HRP930814A2 - Tachykinin antagonists tricyclic compounds - Google Patents

Tachykinin antagonists tricyclic compounds

Info

Publication number: HRP930814A2
Authority: HR; Croatia
Prior art keywords: tricyclic compounds; tachykinin antagonists; group; compounds; 3alkyl
Prior art date: 1992-04-15

Application number

HRFI92A000089A

Other languages

English (en)

Inventor

Vincenzo Pavone

Angelina Lombardi

Carlo Pedone

Carlo Alberto Maggi

Laura Quartara

Original Assignee

Menarini Ind Farmacheutice Riu

Guidotti & C Spa Labor

Malesci Sas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-15

Filing date

1993-04-14

Publication date

1996-12-31

1993-04-14 Application filed by Menarini Ind Farmacheutice Riu, Guidotti & C Spa Labor, Malesci Sas filed Critical Menarini Ind Farmacheutice Riu

1996-12-31 Publication of HRP930814A2 publication Critical patent/HRP930814A2/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

HRFI92A000089A 1992-04-15 1993-04-14 Tachykinin antagonists tricyclic compounds HRP930814A2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITFI920089A IT1262902B (it)	1992-04-15	1992-04-15	Composti triciclici antagonisti delle tachichinine, loro preparazione e loro uso in composizioni farmaceutiche.

Publications (1)

Publication Number	Publication Date
HRP930814A2 true HRP930814A2 (en)	1996-12-31

Family

ID=11350056

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRFI92A000089A HRP930814A2 (en)	1992-04-15	1993-04-14	Tachykinin antagonists tricyclic compounds

Country Status (28)

Country	Link
EP (1)	EP0636146B1 (de)
JP (1)	JPH08500331A (de)
KR (1)	KR950700935A (de)
CN (1)	CN1039126C (de)
AT (1)	ATE156135T1 (de)
AU (1)	AU671118B2 (de)
BG (1)	BG99110A (de)
BR (1)	BR9306248A (de)
CA (1)	CA2118253A1 (de)
CZ (1)	CZ254294A3 (de)
DE (1)	DE69312698T2 (de)
DK (1)	DK0636146T3 (de)
ES (1)	ES2105265T3 (de)
FI (1)	FI944838A7 (de)
GR (1)	GR3024348T3 (de)
HR (1)	HRP930814A2 (de)
HU (1)	HUT70189A (de)
IL (1)	IL105381A (de)
IT (1)	IT1262902B (de)
MX (1)	MX9302161A (de)
NO (1)	NO943861D0 (de)
NZ (1)	NZ251969A (de)
RO (1)	RO112872B1 (de)
RU (1)	RU94045890A (de)
SK (1)	SK124294A3 (de)
TW (1)	TW234718B (de)
WO (1)	WO1993021227A1 (de)
ZA (1)	ZA932644B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1277835B1 (it) *	1995-03-13	1997-11-12	Menarini Farma Ind	Composti biciclici, loro preparazione ed uso in composizioni farmaceutiche
IT1283171B1 (it) *	1996-03-01	1998-04-16	Interdipartimentale Di Ricerca	Composti solubili antagonisti delle tachichinine loro preparazione e loro uso in composizioni farmaceutiche
IT1291776B1 (it)	1997-02-07	1999-01-21	Menarini Ricerche Spa	Composti monociclici a quattro residui bifunzionali, aventi azione nk-2 antagonista
IT1307809B1 (it)	1999-10-21	2001-11-19	Menarini Ricerche Spa	Composti monociclici basici ad azione nk-2 antagonista, processi difabbricazione e formulazioni che li contengono.
EP1297826A1 (de) *	2001-09-27	2003-04-02	Menarini Ricerche S.p.A.	Pharmazeutische Zusammensetzung zur nasalen Verabreichung enthaltend einen NK-2 Antagonisten

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8807246D0 (en) *	1988-03-25	1988-04-27	Merck Sharp & Dohme	Therapeutic agents
DE3915361A1 (de) *	1989-05-11	1990-11-15	Merck Patent Gmbh	Cyclopeptide

1992
- 1992-04-15 IT ITFI920089A patent/IT1262902B/it active IP Right Grant
1993
- 1993-04-13 SK SK1242-94A patent/SK124294A3/sk unknown
- 1993-04-13 RU RU94045890/04A patent/RU94045890A/ru unknown
- 1993-04-13 EP EP93911459A patent/EP0636146B1/de not_active Expired - Lifetime
- 1993-04-13 CZ CZ942542A patent/CZ254294A3/cs unknown
- 1993-04-13 AT AT93911459T patent/ATE156135T1/de not_active IP Right Cessation
- 1993-04-13 ES ES93911459T patent/ES2105265T3/es not_active Expired - Lifetime
- 1993-04-13 JP JP5517974A patent/JPH08500331A/ja active Pending
- 1993-04-13 DE DE69312698T patent/DE69312698T2/de not_active Expired - Fee Related
- 1993-04-13 RO RO94-01666A patent/RO112872B1/ro unknown
- 1993-04-13 AU AU40395/93A patent/AU671118B2/en not_active Ceased
- 1993-04-13 BR BR9306248A patent/BR9306248A/pt not_active Application Discontinuation
- 1993-04-13 FI FI944838A patent/FI944838A7/fi not_active Application Discontinuation
- 1993-04-13 HU HU9402977A patent/HUT70189A/hu unknown
- 1993-04-13 WO PCT/EP1993/000893 patent/WO1993021227A1/en not_active Ceased
- 1993-04-13 NZ NZ251969A patent/NZ251969A/en unknown
- 1993-04-13 DK DK93911459.1T patent/DK0636146T3/da active
- 1993-04-13 CA CA002118253A patent/CA2118253A1/en not_active Abandoned
- 1993-04-14 CN CN93104453A patent/CN1039126C/zh not_active Expired - Fee Related
- 1993-04-14 IL IL105381A patent/IL105381A/en not_active IP Right Cessation
- 1993-04-14 MX MX9302161A patent/MX9302161A/es unknown
- 1993-04-14 HR HRFI92A000089A patent/HRP930814A2/xx not_active Application Discontinuation
- 1993-04-15 TW TW082102894A patent/TW234718B/zh active
- 1993-04-15 ZA ZA932644A patent/ZA932644B/xx unknown
1994
- 1994-10-11 KR KR1019940703613A patent/KR950700935A/ko not_active Withdrawn
- 1994-10-13 NO NO943861A patent/NO943861D0/no unknown
- 1994-10-14 BG BG99110A patent/BG99110A/bg unknown
1997
- 1997-08-01 GR GR970401994T patent/GR3024348T3/el unknown

Also Published As

Publication number	Publication date
NO943861L (no)	1994-10-13
HU9402977D0 (en)	1995-02-28
NO943861D0 (no)	1994-10-13
HUT70189A (en)	1995-09-28
CN1039126C (zh)	1998-07-15
DK0636146T3 (da)	1998-02-23
DE69312698T2 (de)	1997-12-04
KR950700935A (ko)	1995-02-20
SK124294A3 (en)	1995-07-11
ATE156135T1 (de)	1997-08-15
CN1080916A (zh)	1994-01-19
CZ254294A3 (en)	1995-07-12
RO112872B1 (ro)	1998-01-30
TW234718B (de)	1994-11-21
ITFI920089A1 (it)	1993-10-15
EP0636146A1 (de)	1995-02-01
EP0636146B1 (de)	1997-07-30
ES2105265T3 (es)	1997-10-16
JPH08500331A (ja)	1996-01-16
CA2118253A1 (en)	1993-10-28
BR9306248A (pt)	1998-06-23
WO1993021227A1 (en)	1993-10-28
NZ251969A (en)	1997-12-19
ITFI920089A0 (it)	1992-04-15
IL105381A (en)	1998-02-22
ZA932644B (en)	1993-10-22
BG99110A (bg)	1995-09-29
FI944838L (fi)	1994-10-14
MX9302161A (es)	1994-05-31
FI944838A0 (fi)	1994-10-14
RU94045890A (ru)	1996-09-10
GR3024348T3 (en)	1997-11-28
AU671118B2 (en)	1996-08-15
DE69312698D1 (de)	1997-09-04
AU4039593A (en)	1993-11-18
FI944838A7 (fi)	1994-10-14
IT1262902B (it)	1996-07-22

Legal Events

Date	Code	Title	Description
1996-12-31	A1OB	Publication of a patent application
1998-03-18	ODBC	Application rejected

Publication	Publication Date	Title
ATE60759T1 (de)	1991-02-15	Bisdimethoxymethyl(trimethoxybenzyl)isochinolinium salze, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE3378053D1 (en)	1988-10-27	Nonapeptide and decapeptide analogs of lhrh useful as lhrh antagonists, their preparation and compositions containing them
IL112622A0 (en)	1995-05-26	Camptothecin derivatives, their preparation and pharmaceutical compositions containing them
ES8801277A1 (es)	1988-01-01	Procedimiento para preparar (1,2,4) triazolo (1,5-c) quinazolinas
SE8900863D0 (sv)	1989-03-10	Water soluble, nonionic cellulose ethers and their use in paints
DE69317877D1 (en)	1998-05-14	4''-deoxyerythromycinderivate
CA2237189A1 (en)	1997-07-17	3-azetidinylalkylpiperidines or -pyrrolidines as tachykinin antagonists
DE59005304D1 (de)	1994-05-19	Benzolsulfonamide und Verfahren zu ihrer Herstellung.
IL74745A0 (en)	1985-06-30	Substituted benzopyrans,their preparation and pharmaceutical compositions containing them
TW234718B (de)	1994-11-21
SE8207224L (sv)	1983-06-25	Nya aromatiska aminoalkoxiderivat, deras framstellning och deras terapeutiska anvendning
CA2111083A1 (en)	1993-01-07	Novel peptides, their preparation and use
IT1297205B1 (it)	1999-08-03	Composizioni farmaceutiche di somatostatina con assorbimento migliorato, loro preparazione e loro impiego
IL99233A0 (en)	1992-07-15	Phosphonopyrrolidine-and phosphonopiperidine-containing pseudopeptides of the statin type,their preparation and pharmaceutical compositions containing them
GEP20002271B (en)	2000-10-25	Bicyclic Tachykinins Antagonists, Pharmaceutical Composition on Its Basis and Their Use
ES2081763A1 (es)	1996-03-01	Forma puridicada de estreptograminas, su preparacion y las composiciones farmaceuticas que la contienen.
CA2032797A1 (en)	1991-06-22	Antithrombotic compounds
ATE37376T1 (de)	1988-10-15	Nonapeptid- und decapeptidanaloge von lhrh mit wirkung als lhrh antagonisten, ihre herstellung und diese enthaltende zusammensetzungen.
WO1999005106A8 (fr)	1999-04-15	Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse
NO941382L (no)	1994-10-17	Fremstilling av lignananaloger
RU94020401A (ru)	1995-08-20	СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ β -ФЕНИЛ-ИЗОСЕРИНА И ПРОИЗВОДНЫЕ b -ФЕНИЛ-ИЗОСЕРИНА
RU92004492A (ru)	1995-05-20	Сульфонимидамиды, способы их получения, фармацевтическая композиция
CA2165294A1 (en)	1995-01-12	An Iodinated Neuroprobe for Mapping Monoamine Reuptake Sites