HRP950077A2 - 5-vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids - Google Patents

5-vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids Download PDF

Info

Publication number
HRP950077A2
HRP950077A2 HRP4408212.6A HRP950077A HRP950077A2 HR P950077 A2 HRP950077 A2 HR P950077A2 HR P950077 A HRP950077 A HR P950077A HR P950077 A2 HRP950077 A2 HR P950077A2
Authority
HR
Croatia
Prior art keywords
methyl
hydrogen
alkyl
image
halogen
Prior art date
Application number
HRP4408212.6A
Other languages
English (en)
Croatian (hr)
Inventor
Thomas Himmler
Uwe Petersen
Klaus-Dieter Bremm
Rainer Endermann
Michael Stegemann
Heinz-Georg Wetzstein
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HRP950077A2 publication Critical patent/HRP950077A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/762—Organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/771—Organic compounds containing hetero rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
HRP4408212.6A 1994-03-11 1995-02-20 5-vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids HRP950077A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4408212A DE4408212A1 (de) 1994-03-11 1994-03-11 5-Vinyl- und 5-Ethinyl-chinolon- und -naphthyridon-carbonsäuren

Publications (1)

Publication Number Publication Date
HRP950077A2 true HRP950077A2 (en) 1997-08-31

Family

ID=6512492

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP4408212.6A HRP950077A2 (en) 1994-03-11 1995-02-20 5-vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids

Country Status (29)

Country Link
US (2) US5578604A (fr)
EP (1) EP0671391A1 (fr)
JP (1) JPH07285941A (fr)
KR (1) KR950032177A (fr)
CN (1) CN1111629A (fr)
AU (1) AU689189B2 (fr)
BG (1) BG62001B1 (fr)
CA (1) CA2144231A1 (fr)
CO (1) CO4340737A1 (fr)
CZ (1) CZ63895A3 (fr)
DE (1) DE4408212A1 (fr)
DZ (1) DZ1862A1 (fr)
EE (1) EE9500020A (fr)
FI (1) FI951101L (fr)
HR (1) HRP950077A2 (fr)
HU (1) HUT72071A (fr)
IL (1) IL112936A0 (fr)
LV (1) LV11469B (fr)
MA (1) MA23475A1 (fr)
NO (1) NO950936L (fr)
NZ (1) NZ270657A (fr)
PE (1) PE33895A1 (fr)
PL (1) PL307583A1 (fr)
RU (1) RU95103433A (fr)
SK (1) SK31695A3 (fr)
SV (1) SV1995000012A (fr)
TN (1) TNSN95017A1 (fr)
YU (1) YU15895A (fr)
ZA (1) ZA952008B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4427530A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
US6743594B1 (en) 1995-06-06 2004-06-01 Human Genome Sciences, Inc. Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
DE19652219A1 (de) * 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(1-Aminomethyl-2-oxa-7-azabicyclo[3.3.0]oct-7-yl)-chinolon- und naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
US6984499B2 (en) * 1997-10-02 2006-01-10 Idexx Laboratories, Inc. Method and apparatus for concurrently detecting pathogenic organisms and antimicrobial susceptibility
JP2003516988A (ja) * 1999-12-14 2003-05-20 ニューロサーチ、アクティーゼルスカブ 新規ヘテロアリール−ジアザビシクロアルカン類
US7175988B2 (en) 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
EP1397365B1 (fr) * 2001-06-01 2005-02-16 NeuroSearch A/S Heteroaryl-diazabicyclo-alcanes a titre de modulateurs du snc
EP1399479B1 (fr) * 2001-06-06 2009-09-16 Neurosearch A/S Recepteurs gaba a conduisant les cations et utilisation
US7393934B2 (en) 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
SI1666477T1 (sl) 2003-09-10 2013-10-30 Kyorin Pharmaceutical Co., Ltd. Derivati 7-(4-substituiran 3-ciklopropilaminometil-1-pirolidinil) kinolonkarboksilne kisline
CA2559809A1 (fr) 2004-03-12 2005-11-10 Human Genome Sciences, Inc. Anticorps diriges contre le polypeptide humain hdgnr10, un recepteur de chimiokine (ccr5) couple a des proteines-g
US8222407B2 (en) 2007-05-24 2012-07-17 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
CN103724262B (zh) * 2013-12-10 2016-05-18 广东省第二人民医院 一种氟喹诺酮银化合物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
EP0319906A3 (fr) * 1987-12-11 1990-05-02 Dainippon Pharmaceutical Co., Ltd. Dérivés de la quinoléine, procédé de leur préparation et agent antibactérien les contenant
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
AU5123690A (en) * 1989-03-13 1990-09-13 Bristol-Myers Squibb Company 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents
US5140033A (en) * 1989-04-03 1992-08-18 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
US5252734A (en) * 1989-04-03 1993-10-12 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
EP0593766B1 (fr) * 1991-05-28 2000-09-06 Daiichi Pharmaceutical Co., Ltd. Derive d'acide pyridonecarboxylique

Also Published As

Publication number Publication date
US5659038A (en) 1997-08-19
MA23475A1 (fr) 1995-10-01
AU1364995A (en) 1995-09-21
FI951101A0 (fi) 1995-03-09
PL307583A1 (en) 1995-09-18
DE4408212A1 (de) 1995-09-14
YU15895A (sh) 1998-05-15
KR950032177A (ko) 1995-12-20
EP0671391A1 (fr) 1995-09-13
NO950936L (no) 1995-09-12
FI951101A7 (fi) 1995-09-12
TNSN95017A1 (fr) 1996-02-06
BG99490A (en) 1996-01-31
JPH07285941A (ja) 1995-10-31
SV1995000012A (es) 1995-11-06
NZ270657A (en) 1997-01-29
LV11469B (en) 1996-12-20
IL112936A0 (en) 1995-06-29
ZA952008B (en) 1995-12-11
SK31695A3 (en) 1995-09-13
PE33895A1 (es) 1995-12-15
HU9500728D0 (en) 1995-04-28
FI951101L (fi) 1995-09-12
CN1111629A (zh) 1995-11-15
AU689189B2 (en) 1998-03-26
NO950936D0 (no) 1995-03-10
LV11469A (lv) 1996-08-20
CZ63895A3 (en) 1995-11-15
RU95103433A (ru) 1997-02-10
BG62001B1 (bg) 1998-12-30
EE9500020A (et) 1995-12-15
CO4340737A1 (es) 1996-07-30
CA2144231A1 (fr) 1995-09-12
DZ1862A1 (fr) 2002-02-17
HUT72071A (en) 1996-03-28
US5578604A (en) 1996-11-26

Similar Documents

Publication Publication Date Title
AU647627B2 (en) 7-Azaisoindolinyl-quinolone- and-naphthyridonecarboxylic acid derivatives
HRP950077A2 (en) 5-vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids
RU2077533C1 (ru) Производные хинолонкарбоновой кислоты, смесь их изомеров или отдельные изомеры, их фармацевтически приемлемые гидраты и соли, способ их получения
CZ396692A3 (en) Quinolonecarboxylic and naphthyridonecarboxylic acids derivatives
IE81144B1 (en) 7-(1-Pyrrolidinyl)-3-quinolone-and -naphthyridone-carboxylic acid derivatives processes for their preparation and substituted mono- and bicyclic pyrrolidine derivatives as intermediate products for their preparation and antibacterial agents and feed additives containing them
SK190192A3 (en) Quinoline carboxylic and naphthyridone carboxylic acid derivatives
IL108347A (en) Quinolone - and naphthyridonecarboxylic acid derivatives
US5468742A (en) 8-vinyl- and 9-ethinyl-quinolone-carboxylic acids
FI94524B (fi) Menetelmä terapeuttisesti käyttökelpoisten 1-syklopropyyli-6-fluori-7-(3,3-disubstituoitu-1-pyrrolidinyyli)-1,4-dihydro-4-okso-3-kinoliinikarboksyylihappojen valmistamiseksi
JPH04282384A (ja) ７−（２，７−ジアザビシクロ〔３．３．０〕オクチル）−３−キノロン及びナフチリドンカルボン酸誘導体
Mohammed et al. Synthesis and spectral characterization of 1, 5-naphthyridine derivatives through cross-coupling Suzuki reaction
SK137194A3 (en) 1-(2-fluorinecyclopropyl)-quinoline-carboxylic) and 1-(2- -florinecyclopropyl)-naphthyridonecarboxylic acid derivatives, method of their producing and their using in medicines
JPH06192262A (ja) ７−（アミノメチル−オキサ−７−アザ−ビシクロ［３．３．０］オクト−７−イル）キノロンカルボン酸および７−（アミノメチル−オキサ−７−アザ−ビシクロ［３．３．０］オクト−７−イル）ナフチリドンカルボン酸誘導体
IE19970856A1 (en) 7-(1-Pyrrolidinyl)-3-quinolone and naphthyridone carboxylic acid derivatives, method for their preparation and for substituted mono- and bicyclic pyrrolidine intermediates, and their antibacterial and feed additive compositions

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
OBST Application withdrawn