HUT67009A - Truncated forms of the hepatocyte growth factor (hgf) receptor pharmaceutical compositions containing them and process for production of them - Google Patents

Truncated forms of the hepatocyte growth factor (hgf) receptor pharmaceutical compositions containing them and process for production of them

Info

Publication number
HUT67009A
HUT67009A HU9303182A HU9303182A HUT67009A HU T67009 A HUT67009 A HU T67009A HU 9303182 A HU9303182 A HU 9303182A HU 9303182 A HU9303182 A HU 9303182A HU T67009 A HUT67009 A HU T67009A
Authority
HU
Hungary
Prior art keywords
growth factor
hepatocyte growth
hgf
production
pharmaceutical compositions
Prior art date
Application number
HU9303182A
Other languages
English (en)
Other versions
HU9303182D0 (en
Inventor
Paolo Comoglio
Tiziana Crepaldi
Maria Prat
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919110202A external-priority patent/GB9110202D0/en
Priority claimed from GB919124896A external-priority patent/GB9124896D0/en
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of HU9303182D0 publication Critical patent/HU9303182D0/hu
Publication of HUT67009A publication Critical patent/HUT67009A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HU9303182A 1991-05-10 1992-04-30 Truncated forms of the hepatocyte growth factor (hgf) receptor pharmaceutical compositions containing them and process for production of them HUT67009A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919110202A GB9110202D0 (en) 1991-05-10 1991-05-10 Truncated forms of the hepatocyte growth factor(hgf)receptor
GB919124896A GB9124896D0 (en) 1991-11-22 1991-11-22 Truncated forms of the hepatocyte growth factor(hgf)receptor

Publications (2)

Publication Number Publication Date
HU9303182D0 HU9303182D0 (en) 1994-03-28
HUT67009A true HUT67009A (en) 1995-01-30

Family

ID=26298888

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9303182A HUT67009A (en) 1991-05-10 1992-04-30 Truncated forms of the hepatocyte growth factor (hgf) receptor pharmaceutical compositions containing them and process for production of them

Country Status (18)

Country Link
US (1) US5571509A (hu)
EP (2) EP0520158A1 (hu)
JP (1) JP3293823B2 (hu)
AT (1) ATE155525T1 (hu)
AU (1) AU651452B2 (hu)
CA (1) CA2102595C (hu)
DE (1) DE69220940T2 (hu)
DK (1) DK0584125T3 (hu)
ES (1) ES2104914T3 (hu)
FI (1) FI934934A7 (hu)
GR (1) GR3024998T3 (hu)
HU (1) HUT67009A (hu)
IE (1) IE921485A1 (hu)
IL (1) IL101809A0 (hu)
MX (1) MX9202129A (hu)
MY (1) MY108614A (hu)
NZ (1) NZ242645A (hu)
WO (1) WO1992020792A1 (hu)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6344321B1 (en) * 1990-06-11 2002-02-05 Gilead Sciences, Inc. Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
CA2142713A1 (en) * 1993-06-30 1995-01-12 Paolo Comoglio Peptide inhibitors of mitogenesis and motogenesis
US5464815A (en) * 1993-09-08 1995-11-07 Genentech, Inc. Inhibition of heparin-binding
US5646036A (en) * 1995-06-02 1997-07-08 Genentech, Inc. Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
WO1997009997A1 (en) * 1995-09-12 1997-03-20 Genentech, Inc. Cystic fibrosis therapy
WO1997012629A1 (en) * 1995-10-05 1997-04-10 Genentech, Inc. Improved angiogenesis using hepatocyte growth factor
WO1997012628A1 (en) * 1995-10-05 1997-04-10 Genentech, Inc. Methods and compositions for treating vascular stenosis
JP2000515735A (ja) * 1996-07-03 2000-11-28 ジェネンテック インコーポレーテッド 肝細胞成長因子レセプターアゴニスト
US5874306A (en) * 1996-12-12 1999-02-23 The Regents Of The University Of California Culturing human pancreatic endocrine cells in medium containing extracellular matrix from human bladder carcinoma cells
US6759206B1 (en) 1997-02-27 2004-07-06 Cellomics, Inc. System for cell-based screening
US6031155A (en) * 1997-06-05 2000-02-29 Cameron-Mills; Verena Arabinoxylan degradation
US20030118585A1 (en) 2001-10-17 2003-06-26 Agy Therapeutics Use of protein biomolecular targets in the treatment and visualization of brain tumors
AU2760602A (en) * 2001-03-23 2002-09-26 Agouron Pharmaceuticals, Inc. Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase, and materials and methods for identification of inhibitors thereof
US7678769B2 (en) * 2001-09-14 2010-03-16 Compugen, Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
US20100183573A1 (en) * 2001-09-14 2010-07-22 Compugen Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
US20040248157A1 (en) * 2001-09-14 2004-12-09 Michal Ayalon-Soffer Novel polynucleotides encoding soluble polypeptides and methods using same
ITMI20031127A1 (it) * 2003-06-05 2004-12-06 Uni Degli Studi Del Piemont E Orientale Am Anticorpi anti-hgf-r e loro uso
EP2093570A1 (en) * 2003-06-06 2009-08-26 Genentech, Inc. Modulating the interaction between HGF beta chain and c-met
WO2005058965A1 (en) * 2003-12-11 2005-06-30 Genentech, Inc. Methods and compositions for inhibiting c-met dimerization and activation
US20060147946A1 (en) * 2004-01-27 2006-07-06 Pinchas Akiva Novel calcium channel variants and methods of use thereof
WO2005071059A2 (en) * 2004-01-27 2005-08-04 Compugen Ltd. Methods of identifying putative gene products by interspecies sequence comparison and biomolecular sequences uncovered thereby
PT1773885E (pt) 2004-08-05 2010-07-21 Genentech Inc Antagonistas anti-cmet humanizados
ZA200710599B (en) 2005-04-15 2009-08-26 Genentech Inc HGF Beta chain variants
CA2624535A1 (en) * 2005-09-30 2007-04-05 Compugen Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
CL2007000851A1 (es) 2006-03-30 2008-03-14 Novartis Ag Anticuerpo anti receptor del factor de crecimiento del hepatocito (c-met); adn que codifican cadenas livianas y pesadas del anticuerpo; composicion farmaceutica y kit que comprenden dicho anticuerpo; metodo para tratar trastorno relacionado con c-met
AU2009208607B2 (en) * 2008-01-31 2013-08-01 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
IL198545A0 (en) * 2008-05-14 2011-07-31 Metheresis Translational Res Sa High affinity binding site of hgfr and methods for identification of antagonists thereof
PA8849001A1 (es) 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
KR101671378B1 (ko) * 2009-10-30 2016-11-01 삼성전자 주식회사 ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그의 용도
JP2013532627A (ja) 2010-07-01 2013-08-19 武田薬品工業株式会社 ｃＭＥＴ阻害剤とＨＧＦおよび／またはｃＭＥＴに対する抗体との組み合わせ
WO2013003680A1 (en) 2011-06-30 2013-01-03 Genentech, Inc. Anti-c-met antibody formulations
US9201074B2 (en) 2011-09-20 2015-12-01 Eli Lilly And Company Anti-c-Met antibodies
MX2016012285A (es) 2014-03-24 2017-01-23 Genentech Inc Tratamiento de cáncer con antagonista de c-met y correlación de estos con la expresión de hgf.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648273A (en) * 1989-12-27 1997-07-15 The United States Of America, As Represented By The Department Of Health And Human Services Hepatic growth factor receptor is the MET proto-oncogene
AU639532B2 (en) * 1989-12-27 1993-07-29 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Diagnostic probe for detecting human stomach cancer

Also Published As

Publication number Publication date
US5571509A (en) 1996-11-05
IL101809A0 (en) 1992-12-30
GR3024998T3 (en) 1998-01-30
JP3293823B2 (ja) 2002-06-17
HU9303182D0 (en) 1994-03-28
IE921485A1 (en) 1992-11-18
EP0520158A1 (en) 1992-12-30
DE69220940D1 (de) 1997-08-21
EP0584125A1 (en) 1994-03-02
CA2102595C (en) 2003-01-14
WO1992020792A1 (en) 1992-11-26
MX9202129A (es) 1992-11-01
FI934934L (fi) 1994-01-05
AU1672092A (en) 1992-12-30
AU651452B2 (en) 1994-07-21
FI934934A0 (fi) 1993-11-08
FI934934A7 (fi) 1994-01-05
DK0584125T3 (da) 1997-09-08
JPH06508508A (ja) 1994-09-29
CA2102595A1 (en) 1992-11-11
ES2104914T3 (es) 1997-10-16
DE69220940T2 (de) 1998-01-15
ATE155525T1 (de) 1997-08-15
NZ242645A (en) 1994-11-25
MY108614A (en) 1996-10-31
EP0584125B1 (en) 1997-07-16

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Legal Events

Date Code Title Description
DFA9 Temporary protection cancelled due to abandonment