IS7130A - Þénó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni - Google Patents

Þénó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni

Info

Publication number: IS7130A
Authority: IS; Iceland
Prior art keywords: pyrimidine; theno; combined; agonist activity; fsh agonist
Prior art date: 2001-09-04

Application number

IS7130A

Other languages

English (en)

Other versions

IS2424B (is

Inventor

Gerard Jules Marie Hanssen Robert

Marius Timmers Cornelis

Original Assignee

Akzo Nobel N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-04

Filing date

2004-01-29

Publication date

2004-01-29

2004-01-29 Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.

2004-01-29 Publication of IS7130A publication Critical patent/IS7130A/is

2008-10-15 Publication of IS2424B publication Critical patent/IS2424B/is

Links

CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
239000000556 agonist Substances 0.000 title 1
102000008175 FSH Receptors Human genes 0.000 abstract 1
108010060374 FSH Receptors Proteins 0.000 abstract 1
102000023108 LH Receptors Human genes 0.000 abstract 1
108010011942 LH Receptors Proteins 0.000 abstract 1
230000003213 activating effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000035558 fertility Effects 0.000 abstract 1
125000000592 heterocycloalkyl group Chemical group 0.000 abstract 1
230000001105 regulatory effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1
DDWBRNXDKNIQDY-UHFFFAOYSA-N thieno[2,3-d]pyrimidine Chemical class N1=CN=C2SC=CC2=C1 DDWBRNXDKNIQDY-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IS7130A 2001-09-04 2004-01-29 Þíenó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni IS2424B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01203327		2001-09-04
PCT/EP2002/009647 WO2003020726A1 (en)	2001-09-04	2002-08-29	Thieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity

Publications (2)

Publication Number	Publication Date
IS7130A true IS7130A (is)	2004-01-29
IS2424B IS2424B (is)	2008-10-15

Family

ID=8180876

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7130A IS2424B (is)	2001-09-04	2004-01-29	Þíenó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni

Country Status (28)

Country	Link
US (1)	US7317006B2 (is)
EP (1)	EP1427733B1 (is)
JP (1)	JP4262092B2 (is)
KR (1)	KR100900018B1 (is)
CN (1)	CN1246324C (is)
AR (1)	AR036407A1 (is)
AT (1)	ATE345345T1 (is)
AU (1)	AU2002337035B2 (is)
BR (1)	BR0211938A (is)
CA (1)	CA2456901C (is)
CY (1)	CY1106012T1 (is)
DE (1)	DE60216128T2 (is)
DK (1)	DK1427733T3 (is)
ES (1)	ES2275005T3 (is)
HR (1)	HRP20040202A2 (is)
HU (1)	HUP0401444A3 (is)
IL (1)	IL160084A0 (is)
IS (1)	IS2424B (is)
MX (1)	MXPA04002045A (is)
NO (1)	NO20040927L (is)
NZ (1)	NZ531340A (is)
PE (1)	PE20030439A1 (is)
PL (1)	PL368502A1 (is)
PT (1)	PT1427733E (is)
RU (1)	RU2298011C2 (is)
TW (1)	TWI228508B (is)
WO (1)	WO2003020726A1 (is)
ZA (1)	ZA200401455B (is)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6890923B2 (en) *	2002-12-16	2005-05-10	Astrazeneca Ab	Compounds
GB0315950D0 (en) *	2003-06-11	2003-08-13	Xention Discovery Ltd	Compounds
GB0525164D0 (en) *	2005-12-09	2006-01-18	Xention Discovery Ltd	Compounds
CN100430403C (zh) *	2006-10-13	2008-11-05	中国科学院上海有机化学研究所	3-芳基-5,6-取代噻吩并嘧啶-4-羰基-2-巯基乙腈、合成方法和用途
US20090118276A1 (en) *	2007-11-02	2009-05-07	Wyeth	Thienopyrimidines, thienopyridines, and pyrrolopyrimidines as b-raf inhibitors
TWI389913B (zh) *	2008-09-08	2013-03-21	Lg Life Sciences Ltd	并合雜環化合物
EP2358684B8 (en)	2008-10-20	2014-10-22	The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services	Low molecular weight thyroid stimulating hormone receptor (tshr) agonists
GB0905525D0 (en)	2009-03-31	2009-05-13	Univ Leiden	Compounds and uses
NZ601341A (en)	2010-01-22	2014-02-28	Bayer Ip Gmbh	Acaricide and/or insecticide active substance combinations
CN102791705B (zh)	2010-04-08	2016-08-03	美国政府(由卫生和人类服务部的部长所代表)	用于tsh受体的反向激动剂和中性拮抗剂
WO2016029372A1 (en)	2014-08-27	2016-03-03	The Procter & Gamble Company	Wearable article having elastic belt
WO2016029375A1 (en)	2014-08-27	2016-03-03	The Procter & Gamble Company	Wearable article having elastic belt
RU2619091C2 (ru) *	2015-10-13	2017-05-11	Министерство Промышленности И Торговли Рф	Цилиндрический термоэмиссионный катод
CN108883011B (zh)	2016-04-08	2021-05-07	宝洁公司	具有艺术作品的可穿着制品
EP4536352A2 (en) *	2022-06-08	2025-04-16	Icahn School of Medicine at Mount Sinai	Method of treating obesity with a luteinizing hormone receptor agonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19975054I2 (de)	1987-08-08	2000-04-13	Akzo Nobel Nv	Kontrazeptives Implantat
TW564247B (en)	1999-04-08	2003-12-01	Akzo Nobel Nv	Bicyclic heteraromatic compound

2002
- 2002-07-22 TW TW091116284A patent/TWI228508B/zh not_active IP Right Cessation
- 2002-08-29 BR BR0211938-2A patent/BR0211938A/pt not_active IP Right Cessation
- 2002-08-29 CA CA2456901A patent/CA2456901C/en not_active Expired - Fee Related
- 2002-08-29 JP JP2003524996A patent/JP4262092B2/ja not_active Expired - Fee Related
- 2002-08-29 CN CNB028172604A patent/CN1246324C/zh not_active Expired - Fee Related
- 2002-08-29 PL PL02368502A patent/PL368502A1/xx not_active Application Discontinuation
- 2002-08-29 IL IL16008402A patent/IL160084A0/xx not_active IP Right Cessation
- 2002-08-29 AU AU2002337035A patent/AU2002337035B2/en not_active Ceased
- 2002-08-29 WO PCT/EP2002/009647 patent/WO2003020726A1/en not_active Ceased
- 2002-08-29 HU HU0401444A patent/HUP0401444A3/hu unknown
- 2002-08-29 DK DK02772230T patent/DK1427733T3/da active
- 2002-08-29 RU RU2004110042/04A patent/RU2298011C2/ru not_active IP Right Cessation
- 2002-08-29 HR HR20040202A patent/HRP20040202A2/hr not_active Application Discontinuation
- 2002-08-29 PT PT02772230T patent/PT1427733E/pt unknown
- 2002-08-29 EP EP02772230A patent/EP1427733B1/en not_active Expired - Lifetime
- 2002-08-29 DE DE60216128T patent/DE60216128T2/de not_active Expired - Lifetime
- 2002-08-29 KR KR1020047003095A patent/KR100900018B1/ko not_active Expired - Fee Related
- 2002-08-29 ES ES02772230T patent/ES2275005T3/es not_active Expired - Lifetime
- 2002-08-29 US US10/488,482 patent/US7317006B2/en not_active Expired - Lifetime
- 2002-08-29 MX MXPA04002045A patent/MXPA04002045A/es active IP Right Grant
- 2002-08-29 NZ NZ531340A patent/NZ531340A/en unknown
- 2002-08-29 AT AT02772230T patent/ATE345345T1/de not_active IP Right Cessation
- 2002-09-02 AR ARP020103309A patent/AR036407A1/es unknown
- 2002-09-03 PE PE2002000840A patent/PE20030439A1/es not_active Application Discontinuation
2004
- 2004-01-29 IS IS7130A patent/IS2424B/is unknown
- 2004-02-23 ZA ZA200401455A patent/ZA200401455B/en unknown
- 2004-03-03 NO NO20040927A patent/NO20040927L/no not_active Application Discontinuation
2007
- 2007-02-13 CY CY20071100189T patent/CY1106012T1/el unknown

Also Published As

Publication number	Publication date
JP2005505555A (ja)	2005-02-24
CA2456901A1 (en)	2003-03-13
JP4262092B2 (ja)	2009-05-13
WO2003020726A1 (en)	2003-03-13
HRP20040202A2 (en)	2004-08-31
IS2424B (is)	2008-10-15
AU2002337035B2 (en)	2008-04-24
IL160084A0 (en)	2004-06-20
DE60216128D1 (de)	2006-12-28
MXPA04002045A (es)	2004-07-08
BR0211938A (pt)	2004-09-21
DK1427733T3 (da)	2007-03-19
CY1106012T1 (el)	2011-04-06
ATE345345T1 (de)	2006-12-15
NZ531340A (en)	2005-08-26
PL368502A1 (en)	2005-04-04
RU2298011C2 (ru)	2007-04-27
ZA200401455B (en)	2004-11-19
TWI228508B (en)	2005-03-01
DE60216128T2 (de)	2007-09-27
EP1427733B1 (en)	2006-11-15
CA2456901C (en)	2011-01-04
HUP0401444A2 (hu)	2004-11-29
KR20040029134A (ko)	2004-04-03
ES2275005T3 (es)	2007-06-01
PT1427733E (pt)	2007-02-28
HUP0401444A3 (en)	2008-05-28
NO20040927L (no)	2004-03-03
PE20030439A1 (es)	2003-05-17
US20040180873A1 (en)	2004-09-16
CN1551884A (zh)	2004-12-01
US7317006B2 (en)	2008-01-08
KR100900018B1 (ko)	2009-06-01
CN1246324C (zh)	2006-03-22
EP1427733A1 (en)	2004-06-16
RU2004110042A (ru)	2005-08-20
AR036407A1 (es)	2004-09-08

Publication	Publication Date	Title
CY1106012T1 (el)	2011-04-06	Thieno[2,3-d]pyrimidines με συνδυασμενη αγωνιστικη δραστηριοτητα της ωχρινοτροπου (lh) και της ωοθυλακιοτροπου (fsh) ορμονης
ATE407679T1 (de)	2008-09-15	Pyrimidin-2,4-dion-derivate als gonadotropin freisetzende hormon-rezeptor-antagonisten
PL373414A1 (en)	2005-08-22	8-methoxy-(1,2,4)triazolo(1,5-a)pyridine derivatives and their use as adenosine receptor ligands
UA83101C2 (en)	2008-06-10	2,6-bisheteroaryl-4-aminopyrimidines as adenosine receptor antagonists
ATE428427T1 (de)	2009-05-15	Pyrimidin-2,4-dion-derivate als gonadotropin freisetzende hormon-rezeptor-antagonisten
MXPA04003795A (es)	2004-07-30	Compuestos de pirimidina y composiciones farmaceuticas que contienen los compuestos.
TR200102839T2 (tr)	2002-04-22	LH agonistleri olarak faydalı bisiklik heteroaromatik bileşikler.
IL155702A0 (en)	2003-11-23	Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5-ht2 receptor
GEP20074099B (en)	2007-05-10	3-β-D-RIBOFURANO-SYLTHIAZOLO[4,5-d]PYRIDIMINE NUCLEOSIDES AND USES THEREOF
MXPA06000716A (es)	2006-03-30	Derivados de quinolina y quinazolina que tienen afinidad hacia receptores del tipo 5ht1.
WO2003011293A3 (en)	2003-04-17	Pyridinone and pyridazinone derivatives as gonadotropin-releasing hormone receptor antagonists
WO2006100635A3 (en)	2007-01-18	Novel thiophene derivatives as sphingosine-1-phosphate-1 receptor agonists
DE602004018637D1 (de)	2009-02-05	A2a-adenosinrezeptorantagonisten
GEP20105095B (en)	2010-10-25	Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents
WO2003068776A1 (en)	2003-08-21	[1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE DERIVATIVES
MXPA03003923A (es)	2004-05-05	Compuestos de n-([1,2,4]triazoloazinil)tiofensulfonamida como herbicidas.
CA2412594A1 (en)	2002-01-03	Pyrazino[1',2':1,6]pyrido[3-4-5] indole derivatives
TW200626145A (en)	2006-08-01	Heterocyclic compounds and thrombopoietin receptor activators
TR199902019T2 (xx)	1999-12-21	�kame edilmi� tiazolidion' un haz�rlanmas� i�in proses.
MXPA04003278A (es)	2004-07-23	Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina.
IS2419B (is)	2008-10-15	Glýsín-setin þíeno[2,3-d]pýrimidín með sameinaða LH og FSH gerandefnisvirkni
DK1140810T3 (da)	2004-07-19	Benzensulfonamidderivater samt deres anvendelse
DK1087973T3 (da)	2003-02-24	Imidazotriazolopyrimidiner som lægemiddel med adenosinantagonist effekt
ATE318268T1 (de)	2006-03-15	Pyrazolyl-substituierte triazolochinoxaline
WO2003020723A1 (en)	2003-03-13	[1,2,4]TRIAZOLO[1,5-a]PYRIMIDINE DERIVATIVE