PL344534A1 - Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment - Google Patents

Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment

Info

Publication number
PL344534A1
PL344534A1 PL98344534A PL34453498A PL344534A1 PL 344534 A1 PL344534 A1 PL 344534A1 PL 98344534 A PL98344534 A PL 98344534A PL 34453498 A PL34453498 A PL 34453498A PL 344534 A1 PL344534 A1 PL 344534A1
Authority
PL
Poland
Prior art keywords
diagnosis
tools
recognized
treatment
rheumatoid arthritis
Prior art date
Application number
PL98344534A
Other languages
English (en)
Inventor
Lydie Meheus
Ann Union
Joseph Raymackers
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP98870078A external-priority patent/EP0949270A1/fr
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Publication of PL344534A1 publication Critical patent/PL344534A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL98344534A 1997-11-28 1998-11-30 Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment PL344534A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97870195 1997-11-28
EP98870078A EP0949270A1 (fr) 1998-04-09 1998-04-09 Peptides synthétiques contenant de la citrulline et reconnus par les sérums de patients souffrant d'arthrite rhumatoide utilisés comme outils de diagnostic et de traitement
PCT/EP1998/007714 WO1999028344A2 (fr) 1997-11-28 1998-11-30 Peptides synthetiques contenant une citrulline reconnue par les serums de malades atteints de polyarthrite rhumatoide comme des outils de diagnostic et de traitement

Publications (1)

Publication Number Publication Date
PL344534A1 true PL344534A1 (en) 2001-11-05

Family

ID=26148315

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98344534A PL344534A1 (en) 1997-11-28 1998-11-30 Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment

Country Status (8)

Country Link
EP (1) EP1034186A2 (fr)
JP (1) JP2002512939A (fr)
AU (1) AU2155899A (fr)
CA (1) CA2309534A1 (fr)
CZ (1) CZ20001963A3 (fr)
HU (1) HUP0004338A2 (fr)
PL (1) PL344534A1 (fr)
WO (1) WO1999028344A2 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7184426B2 (en) 2002-12-12 2007-02-27 Qualcomm, Incorporated Method and apparatus for burst pilot for a time division multiplex system
FR2773078B1 (fr) * 1997-12-30 2000-05-26 Univ Toulouse Utilisation de peptides citrullines derives de la filaggrine pour le traitement de la polyarthrite rhumatoide
EP1240180A2 (fr) * 1999-12-21 2002-09-18 Innogenetics N.V. Peptides permettant de diagnostiquer et de traiter la polyarthrite rhumatoide
FR2826124B1 (fr) 2001-06-13 2004-01-02 Bio Merieux Procede de detection d'auto-anticorps specifiques de la polyarthrite rhumatoide
NL1019540C2 (nl) * 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.
RU2359270C2 (ru) 2003-07-29 2009-06-20 Зольвай Фармасьютиклз Гмбх Способ анализа панкреатита и содержащих его композиций
AT413768B (de) * 2003-07-29 2006-05-15 Herkner Kurt Dipl Ing Dr Techn Biochemisches diagnostikum zur erkennung rheumatoider arthritis
PT1882946E (pt) * 2003-12-23 2010-04-21 Roche Diagnostics Gmbh Método para avaliar artrite reumatóide através da medição de anti-ccp e interleucina 6
EP1721162B1 (fr) 2004-02-27 2008-09-24 Roche Diagnostics GmbH Methode d'evaluation de la polyarthrite rheumatoide consistant a mesurer la concentration d'anti-ccp et de serum amyloide a
RU2413532C2 (ru) 2005-07-29 2011-03-10 Зольвай Фармасьютиклз Гмбх Способ получения стерилизованного порошкообразного панкреатина
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
GB0525492D0 (en) * 2005-12-15 2006-01-25 Univ Dundee Filaggrin
FR2900657B1 (fr) * 2006-05-03 2009-04-17 Univ Toulouse Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
JP2010506147A (ja) 2006-09-29 2010-02-25 エフ．ホフマン−ラ ロシュ アーゲー 関節リウマチを有する患者のための疾患進行のリスク評価
AU2008331381B2 (en) * 2007-12-03 2013-08-22 Sqi Diagnostics Systems Inc. Synthetic peptides immuno-reactive with rheumatoid arthritis auto-antibodies
DK2294086T3 (en) * 2008-06-04 2018-01-02 Modiquest B V ANTI-INFLAMMATORY AGENTS
WO2010117694A2 (fr) * 2009-03-30 2010-10-14 Prometheus Laboratories Inc. Peptides citrullinés pour diagnostiquer et pronostiquer une polyarthrite rhumatoïde
EP2325195A1 (fr) 2009-11-23 2011-05-25 Toscana Biomarkers S.r.l. Peptides à citrulline et utilisations associées
EP2336769A1 (fr) 2009-12-18 2011-06-22 F. Hoffmann-La Roche AG Test pour différencier les troubles rhumatismaux des troubles non rhumatismaux
EP2402368A1 (fr) 2010-07-02 2012-01-04 Toscana Biomarkers S.r.l. Peptides de citrulline histone et utilisations associées
EP2527841A1 (fr) 2011-05-25 2012-11-28 Toscana Biomarkers S.r.l. Procédés pour le diagnostic de l'arthrite rhumatoïde
JP6040228B2 (ja) * 2011-05-27 2016-12-07 ノルディック・ビオサイエンス・エー／エスＮｏｒｄｉｃ Ｂｉｏｓｃｉｅｎｃｅ Ａ／Ｓ 診断用ペプチドの検出
US9322822B2 (en) * 2011-08-12 2016-04-26 Hiroshima University Method for detecting asbestos
EA201490897A1 (ru) 2011-12-16 2015-03-31 Олема Фармасьютикалс, Инк. Новые бензопирановые соединения, композиции и их применение
US9975944B2 (en) * 2013-03-12 2018-05-22 Tel Hashomer Medical Research Infrastructure And Services Ltd. Synthetic peptides for the treatment of autoimmune diseases
US20160159922A1 (en) 2013-07-24 2016-06-09 Vilara Ab Novel Antibodies for the Diagnosis and Treatment of Rheumatoid Arthritis
KR101634958B1 (ko) * 2014-06-13 2016-06-30 한국생명공학연구원 필라그린 유전자 돌연변이 검출용 프로브, 키트 및 방법
EP3056904A1 (fr) 2015-02-13 2016-08-17 F. Hoffmann-La Roche AG Procédé pour l'évaluation de l'arthrite rhumatoïde par la mesure de l'anti-CCP et de l'anti-MCM3
EP3056903A1 (fr) 2015-02-13 2016-08-17 F. Hoffmann-La Roche AG Procédé d'évaluation de l'arthrite rhumatoïde par la mesure de l'anti-CCP et de l'anti-Casp8
CN107484423A (zh) 2015-02-13 2017-12-15 豪夫迈·罗氏有限公司 通过测量抗ccp和抗pik3cd来评估类风湿性关节炎的方法
CN111007262A (zh) * 2019-12-25 2020-04-14 漳州卫生职业学院 一种用于辅助诊断ra的试剂盒及检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660994A (en) * 1986-11-10 1997-08-26 Progen Biotechnik Gmbh Method of detecting tissue-specific, insoluble cytoskeletal proteins
WO1992019649A1 (fr) * 1991-04-26 1992-11-12 Clonatec Antigenes reconnus par des anticorps de la polyarthrite rhumatoide, leur preparation et leurs applications
FR2752842B1 (fr) * 1996-08-30 1998-11-06 Biomerieux Sa Antigenes derives des filaggrines et leur utilisation pour le diagnostic de la polyarthrite rhumatoide
NL1004539C2 (nl) * 1996-11-15 1998-05-20 Stichting Tech Wetenschapp Peptide afgeleid van een door auto-antilichamen van patiënten met reumatoïde artritis herkend antigeen, antilichaam daartegen en werkwijze voor het detecteren van auto-immuunantilichamen.

Also Published As

Publication number Publication date
CA2309534A1 (fr) 1999-06-10
CZ20001963A3 (cs) 2002-04-17
EP1034186A2 (fr) 2000-09-13
JP2002512939A (ja) 2002-05-08
WO1999028344A2 (fr) 1999-06-10
AU2155899A (en) 1999-06-16
WO1999028344A3 (fr) 1999-08-12
HUP0004338A2 (hu) 2001-02-28

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