior art date
Application number
HR20020122A
Other languages
English (en)
Croatian (hr)
Inventor
Masafumi Fukae
Yasuyoshi Ueda
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corp filed Critical Kaneka Corp
Publication of HRP20020122A2 publication Critical patent/HRP20020122A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
HR20020122A 2000-05-15 2001-05-15 Methods for crystallization of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine n-carboxyanhydride HRP20020122A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000141717 2000-05-15
JP2000330339 2000-10-30
JP2000352892 2000-11-20
PCT/JP2001/004059 WO2001087858A1 (en) 2000-05-15 2001-05-15 Methods for crystallization of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine n-carboxyanhydride

Publications (1)

Publication Number Publication Date
HRP20020122A2 true HRP20020122A2 (en) 2003-04-30

Family

ID=27343377

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020122A HRP20020122A2 (en) 2000-05-15 2001-05-15 Methods for crystallization of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine n-carboxyanhydride

Country Status (17)

Country Link
US (1) US6784310B2 (cs)
EP (1) EP1283204B1 (cs)
JP (1) JP4149706B2 (cs)
KR (1) KR100527648B1 (cs)
CN (1) CN1184213C (cs)
AT (1) ATE423106T1 (cs)
AU (1) AU5675801A (cs)
CZ (1) CZ2002532A3 (cs)
DE (1) DE60137686D1 (cs)
ES (1) ES2320413T3 (cs)
HR (1) HRP20020122A2 (cs)
HU (1) HUP0202516A3 (cs)
IS (1) IS6224A (cs)
PL (1) PL351841A1 (cs)
SI (1) SI20817A (cs)
TW (1) TW527351B (cs)
WO (1) WO2001087858A1 (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1659145B2 (en) 2003-08-29 2016-06-08 Sekisui Plastics Co., Ltd. Pre-expanded particle of olefin-modified polystyrene resin, process for producing the same, and molded foam
JP4852282B2 (ja) * 2005-08-29 2012-01-11 保土谷化学工業株式会社 Ｎ−カルボン酸無水物の製造方法
CN101293887A (zh) * 2007-04-26 2008-10-29 中国科学院福建物质结构研究所 一种高纯度环状硫酸酯的纯化方法
JP2011016790A (ja) 2009-06-08 2011-01-27 Sumitomo Chemical Co Ltd ピラゾリノン誘導体の精製方法
WO2014202659A1 (en) 2013-06-21 2014-12-24 Sanofi-Aventis Deutschland Gmbh Process for the preparation of amides of n-[1-(s)-(ethoxycarbonyl)-3-phenylpropyl]-l-alanine
US12435048B2 (en) 2018-09-28 2025-10-07 Lonza Ltd Method for preparation of n-carboxyanhydrides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4831184A (en) * 1981-03-30 1989-05-16 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
US4496542A (en) * 1981-03-30 1985-01-29 Usv Pharmaceutical Corporation N-substituted-amido-amino acids
JPS6248696A (ja) 1985-08-27 1987-03-03 Kanegafuchi Chem Ind Co Ltd Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニル−ｌ−プロリンの製造法
SI9200213A (en) 1992-09-16 1994-03-31 Krka Process for preparing alkyl-l-alanil-l-proline derivates
HU215699B (hu) 1992-11-13 1999-02-01 E. I. Du Pont De Nemours And Co. Eljárás 2,4-oxazolidin-dionok és intermedierjeik előállítására
IN184759B (cs) * 1997-07-22 2000-09-23 Kaneka Corp
JP4505917B2 (ja) 1999-01-22 2010-07-21 田辺三菱製薬株式会社 新規微生物およびそれを用いるｌ−アミノ酸の製法

Also Published As

Publication number Publication date
PL351841A1 (en) 2003-06-16
DE60137686D1 (de) 2009-04-02
CN1380881A (zh) 2002-11-20
HUP0202516A3 (en) 2003-04-28
KR100527648B1 (ko) 2005-11-09
WO2001087858A1 (en) 2001-11-22
EP1283204B1 (en) 2009-02-18
ATE423106T1 (de) 2009-03-15
IS6224A (is) 2002-01-09
CZ2002532A3 (cs) 2002-05-15
EP1283204A1 (en) 2003-02-12
EP1283204A4 (en) 2007-09-05
US20020137944A1 (en) 2002-09-26
ES2320413T3 (es) 2009-05-22
US6784310B2 (en) 2004-08-31
JP4149706B2 (ja) 2008-09-17
TW527351B (en) 2003-04-11
HUP0202516A2 (hu) 2003-01-28
SI20817A (sl) 2002-08-31
KR20020038689A (ko) 2002-05-23
CN1184213C (zh) 2005-01-12
AU5675801A (en) 2001-11-26

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