HRP20100412T1 - Identifikacija površinskih antigena radi dijagnoze i liječenja tumora - Google Patents

Identifikacija površinskih antigena radi dijagnoze i liječenja tumora Download PDF

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Publication number
HRP20100412T1
HRP20100412T1 HR20100412T HRP20100412T HRP20100412T1 HR P20100412 T1 HRP20100412 T1 HR P20100412T1 HR 20100412 T HR20100412 T HR 20100412T HR P20100412 T HRP20100412 T HR P20100412T HR P20100412 T1 HRP20100412 T1 HR P20100412T1
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Croatia
Prior art keywords
tumor
antigen
nucleic acid
fragment
tumor antigen
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HR20100412T
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English (en)
Croatian (hr)
Inventor
Treci Zlem
Sahin Ugur
Schneider Sandra
Helftenbein Gerd
Schl�ter Volker
Usener Dirk
Thiel Philippe
Koslowski Michael
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Ganymed Pharmaceuticals Ag
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Application filed by Ganymed Pharmaceuticals Ag filed Critical Ganymed Pharmaceuticals Ag
Publication of HRP20100412T1 publication Critical patent/HRP20100412T1/hr

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HR20100412T 2004-05-11 2005-05-11 Identifikacija površinskih antigena radi dijagnoze i liječenja tumora HRP20100412T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004023187A DE102004023187A1 (de) 2004-05-11 2004-05-11 Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
PCT/EP2005/005104 WO2005110338A2 (fr) 2004-05-11 2005-05-11 Identification d'antigenes de surface pour le diagnostic et la therapie de tumeurs

Publications (1)

Publication Number Publication Date
HRP20100412T1 true HRP20100412T1 (hr) 2010-09-30

Family

ID=35064875

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100412T HRP20100412T1 (hr) 2004-05-11 2005-05-11 Identifikacija površinskih antigena radi dijagnoze i liječenja tumora

Country Status (14)

Country Link
US (5) US7785801B2 (fr)
EP (18) EP2258867A3 (fr)
JP (6) JP2007537197A (fr)
AT (1) ATE468409T1 (fr)
AU (1) AU2005244425B2 (fr)
CA (2) CA2820168C (fr)
DE (2) DE102004023187A1 (fr)
DK (1) DK1759013T3 (fr)
ES (1) ES2346067T3 (fr)
HR (1) HRP20100412T1 (fr)
PL (1) PL1759013T3 (fr)
PT (1) PT1759013E (fr)
SI (1) SI1759013T1 (fr)
WO (1) WO2005110338A2 (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10347710B4 (de) 2003-10-14 2006-03-30 Johannes-Gutenberg-Universität Mainz Rekombinante Impfstoffe und deren Verwendung
DE102004023187A1 (de) * 2004-05-11 2005-12-01 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
DE102005046490A1 (de) 2005-09-28 2007-03-29 Johannes-Gutenberg-Universität Mainz Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
US8535677B2 (en) 2006-06-06 2013-09-17 Oxford Biotherapeutics, Ltd. Antibody drug conjugate treatment of colorectal cancer
GB0611116D0 (en) * 2006-06-06 2006-07-19 Oxford Genome Sciences Uk Ltd Proteins
EP2050466B1 (fr) * 2006-08-14 2015-10-28 Chugai Seiyaku Kabushiki Kaisha Diagnostic et traitement du cancer à l'aide de l'anticorps anti-desmogleine-3
DE102007034993A1 (de) * 2007-07-26 2009-01-29 Hanna Diehl Lösliches Cadherin 17 für die Diagnose und Risikostratifizierung von Darmtumor oder Darmkrebs
CA2729133C (fr) * 2008-06-25 2014-12-30 Institut Pasteur Korea Identification visuelle sur l'ensemble du genome de co-facteurs humains de l'infection par le vih-1
WO2010041349A1 (fr) * 2008-10-10 2010-04-15 独立行政法人 放射線医学総合研究所 Marqueur pour estimer le pronostic d'un adénocarcinome du col de l'utérus ou pour estimer le pronostic d'un cancer du col de l'utérus
DK2421898T3 (en) 2009-04-20 2016-05-30 Oxford Biotherapeutics Ltd Cadherin-17 SPECIFIC ANTIBODIES
SG185027A1 (en) * 2010-05-03 2012-11-29 Genentech Inc Compositions and methods for the diagnosis and treatment of tumor
US20130259878A1 (en) * 2010-10-20 2013-10-03 Oxford Biotherapeutics Ltd Antibodies
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
PL3892295T3 (pl) 2011-05-24 2023-07-24 BioNTech SE Zindywidualizowane szczepionki przeciwnowotworowe
CN102311242B (zh) * 2011-05-27 2014-10-01 刘长福 一种造纸废液生产的水溶性高分子助磨剂及制造方法
KR101314828B1 (ko) * 2011-09-26 2013-10-04 한국원자력연구원 비소세포성 폐암에서 tm4sf4의 발현 또는 활성의 조절을 통한 방사선 저항성 및 암세포의 성장, 전이, 및 침윤능력을 저하시키는 방법
WO2013143555A1 (fr) 2012-03-26 2013-10-03 Biontech Ag Formulation d'arn pour immunothérapie
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
EP3417874B1 (fr) 2012-11-28 2024-09-11 BioNTech SE Vaccins individualisés pour le cancer
WO2014180490A1 (fr) 2013-05-10 2014-11-13 Biontech Ag Prédiction de l'immunogénicité d'épitopes de lymphocytes t
AU2014343379B2 (en) 2013-11-04 2019-02-14 Uti Limited Partnership Methods and compositions for sustained immunotherapy
CN113791220A (zh) 2014-09-10 2021-12-14 豪夫迈·罗氏有限公司 免疫原性突变体肽筛选平台
WO2016045732A1 (fr) 2014-09-25 2016-03-31 Biontech Rna Pharmaceuticals Gmbh Formulations stables de lipides et de liposomes
WO2016128060A1 (fr) 2015-02-12 2016-08-18 Biontech Ag Prédiction des épitopes de lymphocytes t utiles pour la vaccination
JP6492914B2 (ja) 2015-04-15 2019-04-03 株式会社デンソー 光走査装置
ES2939013T3 (es) * 2015-04-20 2023-04-18 Consejo Superior Investigacion Agentes que se unen específicamente al motivo RGD de la cadherina 17 humana, la cadherina 5 humana, la cadherina 6 humana y la cadherina 20 humana
EP3291832B1 (fr) 2015-05-06 2025-09-03 UTI Limited Partnership Compositions de nanoparticules pour thérapie prolongée
US11254744B2 (en) 2015-08-07 2022-02-22 Imaginab, Inc. Antigen binding constructs to target molecules
WO2017059902A1 (fr) 2015-10-07 2017-04-13 Biontech Rna Pharmaceuticals Gmbh Séquences utr 3' permettant la stabilisation d'arn
SI3383920T1 (sl) 2015-11-30 2024-06-28 The Regents Of The University Of California Dostava tumorsko specifičnega koristnega tovora in imunska aktivacija z uporabo humanega protitelesa, ki cilja visoko specifičen površinski antigen tumorskih celic
ES2970865T3 (es) 2015-12-16 2024-05-31 Gritstone Bio Inc Identificación, fabricación y uso de neoantígenos
US11241455B2 (en) 2016-01-15 2022-02-08 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Methods of treating disease by metabolic control of T-cell differentiation
US11266745B2 (en) 2017-02-08 2022-03-08 Imaginab, Inc. Extension sequences for diabodies
CN106919801B (zh) * 2017-03-08 2023-07-18 杭州大伽信息科技有限公司 一种免疫组织化学染色辅助分析系统及使用方法
WO2018224166A1 (fr) 2017-06-09 2018-12-13 Biontech Rna Pharmaceuticals Gmbh Procédés de prédiction de l'utilité de modifications d'acides aminés spécifiques d'une maladie pour l'immunothérapie
EP4576103A3 (fr) 2017-10-10 2025-08-27 Gritstone bio, Inc. Identification de néoantigènes à l'aide de points chauds
CN111630602A (zh) 2017-11-22 2020-09-04 磨石肿瘤生物技术公司 减少新抗原的接合表位呈递
CA3083748A1 (fr) 2017-11-29 2019-06-06 Uti Limited Partnership Methodes de traitement d'une maladie auto-immune
WO2019183683A1 (fr) * 2018-03-29 2019-10-03 The University Of Newcastle Procédés de diagnostic et de pronostic pour des cancers induits par les oestrogènes
WO2020263796A1 (fr) * 2019-06-23 2020-12-30 Guangdong Tcrcure Biopharma Technology Co., Ltd. Thérapie par cellules car-t anti-alpp
US12421309B2 (en) 2019-12-06 2025-09-23 Korea Atomic Energy Research Institute Anti-TM4SF4 antibody and uses thereof
CN117597363A (zh) * 2021-06-18 2024-02-23 韩国原子力研究院 抗-tm4sf4人源化抗体及其用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732847A (en) * 1981-06-09 1988-03-22 University Of Hawaii Monoclonal antibodies for DNA-RNA hybrid complexes and their uses
US5081227A (en) * 1988-03-04 1992-01-14 La Jolla Cancer Research Foundation Germ cell alkaline phosphatase
GB9019812D0 (en) 1990-09-11 1990-10-24 Scotgen Ltd Novel antibodies for treatment and prevention of infection in animals and man
AU3178393A (en) 1991-11-27 1993-06-28 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Nucleotide and amino acid sequence of pemphigus vulgaris antigen and methods of use
US5677139A (en) 1995-04-21 1997-10-14 President And Fellows Of Harvard College In vitro differentiation of CD34+ progenitor cells into T lymphocytes
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
CA2243235C (fr) 1996-01-17 2010-08-10 Imperial College Innovations Limited Immunotherapie utilisant des lymphocytes t cytotoxiques (ctl)
JP2003530816A (ja) 1998-09-28 2003-10-21 カイロン コーポレイション ヒト遺伝子および遺伝子発現産物
EP1252300B1 (fr) * 2000-02-03 2011-01-19 Dendreon Corporation Molecules d'acides nucleiques codant pour des proteases a serine transmembranaires, proteines codees et procedes associes
KR100374423B1 (ko) * 2000-04-25 2003-03-28 주식회사 아이씨엔지 다수의 mage 아형 또는 gage 아형을 인식하는암진단용 프라이머
CA2411601A1 (fr) * 2000-06-05 2001-12-13 Avalon Pharmaceuticals Determination de gene du cancer et recherche therapeutique utilisant des ensembles de genes signature
ES2284678T3 (es) * 2000-08-15 2007-11-16 Immunex Corporation Polipeptidos de claudinas.
US6697557B2 (en) * 2000-10-04 2004-02-24 University Of South Florida Two-dimensional optical filter and associated methods
DE10057894A1 (de) * 2000-11-22 2002-06-06 Adnagen Gmbh Diagnose-Kit, DNS-Chip sowie Verfahren zur Diagnostik oder Behandlungskontrolle bei Hodenkrebs
AU2002309583A1 (en) 2001-04-18 2002-11-05 Protein Desing Labs, Inc. Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
US20050037445A1 (en) * 2001-06-25 2005-02-17 Poulsen Hans Skovgaard Oncology drug innovation
US20040076955A1 (en) * 2001-07-03 2004-04-22 Eos Biotechnology, Inc. Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
WO2003018621A2 (fr) * 2001-08-23 2003-03-06 Oxford Biomedica (Uk) Limited Genes
JP2003088388A (ja) * 2001-09-14 2003-03-25 Herikkusu Kenkyusho:Kk 新規な全長cDNA
EP1293569A3 (fr) * 2001-09-14 2004-03-31 Research Association for Biotechnology Clones d'ADNc complets
DE10211088A1 (de) 2002-03-13 2003-09-25 Ugur Sahin Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DE10254601A1 (de) * 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
CA2522184A1 (fr) * 2003-04-17 2004-11-04 The Trustees Of Columbia University In The City Of New York Desmogleine 4, nouveau gene de la croissance des cheveux
WO2004106511A1 (fr) * 2003-05-30 2004-12-09 Nippon Shinyaku Co., Ltd. Arn oligobicatenaire inhibant l'expression de bcl-2 et composition medicinale contenant cet arn
DE102004023187A1 (de) 2004-05-11 2005-12-01 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie

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EP2290104A3 (fr) 2011-06-22
JP2015083576A (ja) 2015-04-30
EP2348135A3 (fr) 2011-10-19
EP2270209A3 (fr) 2011-04-20
EP2267158A3 (fr) 2011-04-06
EP2290103A3 (fr) 2011-06-22
EP2290103A2 (fr) 2011-03-02
EP1759013B1 (fr) 2010-05-19
JP2012077085A (ja) 2012-04-19
EP2258867A2 (fr) 2010-12-08
EP2280082A3 (fr) 2011-05-18
EP2239340A2 (fr) 2010-10-13
JP5732369B2 (ja) 2015-06-10
CA2563671A1 (fr) 2005-11-24
EP2290104A2 (fr) 2011-03-02
EP2267156A3 (fr) 2011-04-20
PT1759013E (pt) 2010-08-17
AU2005244425B2 (en) 2011-10-13
EP2275570A2 (fr) 2011-01-19
US10724103B2 (en) 2020-07-28
US9255131B2 (en) 2016-02-09
EP2275571A2 (fr) 2011-01-19
JP2013032381A (ja) 2013-02-14
EP2280082A2 (fr) 2011-02-02
JP2016179986A (ja) 2016-10-13
US7785801B2 (en) 2010-08-31
EP1759013A2 (fr) 2007-03-07
EP2267158A2 (fr) 2010-12-29
JP5796003B2 (ja) 2015-10-21
EP2287337A3 (fr) 2011-04-20
EP2258869A3 (fr) 2011-04-06
EP2267156A2 (fr) 2010-12-29
AU2005244425A1 (en) 2005-11-24
EP2258869A2 (fr) 2010-12-08
EP2258867A3 (fr) 2011-04-06
EP2275571A3 (fr) 2012-11-21
DE502005009602D1 (de) 2010-07-01
EP2270209A2 (fr) 2011-01-05
JP2018104464A (ja) 2018-07-05
ES2346067T3 (es) 2010-10-08
EP2287337A2 (fr) 2011-02-23
EP2275570A3 (fr) 2011-06-22
US20140120085A1 (en) 2014-05-01
US20110014628A1 (en) 2011-01-20
DK1759013T3 (da) 2010-08-30
DE102004023187A1 (de) 2005-12-01
EP2267157A3 (fr) 2011-05-11
CA2820168A1 (fr) 2005-11-24
JP2007537197A (ja) 2007-12-20
EP2258868A3 (fr) 2011-04-06
SI1759013T1 (sl) 2010-09-30
JP6434444B2 (ja) 2018-12-05
PL1759013T3 (pl) 2010-10-29
CA2820168C (fr) 2019-08-20
US9533043B2 (en) 2017-01-03
ATE468409T1 (de) 2010-06-15
WO2005110338A3 (fr) 2006-06-29
EP2275572A3 (fr) 2011-05-11
EP2267157A2 (fr) 2010-12-29
EP2275572A2 (fr) 2011-01-19
WO2005110338A2 (fr) 2005-11-24
US20160193335A1 (en) 2016-07-07
EP2239340A3 (fr) 2010-11-17
US20180169236A1 (en) 2018-06-21
EP2348135A2 (fr) 2011-07-27
EP2280082B1 (fr) 2016-08-10
US20080193454A1 (en) 2008-08-14
EP2258868A2 (fr) 2010-12-08
EP3382036A1 (fr) 2018-10-03

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