HRP20120583T1 - Oblici flupentiksola - Google Patents

Oblici flupentiksola Download PDF

Info

Publication number
HRP20120583T1
HRP20120583T1 HRP20120583AT HRP20120583T HRP20120583T1 HR P20120583 T1 HRP20120583 T1 HR P20120583T1 HR P20120583A T HRP20120583A T HR P20120583AT HR P20120583 T HRP20120583 T HR P20120583T HR P20120583 T1 HRP20120583 T1 HR P20120583T1
Authority
HR
Croatia
Prior art keywords
pharmaceutically acceptable
flupentixol
cyclodextrin
acceptable salt
free base
Prior art date
Application number
HRP20120583AT
Other languages
English (en)
Croatian (hr)
Inventor
Enok Olsen Flemming
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of HRP20120583T1 publication Critical patent/HRP20120583T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)
HRP20120583AT 2010-04-06 2012-07-12 Oblici flupentiksola HRP20120583T1 (hr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10159137A EP2374450B8 (fr) 2010-04-06 2010-04-06 Compositions de flupentixol

Publications (1)

Publication Number Publication Date
HRP20120583T1 true HRP20120583T1 (hr) 2012-08-31

Family

ID=42372336

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20120583AT HRP20120583T1 (hr) 2010-04-06 2012-07-12 Oblici flupentiksola

Country Status (11)

Country Link
EP (1) EP2374450B8 (fr)
CY (1) CY1113065T1 (fr)
DK (1) DK2374450T3 (fr)
ES (1) ES2387191T3 (fr)
HR (1) HRP20120583T1 (fr)
ME (1) ME01439B (fr)
PL (1) PL2374450T3 (fr)
PT (1) PT2374450E (fr)
RS (1) RS52461B (fr)
SI (1) SI2374450T1 (fr)
SM (1) SMT201200040B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104288153B (zh) * 2014-09-19 2019-10-29 四川海思科制药有限公司 一种氟哌噻吨美利曲辛药物组合物及其制备方法
CN105663062B (zh) * 2016-02-17 2019-01-29 南京卓康医药科技有限公司 一种氟哌噻吨美利曲辛药物组合物及其制备方法
CN108498470A (zh) * 2017-02-24 2018-09-07 重庆圣华曦药业股份有限公司 一种氟哌噻吨美利曲辛药物组合物及其制备方法
CN109771386B (zh) * 2019-01-10 2021-10-08 广东赛烽医药科技有限公司 一种氟哌噻吨美利曲辛片剂及其制备方法
CN109674754B (zh) * 2019-01-10 2021-10-08 广东赛烽医药科技有限公司 一种氟哌噻吨美利曲辛药物组合物及其制剂
CN112300119B (zh) * 2019-08-02 2024-04-16 苏州恩华生物医药科技有限公司 美利曲辛与氟哌噻吨共晶及其制备方法
EP4622626A1 (fr) * 2022-11-24 2025-10-01 H. Lundbeck A/S Composition comprenant du zuclopenthixol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1210890B (de) 1960-03-07 1966-02-17 Smith & Kline & French Lab Verfahren zur Herstellung von Trifluormethyl-xanthen- oder thioxanthenderivaten
NL274885A (fr) 1960-09-16
JPH10194996A (ja) * 1996-12-25 1998-07-28 Janssen Pharmaceut Nv アシル化シクロデキストリン含有製薬組成物
CN100560064C (zh) * 2007-09-04 2009-11-18 上海慈瑞医药科技有限公司 一种氟哌噻吨美利曲辛胶囊的制备方法

Also Published As

Publication number Publication date
EP2374450B1 (fr) 2012-06-27
PL2374450T3 (pl) 2012-10-31
SMT201200040B (it) 2012-10-31
RS52461B (sr) 2013-02-28
EP2374450A1 (fr) 2011-10-12
ME01439B (fr) 2013-12-20
ES2387191T3 (es) 2012-09-17
SI2374450T1 (sl) 2012-09-28
PT2374450E (pt) 2012-07-26
DK2374450T3 (da) 2012-07-23
CY1113065T1 (el) 2016-04-13
EP2374450B8 (fr) 2012-10-17

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