HUT66570A - (-) and (+) 10-(1-azabicyclo[2,2,2]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for producing them - Google Patents

(-) and (+) 10-(1-azabicyclo[2,2,2]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for producing them Download PDF

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Publication number
HUT66570A
HUT66570A HU9400273A HU9400273A HUT66570A HU T66570 A HUT66570 A HU T66570A HU 9400273 A HU9400273 A HU 9400273A HU 9400273 A HU9400273 A HU 9400273A HU T66570 A HUT66570 A HU T66570A
Authority
HU
Hungary
Prior art keywords
methyl
formula
phenothiazine
oct
quaternary ammonium
Prior art date
Application number
HU9400273A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9400273D0 (en
Inventor
Luigi Turbanti
Raffaello Giorgi
Alessandro Subissi
Original Assignee
Guidotti & C Spa Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guidotti & C Spa Labor filed Critical Guidotti & C Spa Labor
Publication of HU9400273D0 publication Critical patent/HU9400273D0/hu
Publication of HUT66570A publication Critical patent/HUT66570A/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU9400273A 1991-08-07 1992-08-03 (-) and (+) 10-(1-azabicyclo[2,2,2]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for producing them HUT66570A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912225A IT1251161B (it) 1991-08-07 1991-08-07 Derivati ammonio quaternari di (-) e (+)-3-(10 h-fenotiazin-10-ilmetil)-l-azabiciclo (2.2.2.)ottano e composizioni farmaceutiche che li contengono

Publications (2)

Publication Number Publication Date
HU9400273D0 HU9400273D0 (en) 1994-05-30
HUT66570A true HUT66570A (en) 1994-12-28

Family

ID=11360550

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9400273A HUT66570A (en) 1991-08-07 1992-08-03 (-) and (+) 10-(1-azabicyclo[2,2,2]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for producing them

Country Status (19)

Country Link
EP (1) EP0599896A1 (fr)
JP (1) JPH06509570A (fr)
CN (1) CN1071667A (fr)
AU (1) AU2417392A (fr)
BG (1) BG98439A (fr)
BR (1) BR9206339A (fr)
CA (1) CA2114844A1 (fr)
CZ (1) CZ24894A3 (fr)
EC (1) ECSP920859A (fr)
FI (1) FI940530A7 (fr)
HU (1) HUT66570A (fr)
IT (1) IT1251161B (fr)
MA (1) MA22611A1 (fr)
MX (1) MX9204539A (fr)
PT (1) PT100765A (fr)
SK (1) SK11594A3 (fr)
TN (1) TNSN92073A1 (fr)
WO (1) WO1993003029A1 (fr)
ZA (1) ZA925852B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6072113A (en) * 1996-10-18 2000-06-06 Yamaha Corporation Musical performance teaching system and method, and machine readable medium containing program therefor
WO2003105811A2 (fr) * 2002-01-31 2003-12-24 Southwest Research Institute Compositions a liberation progressive et son procede d'utilisation
FR2910814B1 (fr) * 2006-12-28 2011-06-17 Pf Medicament Utilisation du 10-°(r3)-1-azabicyclo°2.2.2!oct-3-ylmethyl!-10h- phenothiazine pour la preparation d'un medicament exercant une inhibition selective des recepteurs muscariniques m1,2,3
FR2911606B1 (fr) * 2007-01-18 2009-04-17 Pierre Fabre Medicament Sa Nouveau derive de la quinuclidine utile dans la preparation de la mequitazine
FR2924344B1 (fr) * 2007-12-04 2010-04-16 Pf Medicament Utilisation de la mequitazine sous la forme de racemate ou d'enantiomeres pour la preparation d'un medicament destine au traitement ou a la prevention de pathologies impliquant les recepteurs histaminiques h4.
FR2970255B1 (fr) 2011-01-10 2013-09-06 Pf Medicament Vinyl quinuclidine utile en tant qu'intermediaire de synthese dans la preparation de la (r)-mequitazine.
JP7599646B2 (ja) * 2020-10-29 2024-12-16 国立大学法人金沢大学 薬物代謝酵素活性を測定するための放射性フッ素標識画像診断薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522660A1 (fr) * 1982-03-05 1983-09-09 Pharmuka Lab Isomere levogyre de la mequitazine, son procede de preparation et medicaments le contenant
FR2526433B1 (fr) * 1982-05-04 1985-10-18 Pharmuka Lab Isomeres dextrogyres de derives de l'aza-1 bicyclo (2,2,2) octane, leur procede de preparation et medicaments les contenant
IT1173445B (it) * 1984-03-16 1987-06-24 Guidotti & C Spa Labor Agenti ad attivita' antibroncospastica e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
IT1251161B (it) 1995-05-04
CA2114844A1 (fr) 1993-02-18
WO1993003029A1 (fr) 1993-02-18
CZ24894A3 (en) 1994-07-13
FI940530L (fi) 1994-02-04
FI940530A0 (fi) 1994-02-04
ZA925852B (en) 1993-03-05
TNSN92073A1 (fr) 1993-06-08
JPH06509570A (ja) 1994-10-27
MX9204539A (es) 1993-02-01
CN1071667A (zh) 1993-05-05
ITMI912225A0 (it) 1991-08-07
PT100765A (pt) 1993-10-29
EP0599896A1 (fr) 1994-06-08
BR9206339A (pt) 1994-11-08
MA22611A1 (fr) 1993-04-01
BG98439A (bg) 1994-09-30
AU2417392A (en) 1993-03-02
ITMI912225A1 (it) 1993-02-07
SK11594A3 (en) 1994-12-07
ECSP920859A (es) 1993-08-03
FI940530A7 (fi) 1994-02-04
HU9400273D0 (en) 1994-05-30

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Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal