IS6224A - Aðferð til kristöllunar N- (1(S)-etoxýkarbonýl-3-fenýlprópýl)-L-alanín-N-karboxýlanhýdríðs - Google Patents

Aðferð til kristöllunar N- (1(S)-etoxýkarbonýl-3-fenýlprópýl)-L-alanín-N-karboxýlanhýdríðs

Info

Publication number
IS6224A
IS6224A IS6224A IS6224A IS6224A IS 6224 A IS6224 A IS 6224A IS 6224 A IS6224 A IS 6224A IS 6224 A IS6224 A IS 6224A IS 6224 A IS6224 A IS 6224A
Authority
IS
Iceland
Prior art keywords
phenylpropyl
ethoxycarbonyl
alanine
carboxylanhydride
crystallizing
Prior art date
Application number
IS6224A
Other languages
English (en)
Inventor
Fukae Masafumi
Ueda Yasuyoshi
Original Assignee
Kaneka Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corporation filed Critical Kaneka Corporation
Publication of IS6224A publication Critical patent/IS6224A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
IS6224A 2000-05-15 2002-01-09 Aðferð til kristöllunar N- (1(S)-etoxýkarbonýl-3-fenýlprópýl)-L-alanín-N-karboxýlanhýdríðs IS6224A (is)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000141717 2000-05-15
JP2000330339 2000-10-30
JP2000352892 2000-11-20
PCT/JP2001/004059 WO2001087858A1 (en) 2000-05-15 2001-05-15 Methods for crystallization of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine n-carboxyanhydride

Publications (1)

Publication Number Publication Date
IS6224A true IS6224A (is) 2002-01-09

Family

ID=27343377

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6224A IS6224A (is) 2000-05-15 2002-01-09 Aðferð til kristöllunar N- (1(S)-etoxýkarbonýl-3-fenýlprópýl)-L-alanín-N-karboxýlanhýdríðs

Country Status (17)

Country Link
US (1) US6784310B2 (is)
EP (1) EP1283204B1 (is)
JP (1) JP4149706B2 (is)
KR (1) KR100527648B1 (is)
CN (1) CN1184213C (is)
AT (1) ATE423106T1 (is)
AU (1) AU5675801A (is)
CZ (1) CZ2002532A3 (is)
DE (1) DE60137686D1 (is)
ES (1) ES2320413T3 (is)
HR (1) HRP20020122A2 (is)
HU (1) HUP0202516A3 (is)
IS (1) IS6224A (is)
PL (1) PL351841A1 (is)
SI (1) SI20817A (is)
TW (1) TW527351B (is)
WO (1) WO2001087858A1 (is)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100487029C (zh) 2003-08-29 2009-05-13 积水化成品工业株式会社 聚烯烃系树脂改性的聚苯乙烯系树脂的预发泡粒子及其制备方法和发泡成形体
JP4852282B2 (ja) * 2005-08-29 2012-01-11 保土谷化学工業株式会社 Ｎ−カルボン酸無水物の製造方法
CN101293887A (zh) * 2007-04-26 2008-10-29 中国科学院福建物质结构研究所 一种高纯度环状硫酸酯的纯化方法
JP2011016790A (ja) 2009-06-08 2011-01-27 Sumitomo Chemical Co Ltd ピラゾリノン誘導体の精製方法
WO2014202659A1 (en) 2013-06-21 2014-12-24 Sanofi-Aventis Deutschland Gmbh Process for the preparation of amides of n-[1-(s)-(ethoxycarbonyl)-3-phenylpropyl]-l-alanine
WO2020064904A1 (en) 2018-09-28 2020-04-02 Lonza Ltd Method for preparation of n-carboxyanhydrides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496542A (en) 1981-03-30 1985-01-29 Usv Pharmaceutical Corporation N-substituted-amido-amino acids
US4831184A (en) * 1981-03-30 1989-05-16 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
JPS6248696A (ja) 1985-08-27 1987-03-03 Kanegafuchi Chem Ind Co Ltd Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニル−ｌ−プロリンの製造法
SI9200213A (en) 1992-09-16 1994-03-31 Krka Process for preparing alkyl-l-alanil-l-proline derivates
EP0668859B1 (en) 1992-11-13 1997-02-26 E.I. Du Pont De Nemours And Company Processes for preparing 2,4-oxazolidinediones
IN184759B (is) * 1997-07-22 2000-09-23 Kaneka Corp
JP4505917B2 (ja) 1999-01-22 2010-07-21 田辺三菱製薬株式会社 新規微生物およびそれを用いるｌ−アミノ酸の製法

Also Published As

Publication number Publication date
HUP0202516A3 (en) 2003-04-28
HUP0202516A2 (hu) 2003-01-28
HRP20020122A2 (en) 2003-04-30
PL351841A1 (en) 2003-06-16
CZ2002532A3 (cs) 2002-05-15
EP1283204A4 (en) 2007-09-05
KR20020038689A (ko) 2002-05-23
ATE423106T1 (de) 2009-03-15
WO2001087858A1 (en) 2001-11-22
AU5675801A (en) 2001-11-26
KR100527648B1 (ko) 2005-11-09
SI20817A (sl) 2002-08-31
EP1283204A1 (en) 2003-02-12
CN1380881A (zh) 2002-11-20
EP1283204B1 (en) 2009-02-18
DE60137686D1 (de) 2009-04-02
JP4149706B2 (ja) 2008-09-17
TW527351B (en) 2003-04-11
US6784310B2 (en) 2004-08-31
ES2320413T3 (es) 2009-05-22
US20020137944A1 (en) 2002-09-26
CN1184213C (zh) 2005-01-12

Similar Documents

Publication Publication Date Title
LV10575A (lv) Izoksazoi-4-karbonskabes amids un hidroksialkiliden-cianetikskabes amids sos savienojumus saturosi astniecibas lidzekli un to pielietojums
UY24864A1 (es) Metodo para preparar y purificar un derivado n-alcohilado de aspartamo
DE69623444D1 (de) Substituierte isoxazole zur behandlung von entzündung
HK1049165A1 (zh) 循环β-氨基酸衍生物作为质基金属蛋白酶及TNF-α的抑制剂
HUT77344A (hu) Orto-szubsztituált-benzol- és -piridin-származékok, és az ezeket tartalmazó gyógyszerkészítmények
EA200200510A1 (ru) 4-карбоксиамино-2-этил-1,2,3,4-тетрагидрохинолин в кристаллической форме как ингибитор сетр
Holzapfel et al. Antineoplastic agents. Par 108. Structural biochemistry. Part 23. Synthesis of the dolastatin thiazole amino acid component (gln) Thz
ATE288446T1 (de) Herstellung von n-(n-(3,3-dimethylbutyl)-l-alpha- aspartyl)- l-phenylalaninmethylester mittels oxazolidinonderivate
HUP9802488A2 (hu) Eljárás Kathepszin K gátlására
IS6224A (is) Aðferð til kristöllunar N- (1(S)-etoxýkarbonýl-3-fenýlprópýl)-L-alanín-N-karboxýlanhýdríðs
AR048279A1 (es) La forma ii cristalina de cabergolina
DK0868429T3 (da) Oligopeptidforbindelser indeholdende D-2-alkyltryptophan hvilke er i stand til at fremme frigivelsen af væksthormon
Donkor et al. Synthesis of a reported calpain inhibitor isolated from Streptomyces griseus
EP1468997A3 (en) Polymorphous forms of rosiglitazone maleate
ATE248806T1 (de) N-3, 3-dimethylbutyl-l-asparaginsäure und ihre ester, verfahren zur herstellung dieser und das verfahren um daraus n-(n-(3,3-dimethylbutyl)-l- alpha-aspartyl)-l-phenylalanin-1-methylester herzustellen
DE50207212D1 (de) Verfahren zur herstellung von 2-pyrrolidon
JPS5363375A (en) Preparation of substd. benzoic acid amide derivatives
DE60019723D1 (de) Eine methode zur herstellung von verbindungen der formel 1 und derivaten
Isowa et al. Acylation of N δ-Benzyloxyornithine
BR9813595A (pt) Cristal misto, processo para produzir o mesmo, e, adoçante
BR9914826A (pt) Processo de cristalização de cristais de éster metìlico de n- [n-(3,3-dimetilbutil)-l-alfa-aspartil] -l-fenilalanina
HUP0004149A2 (hu) Eljárás N-[1(S)-etoxi-karbonil-3-fenil-propil]-L-alanil-L-prolin maleát só kristályosítására
JPS5419966A (en) Production of pyroglutamine peptide
WO2001030759A3 (en) Sodium-hydrogen exchanger type 1 inhibitor crystals
ATE282046T1 (de) Herstellung von n-(n-(3,3-dimethylbutyl)-l-alpha- aspartlyl)-l-phenylalaninmethylester mittels reduktiver alkylation und crystallisierung im wässrigen methanol