HU182267B - Process for preparing the antibiotic c-15003 p-3 - Google Patents
Process for preparing the antibiotic c-15003 p-3 Download PDFInfo
- Publication number
- HU182267B HU182267B HU803107A HU310780A HU182267B HU 182267 B HU182267 B HU 182267B HU 803107 A HU803107 A HU 803107A HU 310780 A HU310780 A HU 310780A HU 182267 B HU182267 B HU 182267B
- Authority
- HU
- Hungary
- Prior art keywords
- medium
- antibiotic
- added
- isobutyl
- isobutyl alcohol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/365—Nocardia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/872—Nocardia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17381979A JPS56102793A (en) | 1979-12-28 | 1979-12-28 | Preparation of antibiotic c-15003 p-3 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU182267B true HU182267B (en) | 1983-12-28 |
Family
ID=15967733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU803107A HU182267B (en) | 1979-12-28 | 1980-12-23 | Process for preparing the antibiotic c-15003 p-3 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4356265A (2) |
| EP (1) | EP0031430B1 (2) |
| JP (1) | JPS56102793A (2) |
| AT (1) | ATE5726T1 (2) |
| DE (1) | DE3066026D1 (2) |
| ES (1) | ES497033A0 (2) |
| HU (1) | HU182267B (2) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0293133A3 (en) * | 1987-05-26 | 1990-01-31 | Merck & Co. Inc. | Microorganisms and processes for the manufacture of antifungal tri-yne carbonates |
| US4977083A (en) * | 1988-04-11 | 1990-12-11 | Eli Lilly And Company | Processes for preparing A54145 compounds |
| JPH0839708A (ja) * | 1994-08-01 | 1996-02-13 | Teikoku Ink Seizo Kk | 非粘着性表面を有する物品およびその製造方法 |
| US6573074B2 (en) | 2000-04-12 | 2003-06-03 | Smithkline Beecham Plc | Methods for ansamitocin production |
| US6790954B2 (en) * | 2002-01-29 | 2004-09-14 | Immunogen, Inc. | Mutant Actinosynnema pretiosum strain with increased maytansinoid production |
| EP1627069A4 (en) * | 2002-08-08 | 2010-06-02 | Glaxosmithkline Llc | PROCESS FOR THE ISOLATION AND PURIFICATION OF ANSAMITOCINES |
| DE10248111A1 (de) * | 2002-10-15 | 2004-04-29 | Goldschmidt Ag | Verwendung von Photoinitiatoren vom Typ Hydroxyalkylphenon in strahlenhärtbaren Organopolysiloxanen für die Herstellung von abhäsiven Beschichtungen |
| US7432088B2 (en) * | 2003-05-08 | 2008-10-07 | Immunogen Inc. | Methods for the production of ansamitocins |
| WO2007067698A2 (en) * | 2005-12-08 | 2007-06-14 | Millennium Pharmaceuticals, Inc. | Isolation of ansamitocins |
| EP1806365A1 (en) | 2006-01-05 | 2007-07-11 | Boehringer Ingelheim International GmbH | Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them |
| WO2011014825A2 (en) * | 2009-07-31 | 2011-02-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Antiangiogenic small molecules and methods of use |
| CN101921817A (zh) * | 2010-09-07 | 2010-12-22 | 上海交通大学 | 安莎霉素发酵产量提高方法 |
| CN102732581B (zh) * | 2012-07-18 | 2014-07-16 | 上海交联药物研发有限公司 | 一种高表达安丝菌素p-3的方法 |
| DK3956332T3 (da) | 2019-04-18 | 2023-05-01 | Indena Spa | Diasteroselektiv fremgangsmåde til fremstilling af thiol- eller disulfid-holdige maytansionidestere og mellemprodukter deraf |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3795585A (en) * | 1972-08-31 | 1974-03-05 | Agency Ind Science Techn | Method for manufacture of alpha-galactosidase |
| US4151042A (en) * | 1977-03-31 | 1979-04-24 | Takeda Chemical Industries, Ltd. | Method for producing maytansinol and its derivatives |
| US4162940A (en) * | 1977-03-31 | 1979-07-31 | Takeda Chemical Industries, Ltd. | Method for producing Antibiotic C-15003 by culturing nocardia |
| JPS6010720B2 (ja) * | 1977-11-18 | 1985-03-19 | 武田薬品工業株式会社 | 抗生物質c―15003 p―4の製造法 |
| JPS6016236B2 (ja) * | 1977-11-18 | 1985-04-24 | 武田薬品工業株式会社 | 抗生物質c―15003 p―3の製造法 |
-
1979
- 1979-12-28 JP JP17381979A patent/JPS56102793A/ja active Granted
-
1980
- 1980-11-13 EP EP80107008A patent/EP0031430B1/en not_active Expired
- 1980-11-13 DE DE8080107008T patent/DE3066026D1/de not_active Expired
- 1980-11-13 AT AT80107008T patent/ATE5726T1/de not_active IP Right Cessation
- 1980-11-21 ES ES497033A patent/ES497033A0/es active Granted
- 1980-11-24 US US06/209,983 patent/US4356265A/en not_active Expired - Lifetime
- 1980-12-23 HU HU803107A patent/HU182267B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS56102793A (en) | 1981-08-17 |
| ES8107306A1 (es) | 1981-10-01 |
| US4356265A (en) | 1982-10-26 |
| ATE5726T1 (de) | 1984-01-15 |
| EP0031430A3 (en) | 1981-10-07 |
| ES497033A0 (es) | 1981-10-01 |
| EP0031430A2 (en) | 1981-07-08 |
| EP0031430B1 (en) | 1983-12-28 |
| JPS6316120B2 (2) | 1988-04-07 |
| DE3066026D1 (en) | 1984-02-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |