HRP20040202A2 - Tieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity - Google Patents

Tieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity Download PDF

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Publication number
HRP20040202A2
HRP20040202A2 HR20040202A HRP20040202A HRP20040202A2 HR P20040202 A2 HRP20040202 A2 HR P20040202A2 HR 20040202 A HR20040202 A HR 20040202A HR P20040202 A HRP20040202 A HR P20040202A HR P20040202 A2 HRP20040202 A2 HR P20040202A2
Authority
HR
Croatia
Prior art keywords
pyrimidine
thieno
methylthio
amino
tert
Prior art date
Application number
HR20040202A
Other languages
English (en)
Croatian (hr)
Inventor
Robert Gerard Jules Ma Hanssen
Cornelis Marius Timmers
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of HRP20040202A2 publication Critical patent/HRP20040202A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR20040202A 2001-09-04 2002-08-29 Tieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity HRP20040202A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01203327 2001-09-04
PCT/EP2002/009647 WO2003020726A1 (en) 2001-09-04 2002-08-29 Thieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity

Publications (1)

Publication Number Publication Date
HRP20040202A2 true HRP20040202A2 (en) 2004-08-31

Family

ID=8180876

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040202A HRP20040202A2 (en) 2001-09-04 2002-08-29 Tieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity

Country Status (28)

Country Link
US (1) US7317006B2 (is)
EP (1) EP1427733B1 (is)
JP (1) JP4262092B2 (is)
KR (1) KR100900018B1 (is)
CN (1) CN1246324C (is)
AR (1) AR036407A1 (is)
AT (1) ATE345345T1 (is)
AU (1) AU2002337035B2 (is)
BR (1) BR0211938A (is)
CA (1) CA2456901C (is)
CY (1) CY1106012T1 (is)
DE (1) DE60216128T2 (is)
DK (1) DK1427733T3 (is)
ES (1) ES2275005T3 (is)
HR (1) HRP20040202A2 (is)
HU (1) HUP0401444A3 (is)
IL (1) IL160084A0 (is)
IS (1) IS2424B (is)
MX (1) MXPA04002045A (is)
NO (1) NO20040927L (is)
NZ (1) NZ531340A (is)
PE (1) PE20030439A1 (is)
PL (1) PL368502A1 (is)
PT (1) PT1427733E (is)
RU (1) RU2298011C2 (is)
TW (1) TWI228508B (is)
WO (1) WO2003020726A1 (is)
ZA (1) ZA200401455B (is)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890923B2 (en) * 2002-12-16 2005-05-10 Astrazeneca Ab Compounds
GB0315950D0 (en) * 2003-06-11 2003-08-13 Xention Discovery Ltd Compounds
GB0525164D0 (en) * 2005-12-09 2006-01-18 Xention Discovery Ltd Compounds
CN100430403C (zh) * 2006-10-13 2008-11-05 中国科学院上海有机化学研究所 3-芳基-5,6-取代噻吩并嘧啶-4-羰基-2-巯基乙腈、合成方法和用途
US20090118276A1 (en) * 2007-11-02 2009-05-07 Wyeth Thienopyrimidines, thienopyridines, and pyrrolopyrimidines as b-raf inhibitors
TWI389913B (zh) * 2008-09-08 2013-03-21 Lg Life Sciences Ltd 并合雜環化合物
US8741259B2 (en) * 2008-10-20 2014-06-03 Marvin C. Gershengorn Low molecular weight thyroid stimulating hormone receptor (TSHR) agonists
GB0905525D0 (en) 2009-03-31 2009-05-13 Univ Leiden Compounds and uses
EA022553B1 (ru) 2010-01-22 2016-01-29 Байер Интеллектуэль Проперти Гмбх Применение комбинации биологически активных веществ, набор и средство, содержащие комбинацию биологически активных веществ, для борьбы с вредителями животного происхождения и способ улучшения использования продукционного потенциала трансгенного растения
EP2563777A4 (en) 2010-04-08 2013-09-04 Us Health INVERSE AGONISTS AND NEUTRAL AGONISTS FOR THE TSH RECEPTOR
WO2016029375A1 (en) 2014-08-27 2016-03-03 The Procter & Gamble Company Wearable article having elastic belt
WO2016029372A1 (en) 2014-08-27 2016-03-03 The Procter & Gamble Company Wearable article having elastic belt
RU2619091C2 (ru) * 2015-10-13 2017-05-11 Министерство Промышленности И Торговли Рф Цилиндрический термоэмиссионный катод
CN108883011B (zh) 2016-04-08 2021-05-07 宝洁公司 具有艺术作品的可穿着制品
AU2023282849A1 (en) * 2022-06-08 2025-01-09 Icahn School Of Medicine At Mount Sinai Method of treating obesity with a luteinizing hormone receptor agonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2054784T3 (es) 1987-08-08 1994-08-16 Akzo Nv Un metodo para la fabricacion de un implante.
TW564247B (en) * 1999-04-08 2003-12-01 Akzo Nobel Nv Bicyclic heteraromatic compound

Also Published As

Publication number Publication date
MXPA04002045A (es) 2004-07-08
US7317006B2 (en) 2008-01-08
AU2002337035B2 (en) 2008-04-24
WO2003020726A1 (en) 2003-03-13
EP1427733B1 (en) 2006-11-15
IL160084A0 (en) 2004-06-20
TWI228508B (en) 2005-03-01
KR20040029134A (ko) 2004-04-03
CA2456901A1 (en) 2003-03-13
IS7130A (is) 2004-01-29
KR100900018B1 (ko) 2009-06-01
HUP0401444A2 (hu) 2004-11-29
JP2005505555A (ja) 2005-02-24
PL368502A1 (en) 2005-04-04
NZ531340A (en) 2005-08-26
NO20040927L (no) 2004-03-03
DK1427733T3 (da) 2007-03-19
PT1427733E (pt) 2007-02-28
CN1246324C (zh) 2006-03-22
ES2275005T3 (es) 2007-06-01
US20040180873A1 (en) 2004-09-16
DE60216128D1 (de) 2006-12-28
RU2298011C2 (ru) 2007-04-27
HUP0401444A3 (en) 2008-05-28
ATE345345T1 (de) 2006-12-15
JP4262092B2 (ja) 2009-05-13
DE60216128T2 (de) 2007-09-27
BR0211938A (pt) 2004-09-21
CY1106012T1 (el) 2011-04-06
CN1551884A (zh) 2004-12-01
CA2456901C (en) 2011-01-04
AR036407A1 (es) 2004-09-08
EP1427733A1 (en) 2004-06-16
ZA200401455B (en) 2004-11-19
IS2424B (is) 2008-10-15
PE20030439A1 (es) 2003-05-17
RU2004110042A (ru) 2005-08-20

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Owner name: N.V. ORGANON, NL

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