HRP960341A2 - New methods of using n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters) - Google Patents

New methods of using n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters) Download PDF

Info

Publication number
HRP960341A2
HRP960341A2 HR60/003,031A HRP960341A HRP960341A2 HR P960341 A2 HRP960341 A2 HR P960341A2 HR P960341 A HRP960341 A HR P960341A HR P960341 A2 HRP960341 A2 HR P960341A2
Authority
HR
Croatia
Prior art keywords
methylethyl
bis
phenyl
sulfamic acid
phenyl ester
Prior art date
Application number
HR60/003,031A
Other languages
English (en)
Croatian (hr)
Inventor
Brian Robert Krause
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of HRP960341A2 publication Critical patent/HRP960341A2/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HR60/003,031A 1995-08-04 1996-07-16 New methods of using n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters) HRP960341A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US303195P 1995-08-04 1995-08-04

Publications (1)

Publication Number Publication Date
HRP960341A2 true HRP960341A2 (en) 1998-02-28

Family

ID=21703764

Family Applications (1)

Application Number Title Priority Date Filing Date
HR60/003,031A HRP960341A2 (en) 1995-08-04 1996-07-16 New methods of using n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters)

Country Status (27)

Country Link
US (1) US6117909A (de)
EP (1) EP0841913B1 (de)
JP (1) JPH11510184A (de)
KR (1) KR19990036127A (de)
CN (1) CN1192140A (de)
AT (1) ATE232097T1 (de)
AU (1) AU716255B2 (de)
BG (1) BG63863B1 (de)
CA (1) CA2221729A1 (de)
CZ (1) CZ26198A3 (de)
DE (1) DE69626118T2 (de)
DK (1) DK0841913T3 (de)
EA (1) EA002435B1 (de)
EE (1) EE9800037A (de)
ES (1) ES2191762T3 (de)
GE (1) GEP20012511B (de)
HR (1) HRP960341A2 (de)
HU (1) HUP9900668A3 (de)
IL (1) IL122247A0 (de)
NO (1) NO980466L (de)
NZ (1) NZ312571A (de)
PL (1) PL185943B1 (de)
PT (1) PT841913E (de)
SK (1) SK12598A3 (de)
UA (1) UA46030C2 (de)
WO (1) WO1997005868A1 (de)
ZA (1) ZA966617B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1584333A3 (de) * 1998-01-28 2009-04-29 Warner-Lambert Company LLC Verwendung von Acetylcoenzyme A Inhibitoren zur Behandlung von Alzheimer
BR9912296A (pt) * 1998-07-21 2001-04-17 Warner Lambert Co Co-adminiostração de inibidores acat e mmp para o tratamento de lesões ateroscleróticas
IT1303249B1 (it) * 1998-10-23 2000-11-06 Dompe Spa Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono.
CN1414848A (zh) * 1999-11-05 2003-04-30 沃尼尔·朗伯公司 Acat抑制剂对斑块破裂的预防
CA2369967A1 (en) * 2001-02-12 2002-08-12 Joseph Anthony Cornicelli Methods of treating nuclear factor-kappa b mediated diseases and disorders
AR037097A1 (es) 2001-10-05 2004-10-20 Novartis Ag Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento
US6939224B2 (en) * 2002-03-12 2005-09-06 Igt Gaming device having varying risk player selections
EP3709986B1 (de) 2017-11-14 2023-11-01 Merck Sharp & Dohme LLC Neuartige substituierte biarylverbindungen als indolamin-2,3-dioxygenase(ido)-inhibitoren
BR112020008258B8 (pt) 2017-11-14 2023-01-31 Merck Sharp & Dohme Compostos de biarila substituída ou seus sais farmaceuticamente aceitáveis, sua composição e seu uso como inibidores de indoleamina 2,3-dioxigenase (ido)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5003106A (en) * 1983-07-19 1991-03-26 American Cyanamid Company Antiatherosclerotic ureas and thioureas
AU654688B2 (en) * 1990-10-30 1994-11-17 Warner-Lambert Company Oxysulfonyl carbamates
US5245068A (en) * 1990-10-30 1993-09-14 Warner-Lambert Company Oxysulfonyl carbamates
IL101785A0 (en) * 1991-05-10 1992-12-30 Fujisawa Pharmaceutical Co Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds

Also Published As

Publication number Publication date
BG102222A (en) 1998-09-30
UA46030C2 (uk) 2002-05-15
PL185943B1 (pl) 2003-09-30
EA002435B1 (ru) 2002-04-25
PL324908A1 (en) 1998-06-22
IL122247A0 (en) 1998-04-05
HUP9900668A3 (en) 2000-08-28
CA2221729A1 (en) 1997-02-20
SK12598A3 (en) 1999-02-11
EA199800176A1 (ru) 1998-10-29
HUP9900668A2 (hu) 1999-06-28
DE69626118D1 (de) 2003-03-13
US6117909A (en) 2000-09-12
KR19990036127A (ko) 1999-05-25
NO980466D0 (no) 1998-02-03
WO1997005868A1 (en) 1997-02-20
EP0841913B1 (de) 2003-02-05
EP0841913A1 (de) 1998-05-20
GEP20012511B (en) 2001-08-27
NZ312571A (en) 2000-07-28
EE9800037A (et) 1998-08-17
CZ26198A3 (cs) 1998-07-15
AU716255B2 (en) 2000-02-24
NO980466L (no) 1998-02-03
ATE232097T1 (de) 2003-02-15
DE69626118T2 (de) 2003-11-27
AU6454196A (en) 1997-03-05
BG63863B1 (bg) 2003-04-30
ZA966617B (en) 1997-02-18
CN1192140A (zh) 1998-09-02
ES2191762T3 (es) 2003-09-16
JPH11510184A (ja) 1999-09-07
DK0841913T3 (da) 2003-05-05
PT841913E (pt) 2003-06-30

Similar Documents

Publication Publication Date Title
RU2239456C2 (ru) Применение ингибиторов 3-гидрокси-3-метилглутарил-кофермент а-редуктазы в производстве лекарственного средства для лечения диабетической невропатии
CA2323839C (en) Treatment of neuropathy
KR100449604B1 (ko) 지질농도를 조절하는 제약 조성물 및 방법
US8048873B2 (en) Synergistic pharmaceutical combination for the prevention or treatment of diabetes
ES2334672T3 (es) Composicion farmaceutica que comprende un combinacion de metformina y una estatina.
JP2001508795A (ja) Ｍｔｐインヒビター単独またはこれと他のコレステロール降下薬を組合せて用いる心臓血管疾患の発病の危険を予防または軽減する方法
JP2008515905A (ja) 有機化合物の組合せ剤
CA2386990A1 (en) Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase
JP2002537258A5 (de)
ZA200505143B (en) Therapeutic formulations for the treatment of beta-amyloid related diseases
EP0841913B1 (de) Verwendung von sulfaminsäuren derivaten, acrylsulfonamiden oder sulfonylcarbonaten zur herstellung eines arzneimittels zur senkung des spiegels von lipoproteinen
AU661748B2 (en) Use of renin inhibitors for the treatment of glaucoma
RU2151597C1 (ru) Способ ингибирования пролиферации кератиноцитов
JP2001527551A (ja) Ｍｔｐインヒビターと脂溶性ビタミンの組合せおよび該組合せを用いる血清脂質レベルの降下法
JPWO1993005778A1 (ja) 血中脂質代謝改善剤
MXPA97009275A (en) Use of derivatives of sulfamic acid, acil sulfonamides or sulfonil carbamates for the manufacture of a medicinal product to reduce delipoprotei levels
JP2010520854A (ja) 高コレステロール血症の治療又は予防において使用するためのニトロキシド
AU2002301821B2 (en) Treatment of Neuropathy
HK1015278A (en) Use of sulfamic acid derivatives, acyl sulfonamides or sulfonyl carbamates for the manufacture of a medicament for lowering lipoprotein levels
Murakami et al. Hipolipidemic effects of HL-004, a novel ACAT inhibitor, in hamsters fed normal chow
Muls et al. Sequential fibrate and low-dose simvastatin treatment in 6422 patients with severe hypercholesterolemia: The Belgian General Practitioner's Study
Yanagita et al. Effects of ACAT inhibitors HL-004 and CI-976 on the synthesis and secretion of esterified cholesterol and on the de novo synthesis of cholesterol and glycerolipids in HepG2 cells

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODBC Application rejected