HRP20110883T1 - Postupak za pripremanje raspršivanjem osušenih formulacija tmc125 - Google Patents

Postupak za pripremanje raspršivanjem osušenih formulacija tmc125 Download PDF

Info

Publication number
HRP20110883T1
HRP20110883T1 HR20110883T HRP20110883T HRP20110883T1 HR P20110883 T1 HRP20110883 T1 HR P20110883T1 HR 20110883 T HR20110883 T HR 20110883T HR P20110883 T HRP20110883 T HR P20110883T HR P20110883 T1 HRP20110883 T1 HR P20110883T1
Authority
HR
Croatia
Prior art keywords
tmc125
polymer
microcrystalline cellulose
weight ratio
charge
Prior art date
Application number
HR20110883T
Other languages
English (en)
Croatian (hr)
Inventor
Rene Irene Kiekens Filip
Firmin Marceline Voorspoels Jody
Elvire Colette Baert Lieven
Original Assignee
Tibotec Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37179187&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20110883(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharmaceuticals filed Critical Tibotec Pharmaceuticals
Publication of HRP20110883T1 publication Critical patent/HRP20110883T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HR20110883T 2006-06-06 2007-06-06 Postupak za pripremanje raspršivanjem osušenih formulacija tmc125 HRP20110883T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06115029 2006-06-06
PCT/EP2007/055607 WO2007141308A1 (en) 2006-06-06 2007-06-06 Process for preparing spray dried formulations of tmc125

Publications (1)

Publication Number Publication Date
HRP20110883T1 true HRP20110883T1 (hr) 2012-01-31

Family

ID=37179187

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20110883T HRP20110883T1 (hr) 2006-06-06 2007-06-06 Postupak za pripremanje raspršivanjem osušenih formulacija tmc125

Country Status (26)

Country Link
US (2) US20090197903A1 (da)
EP (1) EP2029110B1 (da)
JP (1) JP5089685B2 (da)
KR (1) KR101179905B1 (da)
CN (1) CN101453989B (da)
AT (1) ATE522202T1 (da)
AU (1) AU2007255418C1 (da)
BR (1) BRPI0712346B8 (da)
CA (1) CA2651665C (da)
CY (1) CY1112154T1 (da)
DK (1) DK2029110T3 (da)
EC (1) ECSP088938A (da)
ES (1) ES2372983T3 (da)
HR (1) HRP20110883T1 (da)
IL (1) IL195710A (da)
ME (1) ME01305B (da)
MX (1) MX2008015686A (da)
NO (1) NO343652B1 (da)
NZ (1) NZ572702A (da)
PL (1) PL2029110T3 (da)
PT (1) PT2029110E (da)
RS (1) RS52053B (da)
RU (1) RU2406502C2 (da)
SI (1) SI2029110T1 (da)
WO (1) WO2007141308A1 (da)
ZA (1) ZA200810345B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR065720A1 (es) 2007-03-14 2009-06-24 Tibotec Pharm Ltd Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
CA2728890C (en) 2008-04-02 2016-05-03 Astellas Pharma Inc. Amide derivative-containing pharmaceutical composition
EP2306980A2 (en) * 2008-06-30 2011-04-13 Tibotec Pharmaceuticals Powders for reconstitution
WO2013109354A2 (en) * 2011-12-07 2013-07-25 Texas Southern University Etravirine formulations and uses thereof
WO2014048783A1 (en) * 2012-09-27 2014-04-03 Basf Se A storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble vitamin e-derivative and at least one hydrophilic polymer
WO2019216700A1 (ko) * 2018-05-11 2019-11-14 주식회사 삼양사 고체 분산체, 이의 제조 방법, 이를 이용한 사슬 연장된 폴리우레탄 및 이를 포함하는 에폭시 수지 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2920956B2 (ja) * 1989-10-06 1999-07-19 藤沢薬品工業株式会社 ニルバジピン含有持続性錠剤
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
JPH107558A (ja) * 1996-06-19 1998-01-13 Eisai Co Ltd 溶解性改善製剤
JP3635238B2 (ja) 1998-11-10 2005-04-06 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｈｉｖの複製を阻害するピリミジン類
EP1027886B1 (en) * 1999-02-10 2008-07-09 Pfizer Products Inc. Pharmaceutical solid dispersions
DE19945982A1 (de) 1999-09-24 2001-03-29 Knoll Ag Geschwindigkeitsbestimmte Partikel
DE60025837T2 (de) * 1999-09-24 2006-11-02 Janssen Pharmaceutica N.V. Antivirale feste dispersionen
US6531158B1 (en) * 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients
JP2005523260A (ja) * 2002-02-01 2005-08-04 ファイザー・プロダクツ・インク 圧力ノズルを用いた均質噴霧乾燥固体非晶質薬剤分散体の製造方法
AU2002350719A1 (en) * 2002-11-29 2004-06-23 Janssen Pharmaceutica N.V. Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
CA2511385A1 (en) * 2002-12-19 2004-07-22 Pharmacia Corporation Non-hygroscopic formulation comprising a hydroscopic drug
CN1822843B (zh) * 2003-07-17 2010-04-28 泰博特克药品有限公司 制备含有抗病毒药物颗粒的方法
BRPI0417492A (pt) * 2003-12-09 2007-05-29 Pfizer composições compreendendo um inibidor de protease de hiv

Also Published As

Publication number Publication date
WO2007141308A1 (en) 2007-12-13
AU2007255418C1 (en) 2011-08-18
NZ572702A (en) 2011-09-30
CN101453989B (zh) 2012-06-13
US20090197903A1 (en) 2009-08-06
ATE522202T1 (de) 2011-09-15
BRPI0712346B8 (pt) 2021-05-25
KR20090024131A (ko) 2009-03-06
PT2029110E (pt) 2011-11-23
ES2372983T3 (es) 2012-01-30
IL195710A0 (en) 2009-09-01
ME01305B (me) 2012-04-30
PL2029110T3 (pl) 2012-03-30
HK1129579A1 (en) 2009-12-04
NO343652B1 (no) 2019-04-29
ZA200810345B (en) 2012-05-30
MX2008015686A (es) 2009-01-12
EP2029110A1 (en) 2009-03-04
JP5089685B2 (ja) 2012-12-05
RU2008152411A (ru) 2010-07-20
AU2007255418A1 (en) 2007-12-13
SI2029110T1 (sl) 2012-01-31
CN101453989A (zh) 2009-06-10
AU2007255418B2 (en) 2010-12-23
BRPI0712346A2 (pt) 2012-07-17
RS52053B (sr) 2012-04-30
KR101179905B1 (ko) 2012-09-07
US9603803B2 (en) 2017-03-28
JP2009539804A (ja) 2009-11-19
DK2029110T3 (da) 2011-12-19
CA2651665A1 (en) 2007-12-13
US20120208834A1 (en) 2012-08-16
CY1112154T1 (el) 2015-12-09
RU2406502C2 (ru) 2010-12-20
IL195710A (en) 2014-02-27
NO20090061L (no) 2009-01-06
EP2029110B1 (en) 2011-08-31
ECSP088938A (es) 2009-01-30
CA2651665C (en) 2010-04-27
BRPI0712346B1 (pt) 2020-09-29

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