HRP20100565T1 - Postupak priprave kontrastnih sredstava - Google Patents

Postupak priprave kontrastnih sredstava Download PDF

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Publication number
HRP20100565T1
HRP20100565T1 HR20100565T HRP20100565T HRP20100565T1 HR P20100565 T1 HRP20100565 T1 HR P20100565T1 HR 20100565 T HR20100565 T HR 20100565T HR P20100565 T HRP20100565 T HR P20100565T HR P20100565 T1 HRP20100565 T1 HR P20100565T1
Authority
HR
Croatia
Prior art keywords
formula
compound
iii
aliquots
base
Prior art date
Application number
HR20100565T
Other languages
English (en)
Croatian (hr)
Inventor
Ceragioli Silvia
Luca Ciarciello Giovanni
Castiglia Luciano
Original Assignee
Bracco Imaging S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging S.P.A. filed Critical Bracco Imaging S.P.A.
Publication of HRP20100565T1 publication Critical patent/HRP20100565T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
HR20100565T 2005-09-13 2006-08-24 Postupak priprave kontrastnih sredstava HRP20100565T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05019852A EP1762563A1 (en) 2005-09-13 2005-09-13 Process for the preparation of contrast agents
PCT/EP2006/065634 WO2007031390A1 (en) 2005-09-13 2006-08-24 Process for the preparation of contrast agents

Publications (1)

Publication Number Publication Date
HRP20100565T1 true HRP20100565T1 (hr) 2010-11-30

Family

ID=35501122

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100565T HRP20100565T1 (hr) 2005-09-13 2006-08-24 Postupak priprave kontrastnih sredstava

Country Status (17)

Country Link
US (2) US7592482B2 (pl)
EP (2) EP1762563A1 (pl)
JP (1) JP5108769B2 (pl)
KR (1) KR101358058B1 (pl)
CN (1) CN101263108B (pl)
AT (1) ATE478040T1 (pl)
AU (1) AU2006290947B2 (pl)
CA (1) CA2621339C (pl)
DE (1) DE602006016320D1 (pl)
DK (1) DK1948590T3 (pl)
ES (1) ES2351166T3 (pl)
HR (1) HRP20100565T1 (pl)
IL (1) IL189643A (pl)
NO (1) NO340308B1 (pl)
PL (1) PL1948590T3 (pl)
SI (1) SI1948590T1 (pl)
WO (1) WO2007031390A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501988B2 (en) * 2008-04-17 2013-08-06 Ecolab Usa Inc. Synthesis and applications of amino carboxylates
EP2327395A1 (en) 2009-11-23 2011-06-01 Bracco Imaging S.p.A Process for the preparation of gadobenate dimeglumine complex in a solid form
EP2338874A1 (en) 2009-12-16 2011-06-29 Bracco Imaging S.p.A Process for the preparation of chelated compounds
IT1403988B1 (it) * 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
RU2621896C2 (ru) * 2011-11-25 2017-06-08 Байофор Индиа Фармасьютикалз Пвт. Лтд. Способ очистки полиаминокарбоксилатов
CN102603550B (zh) * 2012-02-16 2014-11-26 佛山普正医药科技有限公司 一种中间体bopta的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3855239T2 (de) * 1987-07-16 1996-10-31 Nycomed Imaging As Aminocarbonsäure und Derivate
EP0703790B1 (en) * 1993-06-02 2000-08-16 BRACCO S.p.A. Iodinated paramagnetic chelates, and their use as contrast agents
IT1291624B1 (it) * 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
ITMI981583A1 (it) * 1998-07-10 2000-01-10 Bracco Spa Processo per la preparazione dell'acido 4 -carbossi-5,8,11-tris (carbossimetil)-1-fenil-2-oxa-5,8,11-triazatridecan-13-oico
JP5004438B2 (ja) * 2005-06-09 2012-08-22 行政院原子能委員会核能研究所 Ｄｔｐａ誘導体の製造方法

Also Published As

Publication number Publication date
EP1948590B1 (en) 2010-08-18
US7592482B2 (en) 2009-09-22
JP5108769B2 (ja) 2012-12-26
NO340308B1 (no) 2017-03-27
CN101263108B (zh) 2011-12-21
AU2006290947A1 (en) 2007-03-22
NO20081655L (no) 2008-04-09
EP1948590A1 (en) 2008-07-30
DK1948590T3 (da) 2010-11-29
ES2351166T3 (es) 2011-02-01
PL1948590T3 (pl) 2011-03-31
CA2621339A1 (en) 2007-03-22
US20090118537A1 (en) 2009-05-07
KR101358058B1 (ko) 2014-02-06
ATE478040T1 (de) 2010-09-15
AU2006290947B2 (en) 2012-01-19
CA2621339C (en) 2011-04-26
IL189643A (en) 2012-03-29
US20090306424A1 (en) 2009-12-10
DE602006016320D1 (pl) 2010-09-30
JP2009507882A (ja) 2009-02-26
SI1948590T1 (sl) 2010-12-31
CN101263108A (zh) 2008-09-10
EP1762563A1 (en) 2007-03-14
KR20080045724A (ko) 2008-05-23
WO2007031390A1 (en) 2007-03-22

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