HRP20020599A2 - Corticotropin releasing factor antagonists - Google Patents
Corticotropin releasing factor antagonists Download PDFInfo
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- HRP20020599A2 HRP20020599A2 HR20020599A HRP20020599A HRP20020599A2 HR P20020599 A2 HRP20020599 A2 HR P20020599A2 HR 20020599 A HR20020599 A HR 20020599A HR P20020599 A HRP20020599 A HR P20020599A HR P20020599 A2 HRP20020599 A2 HR P20020599A2
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- alkyl
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- phenoxy
- cycloalkyl
- dimethyl
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- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17661100P | 2000-01-18 | 2000-01-18 | |
| PCT/IB2001/000004 WO2001053263A1 (fr) | 2000-01-18 | 2001-01-05 | Antagonistes de la corticoliberine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20020599A2 true HRP20020599A2 (en) | 2004-08-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20020599A HRP20020599A2 (en) | 2000-01-18 | 2001-01-05 | Corticotropin releasing factor antagonists |
Country Status (36)
| Country | Link |
|---|---|
| US (1) | US6833378B2 (fr) |
| EP (1) | EP1263732A1 (fr) |
| JP (1) | JP2003520272A (fr) |
| KR (1) | KR20020063934A (fr) |
| CN (1) | CN1395566A (fr) |
| AP (1) | AP2002002583A0 (fr) |
| AR (1) | AR027221A1 (fr) |
| AU (1) | AU779995B2 (fr) |
| BG (1) | BG106853A (fr) |
| BR (1) | BR0107662A (fr) |
| CA (1) | CA2397633A1 (fr) |
| CO (1) | CO5271658A1 (fr) |
| CR (1) | CR6698A (fr) |
| CZ (1) | CZ20022390A3 (fr) |
| EA (2) | EA200200688A1 (fr) |
| EE (1) | EE200200400A (fr) |
| GT (1) | GT200100007A (fr) |
| HN (1) | HN2001000006A (fr) |
| HR (1) | HRP20020599A2 (fr) |
| HU (1) | HUP0204272A3 (fr) |
| IL (1) | IL150632A0 (fr) |
| IS (1) | IS6445A (fr) |
| MA (1) | MA26864A1 (fr) |
| MX (1) | MXPA02007047A (fr) |
| NO (1) | NO20023424L (fr) |
| OA (1) | OA12157A (fr) |
| PA (1) | PA8510001A1 (fr) |
| PE (1) | PE20011166A1 (fr) |
| PL (1) | PL357589A1 (fr) |
| SK (1) | SK10062002A3 (fr) |
| SV (1) | SV2002000289A (fr) |
| TN (1) | TNSN01008A1 (fr) |
| UY (1) | UY26544A1 (fr) |
| WO (1) | WO2001053263A1 (fr) |
| YU (1) | YU54402A (fr) |
| ZA (1) | ZA200205660B (fr) |
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| US6956047B1 (en) * | 1995-06-06 | 2005-10-18 | Pfizer Inc. | Corticotropin releasing factor antagonists |
| EP1449532A1 (fr) * | 1999-08-27 | 2004-08-25 | Pfizer Products Inc. | Composé [2-(4-chloro-2,6-diméthyl-phénoxy)- 3,6-diméthyl-pyridin-4-yl] -(1-ethyl-propyl)- amine et utilisation comme CRF antagoniste |
| GB0117396D0 (en) | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
| GB0119249D0 (en) | 2001-08-07 | 2001-10-03 | Novartis Ag | Organic compounds |
| US7323469B2 (en) | 2001-08-07 | 2008-01-29 | Novartis Ag | 7H-pyrrolo[2,3-d]pyrimidine derivatives |
| AR040456A1 (es) | 2002-06-27 | 2005-04-06 | Bristol Myers Squibb Co | Piridina n-oxidos 2,4 -disubstituidos utiles como inhibidores de transcriptasa inversa del virus de inmunodeficiencia humana |
| EP2270006A1 (fr) * | 2002-08-08 | 2011-01-05 | Amgen, Inc | Dérivés de pyridazine en tant que ligands de récepteur vanilloïde |
| EP1688408A3 (fr) * | 2002-08-08 | 2007-08-22 | Amgen, Inc | Ligands du récepteur vanilloide et leur utilisation dans des traitements |
| CN102558155A (zh) | 2003-01-14 | 2012-07-11 | 阿伦纳药品公司 | 作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗 |
| ATE359782T1 (de) * | 2003-01-16 | 2007-05-15 | Sb Pharmco Inc | Heteroaryl-substituierte pyrrol(2, 3- b)pyridin- derivate als crf-rezeptor-antagonisten |
| GB0308208D0 (en) | 2003-04-09 | 2003-05-14 | Glaxo Group Ltd | Chemical compounds |
| US7030145B2 (en) | 2003-04-18 | 2006-04-18 | Bristol-Myers Squibb Company | Pyridinyl derivatives for the treatment of depression |
| US7112585B2 (en) | 2003-04-18 | 2006-09-26 | Bristol-Myers Squibb Company | Pyrimidine derivatives as corticotropin releasing factor inhibitors |
| AR045047A1 (es) | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| TWI335328B (en) | 2003-07-14 | 2011-01-01 | Arena Pharm Inc | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related hereto |
| US20050171095A1 (en) * | 2004-01-06 | 2005-08-04 | Pfizer Inc | Combination of CRF antagonists and 5-HT1B receptor antagonists |
| EP1701961A1 (fr) * | 2004-01-06 | 2006-09-20 | Taisho Pharmaceutical Co., Ltd | Derives de thienopyrimidine et de thienopyridine substitues par un groupe amino cyclique |
| MY139645A (en) | 2004-02-11 | 2009-10-30 | Amgen Inc | Vanilloid receptor ligands and their use in treatments |
| JP2007522233A (ja) | 2004-02-11 | 2007-08-09 | アムジエン・インコーポレーテツド | バニロイド受容体リガンド及び治療におけるそれらの使用 |
| AU2005238296A1 (en) | 2004-04-30 | 2005-11-10 | Warner-Lambert Company Llc | Substituted morpholine compounds for the treatment of central nervous system disorders |
| ATE460402T1 (de) * | 2004-05-12 | 2010-03-15 | Bristol Myers Squibb Co | Für die behandlung von thrombotischen leiden geeignete harnstoffantagonisten des p2y1- rezeptors |
| US20080167321A1 (en) | 2004-09-20 | 2008-07-10 | Xenon Pharmaceuticals Inc. | Pyridine Derivatives For Inhibiting Human Stearoyl-Coa-Desaturase |
| WO2006089311A1 (fr) | 2005-02-15 | 2006-08-24 | Amgen Inc. | Ligands des recepteurs vanilloides et leurs utilisations therapeutiques |
| US8153791B2 (en) | 2005-12-21 | 2012-04-10 | Janssen Pharmaceutica N.V. | Substituted pyrimidinyl oxime kinase inhibitors |
| WO2007109783A2 (fr) * | 2006-03-23 | 2007-09-27 | Janssen Pharmaceutica, N.V. | Inhibiteurs de pyrimidine kinase substituee |
| SI2076508T1 (sl) | 2006-10-18 | 2011-04-29 | Pfizer Prod Inc | Spojine biaril eter sečnine |
| WO2009144632A1 (fr) * | 2008-05-30 | 2009-12-03 | Pfizer Limited | Nouveaux composés |
| GB0913636D0 (en) * | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
| MX2013003184A (es) | 2010-09-22 | 2013-06-07 | Arena Pharm Inc | Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo. |
| CN105324376B (zh) | 2013-06-27 | 2017-06-23 | 辉瑞大药厂 | 杂芳族化合物及其作为多巴胺d1配体的用途 |
| AU2016205361C1 (en) | 2015-01-06 | 2021-04-08 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
| WO2016144703A1 (fr) | 2015-03-06 | 2016-09-15 | Pharmakea, Inc. | Inhibiteurs fluorés de la lysyl oxydase-like 2 et utilisations desdits inhibiteurs |
| WO2016144702A1 (fr) | 2015-03-06 | 2016-09-15 | Pharmakea, Inc. | Inhibiteurs de la lysyl oxydase-like 2 et utilisations desdits inhibiteurs |
| PL3310760T3 (pl) | 2015-06-22 | 2023-03-06 | Arena Pharmaceuticals, Inc. | Krystaliczna sól L-argininy kwasu (R)-2-(7-(4-cyklopentylo-3-(trifluorometylo)benzyloksy)- 1,2,3,4-tetrahydrocyklo-penta[b]indol-3-ilo)octowego do zastosowania w zaburzeniach związanych z receptorem S1P1 |
| EP3481829B1 (fr) * | 2016-07-08 | 2021-04-07 | H. Hoffnabb-La Roche Ag | Dérivés fusionnés de pyrimidine |
| KR102571296B1 (ko) * | 2016-09-07 | 2023-08-28 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | P-tau를 감소시키고 인지를 개선하는 알로스테릭 코르티코트로핀-방출 인자 수용체 1 (crfr1) 길항제 |
| MX390964B (es) | 2016-09-07 | 2025-03-21 | Pharmakea Inc | Formas cristalinas de un inhibidor tipo lisil oxidasa 2 y metodos de realizacion. |
| MX2019002612A (es) | 2016-09-07 | 2019-08-21 | Pharmakea Inc | Usos de un inhibidor de lisil-oxidasa tipo 2. |
| KR20190116416A (ko) | 2017-02-16 | 2019-10-14 | 아레나 파마슈티칼스, 인크. | 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법 |
| LT3609868T (lt) | 2017-03-13 | 2023-12-11 | Raqualia Pharma Inc. | Tetrahidrochinolino dariniai kaip p2x7 receptoriaus antagonistai |
| AU2019280822A1 (en) | 2018-06-06 | 2021-01-07 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
| WO2020168068A1 (fr) * | 2019-02-13 | 2020-08-20 | The University Of Vermont And State Agricultural College | Antagoniste des récepteurs du pacap de type petite molécule et ses utilisations |
| JP7493835B2 (ja) * | 2019-11-06 | 2024-06-03 | アルベルト・アインシュタイン・カレッジ・オブ・メディシン | 小分子プロスタグラジン輸送阻害剤 |
| EP4604945A2 (fr) * | 2022-10-18 | 2025-08-27 | Merck Sharp & Dohme LLC | Nouveaux modulateurs de canaux kv3 |
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| DE3145287A1 (de) | 1981-11-14 | 1983-05-19 | Troponwerke GmbH & Co KG, 5000 Köln | Pyrrolo (2.3-d)pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4605642A (en) | 1984-02-23 | 1986-08-12 | The Salk Institute For Biological Studies | CRF antagonists |
| EP0264883A3 (fr) | 1986-10-21 | 1990-04-04 | Banyu Pharmaceutical Co., Ltd. | Dérivés de la pyridine substitués |
| US5063245A (en) | 1990-03-28 | 1991-11-05 | Nova Pharmaceutical Corporation | Corticotropin-releasing factor antagonism compounds |
| AU647822B2 (en) | 1990-09-14 | 1994-03-31 | Marion Merrell Dow Inc. | Novel carbocyclic adenosine analogs useful as immunosuppressants |
| ES2092182T3 (es) | 1992-08-10 | 1996-11-16 | Volkswagen Ag | Dispositivo de cambio para una caja de cambios. |
| ES2128544T3 (es) * | 1992-12-17 | 1999-05-16 | Pfizer | Pirrolopirimidinas como antagonistas del crf. |
| JP3398152B2 (ja) * | 1993-10-12 | 2003-04-21 | ブリストル‐マイヤーズ・スクイブ・ファーマ・カンパニー | 1n−アルキル−n−アリールピリミジンアミンおよびその誘導体 |
| TW574214B (en) * | 1994-06-08 | 2004-02-01 | Pfizer | Corticotropin releasing factor antagonists |
| US5691364A (en) | 1995-03-10 | 1997-11-25 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| US6403599B1 (en) * | 1995-11-08 | 2002-06-11 | Pfizer Inc | Corticotropin releasing factor antagonists |
| PA8467401A1 (es) * | 1998-02-17 | 2000-09-29 | Pfizer Prod Inc | Procedimiento para tratar la insuficiencia cardiaca |
| US6130188A (en) * | 1998-05-05 | 2000-10-10 | American Cyanamid Company | Herbicidal pyridine compounds |
| EP1040831A3 (fr) * | 1999-04-02 | 2003-05-02 | Pfizer Products Inc. | Utilisation d'antagonistes du facteur de libération de la corticotropine pour la prévention de la mort subite |
| US6387894B1 (en) * | 1999-06-11 | 2002-05-14 | Pfizer Inc. | Use of CRF antagonists and renin-angiotensin system inhibitors |
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- 2001-01-05 HU HU0204272A patent/HUP0204272A3/hu unknown
- 2001-01-05 BR BR0107662-0A patent/BR0107662A/pt not_active IP Right Cessation
- 2001-01-05 WO PCT/IB2001/000004 patent/WO2001053263A1/fr not_active Ceased
- 2001-01-05 EA EA200200688A patent/EA200200688A1/ru unknown
- 2001-01-05 KR KR1020027009229A patent/KR20020063934A/ko not_active Ceased
- 2001-01-05 YU YU54402A patent/YU54402A/sh unknown
- 2001-01-05 CZ CZ20022390A patent/CZ20022390A3/cs unknown
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- 2001-01-05 AP APAP/P/2002/002583A patent/AP2002002583A0/en unknown
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- 2001-01-05 EA EA200300834A patent/EA200300834A1/ru unknown
- 2001-01-05 JP JP2001553267A patent/JP2003520272A/ja active Pending
- 2001-01-05 EP EP01900209A patent/EP1263732A1/fr not_active Withdrawn
- 2001-01-05 SK SK1006-2002A patent/SK10062002A3/sk unknown
- 2001-01-05 IL IL15063201A patent/IL150632A0/xx unknown
- 2001-01-05 OA OA1200200206A patent/OA12157A/en unknown
- 2001-01-05 CA CA002397633A patent/CA2397633A1/fr not_active Abandoned
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- 2001-01-05 PL PL01357589A patent/PL357589A1/xx not_active Application Discontinuation
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- 2001-01-17 US US09/761,995 patent/US6833378B2/en not_active Expired - Fee Related
- 2001-01-17 TN TNTNSN01008A patent/TNSN01008A1/fr unknown
- 2001-01-17 GT GT200100007A patent/GT200100007A/es unknown
- 2001-01-17 CO CO01003117A patent/CO5271658A1/es not_active Application Discontinuation
- 2001-01-18 UY UY26544A patent/UY26544A1/es not_active Application Discontinuation
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- 2002-06-25 IS IS6445A patent/IS6445A/is unknown
- 2002-07-08 CR CR6698A patent/CR6698A/es not_active Application Discontinuation
- 2002-07-11 MA MA26728A patent/MA26864A1/fr unknown
- 2002-07-16 ZA ZA200205660A patent/ZA200205660B/en unknown
- 2002-07-17 NO NO20023424A patent/NO20023424L/no not_active Application Discontinuation
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