HRP20120046T1 - Nerameksan za uporabu kod liječenja subakutnog tinitusa - Google Patents

Nerameksan za uporabu kod liječenja subakutnog tinitusa Download PDF

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Publication number
HRP20120046T1
HRP20120046T1 HR20120046T HRP20120046T HRP20120046T1 HR P20120046 T1 HRP20120046 T1 HR P20120046T1 HR 20120046 T HR20120046 T HR 20120046T HR P20120046 T HRP20120046 T HR P20120046T HR P20120046 T1 HRP20120046 T1 HR P20120046T1
Authority
HR
Croatia
Prior art keywords
neramexane
pharmaceutically acceptable
acceptable salt
use according
tinnitus
Prior art date
Application number
HR20120046T
Other languages
English (en)
Croatian (hr)
Inventor
Ellers-Lenz Barbara
Rosenberg Tanja
Krueger Hagen
Althaus Michael
Original Assignee
Merz Pharma Gmbh & Co. Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co. Kgaa filed Critical Merz Pharma Gmbh & Co. Kgaa
Publication of HRP20120046T1 publication Critical patent/HRP20120046T1/hr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Percussion Or Vibration Massage (AREA)
HR20120046T 2007-09-12 2008-09-10 Nerameksan za uporabu kod liječenja subakutnog tinitusa HRP20120046T1 (hr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US99339607P 2007-09-12 2007-09-12
EP07253630 2007-09-12
US6708308P 2008-02-25 2008-02-25
US6693108P 2008-02-25 2008-02-25
US6702608P 2008-02-25 2008-02-25
EP08004778 2008-03-14
EP08004777 2008-03-14
EP08004776 2008-03-14
PCT/EP2008/007421 WO2009033652A1 (fr) 2007-09-12 2008-09-10 Dérivés de 1-amino-alkylcyclohexane pour le traitement de l'acouphène cochléaire

Publications (1)

Publication Number Publication Date
HRP20120046T1 true HRP20120046T1 (hr) 2012-02-29

Family

ID=40451596

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20120046T HRP20120046T1 (hr) 2007-09-12 2008-09-10 Nerameksan za uporabu kod liječenja subakutnog tinitusa

Country Status (21)

Country Link
US (6) US9498450B2 (fr)
EP (6) EP2200598A1 (fr)
JP (6) JP5563460B2 (fr)
KR (4) KR20100052556A (fr)
CN (4) CN101801366A (fr)
AR (3) AR070026A1 (fr)
AT (1) ATE532507T1 (fr)
AU (4) AU2008298018C1 (fr)
BR (2) BRPI0816690A2 (fr)
CA (4) CA2699207A1 (fr)
DK (1) DK2200600T3 (fr)
ES (5) ES2596262T3 (fr)
HR (1) HRP20120046T1 (fr)
MX (4) MX2010002733A (fr)
PL (1) PL2200600T3 (fr)
PT (1) PT2200600E (fr)
RU (1) RU2011137131A (fr)
SI (1) SI2200600T1 (fr)
TW (3) TW200927087A (fr)
WO (4) WO2009033651A1 (fr)
ZA (4) ZA201001264B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101801366A (zh) * 2007-09-12 2010-08-11 莫茨药物股份两合公司 用于neramexane的逐步增量包装和其在治疗内耳病中的用途
US20110294890A1 (en) 2010-05-28 2011-12-01 Merz Pharma Gmbh & Co. Kgaa Neramexane for the treatment or prevention of inner ear disorders
JP2013529604A (ja) * 2010-06-24 2013-07-22 メルツ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト アウフ アクティーン ネラメキサン複数単位剤形
EP2665474A1 (fr) * 2011-01-20 2013-11-27 Merz Pharma GmbH & Co. KGaA Néramexane pour le traitement ou la prévention de l'acouphène relatif au stress ou à une perte d'audition aiguë
US20160129084A1 (en) * 2013-03-06 2016-05-12 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure
SG11201608630SA (en) * 2014-04-28 2016-11-29 Kyorin Seiyaku Kk Drug for treatment of tinnitus patients
EA201692163A1 (ru) * 2014-04-28 2017-03-31 Керин Фармасьютикал Ко., Лтд. Лекарственное средство для лечения пациентов с тиннитусом
KR102441249B1 (ko) 2014-10-23 2022-09-08 아레나 파마슈티칼스, 인크. Ｐｇｉ2 수용체 관련 병태의 치료 방법
SI3297628T1 (sl) * 2015-05-18 2021-10-29 Sensorion Azasetron za uporabo pri zdravljenju izgube sluha
KR101893604B1 (ko) 2015-08-27 2018-08-30 경희대학교 산학협력단 칸디다 유틸리스 추출물을 포함하는 난청의 예방 또는 치료용 조성물
CN105924362B (zh) * 2016-02-05 2018-08-17 上海龙翔生物医药开发有限公司 芳香环丙基胺类化合物、其药学上可接受的盐、其制备方法及其用途
IL268997B2 (en) 2017-03-01 2023-09-01 Arena Pharm Inc Preparations containing pgi2 receptor agonists and processes for their preparation
US12433865B2 (en) 2018-05-16 2025-10-07 Arena Pharmaceuticals, Inc. Compositions comprising PGI2-receptor agonists and processes for the preparation thereof
KR102268893B1 (ko) 2020-01-16 2021-06-24 경북대학교 산학협력단 림노트릭스 속 knua002 균주를 포함하는 난청의 예방 또는 치료용 조성물
CN111477199B (zh) * 2020-04-02 2021-11-30 北京瑞迪欧文化传播有限责任公司 一种嵌入式音乐控制系统
EP4297708A4 (fr) 2021-09-09 2024-08-28 Samsung Electronics Co., Ltd. Gestion de distribution de contenu audio

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6024983A (en) 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
US4849222A (en) 1987-03-24 1989-07-18 The Procter & Gamble Company Mixtures for treating hypercholesterolemia
JP2670680B2 (ja) 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法
US5288502A (en) 1991-10-16 1994-02-22 The University Of Texas System Preparation and uses of multi-phase microspheres
EP0724432B1 (fr) 1993-10-22 2002-09-18 Genentech, Inc. Compositions et procedes de microencapsulation d'antigenes a utiliser comme vaccins
DE19528388A1 (de) * 1995-08-02 1997-02-06 Hans Peter Prof Dr Med Zenner Verwendung von Adamantan-Derivaten zur Behandlung von Erkrankungen des Innenohrs
AU4424697A (en) 1996-09-11 1998-04-02 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The The use of functional n-methyl-d-aspartate antagonists to ameliorate or prevent aminoglycoside-induced ototoxicity
US6071966A (en) 1997-06-30 2000-06-06 Merz + Co. Gmbh & Co. 1-amino-alkylcyclohexane NMDA receptor antagonists
UA61962C2 (uk) * 1997-06-30 2003-12-15 Мерц Фарма Гмбх Унд Ко. Кгаа Сполука 1-аміноалкілциклогексану, фармацевтична композиція на її основі та спосіб лікування
MXPA02009659A (es) * 2000-04-26 2003-03-10 Warner Lambert Co Derivado de ciclohexilamina como subtipo de los antagonistas del receptor selectivo nmda.
DE10048969A1 (de) * 2000-08-23 2002-03-14 Mueller Schwefe Gerhard Verwendung von Flupirtin zur Tinnitusbehandlung
US20030236288A1 (en) * 2002-02-28 2003-12-25 Karl Schoenafinger Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase
JP2004021734A (ja) 2002-06-18 2004-01-22 Nokia Corp キーパッドおよびキーパッドシステム
US7086532B2 (en) * 2003-07-16 2006-08-08 Allergan, Inc. Titration/compliance pack with increasing doses
JP2006502158A (ja) * 2002-09-06 2006-01-19 デュレクト コーポレーション グルタメート媒介神経伝達のモジュレーターの内耳への送達
DE10252665A1 (de) 2002-11-11 2004-06-03 Grünenthal GmbH 4-Aminomethyl-1-aryl-cyclohexylamin-Derivate
UA80055C2 (en) * 2003-05-27 2007-08-10 Forest Laboratories Combination of nmda-receptor antagonist and selective inhibitor of serotonin reuptake for a depression and other pscihiatric disorders treatment
AR046314A1 (es) * 2003-11-05 2005-11-30 Merz Pharma Gmbh & Co Kgaa Composiciones que comprenden ciclohexilaminas y aminoadamantanos
US20060002999A1 (en) 2004-06-17 2006-01-05 Forest Laboratories, Inc. Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane
BRPI0512263A (pt) * 2004-06-17 2008-02-26 Merz Pharma Gmbh & Co Kgaa formulações de liberação imediata de formas de dosagem oral de memantina
US20060205822A1 (en) * 2004-12-22 2006-09-14 Forest Laboratories, Inc. 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect
JP2008537684A (ja) * 2005-01-24 2008-09-25 ニューロシステック コーポレイション 内耳およびその他の組織へ治療薬および／またはその他の薬剤を送達するための装置および方法
EP2932971A1 (fr) * 2005-03-04 2015-10-21 Otonomy, Inc. Formulations de la ketamine
TWI265036B (en) * 2005-04-29 2006-11-01 Guo-Ming Huang Safety injector and method of operating the same
US8062205B2 (en) * 2005-05-18 2011-11-22 Gt Urological, Llc Drug elution for implantable incontinence devices
CN1896729A (zh) 2005-07-15 2007-01-17 复旦大学附属中山医院 纳米药物自组装双稳态量子线阵列及其制备方法
US20070141148A1 (en) * 2005-11-30 2007-06-21 Merz Pharma Gmbh & Co. Kgaa Neramexane MR matrix tablet
TW200819458A (en) * 2006-06-23 2008-05-01 Merz Pharma Gmbh & Co Kgaa Metabotropic glutamate receptor modulators
CN101801366A (zh) * 2007-09-12 2010-08-11 莫茨药物股份两合公司 用于neramexane的逐步增量包装和其在治疗内耳病中的用途
TW201010691A (en) * 2008-06-12 2010-03-16 Merz Pharma Gmbh & Co Kgaa 1-amino-alkylcyclohexane derivatives for the treatment of sleep disorders
TW201006463A (en) * 2008-06-26 2010-02-16 Merz Pharma Gmbh & Co Kgaa Pharmaceutical compositions comprising aminocyclohexane derivatives
KR20110050739A (ko) * 2008-09-10 2011-05-16 메르츠 파마 게엠베하 운트 코. 카가아 이명에서 인지 장애의 치료를 위한 １-아미노-알킬시클로헥산 유도체
US20110294890A1 (en) * 2010-05-28 2011-12-01 Merz Pharma Gmbh & Co. Kgaa Neramexane for the treatment or prevention of inner ear disorders
EP2665474A1 (fr) * 2011-01-20 2013-11-27 Merz Pharma GmbH & Co. KGaA Néramexane pour le traitement ou la prévention de l'acouphène relatif au stress ou à une perte d'audition aiguë

Also Published As

Publication number Publication date
ZA201001263B (en) 2011-07-27
WO2009033651A1 (fr) 2009-03-19
PL2200600T3 (pl) 2012-04-30
JP5563460B2 (ja) 2014-07-30
US8877814B2 (en) 2014-11-04
TW200922544A (en) 2009-06-01
WO2009033649A1 (fr) 2009-03-19
ES2510565T3 (es) 2014-10-21
JP5613053B2 (ja) 2014-10-22
ZA201001261B (en) 2011-08-31
EP2203163B1 (fr) 2014-08-27
AU2008298018B2 (en) 2012-01-19
AU2008298018C1 (en) 2012-08-16
CN101801366A (zh) 2010-08-11
CA2699213A1 (fr) 2009-03-19
AU2008298017B2 (en) 2012-03-01
PT2200600E (pt) 2012-02-17
AU2008298015A1 (en) 2009-03-19
ES2596262T3 (es) 2017-01-05
JP5563461B2 (ja) 2014-07-30
CN101801365A (zh) 2010-08-11
AU2008298018A1 (en) 2009-03-19
TW200918042A (en) 2009-05-01
CN101835469A (zh) 2010-09-15
RU2011137131A (ru) 2013-03-20
EP2200598A1 (fr) 2010-06-30
AU2008298016B2 (en) 2012-02-02
CA2699207A1 (fr) 2009-03-19
ZA201001264B (en) 2011-07-27
AR071728A1 (es) 2010-07-14
EP2203163A1 (fr) 2010-07-07
WO2009033652A1 (fr) 2009-03-19
EP2386299B1 (fr) 2016-07-13
BRPI0816690A2 (pt) 2016-11-01
JP2010539116A (ja) 2010-12-16
DK2200600T3 (da) 2012-01-23
US20110077304A1 (en) 2011-03-31
JP2010539118A (ja) 2010-12-16
MX2010002736A (es) 2010-04-01
ES2377253T3 (es) 2012-03-23
BRPI0816712A2 (pt) 2016-11-08
KR20100052556A (ko) 2010-05-19
CA2699209A1 (fr) 2009-03-19
JP2014221766A (ja) 2014-11-27
KR20100052559A (ko) 2010-05-19
WO2009033650A1 (fr) 2009-03-19
JP5784189B2 (ja) 2015-09-24
EP2548552B1 (fr) 2015-11-18
US20100298441A1 (en) 2010-11-25
JP5612473B2 (ja) 2014-10-22
MX2010002733A (es) 2010-04-09
US9468610B2 (en) 2016-10-18
EP2200599B1 (fr) 2016-08-31
US20170027885A1 (en) 2017-02-02
ZA201001262B (en) 2011-07-27
AU2008298017A1 (en) 2009-03-19
MX2010002734A (es) 2010-04-01
AU2008298015B2 (en) 2012-03-22
JP5784188B2 (ja) 2015-09-24
AU2008298016A1 (en) 2009-03-19
KR20100052557A (ko) 2010-05-19
CA2699210A1 (fr) 2009-03-19
AR070026A1 (es) 2010-03-10
ES2562709T3 (es) 2016-03-07
KR20100052558A (ko) 2010-05-19
EP2386299A2 (fr) 2011-11-16
ES2604945T3 (es) 2017-03-10
TW200927087A (en) 2009-07-01
JP2014221767A (ja) 2014-11-27
AR070025A1 (es) 2010-03-10
JP2010539115A (ja) 2010-12-16
EP2386299A3 (fr) 2012-05-02
US20110086916A1 (en) 2011-04-14
US9498450B2 (en) 2016-11-22
US20100298440A1 (en) 2010-11-25
ATE532507T1 (de) 2011-11-15
MX2010002735A (es) 2010-04-01
EP2200599A1 (fr) 2010-06-30
EP2548552A3 (fr) 2013-10-16
EP2548552A2 (fr) 2013-01-23
CN101795679A (zh) 2010-08-04
EP2200600B1 (fr) 2011-11-09
EP2200600A1 (fr) 2010-06-30
US20150018425A1 (en) 2015-01-15
SI2200600T1 (sl) 2012-03-30
JP2010539117A (ja) 2010-12-16

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