HUP0004338A2 - Raumatoid artritiszben szenvedő betegek széruma által felismert, citrullint tartalmazó szintetikus peptidek diagnosztikai és terápiás alkalmazásai - Google Patents

Raumatoid artritiszben szenvedő betegek széruma által felismert, citrullint tartalmazó szintetikus peptidek diagnosztikai és terápiás alkalmazásai Download PDF

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Publication number
HUP0004338A2
HUP0004338A2 HU0004338A HUP0004338A HUP0004338A2 HU P0004338 A2 HUP0004338 A2 HU P0004338A2 HU 0004338 A HU0004338 A HU 0004338A HU P0004338 A HUP0004338 A HU P0004338A HU P0004338 A2 HUP0004338 A2 HU P0004338A2
Authority
HU
Hungary
Prior art keywords
ser
gly
peptide
gin
arg
Prior art date
Application number
HU0004338A
Other languages
English (en)
Hungarian (hu)
Inventor
Lydie Meheus
Joseph Raymackers
Ann Union
Original Assignee
Innogenetics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP98870078A external-priority patent/EP0949270A1/fr
Application filed by Innogenetics N.V. filed Critical Innogenetics N.V.
Publication of HUP0004338A2 publication Critical patent/HUP0004338A2/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HU0004338A 1997-11-28 1998-11-30 Raumatoid artritiszben szenvedő betegek széruma által felismert, citrullint tartalmazó szintetikus peptidek diagnosztikai és terápiás alkalmazásai HUP0004338A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97870195 1997-11-28
EP98870078A EP0949270A1 (fr) 1998-04-09 1998-04-09 Peptides synthétiques contenant de la citrulline et reconnus par les sérums de patients souffrant d'arthrite rhumatoide utilisés comme outils de diagnostic et de traitement

Publications (1)

Publication Number Publication Date
HUP0004338A2 true HUP0004338A2 (hu) 2001-02-28

Family

ID=26148315

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004338A HUP0004338A2 (hu) 1997-11-28 1998-11-30 Raumatoid artritiszben szenvedő betegek széruma által felismert, citrullint tartalmazó szintetikus peptidek diagnosztikai és terápiás alkalmazásai

Country Status (8)

Country Link
EP (1) EP1034186A2 (fr)
JP (1) JP2002512939A (fr)
AU (1) AU2155899A (fr)
CA (1) CA2309534A1 (fr)
CZ (1) CZ20001963A3 (fr)
HU (1) HUP0004338A2 (fr)
PL (1) PL344534A1 (fr)
WO (1) WO1999028344A2 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7184426B2 (en) 2002-12-12 2007-02-27 Qualcomm, Incorporated Method and apparatus for burst pilot for a time division multiplex system
FR2773078B1 (fr) * 1997-12-30 2000-05-26 Univ Toulouse Utilisation de peptides citrullines derives de la filaggrine pour le traitement de la polyarthrite rhumatoide
DE1240180T1 (de) * 1999-12-21 2003-08-14 Innogenetics N.V., Gent Peptide zur diagnose und behandlung rheumatischer arthritis
FR2826124B1 (fr) 2001-06-13 2004-01-02 Bio Merieux Procede de detection d'auto-anticorps specifiques de la polyarthrite rhumatoide
NL1019540C2 (nl) * 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.
CN1809753B (zh) * 2003-07-29 2010-10-20 索尔瓦药物有限公司 通过二维凝胶电泳分析包含生理可接受消化酶混合物的方法
AT413768B (de) * 2003-07-29 2006-05-15 Herkner Kurt Dipl Ing Dr Techn Biochemisches diagnostikum zur erkennung rheumatoider arthritis
WO2005064307A2 (fr) * 2003-12-23 2005-07-14 Roche Diagnostics Gmbh Methode de diagnostic de la polyarthrite rhumatoide, consistant a mesurer la concentration d'anti-ccp et d'interleukine 6
ES2314621T3 (es) 2004-02-27 2009-03-16 F. Hoffmann-La Roche Ag Procedimiento de evaluacion de la artritis reumotoidea, mediante la medicion de anti-ccp y amiloide a serico.
PL2278002T3 (pl) 2005-07-29 2017-12-29 Abbott Laboratories Gmbh Pankreatyna o zmniejszonej zawartości wirusowej
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
GB0525492D0 (en) * 2005-12-15 2006-01-25 Univ Dundee Filaggrin
FR2900657B1 (fr) * 2006-05-03 2009-04-17 Univ Toulouse Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
WO2008037420A1 (fr) 2006-09-29 2008-04-03 Roche Diagnostics Gmbh Évaluation du risque de progression de la maladie pour un patient présentant une polyarthrite rhumatoïde
ES2390394T3 (es) 2007-12-03 2012-11-12 Sqi Diagnostics Systems Inc. Péptidos sintéticos inmunorreactivos con los autoanticuerpos de la artritis reumatoide
EP2294086B1 (fr) 2008-06-04 2017-09-13 ModiQuest B.V. Agents anti-inflammatoires
CA2757444A1 (fr) * 2009-03-30 2010-10-14 Prometheus Laboratories Inc. Peptides citrullines pour diagnostiquer et pronostiquer une polyarthrite rhumatoide
EP2325195A1 (fr) 2009-11-23 2011-05-25 Toscana Biomarkers S.r.l. Peptides à citrulline et utilisations associées
EP2336769A1 (fr) 2009-12-18 2011-06-22 F. Hoffmann-La Roche AG Test pour différencier les troubles rhumatismaux des troubles non rhumatismaux
EP2402368A1 (fr) 2010-07-02 2012-01-04 Toscana Biomarkers S.r.l. Peptides de citrulline histone et utilisations associées
EP2527841A1 (fr) 2011-05-25 2012-11-28 Toscana Biomarkers S.r.l. Procédés pour le diagnostic de l'arthrite rhumatoïde
WO2012163768A1 (fr) * 2011-05-27 2012-12-06 Nordic Bioscience A/S Détection de peptides diagnostiques
US9322822B2 (en) * 2011-08-12 2016-04-26 Hiroshima University Method for detecting asbestos
BR112014014767A2 (pt) 2011-12-16 2017-06-13 Olema Pharmaceuticals Inc novos compostos de benzopirano, composições e usos dos mesmos
WO2014141244A1 (fr) * 2013-03-12 2014-09-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Peptides destinés au traitement de maladies autoimmunes
WO2015010791A2 (fr) 2013-07-24 2015-01-29 Klareskog, Lars Nouveaux anticorps pour le diagnostic et le traitement de la polyarthrite rhumatoïde
KR101634958B1 (ko) * 2014-06-13 2016-06-30 한국생명공학연구원 필라그린 유전자 돌연변이 검출용 프로브, 키트 및 방법
EP3056903A1 (fr) 2015-02-13 2016-08-17 F. Hoffmann-La Roche AG Procédé d'évaluation de l'arthrite rhumatoïde par la mesure de l'anti-CCP et de l'anti-Casp8
WO2016128348A1 (fr) 2015-02-13 2016-08-18 F. Hoffmann-La Roche Ag Procédé d'évaluation de la polyarthrite rhumatoïde par mesure des anti-ccp et anti-pik3cd
EP3056904A1 (fr) 2015-02-13 2016-08-17 F. Hoffmann-La Roche AG Procédé pour l'évaluation de l'arthrite rhumatoïde par la mesure de l'anti-CCP et de l'anti-MCM3
CN111007262A (zh) * 2019-12-25 2020-04-14 漳州卫生职业学院 一种用于辅助诊断ra的试剂盒及检测方法
CN122063281B (zh) * 2026-04-20 2026-06-30 苏州大学 一种用于诊断类风湿性关节炎的生物标志物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660994A (en) * 1986-11-10 1997-08-26 Progen Biotechnik Gmbh Method of detecting tissue-specific, insoluble cytoskeletal proteins
DE511116T1 (de) * 1991-04-26 1993-04-29 Clonatec S.A., Paris Antigene, die von polyarthritis rheumatoide antikoerpern erkannt werden, ihre herstellung und ihre anwendungen.
FR2752842B1 (fr) * 1996-08-30 1998-11-06 Biomerieux Sa Antigenes derives des filaggrines et leur utilisation pour le diagnostic de la polyarthrite rhumatoide
NL1004539C2 (nl) * 1996-11-15 1998-05-20 Stichting Tech Wetenschapp Peptide afgeleid van een door auto-antilichamen van patiënten met reumatoïde artritis herkend antigeen, antilichaam daartegen en werkwijze voor het detecteren van auto-immuunantilichamen.

Also Published As

Publication number Publication date
CZ20001963A3 (cs) 2002-04-17
PL344534A1 (en) 2001-11-05
WO1999028344A2 (fr) 1999-06-10
JP2002512939A (ja) 2002-05-08
AU2155899A (en) 1999-06-16
EP1034186A2 (fr) 2000-09-13
CA2309534A1 (fr) 1999-06-10
WO1999028344A3 (fr) 1999-08-12

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