HRP20110048T1 - Spojevi piperidina i njihova upotreba - Google Patents

Spojevi piperidina i njihova upotreba Download PDF

Info

Publication number
HRP20110048T1
HRP20110048T1 HR20110048T HRP20110048T HRP20110048T1 HR P20110048 T1 HRP20110048 T1 HR P20110048T1 HR 20110048 T HR20110048 T HR 20110048T HR P20110048 T HRP20110048 T HR P20110048T HR P20110048 T1 HRP20110048 T1 HR P20110048T1
Authority
HR
Croatia
Prior art keywords
methyl
thiazole
amino
dichloro
carbonyl
Prior art date
Application number
HR20110048T
Other languages
English (en)
Croatian (hr)
Inventor
Basarab Gregory
Hill Pamela
Zhou Fei
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HRP20110048T1 publication Critical patent/HRP20110048T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HR20110048T 2007-06-12 2008-06-11 Spojevi piperidina i njihova upotreba HRP20110048T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94344007P 2007-06-12 2007-06-12
PCT/GB2008/050431 WO2008152418A1 (en) 2007-06-12 2008-06-11 Piperidine compounds and uses thereof

Publications (1)

Publication Number Publication Date
HRP20110048T1 true HRP20110048T1 (hr) 2011-03-31

Family

ID=39673349

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20110048T HRP20110048T1 (hr) 2007-06-12 2008-06-11 Spojevi piperidina i njihova upotreba

Country Status (29)

Country Link
US (1) US20080312255A1 (da)
EP (1) EP2158199B1 (da)
JP (1) JP2010529184A (da)
KR (1) KR20100038095A (da)
CN (1) CN102648199A (da)
AR (1) AR066977A1 (da)
AT (1) ATE488514T1 (da)
AU (1) AU2008263580A1 (da)
BR (1) BRPI0812473A2 (da)
CA (1) CA2689076A1 (da)
CL (1) CL2008001740A1 (da)
CO (1) CO6311102A2 (da)
CY (1) CY1111442T1 (da)
DE (1) DE602008003575D1 (da)
DK (1) DK2158199T3 (da)
ES (1) ES2354647T3 (da)
HR (1) HRP20110048T1 (da)
IL (1) IL202367A0 (da)
MX (1) MX2009013501A (da)
NZ (1) NZ582516A (da)
PE (1) PE20090555A1 (da)
PL (1) PL2158199T3 (da)
PT (1) PT2158199E (da)
RU (1) RU2010100352A (da)
SA (1) SA08290357B1 (da)
SI (1) SI2158199T1 (da)
TW (1) TW200906412A (da)
UY (1) UY31141A1 (da)
WO (1) WO2008152418A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4058106B2 (ja) * 2005-02-18 2008-03-05 アストラゼネカ アクチボラグ 抗菌性のピペリジン誘導体
TW201026694A (en) * 2008-12-12 2010-07-16 Astrazeneca Ab Compound 468
TW201026695A (en) * 2008-12-12 2010-07-16 Astrazeneca Ab Piperidine compounds and uses thereof-596
TW201111380A (en) 2009-08-26 2011-04-01 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
US9364405B2 (en) 2013-03-13 2016-06-14 Avon Products, Inc. Tyrosinase inhibitors
US20150174034A1 (en) 2013-03-13 2015-06-25 Avon Products, Inc. Tyrosinase inhibitors
EP3356361B1 (en) 2015-09-30 2020-07-08 Daiichi Sankyo Company, Limited Hydroxyalkyl thiadiazole derivatives
CA3056571C (en) 2017-03-14 2021-11-23 Daiichi Sankyo Company, Limited N-phosphonoxymethyl prodrugs of hydroxyalkyl thiadiazole derivatives
CA3057431A1 (en) 2017-03-24 2018-09-27 Taisho Pharmaceutical Co., Ltd. 2(1h)-quinolinone derivative
EP3847172A1 (en) 2018-09-03 2021-07-14 Univerza v Ljubljani New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
CN110172435B (zh) * 2019-06-06 2020-12-29 江南大学 一种催化合成2,5-二甲基吡嗪的重组菌
WO2022129327A1 (en) 2020-12-17 2022-06-23 Univerza V Ljubljani New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity
CN115466246B (zh) * 2021-06-11 2024-02-06 中国医学科学院药物研究所 吡咯酰哌啶胺类化合物及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963480A (en) * 1973-04-11 1976-06-15 Sterling Drug Inc. Herbicidal pyrrole-2-carboxamides
US4046775A (en) * 1973-04-11 1977-09-06 Sterling Drug Inc. 4,5-Dihalopyrrole-2-carboxamides
US4791112A (en) * 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds
US4912109A (en) * 1987-02-02 1990-03-27 Boc, Inc. N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compositions and methods employing such compounds
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
JP2003520233A (ja) * 2000-01-18 2003-07-02 バーテックス ファーマシューティカルズ インコーポレイテッド ジャイレースインヒビターおよびそれらの使用
PL374191A1 (en) * 2002-06-13 2005-10-03 Vertex Pharmaceuticals Incorporated 2-ureido-6-heteroaryl-3h-benzoimidazole-4-carboxylic acid derivatives and related compounds as gyrase and/or topoisomerase iv inhibitors for the treatment of bacterial infections
GB0321509D0 (en) * 2003-09-13 2003-10-15 Astrazeneca Ab Chemical compounds
TW200526626A (en) * 2003-09-13 2005-08-16 Astrazeneca Ab Chemical compounds
US20050197336A1 (en) * 2004-03-08 2005-09-08 Miikana Therapeutics Corporation Inhibitors of histone deacetylase
US7345043B2 (en) * 2004-04-01 2008-03-18 Miikana Therapeutics Inhibitors of histone deacetylase
JP4058106B2 (ja) * 2005-02-18 2008-03-05 アストラゼネカ アクチボラグ 抗菌性のピペリジン誘導体
TW200819437A (en) * 2006-08-17 2008-05-01 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
DE602008003575D1 (de) 2010-12-30
SA08290357B1 (ar) 2011-06-22
EP2158199A1 (en) 2010-03-03
ES2354647T3 (es) 2011-03-16
HK1140198A1 (en) 2010-10-08
JP2010529184A (ja) 2010-08-26
IL202367A0 (en) 2010-06-30
RU2010100352A (ru) 2011-07-20
CO6311102A2 (es) 2011-08-22
CN102648199A (zh) 2012-08-22
AR066977A1 (es) 2009-09-23
CA2689076A1 (en) 2008-12-18
DK2158199T3 (da) 2011-02-07
PT2158199E (pt) 2011-01-19
NZ582516A (en) 2012-03-30
AU2008263580A1 (en) 2008-12-18
PE20090555A1 (es) 2009-06-04
ATE488514T1 (de) 2010-12-15
CY1111442T1 (el) 2015-08-05
TW200906412A (en) 2009-02-16
US20080312255A1 (en) 2008-12-18
MX2009013501A (es) 2010-01-18
SI2158199T1 (sl) 2011-02-28
EP2158199B1 (en) 2010-11-17
KR20100038095A (ko) 2010-04-12
UY31141A1 (es) 2009-01-30
CL2008001740A1 (es) 2009-07-17
WO2008152418A1 (en) 2008-12-18
BRPI0812473A2 (pt) 2014-12-02
PL2158199T3 (pl) 2011-04-29

Similar Documents

Publication Publication Date Title
HRP20110048T1 (hr) Spojevi piperidina i njihova upotreba
RU2009125441A (ru) Химические соединения
RU2401265C2 (ru) Соединения и композиции в качестве ингибиторов протеинкиназы
RU2013143028A (ru) Тиазолилфенилбензолсульфонамидопроизводные в качестве ингибиторов киназ
ES2322709T3 (es) Derivados de benzamida y su uso como agentes activadores de la glucocinasa.
RU2018143324A (ru) Применение 1H-пиразоло[4,3-b]пиридинов в качестве ингибиторов PDE1
HRP20120240T1 (hr) Piridil piperidin antagonisti receptora za oreksin
HRP20180382T1 (hr) Inhibitori protein kinaze
HRP20230595T1 (hr) Inhibitori lizina specifične demetilaze-1
KR20060105872A (ko) 신규한 2-헤테로아릴 치환된 벤즈이미다졸 유도체
JP2013523819A5 (da)
RU2016133684A (ru) Бициклические азот-содержащие соединения как агонисты М1 мускариновых рецепторов
ME00681B (me) Jedinjenje indola
JP2010533158A5 (da)
HRP20160421T1 (hr) Derivat azola
CA2648157A1 (en) 1-alkyl-5-aryl-3-arylamino-1h-1,2,4-triazoles as positive allosteric modulators of the alpha 7 receptor
HRP20140588T1 (hr) Spojevi kondenziranog prstena i njihova uporaba
IL187690A (en) Derivatives 1, 2, 4 - Triazolo - 1, 6 - Naphthiridines as inhibitors of AKT activity for use in the preparation of drugs for the treatment of cancer
RU2017125520A (ru) Соединения, ингибирующие parg
JP2007501189A5 (da)
HRP20161396T1 (hr) Derivati 2-(fenil ili pirid-3-il)aminopirimidina kao modulatori lrrk2-kinaze za liječenje parkinsonove bolesti
CA2642922A1 (en) Melanocortin type 4 receptor agonist piperidinoylpyrrolidines
RU2012133475A (ru) Ингибиторы кинуренин-3-монооксигеназы, фармацевтические композиции и способы их применения
JP2009525978A5 (da)
JP2015509510A5 (da)