HRP20100526T1 - Piridooksazepinski modulatori progesteronskog receptora - Google Patents

Piridooksazepinski modulatori progesteronskog receptora Download PDF

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Publication number
HRP20100526T1
HRP20100526T1 HR20100526T HRP20100526T HRP20100526T1 HR P20100526 T1 HRP20100526 T1 HR P20100526T1 HR 20100526 T HR20100526 T HR 20100526T HR P20100526 T HRP20100526 T HR P20100526T HR P20100526 T1 HRP20100526 T1 HR P20100526T1
Authority
HR
Croatia
Prior art keywords
compound according
compound
intended
formula
alkyl
Prior art date
Application number
HR20100526T
Other languages
English (en)
Croatian (hr)
Inventor
Bernardus Maria Rewinkel Johannes
Johanna Bernita Folmer Brigitte
Lourdes Ollero-Ollero Maria
Ibrahim Hemen
Original Assignee
N.V. Organon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N.V. Organon filed Critical N.V. Organon
Publication of HRP20100526T1 publication Critical patent/HRP20100526T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20100526T 2006-09-27 2007-09-26 Piridooksazepinski modulatori progesteronskog receptora HRP20100526T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06121372 2006-09-27
PCT/EP2007/060225 WO2008037746A1 (en) 2006-09-27 2007-09-26 Pyridooxazepine progesteron receptor modulators

Publications (1)

Publication Number Publication Date
HRP20100526T1 true HRP20100526T1 (hr) 2010-11-30

Family

ID=37813577

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100526T HRP20100526T1 (hr) 2006-09-27 2007-09-26 Piridooksazepinski modulatori progesteronskog receptora

Country Status (27)

Country Link
EP (1) EP2066677B1 (pl)
JP (1) JP2010504943A (pl)
KR (1) KR20090064454A (pl)
CN (1) CN101522689B (pl)
AR (1) AR063018A1 (pl)
AT (1) ATE478078T1 (pl)
AU (1) AU2007302007B2 (pl)
BR (1) BRPI0716830A2 (pl)
CA (1) CA2664120A1 (pl)
CL (1) CL2007002788A1 (pl)
CO (1) CO6160325A2 (pl)
CY (1) CY1110846T1 (pl)
DE (1) DE602007008589D1 (pl)
DK (1) DK2066677T3 (pl)
ES (1) ES2349325T3 (pl)
HR (1) HRP20100526T1 (pl)
IL (1) IL197365A0 (pl)
MX (1) MX2009002804A (pl)
NO (1) NO20091016L (pl)
NZ (1) NZ575276A (pl)
PE (1) PE20071451A1 (pl)
PL (1) PL2066677T3 (pl)
PT (1) PT2066677E (pl)
RU (1) RU2009115643A (pl)
SI (1) SI2066677T1 (pl)
TW (1) TW200820975A (pl)
WO (1) WO2008037746A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
CN101200429B (zh) * 2006-12-13 2012-08-22 上海睿智化学研究有限公司 2-硝基-4,5-二卤代苯酚类和2-氨基-4,5-二卤代苯酚类及其盐及其合成方法
US8063037B2 (en) 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004508373A (ja) * 2000-09-07 2004-03-18 バイエル・フアーマシユーチカルズ・コーポレーシヨン 環式および非環式アミジンおよびプロゲステロン受容体結合剤として使用するためのそれらを含有する医薬組成物
TWI297685B (en) * 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators

Also Published As

Publication number Publication date
CA2664120A1 (en) 2008-04-03
PT2066677E (pt) 2010-11-10
JP2010504943A (ja) 2010-02-18
PE20071451A1 (es) 2008-10-30
CL2007002788A1 (es) 2008-04-18
AR063018A1 (es) 2008-12-23
AU2007302007B2 (en) 2012-02-02
CN101522689B (zh) 2012-01-11
EP2066677B1 (en) 2010-08-18
HK1126767A1 (en) 2009-09-11
SI2066677T1 (sl) 2010-12-31
DK2066677T3 (da) 2010-11-08
AU2007302007A1 (en) 2008-04-03
RU2009115643A (ru) 2010-11-10
TW200820975A (en) 2008-05-16
CY1110846T1 (el) 2015-06-10
EP2066677A1 (en) 2009-06-10
CO6160325A2 (es) 2010-05-20
PL2066677T3 (pl) 2011-02-28
KR20090064454A (ko) 2009-06-18
WO2008037746A1 (en) 2008-04-03
CN101522689A (zh) 2009-09-02
ATE478078T1 (de) 2010-09-15
NZ575276A (en) 2011-07-29
NO20091016L (no) 2009-03-30
IL197365A0 (en) 2009-12-24
MX2009002804A (es) 2009-03-31
BRPI0716830A2 (pt) 2013-11-05
DE602007008589D1 (de) 2010-09-30
ES2349325T3 (es) 2010-12-30

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