BRPI0417492A - composições compreendendo um inibidor de protease de hiv - Google Patents
composições compreendendo um inibidor de protease de hivInfo
- Publication number
- BRPI0417492A BRPI0417492A BRPI0417492-5A BRPI0417492A BRPI0417492A BR PI0417492 A BRPI0417492 A BR PI0417492A BR PI0417492 A BRPI0417492 A BR PI0417492A BR PI0417492 A BRPI0417492 A BR PI0417492A
- Authority
- BR
- Brazil
- Prior art keywords
- hiv protease
- compositions
- protease inhibitor
- hiv
- phenylbutanoyl
- Prior art date
Links
- 229940122440 HIV protease inhibitor Drugs 0.000 title abstract 2
- 239000004030 hiv protease inhibitor Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 108010010369 HIV Protease Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Medicinal Preparation (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
Abstract
COMPOSIçõES COMPREENDENDO UM INIBIDOR DE PROTEASE DE HIV. A presente invenção refere-se a composições farmacêuticas compreendendo (4R)-N-alil-3-{(2S,3S)-2-hidróxi-2-metibenzoil)amino!-4-fenilbutanoil}- 5,5-dimetil-1,3-tiazolidina-4-carboxamida,ou um seu solvato ou sal farmaceuticamente aceitável, a seus métodos de preparação, a seu uso na inibição da enzima de protease de HIV, e a uso na fabricação de um medicamento para o tratamento de mamíferos infectados por HIV, tais como seres humanos.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52838103P | 2003-12-09 | 2003-12-09 | |
| US54235204P | 2004-02-06 | 2004-02-06 | |
| US61012304P | 2004-09-14 | 2004-09-14 | |
| PCT/IB2004/003921 WO2005056542A1 (en) | 2003-12-09 | 2004-11-26 | Compositions comprising an hiv protease inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0417492A true BRPI0417492A (pt) | 2007-05-29 |
Family
ID=34682169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0417492-5A BRPI0417492A (pt) | 2003-12-09 | 2004-11-26 | composições compreendendo um inibidor de protease de hiv |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050129772A1 (pt) |
| EP (1) | EP1694657A1 (pt) |
| JP (1) | JP2007513937A (pt) |
| BR (1) | BRPI0417492A (pt) |
| CA (1) | CA2547404A1 (pt) |
| WO (1) | WO2005056542A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003000226A2 (en) * | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions containing polymer and drug assemblies |
| CN1681479A (zh) * | 2002-08-12 | 2005-10-12 | 辉瑞产品公司 | 半有序药物和聚合物的药物组合物 |
| US20060009469A1 (en) * | 2004-05-28 | 2006-01-12 | Leonore Witchey-Lakshmanan | Particulate-stabilized injectable pharmacutical compositions of posaconazole |
| ATE522202T1 (de) * | 2006-06-06 | 2011-09-15 | Tibotec Pharm Ltd | Verfahren zur herstellung von sprühgetrockneten formulierungen von tmc125 |
| EP2109424A4 (en) * | 2007-01-19 | 2015-04-08 | Univ Utah Res Found | BIODEGRADABLE INTRAVAGINAL DEVICE FOR RELEASING THERAPEUTICS |
| CN111378013B (zh) * | 2018-12-29 | 2023-04-25 | 上海天伟生物制药有限公司 | 一种高纯度环肽化合物的制备方法 |
| WO2020146788A1 (en) * | 2019-01-11 | 2020-07-16 | University Of Washington | Combination pharmaceutical compositions and methods thereof |
| US20230138752A1 (en) * | 2021-11-03 | 2023-05-04 | Purdue Research Foundation | Plasticizers to improve release performance of amorphous solid dispersions |
| CN116650497B (zh) * | 2022-09-30 | 2025-04-29 | 广州帝奇医药技术有限公司 | 一种抗病毒药物组合物及其制备工艺与应用 |
| CN117159782B (zh) * | 2023-10-12 | 2024-03-08 | 湖南玉津医疗科技有限公司 | 一种多孔海绵状止血敷料及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
| DE3438830A1 (de) * | 1984-10-23 | 1986-04-30 | Rentschler Arzneimittel | Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung |
| DE4022648C2 (de) * | 1990-07-17 | 1994-01-27 | Nukem Gmbh | Verfahren und Vorrichtung zur Herstellung von kugelförmigen Teilchen aus flüssiger Phase |
| ES2111065T5 (es) * | 1991-04-16 | 2005-06-16 | Nippon Shinyaku Company, Limited | Procedimiento para producir una dispersion solida. |
| US5340591A (en) * | 1992-01-24 | 1994-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine |
| JP3265680B2 (ja) * | 1992-03-12 | 2002-03-11 | 大正製薬株式会社 | 経口製剤用組成物 |
| US5582855A (en) * | 1994-07-01 | 1996-12-10 | Fuisz Technologies Ltd. | Flash flow formed solloid delivery systems |
| DE19504832A1 (de) * | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
| US6558571B1 (en) * | 2000-08-11 | 2003-05-06 | Multisorb Technologies, Inc. | Oxygen-absorbing composition and method |
| HN2002000136A (es) * | 2001-06-11 | 2003-07-31 | Basf Ag | Inhibidores de la proteasa del virus hiv, compuestos que contienen a los mismos, sus usos farmaceuticos y los materiales para su sintesis |
| US8025899B2 (en) * | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
-
2004
- 2004-11-26 BR BRPI0417492-5A patent/BRPI0417492A/pt not_active Application Discontinuation
- 2004-11-26 JP JP2006543642A patent/JP2007513937A/ja active Pending
- 2004-11-26 WO PCT/IB2004/003921 patent/WO2005056542A1/en not_active Ceased
- 2004-11-26 CA CA002547404A patent/CA2547404A1/en not_active Abandoned
- 2004-11-26 EP EP04799020A patent/EP1694657A1/en not_active Withdrawn
- 2004-12-08 US US11/008,325 patent/US20050129772A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1694657A1 (en) | 2006-08-30 |
| US20050129772A1 (en) | 2005-06-16 |
| JP2007513937A (ja) | 2007-05-31 |
| WO2005056542A1 (en) | 2005-06-23 |
| CA2547404A1 (en) | 2005-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |