HUE044765T2 - Polimerizálható hosszabbított láncú polisziloxánok hidrofil oldalcsoportokkal - Google Patents

Polimerizálható hosszabbított láncú polisziloxánok hidrofil oldalcsoportokkal

Info

Publication number
HUE044765T2
HUE044765T2 HUE11770626A HUE044765T2 HU E044765 T2 HUE044765 T2 HU E044765T2 HU E11770626 A HUE11770626 A HU E11770626A HU E044765 T2 HUE044765 T2 HU E044765T2
Authority
HU
Hungary
Prior art keywords
hydrophilic groups
pendant hydrophilic
polysiloxanes
extended
polymerisable chain
Prior art date
Application number
Other languages
English (en)
Inventor
Frank Chang
Jinyu Huang
Laura Sanders
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HUE044765T2 publication Critical patent/HUE044765T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C08G77/46—Block-or graft-polymers containing polysiloxane sequences containing polyether sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/068—Polysiloxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/22—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen
    • C08G77/28—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen sulfur-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/48—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule in which at least two but not all the silicon atoms are connected by linkages other than oxygen atoms
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Eyeglasses (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Materials For Medical Uses (AREA)
HUE11770626 2010-10-06 2011-10-05 Polimerizálható hosszabbított láncú polisziloxánok hidrofil oldalcsoportokkal HUE044765T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39044810P 2010-10-06 2010-10-06

Publications (1)

Publication Number Publication Date
HUE044765T2 true HUE044765T2 (hu) 2019-11-28

Family

ID=44802413

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE11770626 HUE044765T2 (hu) 2010-10-06 2011-10-05 Polimerizálható hosszabbított láncú polisziloxánok hidrofil oldalcsoportokkal

Country Status (6)

Country Link
US (2) US8993651B2 (hu)
EP (1) EP2625216B1 (hu)
JP (1) JP5784131B2 (hu)
CA (1) CA2813469C (hu)
HU (1) HUE044765T2 (hu)
WO (1) WO2012047961A1 (hu)

Families Citing this family (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5720103B2 (ja) * 2010-03-18 2015-05-20 東レ株式会社 シリコーンハイドロゲル、眼用レンズおよびコンタクトレンズ
WO2012047964A1 (en) 2010-10-06 2012-04-12 Novartis Ag Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains
US8742154B2 (en) * 2011-11-16 2014-06-03 Momentive Performance Materials Inc. Block ABA silicone polyalkyleneoxicie copolymers, methods of preparation, and applications for employing the same
EP2931733B1 (en) 2012-12-14 2016-10-05 Novartis AG Tris(trimethyl siloxy)silane vinylic monomers and uses thereof
CA2889894C (en) 2012-12-14 2017-09-12 Novartis Ag Actinically-crosslinkable amphiphilic prepolymers
WO2014093764A1 (en) 2012-12-14 2014-06-19 Novartis Ag Amphiphilic siloxane-containing (meth)acrylamides and uses thereof
US9103965B2 (en) 2012-12-14 2015-08-11 Novartis Ag Amphiphilic siloxane-containing vinylic monomers and uses thereof
US20230200976A1 (en) 2013-02-14 2023-06-29 Shifamed Holdings, Llc Accommodating intraocular lens
US9486311B2 (en) 2013-02-14 2016-11-08 Shifamed Holdings, Llc Hydrophilic AIOL with bonding
US10195018B2 (en) 2013-03-21 2019-02-05 Shifamed Holdings, Llc Accommodating intraocular lens
CN105392448B (zh) 2013-03-21 2017-10-20 施菲姆德控股有限责任公司 调节性人工晶状体
US10532125B1 (en) * 2013-06-27 2020-01-14 Vanderbilt University Shape memory polymers and methods of use
CN105579480B (zh) 2013-09-30 2019-02-22 诺华股份有限公司 用于制备吸收uv的眼用透镜的方法
US9568645B2 (en) 2013-09-30 2017-02-14 Novartis Ag Silicone hydrogel lenses with relatively-long thermal stability
HUE040618T2 (hu) 2013-10-31 2019-03-28 Novartis Ag Eljárás szemészeti lencsék elõállítására
MY183117A (en) 2013-12-13 2021-02-15 Alcon Inc Method for making contact lenses
JP6355821B2 (ja) 2014-04-25 2018-07-11 ノバルティス アーゲー カルボシロキサンビニル系モノマー
CA2940207C (en) 2014-04-25 2019-09-10 Novartis Ag Hydrophilized carbosiloxane vinylic monomers
JP6267832B2 (ja) 2014-08-26 2018-01-24 シファメド・ホールディングス・エルエルシー 調節式眼内レンズ
EP3197940B1 (en) * 2014-09-26 2023-02-15 Alcon Inc. Polymerizable polysiloxanes with hydrophilic substituents
MY179854A (en) 2015-05-07 2020-11-18 Alcon Inc Method for producing contact lenses with durable lubricious coatings thereon
US9724649B2 (en) 2015-06-25 2017-08-08 Pall Corporation Self-wetting porous membranes (I)
EP3344447B1 (en) 2015-09-04 2019-12-11 Novartis AG Method for producing contact lenses with durable lubricious coatings thereon
JP6680870B2 (ja) 2015-09-04 2020-04-15 アルコン インク. その上に耐久性潤滑性コーティングを有するソフトシリコーン医療デバイス
EP3376999B1 (en) 2015-11-18 2021-08-04 Shifamed Holdings, LLC Multi-piece accommodating intraocular lens
US11141263B2 (en) 2015-11-18 2021-10-12 Shifamed Holdings, Llc Multi-piece accommodating intraocular lens
MY185317A (en) * 2015-12-15 2021-05-03 Novartis Ag Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof
CA3004158C (en) 2015-12-15 2020-06-30 Novartis Ag Amphiphilic branched polydiorganosiloxane macromers
US10081142B2 (en) 2015-12-15 2018-09-25 Novartis Ag Method for producing contact lenses with a lubricious surface
EP3390497B1 (en) * 2015-12-15 2021-01-20 Alcon Inc. Polymerizable polysiloxanes with hydrophilic substituents
KR101841016B1 (ko) * 2016-02-18 2018-03-22 주식회사 인터로조 실록산 단량체, 이를 포함하는 실리콘하이드로겔 렌즈 제조용 조성물 및 실리콘하이드로겔 렌즈
WO2017145023A1 (en) * 2016-02-22 2017-08-31 Novartis Ag Soft silicone medical devices
US10268053B2 (en) 2016-02-22 2019-04-23 Novartis Ag UV/visible-absorbing vinylic monomers and uses thereof
JP6546352B2 (ja) 2016-02-22 2019-07-17 ノバルティス アーゲー Uv吸収ビニルモノマーおよびその使用
WO2017188333A1 (ja) * 2016-04-28 2017-11-02 住友化学株式会社 化合物、及び化合物を含む組成物
WO2018055491A1 (en) 2016-09-20 2018-03-29 Novartis Ag Process for producing contact lenses with durable lubricious coatings thereon
CA3033596C (en) 2016-10-11 2021-02-09 Novartis Ag Polymerizable polydimethylsiloxane-polyoxyalkylene block copolymers
CA3033595C (en) 2016-10-11 2021-06-29 Novartis Ag Chain-extended polydimethylsiloxane vinylic crosslinkers and uses thereof
JP6954679B2 (ja) 2016-12-23 2021-10-27 シファメド・ホールディングス・エルエルシー マルチピース調節式眼内レンズ、及び同を作成し、使用するための方法
ES2678773B1 (es) * 2017-01-16 2019-06-12 Consejo Superior Investigacion Recubrimientos tipo hidrogel en base vinil-lactamas
CN110996848B (zh) 2017-05-30 2023-08-04 施菲姆德控股有限责任公司 调节性人工晶状体的表面处理以及相关方法和装置
US10875967B2 (en) 2017-06-07 2020-12-29 Alcon Inc. Silicone hydrogel contact lenses
WO2018227014A1 (en) 2017-06-07 2018-12-13 Shifamed Holdings, Llc Adjustable optical power intraocular lenses
JP6831020B2 (ja) 2017-06-07 2021-02-17 アルコン インク. シリコーンヒドロゲルコンタクトレンズ
US10843422B2 (en) 2017-06-07 2020-11-24 Alcon, Inc. Method for producing silicone hydrogel contact lenses
EP3447475B1 (en) 2017-08-24 2020-06-17 Alcon Inc. Method and apparatus for determining a coefficient of friction at a test site on a surface of a contact lens
WO2019043577A1 (en) 2017-08-29 2019-03-07 Novartis Ag CASTING MOLDING PROCESS FOR PRODUCING CONTACT LENSES
MY201826A (en) 2017-12-13 2024-03-19 Alcon Inc Method for producing mps-compatible water gradient contact lenses
WO2019142132A1 (en) 2018-01-22 2019-07-25 Novartis Ag Cast-molding process for producing uv-absorbing contact lenses
EP3743463A1 (en) 2018-01-26 2020-12-02 Bausch & Lomb Incorporated Method for end-capping a polysiloxane prepolymer
WO2019162881A1 (en) 2018-02-26 2019-08-29 Novartis Ag Silicone hydrogel contact lenses
SG11202007012TA (en) 2018-03-28 2020-10-29 Alcon Inc Method for making silicone hydrogel contact lenses
WO2019199713A1 (en) 2018-04-13 2019-10-17 Board Of Trustees Of Michigan State University Methods for forming omniphobic thermoset compositions and related articles
WO2019234593A1 (en) 2018-06-04 2019-12-12 Alcon Inc. Method for producing silicone hydrogel contact lenses
WO2019234591A1 (en) 2018-06-04 2019-12-12 Alcon Inc. Method for producing silicone hydrogel contact lenses
US11433629B2 (en) 2018-06-04 2022-09-06 Alcon Inc. Method for preparing silicone hydrogels
US11061169B2 (en) 2018-11-15 2021-07-13 Alcon Inc. Contact lens with phosphorylcholine-modified polyvinylalcohols therein
CN109254370B (zh) * 2018-11-29 2020-10-02 安徽牡东通讯光缆有限公司 一种防水应急光缆
WO2020115570A1 (en) 2018-12-03 2020-06-11 Alcon Inc. Method for making coated silicone hydrogel contact lenses
HUE062555T2 (hu) 2018-12-03 2023-11-28 Alcon Inc Eljárás bevonatos szilikonhidrogél-kontaktlencsék elõállítására
EP3953744B1 (en) 2019-04-10 2025-08-13 Alcon Inc. Method for producing coated contact lenses
MY204149A (en) 2019-05-13 2024-08-09 Alcon Inc Method for producing photochromic contact lenses
WO2020240440A1 (en) 2019-05-28 2020-12-03 Alcon Inc. Method for making opaque colored silicone hydrogel contact lenses
US11602910B2 (en) 2019-05-28 2023-03-14 Alcon Inc. Pad transfer printing method for making colored contact lenses
US12521232B2 (en) 2019-07-11 2026-01-13 Shifamed Holdings, Llc Accommodating intraocular lenses and associated methods
US12072556B2 (en) 2019-11-04 2024-08-27 Alcon Inc. Contact lenses with surfaces having different softness
ES2993009T3 (en) 2019-12-16 2024-12-20 Alcon Inc Wettable silicone hydrogel contact lenses
US20210284778A1 (en) 2020-03-11 2021-09-16 Alcon Inc. Photochromic polydiorganosiloxane vinylic crosslinkers
WO2021186380A1 (en) 2020-03-19 2021-09-23 Alcon Inc. Method for producing embedded or hybrid hydrogel contact lenses
TWI788804B (zh) 2020-03-19 2023-01-01 瑞士商愛爾康公司 用於嵌入式接觸鏡片之高折射率矽氧烷插入物材料
AU2021236973B2 (en) 2020-03-19 2024-05-09 Alcon Inc. Insert materials with high oxygen permeability and high refractive index
WO2021186383A1 (en) 2020-03-19 2021-09-23 Alcon Inc. Embedded silicone hydrogel contact lenses
US12116442B2 (en) 2020-05-07 2024-10-15 Alcon Inc. Method for producing silicone hydrogel contact lenses
WO2021245551A1 (en) 2020-06-02 2021-12-09 Alcon Inc. Method for making photochromic contact lenses
US12358247B2 (en) 2020-07-28 2025-07-15 Alcon Inc. Contact lenses with softer lens surfaces
EP4237232B1 (en) 2020-10-28 2024-11-27 Alcon Inc. Method for making photochromic contact lenses
HUE070248T2 (hu) 2020-11-04 2025-05-28 Alcon Inc Eljárás fotokróm kontaktlencsék elõállítására
HUE069913T2 (hu) 2020-11-04 2025-04-28 Alcon Inc Eljárás fotokróm kontaktlencsék elõállítására
JP7690041B2 (ja) 2021-02-09 2025-06-09 アルコン インク. 親水化ポリジオルガノシロキサンビニル架橋剤
EP4304842B1 (en) 2021-03-08 2026-05-06 Alcon Inc. Method for making photofunctional contact lenses
EP4314118B1 (en) 2021-03-23 2025-04-30 Alcon Inc. Polysiloxane vinylic crosslinkers with high refractive index
US12194698B2 (en) 2021-03-24 2025-01-14 Alcon Inc. Method for making embedded hydrogel contact lenses
EP4313568B1 (en) 2021-04-01 2025-04-30 Alcon Inc. Embedded hydrogel contact lenses
EP4313569B1 (en) 2021-04-01 2026-03-04 Alcon Inc. Method for making embedded hydrogel contact lenses
US11833771B2 (en) 2021-04-01 2023-12-05 Alcon Inc. Method for making photochromic contact lenses
MX2023015075A (es) 2021-06-14 2024-01-18 Alcon Inc Lentes de contacto multifocales difractivas de hidrogel de silicona.
JP7541419B2 (ja) * 2022-04-22 2024-08-28 エル・コーポレイション アクリレート官能基を有する線状ブロック共重合体強化剤
WO2023209570A1 (en) 2022-04-26 2023-11-02 Alcon Inc. Method for making embedded hydrogel contact lenses
US12358188B2 (en) 2022-04-26 2025-07-15 Alcon Inc. Method for making embedded hydrogel contact lenses
WO2023209631A1 (en) 2022-04-28 2023-11-02 Alcon Inc. Method for making uv and hevl-absorbing ophthalmic lenses
US12638614B2 (en) 2022-04-29 2026-05-26 Alcon Inc. Method for making silicone hydrogel contact lenses
WO2023218324A1 (en) 2022-05-09 2023-11-16 Alcon Inc. Method for making embedded hydrogel contact lenses
EP4529621A1 (en) 2022-05-23 2025-04-02 Alcon Inc. Uv/hevl-filtering contact lenses
TW202406713A (zh) 2022-05-23 2024-02-16 瑞士商愛爾康公司 用於製造hevl過濾性接觸鏡片之方法
KR20240172202A (ko) 2022-05-25 2024-12-09 알콘 인코포레이티드 내장형 히드로겔 콘택트 렌즈의 제조 방법
JP2025525733A (ja) 2022-08-17 2025-08-07 アルコン インク. ハイドロゲルコーティングをその上に有するコンタクトレンズ
TWI828345B (zh) * 2022-09-30 2024-01-01 晶碩光學股份有限公司 矽氧烷單體、隱形眼鏡組成物及隱形眼鏡
WO2024161344A1 (en) 2023-02-02 2024-08-08 Alcon Inc. Water gradient silicone hydrogel contact lenses
TW202441215A (zh) 2023-02-27 2024-10-16 瑞士商愛爾康公司 用於生產可潤濕矽酮水凝膠接觸鏡片之方法
TW202500366A (zh) 2023-03-22 2025-01-01 瑞士商愛爾康公司 用於製造嵌入式水凝膠接觸鏡片之方法
EP4713721A1 (en) 2023-05-18 2026-03-25 Alcon Inc. Uv/hevl-filtering silicone hydrogel contact lenses
WO2024236526A2 (en) 2023-05-18 2024-11-21 Alcon Inc. High-energy-violet-absorbing vinylic monomers
WO2024241239A1 (en) 2023-05-25 2024-11-28 Alcon Inc. Coated silicone hydrogel contact lenses and method for making the same
TW202513285A (zh) 2023-06-01 2025-04-01 瑞士商愛爾康公司 用於製造嵌入式水凝膠接觸鏡片之方法
EP4758195A2 (en) 2023-08-07 2026-06-17 Alcon Inc. Uv/hevl-filtering silicone hydrogel contact lenses
CN117363212B (zh) * 2023-11-01 2024-05-17 常熟理工学院 一种基于亲和协同效果的有机硅海洋防污涂料
US20250164823A1 (en) 2023-11-20 2025-05-22 Alcon Inc. Embedded contact lens with a high refractive index insert therein
WO2025243221A1 (en) 2024-05-22 2025-11-27 Alcon Inc. Reactive hevl-absorbing dyes
US20250362530A1 (en) 2024-05-22 2025-11-27 Alcon Inc. Method for making centrally colored contact lenses
US20250361401A1 (en) 2024-05-22 2025-11-27 Alcon Inc. Reactive dyes
WO2026083258A1 (en) 2024-10-15 2026-04-23 Alcon Inc. Composite contact lenses with ultrathin objects
US20260118700A1 (en) 2024-10-29 2026-04-30 Alcon Inc. Diffractive multifocal contact lens
US20260132236A1 (en) 2024-11-11 2026-05-14 Alcon Inc. Light absorbers for ophthalmc lens materals and devices
WO2026105013A1 (en) 2024-11-14 2026-05-21 Alcon Inc. Contact lenses with color filtering zone
WO2026139849A1 (en) 2024-12-23 2026-07-02 Alcon Inc. Embedded diffractive contact lenses
CN119823383B (zh) * 2025-01-09 2025-12-05 安徽大学 一种两亲性聚合物及其制备方法和应用
US20260219423A1 (en) 2025-01-29 2026-07-30 Alcon Inc. Controlled release of dry eye relief agent from contact lens

Family Cites Families (212)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042552A (en) 1972-09-19 1977-08-16 Warner-Lambert Company Composition for hydrophilic lens blank and method of casting
US4045547A (en) 1974-11-21 1977-08-30 Warner-Lambert Company Fabrication of soft contact lens and composition therefor
US4245069A (en) 1978-12-28 1981-01-13 Permavision Polysiloxane composition
US4182822A (en) 1976-11-08 1980-01-08 Chang Sing Hsiung Hydrophilic, soft and oxygen permeable copolymer composition
US4343927A (en) 1976-11-08 1982-08-10 Chang Sing Hsiung Hydrophilic, soft and oxygen permeable copolymer compositions
US4136250A (en) * 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4153641A (en) 1977-07-25 1979-05-08 Bausch & Lomb Incorporated Polysiloxane composition and contact lens
US4189546A (en) 1977-07-25 1980-02-19 Bausch & Lomb Incorporated Polysiloxane shaped article for use in biomedical applications
US4261875A (en) 1979-01-31 1981-04-14 American Optical Corporation Contact lenses containing hydrophilic silicone polymers
US4254248A (en) 1979-09-13 1981-03-03 Bausch & Lomb Incorporated Contact lens made from polymers of polysiloxane and polycyclic esters of acrylic acid or methacrylic acid
US4276402A (en) 1979-09-13 1981-06-30 Bausch & Lomb Incorporated Polysiloxane/acrylic acid/polcyclic esters of methacrylic acid polymer contact lens
US4312575A (en) 1979-09-18 1982-01-26 Peyman Gholam A Soft corneal contact lens with tightly cross-linked polymer coating and method of making same
US4260725A (en) 1979-12-10 1981-04-07 Bausch & Lomb Incorporated Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains
US4259467A (en) 1979-12-10 1981-03-31 Bausch & Lomb Incorporated Hydrophilic contact lens made from polysiloxanes containing hydrophilic sidechains
JPS5770895A (en) * 1980-10-21 1982-05-01 Shin Etsu Chem Co Ltd Silicon-modified polysulfide compound
US4355147A (en) 1981-02-26 1982-10-19 Bausch & Lomb Incorporated Polysiloxane with polycyclic modifier composition and biomedical devices
US4327203A (en) 1981-02-26 1982-04-27 Bausch & Lomb Incorporated Polysiloxane with cycloalkyl modifier composition and biomedical devices
US4341889A (en) 1981-02-26 1982-07-27 Bausch & Lomb Incorporated Polysiloxane composition and biomedical devices
FR2511822A1 (fr) 1981-08-21 1983-02-25 Thomson Csf Circuit logique bistable utilisant des transistors a effet de champ a faible tension de seuil et dispositif de memorisation comportant un tel circuit
US4444711A (en) 1981-12-21 1984-04-24 Husky Injection Molding Systems Ltd. Method of operating a two-shot injection-molding machine
US4661575A (en) 1982-01-25 1987-04-28 Hercules Incorporated Dicyclopentadiene polymer product
US4467082A (en) 1982-03-15 1984-08-21 Dow Corning Corporation Organopolysiloxane photosensitizers and methods for their preparation
US4460534A (en) 1982-09-07 1984-07-17 International Business Machines Corporation Two-shot injection molding
US4485236A (en) 1982-09-27 1984-11-27 Minnesota Mining And Manufacturing Company Azlactone-functional compounds
US4486577A (en) 1982-10-12 1984-12-04 Ciba-Geigy Corporation Strong, silicone containing polymers with high oxygen permeability
US4543398A (en) 1983-04-28 1985-09-24 Minnesota Mining And Manufacturing Company Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols
JPS60163901A (ja) 1984-02-04 1985-08-26 Japan Synthetic Rubber Co Ltd プラズマ重合処理方法
US4605712A (en) 1984-09-24 1986-08-12 Ciba-Geigy Corporation Unsaturated polysiloxanes and polymers thereof
US4833218A (en) 1984-12-18 1989-05-23 Dow Corning Corporation Hydrophilic silicone-organic copolymer elastomers containing bioactine agent
US4666953A (en) 1985-03-28 1987-05-19 Loctite Corporation Silicone polyphotoinitiators
US4711943A (en) 1985-04-26 1987-12-08 Sola U.S.A. Inc. Hydrophilic siloxane monomers and dimers for contact lens materials, and contact lenses fabricated therefrom
EP0216074B1 (en) 1985-07-31 1993-06-16 Ciba-Geigy Ag Polyvinyl alcohol derivatives and crosslinked hydrogel contact lenses made therefrom
IE60271B1 (en) 1986-01-07 1994-06-29 Loctite Ireland Ltd "Thiol/ene compositions"
US4684538A (en) 1986-02-21 1987-08-04 Loctite Corporation Polysiloxane urethane compounds and adhesive compositions, and method of making and using the same
DE3708308A1 (de) 1986-04-10 1987-10-22 Bayer Ag Kontaktoptische gegenstaende
JPS6310632A (ja) * 1986-06-30 1988-01-18 Shin Etsu Chem Co Ltd シリコ−ン組成物
DE3710343A1 (de) 1987-03-28 1988-10-06 Basf Lacke & Farben Verzweigtes acrylatcopolymerisat mit polisierbaren doppelbindungen und verfahren zur herstellung des acrylatcopolymerisats
US4837289A (en) 1987-04-30 1989-06-06 Ciba-Geigy Corporation UV- and heat curable terminal polyvinyl functional macromers and polymers thereof
US4859780A (en) 1988-02-26 1989-08-22 Ciba-Geigy Corporation Hydrophilic modifier monomers
US5070170A (en) 1988-02-26 1991-12-03 Ciba-Geigy Corporation Wettable, rigid gas permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof
US4954587A (en) 1988-07-05 1990-09-04 Ciba-Geigy Corporation Dimethylacrylamide-copolymer hydrogels with high oxygen permeability
JPH0651795B2 (ja) 1988-09-16 1994-07-06 信越化学工業株式会社 メタクリル官能性ジメチルポリシロキサン
US4983702A (en) 1988-09-28 1991-01-08 Ciba-Geigy Corporation Crosslinked siloxane-urethane polymer contact lens
US4954586A (en) 1989-01-17 1990-09-04 Menicon Co., Ltd Soft ocular lens material
AU637361B2 (en) 1989-04-24 1993-05-27 Novartis Ag Polysiloxane-polyoxyalkylene block copolymers and ophthalmic devices containing them
US5070215A (en) 1989-05-02 1991-12-03 Bausch & Lomb Incorporated Novel vinyl carbonate and vinyl carbamate contact lens material monomers
US5034461A (en) 1989-06-07 1991-07-23 Bausch & Lomb Incorporated Novel prepolymers useful in biomedical devices
DE3927667A1 (de) 1989-08-22 1991-02-28 Espe Stiftung Verwendung von photopolymerisierbaren massen als introkularlinsen-fuellmaterial bei der bekaempfung von katarakt und anderen augenkrankheiten
US5079319A (en) 1989-10-25 1992-01-07 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
US5010141A (en) 1989-10-25 1991-04-23 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
US5314960A (en) 1990-04-10 1994-05-24 Permeable Technologies, Inc. Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment
US5244981A (en) 1990-04-10 1993-09-14 Permeable Technologies, Inc. Silicone-containing contact lens polymers, oxygen permeable contact lenses and methods for making these lenses and treating patients with visual impairment
DE69101464T2 (de) 1990-04-26 1994-07-14 Ciba Geigy Ungesättigte Harnstoff-Polysiloxane.
US5314961A (en) 1990-10-11 1994-05-24 Permeable Technologies, Inc. Silicone-containing polymers, compositions and improved oxygen permeable hydrophilic contact lenses
US5219965A (en) 1990-11-27 1993-06-15 Bausch & Lomb Incorporated Surface modification of polymer objects
US5158717A (en) 1990-11-27 1992-10-27 Bausch & Lomb Incorporated Method of molding shaped polymeric articles
US5194556A (en) 1991-01-09 1993-03-16 Ciba-Geigy Corporation Rigid contact lenses with improved oxygen permeability
US5559163A (en) 1991-01-28 1996-09-24 The Sherwin-Williams Company UV curable coatings having improved weatherability
AU647880B2 (en) 1991-02-28 1994-03-31 Ciba-Geigy Ag Contact lenses made from thermoformable material
CA2108682A1 (en) 1991-04-18 1992-10-19 Richard Y. S. Chen Novel composition for contact lenses
JPH05238950A (ja) 1991-04-22 1993-09-17 Sanwa Kagaku Kenkyusho Co Ltd 易吸収性vip製剤
US5164462A (en) 1991-04-25 1992-11-17 Allergan, Inc. Ultraviolet light absorbing compounds and silicone compositions
US5352753A (en) 1991-04-25 1994-10-04 Allergan, Inc. Ultraviolet light absorbing compounds, silicone compositions and methods for making same
EP0603268B1 (en) 1991-09-12 1996-12-18 BAUSCH & LOMB INCORPORATED Wettable silicone hydrogel compositions and methods
DE69211152T2 (de) 1991-11-05 1997-01-02 Bausch & Lomb Zusammensetzungen von benetzbaren siliconhydrogels und verfahren zu deren herstellung
US5310779A (en) 1991-11-05 1994-05-10 Bausch & Lomb Incorporated UV curable crosslinking agents useful in copolymerization
JP3270100B2 (ja) * 1992-02-27 2002-04-02 三菱化学株式会社 高屈折率光学材料
JPH05310837A (ja) 1992-05-14 1993-11-22 Japan Synthetic Rubber Co Ltd 酸素透過性高分子材料の製造方法
US5358995A (en) 1992-05-15 1994-10-25 Bausch & Lomb Incorporated Surface wettable silicone hydrogels
JP3195662B2 (ja) 1992-08-24 2001-08-06 株式会社メニコン 眼用レンズ材料
JP2774233B2 (ja) 1992-08-26 1998-07-09 株式会社メニコン 眼用レンズ材料
KR100209818B1 (ko) 1992-09-04 1999-07-15 사또 아끼오 분해성점착필름 및 분해성수지조성물
BR9406280A (pt) 1993-04-22 1996-02-06 Jessen Wesley Corp Benzotriazois absorventes de UV tendo um group estireno
TW328535B (en) 1993-07-02 1998-03-21 Novartis Ag Functional photoinitiators and their manufacture
US6800225B1 (en) 1994-07-14 2004-10-05 Novartis Ag Process and device for the manufacture of mouldings and mouldings manufactured in accordance with that process
TW272976B (hu) 1993-08-06 1996-03-21 Ciba Geigy Ag
GB9321714D0 (en) 1993-10-21 1993-12-15 Sandoz Ltd Improvements in or relating to organic compounds
US5712356A (en) 1993-11-26 1998-01-27 Ciba Vision Corporation Cross-linkable copolymers and hydrogels
US5894002A (en) 1993-12-13 1999-04-13 Ciba Vision Corporation Process and apparatus for the manufacture of a contact lens
TW303379B (hu) 1994-03-02 1997-04-21 Ciba Sc Holding Ag
US5480927A (en) 1994-05-20 1996-01-02 Ciba Geigy Corporation Method of increasing the concentration of radiation-absorbing agents in optical and ophthalmic lenses
US5843346A (en) 1994-06-30 1998-12-01 Polymer Technology Corporation Method of cast molding contact lenses
TW381106B (en) 1994-09-02 2000-02-01 Ciba Sc Holding Ag Alkoxyphenyl-substituted bisacylphosphine oxides
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US6342570B1 (en) 1994-11-14 2002-01-29 Novartis Ag Cross-linkable copolymers and hydrogels
US5665840A (en) 1994-11-18 1997-09-09 Novartis Corporation Polymeric networks from water-soluble prepolymers
TW434456B (en) 1994-12-30 2001-05-16 Novartis Ag A compound as functionalized photoinitiator, its production process, its corresponding oligomers or polymers and its application in coating a substrate
TW349967B (en) 1995-02-03 1999-01-11 Novartis Ag Process for producing contact lenses and a cross-linkable polyvinylalcohol used therefor
US5849841A (en) 1995-02-03 1998-12-15 Ciba Vision Corporation Crosslinked polymers containing ester or amide groups
GB9504996D0 (en) 1995-03-11 1995-04-26 Zeneca Ltd Compositions
TW393498B (en) 1995-04-04 2000-06-11 Novartis Ag The preparation and use of Polysiloxane-comprising perfluoroalkyl ethers
DE29624309U1 (de) 1995-04-04 2002-01-03 Commonwealth Scientific And Industrial Research Organisation, Campbell Dauertraglinsen
US5681871A (en) 1995-05-24 1997-10-28 Johnson & Johnson Vision Products, Inc. Method for preparing ultraviolet radiation absorbing contact lenses
AUPN354595A0 (en) 1995-06-14 1995-07-06 Ciba-Geigy Ag Novel materials
SE520727C2 (sv) 1996-03-04 2003-08-19 Ciba Sc Holding Ag Alkylfenylbisacylfosfinoxid och fotoinitiatorblandningar
US6361925B1 (en) 1996-03-04 2002-03-26 Ciba Specialty Chemicals Corporation Photoinitiator mixtures and compositions with alkylphenylbisacylphosphine oxides
AR008108A1 (es) 1996-08-01 1999-12-09 Novartis Ag Un metodo para formar un articulo polimerico absorbente de radiacion, un articulo polimerico asi formado, y un metodo para formar un tintepolimerico
AU727078B2 (en) 1996-10-21 2000-11-30 Biocure, Inc. Crosslinkable polymers
TW369617B (en) * 1996-12-06 1999-09-11 Toray Industries Plastic articles for medical use
AU7533696A (en) 1996-12-13 1998-06-18 Ciba-Geigy Ag New materials
TW425403B (en) 1997-02-04 2001-03-11 Novartis Ag Branched polyurethane (meth)acrylate prepolymers, opthal-mic mouldings derived therefrom and processes for their manufacture
EP0867456A1 (de) 1997-02-04 1998-09-30 Novartis AG Ophthalmischer Formkörper
WO1998037441A1 (en) 1997-02-21 1998-08-27 Novartis Ag Ophthalmic mouldings
AU7084798A (en) 1997-04-22 1998-11-13 Dsm N.V. Liquid curable resin composition
US6359025B1 (en) 1997-05-16 2002-03-19 Dsm N.V. Radiation-curable liquid resin composition for coating optical fibers
US5989462A (en) 1997-07-31 1999-11-23 Q2100, Inc. Method and composition for producing ultraviolent blocking lenses
US6015842A (en) 1997-08-07 2000-01-18 Alcon Laboratories, Inc. Method of preparing foldable hydrophilic ophthalmic device materials
JP3722986B2 (ja) 1997-08-29 2005-11-30 株式会社ニデック 紫外線吸収性基材
JP4616473B2 (ja) 1997-09-16 2011-01-19 ノバルティス アーゲー 架橋結合可能なポリ尿素ポリマー類
US6020445A (en) 1997-10-09 2000-02-01 Johnson & Johnson Vision Products, Inc. Silicone hydrogel polymers
TW429327B (en) 1997-10-21 2001-04-11 Novartis Ag Single mould alignment
JPH11130744A (ja) 1997-10-29 1999-05-18 Menicon Co Ltd 架橋性化合物およびそれを用いてなる光学材料
US5981669A (en) 1997-12-29 1999-11-09 Bausch & Lomb Incorporated Silicone-containing prepolymers and low water materials
US6451871B1 (en) 1998-11-25 2002-09-17 Novartis Ag Methods of modifying surface characteristics
JP4125426B2 (ja) 1998-02-06 2008-07-30 三井化学ポリウレタン株式会社 低反発性ウレタンフォーム
US20070043140A1 (en) 1998-03-02 2007-02-22 Lorenz Kathrine O Method for the mitigation of symptoms of contact lens related dry eye
US5962548A (en) 1998-03-02 1999-10-05 Johnson & Johnson Vision Products, Inc. Silicone hydrogel polymers
US6367929B1 (en) 1998-03-02 2002-04-09 Johnson & Johnson Vision Care, Inc. Hydrogel with internal wetting agent
US7461937B2 (en) 2001-09-10 2008-12-09 Johnson & Johnson Vision Care, Inc. Soft contact lenses displaying superior on-eye comfort
US6849671B2 (en) 1998-03-02 2005-02-01 Johnson & Johnson Vision Care, Inc. Contact lenses
US6822016B2 (en) 2001-09-10 2004-11-23 Johnson & Johnson Vision Care, Inc. Biomedical devices containing internal wetting agents
US7052131B2 (en) 2001-09-10 2006-05-30 J&J Vision Care, Inc. Biomedical devices containing internal wetting agents
US6943203B2 (en) 1998-03-02 2005-09-13 Johnson & Johnson Vision Care, Inc. Soft contact lenses
US5998498A (en) 1998-03-02 1999-12-07 Johnson & Johnson Vision Products, Inc. Soft contact lenses
US6218463B1 (en) 1998-04-20 2001-04-17 Johnson & Johnson Vision Care, Inc. Ocular devices manufactured with free radical-polymerizable latent ultra-violet absorbers
US6036891A (en) 1998-05-11 2000-03-14 Pharmacia & Upjohn Polymerizable hydrophilic ultraviolet light absorbing monomers
US6359024B2 (en) 1998-05-15 2002-03-19 Bausch & Lomb Incorporated Method for polymerizing contact lenses
US5914355A (en) 1998-05-15 1999-06-22 Bausch & Lomb Incorporated Method for making contact lenses having UV absorbing properties
US5989117A (en) 1998-07-01 1999-11-23 Lin; Kuei-Chou Shellfish wash device
AU4980199A (en) 1998-07-08 2000-02-01 Sunsoft Corporation Interpenetrating polymer network hydrophilic hydrogels for contact lens
US5959117A (en) 1998-08-10 1999-09-28 Bausch & Lomb Monomers useful for contact lens materials
US6149692A (en) 1998-08-27 2000-11-21 Novartis Ag Method and composition for incorporating radiation-absorbing agents into polymers
US6039913A (en) 1998-08-27 2000-03-21 Novartis Ag Process for the manufacture of an ophthalmic molding
US6241766B1 (en) 1998-10-29 2001-06-05 Allergan Sales, Inc. Intraocular lenses made from polymeric compositions
EP1002807A1 (en) 1998-11-20 2000-05-24 Novartis AG Functionalized resin derived from polyallylamine
US5981675A (en) 1998-12-07 1999-11-09 Bausch & Lomb Incorporated Silicone-containing macromonomers and low water materials
US6329485B1 (en) 1998-12-11 2001-12-11 Bausch & Lomb Incorporated High refractive index hydrogel compositions for ophthalmic implants
US6422794B1 (en) 1998-12-16 2002-07-23 Holland Company Cargo snugger strap and hook mechanism
AU4112400A (en) 1999-03-30 2000-10-23 Novartis Ag Organic compounds
JP3449406B2 (ja) 1999-04-07 2003-09-22 Hoyaヘルスケア株式会社 新規ピラゾロン化合物およびそれを用いた眼用プラスチックレンズ
US6252032B1 (en) 1999-07-07 2001-06-26 Minimed Inc. UV absorbing polymer
DE60004854T2 (de) 1999-07-27 2004-06-09 Bausch & Lomb Inc. Kontaktlinsenmaterial
US6376568B1 (en) 1999-07-29 2002-04-23 Ciba Specialty Chemicals Corporation Surface-active photoinitiators
EP1754728B1 (en) 1999-10-07 2010-02-24 Johson & Johnson Vision Care Inc. Soft contact lenses
US6719929B2 (en) 2000-02-04 2004-04-13 Novartis Ag Method for modifying a surface
US6793973B2 (en) 2000-02-04 2004-09-21 Novartis Ag Single-dip process for achieving a layer-by-layer-like coating
US7521519B1 (en) 2000-03-14 2009-04-21 Novartis Ag Organic compounds
JP3850729B2 (ja) 2000-03-22 2006-11-29 株式会社メニコン 眼用レンズ材料
ES2222373T3 (es) 2000-03-24 2005-02-01 Novartis Ag Prepolimeros reticulares o polimerizables.
US6881269B2 (en) 2000-08-17 2005-04-19 Novartis Ag Lens plasma coating system
US6852353B2 (en) 2000-08-24 2005-02-08 Novartis Ag Process for surface modifying substrates and modified substrates resulting therefrom
US20040115242A1 (en) 2001-12-20 2004-06-17 Meyers Ann-Marie W. Antimicrobial contact lenses and methods for their production
US20050260249A1 (en) 2000-12-21 2005-11-24 Neely Frank L Antimicrobial contact lenses and methods for their production
US20040213827A1 (en) 2000-12-21 2004-10-28 Enns John B. Antimicrobial contact lenses and methods for their production
US20040151755A1 (en) 2000-12-21 2004-08-05 Osman Rathore Antimicrobial lenses displaying extended efficacy, processes to prepare them and methods of their use
US20030044447A1 (en) 2000-12-21 2003-03-06 Diana Zanini Antimicrobial contact lenses and methods for their production
ATE433455T1 (de) 2001-03-30 2009-06-15 Johnson & Johnson Vision Care Monomer, polymer und jeweils daraus erhaltene okularlinse und kontaktlinse
WO2002081532A1 (en) 2001-03-30 2002-10-17 Johnson & Johnson Vision Care, Inc. Monomers, polymers, and ophthalmic lenses and contact lenses made by using the same
JP2003066381A (ja) 2001-05-23 2003-03-05 Novartis Ag 流体で物品を処理するためのシステム及び方法
US6811805B2 (en) 2001-05-30 2004-11-02 Novatis Ag Method for applying a coating
US6811804B2 (en) 2001-06-07 2004-11-02 Abbott Laboratories Juice and soy protein beverage and uses thereof
US6776934B2 (en) 2001-11-02 2004-08-17 Bausch & Lomb Incorporated Method for polymerizing lenses
TWI255224B (en) 2002-01-09 2006-05-21 Novartis Ag Polymeric articles having a lubricious coating and method for making the same
US6846892B2 (en) 2002-03-11 2005-01-25 Johnson & Johnson Vision Care, Inc. Low polydispersity poly-HEMA compositions
US6852793B2 (en) 2002-06-19 2005-02-08 Bausch & Lomb Incorporated Low water content, high refractive index, flexible, polymeric compositions
EP1534767B1 (en) 2002-08-14 2007-11-28 Novartis AG Radiation-curable prepolymers
US20070138692A1 (en) 2002-09-06 2007-06-21 Ford James D Process for forming clear, wettable silicone hydrogel articles
US20040150788A1 (en) 2002-11-22 2004-08-05 Ann-Margret Andersson Antimicrobial lenses, processes to prepare them and methods of their use
US20080299179A1 (en) 2002-09-06 2008-12-04 Osman Rathore Solutions for ophthalmic lenses containing at least one silicone containing component
US6896926B2 (en) 2002-09-11 2005-05-24 Novartis Ag Method for applying an LbL coating onto a medical device
US6926965B2 (en) 2002-09-11 2005-08-09 Novartis Ag LbL-coated medical device and method for making the same
US7387759B2 (en) 2002-12-17 2008-06-17 Novartis Ag System and method for curing polymeric moldings having a masking collar
US7384590B2 (en) 2002-12-17 2008-06-10 Novartis Ag System and method for curing polymeric moldings
EP1477511A1 (en) 2003-05-15 2004-11-17 DSM IP Assets B.V. Radiation curable thiol-ene composition
US7276544B2 (en) 2003-09-08 2007-10-02 Bausch & Lomb Incorporated Process for manufacturing intraocular lenses with blue light absorption characteristics
US7416737B2 (en) 2003-11-18 2008-08-26 Johnson & Johnson Vision Care, Inc. Antimicrobial lenses, processes to prepare them and methods of their use
US7977430B2 (en) 2003-11-25 2011-07-12 Novartis Ag Crosslinkable polyurea prepolymers
US7214809B2 (en) 2004-02-11 2007-05-08 Johnson & Johnson Vision Care, Inc. (Meth)acrylamide monomers containing hydroxy and silicone functionalities
EP1756625B1 (en) 2004-04-21 2014-06-04 Novartis AG Curable colored inks for making colored silicone hydrogel lenses
US20060069178A1 (en) 2004-09-24 2006-03-30 Bausch & Lomb Incorporated Method for polymerizing ophthalmic devices
US7249848B2 (en) 2004-09-30 2007-07-31 Johnson & Johnson Vision Care, Inc. Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents
US7247692B2 (en) 2004-09-30 2007-07-24 Johnson & Johnson Vision Care, Inc. Biomedical devices containing amphiphilic block copolymers
CN100569804C (zh) 2004-11-18 2009-12-16 禾逊专业化学公司 超薄硫醇-烯涂层
US20060252850A1 (en) 2005-05-04 2006-11-09 Bausch & Lomb Incorporated Radiation-absorbing polymeric materials and ophthalmic devices comprising same
US20070092830A1 (en) 2005-10-24 2007-04-26 Bausch & Lomb Incorporated Polymeric radiation-absorbing materials and ophthalmic devices comprising same
US20070092831A1 (en) 2005-10-24 2007-04-26 Bausch & Lomb Incorporated Radiation-absorbing polymeric materials and ophthalmic devices comprising same
US7423108B2 (en) 2005-12-16 2008-09-09 Bausch & Lomb Incorporated High refractive-index siloxy-containing monomers and polymers, and ophthalmic devices comprising such polymers
US7759408B2 (en) 2005-12-21 2010-07-20 Bausch & Lomb Incorporated Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
US8828420B2 (en) 2006-01-06 2014-09-09 Bausch & Lomb Incorporated Siloxane prepolymer containing pendant cationic and polymerizable groups
US7528208B2 (en) 2006-01-06 2009-05-05 Bausch & Lomb Incorporated Siloxane prepolymer containing pendant and end-capping cationic and polymerizable groups
US7825273B2 (en) 2006-01-06 2010-11-02 Bausch & Lomb Incorporated Process for making cationic hydrophilic siloxanyl monomers
US7960447B2 (en) 2006-04-13 2011-06-14 Bausch & Lomb Incorporated Cationic end-capped siloxane prepolymer for reduced cross-link density
CA2651706A1 (en) 2006-05-03 2007-11-15 Vision Crc Limited Biological polysiloxanes
US7858000B2 (en) 2006-06-08 2010-12-28 Novartis Ag Method of making silicone hydrogel contact lenses
US7572841B2 (en) 2006-06-15 2009-08-11 Coopervision International Holding Company, Lp Wettable silicone hydrogel contact lenses and related compositions and methods
US8231218B2 (en) 2006-06-15 2012-07-31 Coopervision International Holding Company, Lp Wettable silicone hydrogel contact lenses and related compositions and methods
US7601766B2 (en) 2006-06-30 2009-10-13 Bausch & Lomb Incorporated Carboxylic siloxanyl monomers with pendant polymerizable groups
US20080004413A1 (en) 2006-06-30 2008-01-03 Derek Schorzman Carboxylic M2Dx-like siloxanyl monomers
US7557231B2 (en) 2006-06-30 2009-07-07 Bausch & Lomb Incorporated Carboxylic tris-like siloxanyl monomers
US7468397B2 (en) 2006-06-30 2008-12-23 Bausch & Lomb Incorporated Polymerizable siloxane-quaternary amine copolymers
ES2346812T3 (es) 2006-07-12 2010-10-20 Novartis Ag Copolimeros actinicamente entrelazables para la fabricacion de lentes de contacto.
US20080076897A1 (en) 2006-09-27 2008-03-27 Kunzler Jay F Pendant end-capped low modulus cationic siloxanyls
AR064286A1 (es) 2006-12-13 2009-03-25 Quiceno Gomez Alexandra Lorena Produccion de dispositivos oftalmicos basados en la polimerizacion por crecimiento escalonado fotoinducida
JP5669396B2 (ja) 2006-12-13 2015-02-12 ノバルティス アーゲー 化学線硬化性シリコーンヒドロゲルコポリマーおよびその使用
MX2009010109A (es) 2007-03-22 2009-10-12 Novartis Ag Prepolimeros que contienen silicona con cadenas polimericas hidrofilicas.
EP2129513B1 (en) 2007-03-22 2016-08-03 Novartis AG Prepolymers with dangling polysiloxane-containing polymer chains
JP2008260887A (ja) * 2007-04-13 2008-10-30 Yokohama Rubber Co Ltd:The 熱可塑性エラストマーおよび熱可塑性エラストマー組成物
US8080622B2 (en) 2007-06-29 2011-12-20 Johnson & Johnson Vision Care, Inc. Soluble silicone prepolymers
BRPI0906434B1 (pt) * 2008-02-08 2019-11-19 Asahi Kasei Aime Co Ltd macromonômero de polissiloxano hidrofílico purificado, método de produzir o mesmo, homopolímero, material de lente oftálmica, lente oftálmica e lente de contato
EP2262631B1 (en) 2008-03-12 2011-07-20 Novartis AG Method and mold for cast molding contact lenses
AU2009333223B2 (en) 2008-12-30 2012-02-23 Novartis Ag Tri-functional UV-absorbing compounds and use thereof
JP2010168452A (ja) * 2009-01-22 2010-08-05 Nippon Steel Chem Co Ltd ポリエン/ポリチオール系感光性樹脂組成物

Also Published As

Publication number Publication date
JP5784131B2 (ja) 2015-09-24
US9109091B2 (en) 2015-08-18
EP2625216A1 (en) 2013-08-14
WO2012047961A1 (en) 2012-04-12
US20120088843A1 (en) 2012-04-12
CA2813469C (en) 2016-01-12
US8993651B2 (en) 2015-03-31
JP2013540187A (ja) 2013-10-31
EP2625216B1 (en) 2019-06-05
CA2813469A1 (en) 2012-04-12
US20150152228A1 (en) 2015-06-04

Similar Documents

Publication Publication Date Title
IL221511A (en) Arilatriazolones associated with bis aryl and their use
ZA201208976B (en) Diversion-resistant microgranules and microtablets
ZA201208173B (en) Peptices and their use
LT2580240T (lt) S100a4 antikūnai ir jų terapinis panaudojimas
WO2012149254A3 (en) Mfg-e8 and uses thereof
EP2894222B8 (en) Human abzyme
EP2617746A4 (en) NEW COPOLYMER
PL2605757T3 (pl) Preparaty oparte na nalbufinie i ich zastosowania
EP2589614A4 (en) NEW COPOLYMER
WO2012023055A9 (en) Pyramid game
EP2579826A4 (en) CONDOM
PL2552440T3 (pl) Nowa kombinacja i zastosowanie
PT2563806E (pt) Leucolectinas humanas e suas utilizações
PL2582733T3 (pl) Polimery z bocznymi grupami sacharydowymi i ich zastosowanie
GB201005382D0 (en) Copolymer
EP2638160B8 (en) Nuclions and ribocapsids
AU2010903481A0 (en) Antigravity Whole Body Exercisers
GB201017628D0 (en) Polymer and light-emitting device
TWM390133U (en) Artificial hand with rotational function
AU2010904801A0 (en) Seleno-Compounds and Therapeutic Uses Thereof
HK1175998A (en) Peptides and their use
GB201008528D0 (en) An orientation surface and uses thereof
GB201015298D0 (en) Eye dab
GB201019361D0 (en) Biosensor and uses thereof
GB201007221D0 (en) siRNA's and use thereof