HUT68374A - Silage additive - Google Patents

Silage additive Download PDF

Info

Publication number: HUT68374A
Authority: HU; Hungary
Prior art keywords: silage; inhibitor; additive; process according; protease
Prior art date: 1990-08-31

Application number

HU9300450A

Other languages

English (en)

Hungarian (hu)

Other versions

HU9300450D0 (en

Inventor

Jane Ann Wetherall

John Andrew Rooke

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-31

Filing date

1991-08-27

Publication date

1995-06-28

1991-08-27 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1993-05-28 Publication of HU9300450D0 publication Critical patent/HU9300450D0/hu

1995-06-28 Publication of HUT68374A publication Critical patent/HUT68374A/hu

Links

239000004460 silage Substances 0.000 title claims description 75
239000000654 additive Substances 0.000 title claims description 40
230000000996 additive effect Effects 0.000 title claims description 23
239000000137 peptide hydrolase inhibitor Substances 0.000 claims description 22
238000000034 method Methods 0.000 claims description 19
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical group CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 14
229940124158 Protease/peptidase inhibitor Drugs 0.000 claims description 13
230000008569 process Effects 0.000 claims description 13
239000003112 inhibitor Substances 0.000 claims description 12
108091005804 Peptidases Proteins 0.000 claims description 11
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
239000003795 chemical substances by application Substances 0.000 claims description 10
239000004365 Protease Substances 0.000 claims description 8
239000003696 aspartic proteinase inhibitor Substances 0.000 claims description 8
230000001580 bacterial effect Effects 0.000 claims description 8
239000007788 liquid Substances 0.000 claims description 8
235000018417 cysteine Nutrition 0.000 claims description 7
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims description 7
239000002532 enzyme inhibitor Substances 0.000 claims description 7
229940125532 enzyme inhibitor Drugs 0.000 claims description 7
238000000855 fermentation Methods 0.000 claims description 7
230000004151 fermentation Effects 0.000 claims description 7
239000004310 lactic acid Substances 0.000 claims description 7
235000014655 lactic acid Nutrition 0.000 claims description 7
229940092160 Aspartic protease inhibitor Drugs 0.000 claims description 6
OVIFHFRAOKPVPC-UHFFFAOYSA-N aspartic protease inhibitor Natural products CC(N)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(O)=O)C(=O)NC(CC(O)=O)C(=O)NC(CC(O)=O)C(=O)NC(CC(O)=O)C(=O)N1CCCC1C(=O)N1C(C(=O)NC(CCC(O)=O)C(O)=O)CCC1 OVIFHFRAOKPVPC-UHFFFAOYSA-N 0.000 claims description 6
239000002253 acid Substances 0.000 claims description 5
108090000765 processed proteins & peptides Proteins 0.000 claims description 5
102000035101 Aspartic proteases Human genes 0.000 claims description 4
108091005502 Aspartic proteases Proteins 0.000 claims description 4
229940094664 Cysteine protease inhibitor Drugs 0.000 claims description 4
239000004480 active ingredient Substances 0.000 claims description 4
101000749287 Clitocybe nebularis Clitocypin Proteins 0.000 claims description 3
101000767029 Clitocybe nebularis Clitocypin-1 Proteins 0.000 claims description 3
241000209504 Poaceae Species 0.000 claims description 3
235000013339 cereals Nutrition 0.000 claims description 3
235000021374 legumes Nutrition 0.000 claims description 3
108010087765 Antipain Proteins 0.000 claims description 2
102000015833 Cystatin Human genes 0.000 claims description 2
SDNYTAYICBFYFH-TUFLPTIASA-N antipain Chemical compound NC(N)=NCCC[C@@H](C=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 SDNYTAYICBFYFH-TUFLPTIASA-N 0.000 claims description 2
108050004038 cystatin Proteins 0.000 claims description 2
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 2
150000002118 epoxides Chemical class 0.000 claims 2
CGWBIHLHAGNJCX-UHFFFAOYSA-N 2-butylguanidine Chemical compound CCCCNC(N)=N CGWBIHLHAGNJCX-UHFFFAOYSA-N 0.000 claims 1
CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
241001494496 Leersia Species 0.000 claims 1
240000007594 Oryza sativa Species 0.000 claims 1
235000007164 Oryza sativa Nutrition 0.000 claims 1
239000002111 antiemetic agent Substances 0.000 claims 1
229940125683 antiemetic agent Drugs 0.000 claims 1
235000003704 aspartic acid Nutrition 0.000 claims 1
OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 1
235000009566 rice Nutrition 0.000 claims 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 46
241000196324 Embryophyta Species 0.000 description 34
229910052757 nitrogen Inorganic materials 0.000 description 23
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 20
238000011282 treatment Methods 0.000 description 17
229950000964 pepstatin Drugs 0.000 description 16
108010091212 pepstatin Proteins 0.000 description 16
FAXGPCHRFPCXOO-LXTPJMTPSA-N pepstatin A Chemical compound OC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C FAXGPCHRFPCXOO-LXTPJMTPSA-N 0.000 description 16
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 12
239000000203 mixture Substances 0.000 description 12
230000000694 effects Effects 0.000 description 11
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 10
102000035195 Peptidases Human genes 0.000 description 9
229940042399 direct acting antivirals protease inhibitors Drugs 0.000 description 9
235000018102 proteins Nutrition 0.000 description 9
102000004169 proteins and genes Human genes 0.000 description 9
108090000623 proteins and genes Proteins 0.000 description 9
239000007787 solid Substances 0.000 description 9
BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 8
239000000126 substance Substances 0.000 description 8
239000000284 extract Substances 0.000 description 7
229910021529 ammonia Inorganic materials 0.000 description 6
239000000463 material Substances 0.000 description 6
230000017854 proteolysis Effects 0.000 description 6
QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 5
OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 4
241000894006 Bacteria Species 0.000 description 4
150000001720 carbohydrates Chemical class 0.000 description 4
235000014633 carbohydrates Nutrition 0.000 description 4
235000019253 formic acid Nutrition 0.000 description 4
230000005764 inhibitory process Effects 0.000 description 4
230000001737 promoting effect Effects 0.000 description 4
102000005927 Cysteine Proteases Human genes 0.000 description 3
108010005843 Cysteine Proteases Proteins 0.000 description 3
244000061456 Solanum tuberosum Species 0.000 description 3
235000002595 Solanum tuberosum Nutrition 0.000 description 3
240000008042 Zea mays Species 0.000 description 3
235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 3
235000002017 Zea mays subsp mays Nutrition 0.000 description 3
235000001014 amino acid Nutrition 0.000 description 3
150000001413 amino acids Chemical class 0.000 description 3
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
235000005822 corn Nutrition 0.000 description 3
230000007423 decrease Effects 0.000 description 3
230000000813 microbial effect Effects 0.000 description 3
235000015097 nutrients Nutrition 0.000 description 3
239000001301 oxygen Substances 0.000 description 3
229910052760 oxygen Inorganic materials 0.000 description 3
230000002829 reductive effect Effects 0.000 description 3
102000004190 Enzymes Human genes 0.000 description 2
108090000790 Enzymes Proteins 0.000 description 2
240000005979 Hordeum vulgare Species 0.000 description 2
235000007340 Hordeum vulgare Nutrition 0.000 description 2
JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 2
108010064851 Plant Proteins Proteins 0.000 description 2
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
230000002411 adverse Effects 0.000 description 2
XKMRRTOUMJRJIA-UHFFFAOYSA-N ammonia nh3 Chemical compound N.N XKMRRTOUMJRJIA-UHFFFAOYSA-N 0.000 description 2
239000003242 anti bacterial agent Substances 0.000 description 2
229940088710 antibiotic agent Drugs 0.000 description 2
230000008859 change Effects 0.000 description 2
230000003247 decreasing effect Effects 0.000 description 2
230000002255 enzymatic effect Effects 0.000 description 2
229940088598 enzyme Drugs 0.000 description 2
238000002474 experimental method Methods 0.000 description 2
238000009472 formulation Methods 0.000 description 2
230000000670 limiting effect Effects 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 2
YBYRMVIVWMBXKQ-UHFFFAOYSA-N phenylmethanesulfonyl fluoride Chemical compound FS(=O)(=O)CC1=CC=CC=C1 YBYRMVIVWMBXKQ-UHFFFAOYSA-N 0.000 description 2
235000021118 plant-derived protein Nutrition 0.000 description 2
102000004196 processed proteins & peptides Human genes 0.000 description 2
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
230000009467 reduction Effects 0.000 description 2
239000000243 solution Substances 0.000 description 2
YUHQONKVKQCZRU-UHFFFAOYSA-N 1-phenylethanesulfonyl fluoride Chemical compound FS(=O)(=O)C(C)C1=CC=CC=C1 YUHQONKVKQCZRU-UHFFFAOYSA-N 0.000 description 1
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
108700028369 Alleles Proteins 0.000 description 1
GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
108010039627 Aprotinin Proteins 0.000 description 1
208000035404 Autolysis Diseases 0.000 description 1
206010057248 Cell death Diseases 0.000 description 1
235000019733 Fish meal Nutrition 0.000 description 1
241000186660 Lactobacillus Species 0.000 description 1
240000001929 Lactobacillus brevis Species 0.000 description 1
235000013957 Lactobacillus brevis Nutrition 0.000 description 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
235000019738 Limestone Nutrition 0.000 description 1
240000004658 Medicago sativa Species 0.000 description 1
235000017587 Medicago sativa ssp. sativa Nutrition 0.000 description 1
241000237502 Ostreidae Species 0.000 description 1
240000004713 Pisum sativum Species 0.000 description 1
235000010582 Pisum sativum Nutrition 0.000 description 1
DYAHQFWOVKZOOW-UHFFFAOYSA-N Sarin Chemical compound CC(C)OP(C)(F)=O DYAHQFWOVKZOOW-UHFFFAOYSA-N 0.000 description 1
240000006394 Sorghum bicolor Species 0.000 description 1
235000011684 Sorghum saccharatum Nutrition 0.000 description 1
229910000831 Steel Inorganic materials 0.000 description 1
229930006000 Sucrose Natural products 0.000 description 1
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
244000269722 Thea sinensis Species 0.000 description 1
241000219793 Trifolium Species 0.000 description 1
235000021307 Triticum Nutrition 0.000 description 1
244000098338 Triticum aestivum Species 0.000 description 1
238000010306 acid treatment Methods 0.000 description 1
150000001336 alkenes Chemical class 0.000 description 1
BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
229910052921 ammonium sulfate Inorganic materials 0.000 description 1
235000011130 ammonium sulphate Nutrition 0.000 description 1
239000003963 antioxidant agent Substances 0.000 description 1
229960004405 aprotinin Drugs 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
239000007900 aqueous suspension Substances 0.000 description 1
239000001273 butane Substances 0.000 description 1
229940041514 candida albicans extract Drugs 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
-1 chalk Substances 0.000 description 1
239000004927 clay Substances 0.000 description 1
239000013068 control sample Substances 0.000 description 1
244000038559 crop plants Species 0.000 description 1
208000031513 cyst Diseases 0.000 description 1
239000002852 cysteine proteinase inhibitor Substances 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
238000001035 drying Methods 0.000 description 1
239000000428 dust Substances 0.000 description 1
ULFUJLFTRWWLPO-UHFFFAOYSA-N ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate Chemical compound CCOC(=O)C1=C(C)NC(CC(C)(C)CC2=O)=C2C1C(C=C1)=CC=C1C1=CC=CC=C1 ULFUJLFTRWWLPO-UHFFFAOYSA-N 0.000 description 1
239000004467 fishmeal Substances 0.000 description 1
239000003102 growth factor Substances 0.000 description 1
125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
238000011534 incubation Methods 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 description 1
JDNTWHVOXJZDSN-UHFFFAOYSA-N iodoacetic acid Chemical compound OC(=O)CI JDNTWHVOXJZDSN-UHFFFAOYSA-N 0.000 description 1
238000004255 ion exchange chromatography Methods 0.000 description 1
235000015094 jam Nutrition 0.000 description 1
229940039696 lactobacillus Drugs 0.000 description 1
239000008101 lactose Substances 0.000 description 1
239000006028 limestone Substances 0.000 description 1
239000012669 liquid formulation Substances 0.000 description 1
239000001095 magnesium carbonate Substances 0.000 description 1
ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
229910000021 magnesium carbonate Inorganic materials 0.000 description 1
235000014380 magnesium carbonate Nutrition 0.000 description 1
235000012054 meals Nutrition 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
244000005700 microbiome Species 0.000 description 1
235000013336 milk Nutrition 0.000 description 1
239000008267 milk Substances 0.000 description 1
210000004080 milk Anatomy 0.000 description 1
IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 description 1
OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 1
229910017464 nitrogen compound Inorganic materials 0.000 description 1
150000002830 nitrogen compounds Chemical class 0.000 description 1
235000016709 nutrition Nutrition 0.000 description 1
239000003921 oil Substances 0.000 description 1
JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
150000002924 oxiranes Chemical class 0.000 description 1
235000020636 oyster Nutrition 0.000 description 1
210000003819 peripheral blood mononuclear cell Anatomy 0.000 description 1
PIJVFDBKTWXHHD-HIFRSBDPSA-N physostigmine Chemical compound C12=CC(OC(=O)NC)=CC=C2N(C)[C@@H]2[C@@]1(C)CCN2C PIJVFDBKTWXHHD-HIFRSBDPSA-N 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
238000001243 protein synthesis Methods 0.000 description 1
230000002797 proteolythic effect Effects 0.000 description 1
229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 1
238000000746 purification Methods 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
210000004767 rumen Anatomy 0.000 description 1
230000028043 self proteolysis Effects 0.000 description 1
210000002966 serum Anatomy 0.000 description 1
238000006884 silylation reaction Methods 0.000 description 1
239000008247 solid mixture Substances 0.000 description 1
241000894007 species Species 0.000 description 1
239000010959 steel Substances 0.000 description 1
210000002784 stomach Anatomy 0.000 description 1
239000000758 substrate Substances 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
235000000346 sugar Nutrition 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
230000014616 translation Effects 0.000 description 1
230000035899 viability Effects 0.000 description 1
230000000007 visual effect Effects 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
239000012138 yeast extract Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
- A23K30/10—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder
- A23K30/15—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging
- A23K30/18—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging using microorganisms or enzymes
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
- A23K30/10—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder
- A23K30/15—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Polymers & Plastics (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Husbandry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Food Science & Technology (AREA)
Fodder In General (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

HU9300450A 1990-08-31 1991-08-27 Silage additive HUT68374A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909019024A GB9019024D0 (en)	1990-08-31	1990-08-31	Silage additive

Publications (2)

Publication Number	Publication Date
HU9300450D0 HU9300450D0 (en)	1993-05-28
HUT68374A true HUT68374A (en)	1995-06-28

Family

ID=10681446

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU9300450A HUT68374A (en)	1990-08-31	1991-08-27	Silage additive

Country Status (17)

Country	Link
EP (1)	EP0546017A1 (cs)
JP (1)	JPH06500692A (cs)
AU (1)	AU658368B2 (cs)
BG (1)	BG60635B1 (cs)
BR (1)	BR9106792A (cs)
CA (1)	CA2090603A1 (cs)
CZ (1)	CZ27793A3 (cs)
FI (1)	FI930896A7 (cs)
GB (1)	GB9019024D0 (cs)
HU (1)	HUT68374A (cs)
IE (1)	IE64928B1 (cs)
NO (1)	NO930712L (cs)
NZ (1)	NZ239616A (cs)
RO (1)	RO110194B1 (cs)
SK (1)	SK13993A3 (cs)
WO (1)	WO1992003933A1 (cs)
ZA (1)	ZA916923B (cs)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO312081B1 (no) *	1999-10-29	2002-03-18	Noraqua Innovation As	Formulert proteinholdig fôr og anvendelse av slikt fôr

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE701217C (de) *	1938-08-10	1941-01-11	I G Farbenindustrie Akt Ges	Mittel zur Kaltsilage von Gruenfutter
IL73665A0 (en) *	1983-12-09	1985-02-28	Genetic Diagnostic Corp	Promoting animal and plant growth with protease inhibitors
AU4833790A (en) *	1988-12-29	1990-08-01	Eighth Milieu Nominees Pty. Ltd.	Improvements relating to manufacture of rice straw silage

1990
- 1990-08-31 GB GB909019024A patent/GB9019024D0/en active Pending
1991
- 1991-08-27 AU AU84390/91A patent/AU658368B2/en not_active Ceased
- 1991-08-27 BR BR919106792A patent/BR9106792A/pt not_active Application Discontinuation
- 1991-08-27 RO RO93-00266A patent/RO110194B1/ro unknown
- 1991-08-27 JP JP3514798A patent/JPH06500692A/ja active Pending
- 1991-08-27 HU HU9300450A patent/HUT68374A/hu unknown
- 1991-08-27 SK SK13993A patent/SK13993A3/sk unknown
- 1991-08-27 FI FI930896A patent/FI930896A7/fi not_active Application Discontinuation
- 1991-08-27 WO PCT/GB1991/001438 patent/WO1992003933A1/en not_active Ceased
- 1991-08-27 CA CA002090603A patent/CA2090603A1/en not_active Abandoned
- 1991-08-27 EP EP91915519A patent/EP0546017A1/en not_active Ceased
- 1991-08-28 IE IE304191A patent/IE64928B1/en not_active IP Right Cessation
- 1991-08-30 ZA ZA916923A patent/ZA916923B/xx unknown
- 1991-08-30 NZ NZ239616A patent/NZ239616A/en unknown
1993
- 1993-02-25 BG BG97480A patent/BG60635B1/bg unknown
- 1993-02-25 CZ CZ93277A patent/CZ27793A3/cs unknown
- 1993-02-26 NO NO93930712A patent/NO930712L/no unknown

Also Published As

Publication number	Publication date
BG60635B1 (bg)	1995-11-30
ZA916923B (en)	1992-06-24
EP0546017A1 (en)	1993-06-16
BR9106792A (pt)	1993-06-29
AU658368B2 (en)	1995-04-13
GB9019024D0 (en)	1990-10-17
FI930896A0 (fi)	1993-02-26
NZ239616A (en)	1994-02-25
NO930712L (no)	1993-04-26
RO110194B1 (ro)	1995-11-30
SK13993A3 (en)	1993-07-07
JPH06500692A (ja)	1994-01-27
NO930712D0 (no)	1993-02-26
CZ27793A3 (en)	1993-10-13
IE64928B1 (en)	1995-09-20
CA2090603A1 (en)	1992-03-01
BG97480A (bg)	1994-03-24
WO1992003933A1 (en)	1992-03-19
AU8439091A (en)	1992-03-30
HU9300450D0 (en)	1993-05-28
IE913041A1 (en)	1992-03-11
FI930896L (fi)	1993-02-26
FI930896A7 (fi)	1993-02-26

Legal Events

Date	Code	Title	Description
1997-05-28	DFD9	Temporary protection cancelled due to non-payment of fee

Publication	Publication Date	Title
Albrecht et al.	1991	Proteolysis in ensiled forage legumes that vary in tannin concentration
Baytok et al.	2005	The effects of formic acid, molasses and inoculant as silage additives on corn silage composition and ruminal fermentation characteristics in sheep
US6221381B1 (en)	2001-04-24	Enhancing milk production by adding to feed a nonionic surfactant coated on a carrier
Pinthong et al.	1980	The development of a soya‐based yoghurt: I. Acid production by lactic acid bacteria
Kung Jr et al.	1987	Microbial inoculation of low moisture alfalfa silage
MXPA97008793A (en)	1998-02-01	Bacterial treatment for ensil
Wang et al.	2007	Effects of mixing sainfoin with alfalfa on ensiling, ruminal fermentation and total tract digestion of silage
EP1438901A1 (en)	2004-07-21	Silage additive and a process for preparing silage using it
Haigh et al.	1987	Effect of commercial inoculant and formic acid±formalin silage additives on silage fermentation and intake and on liveweight change of young cattle
Stallings et al.	1981	Changes in alfalfa haylage during wilting and ensiling with and without additives
Lorenzo et al.	2008	Alternatives to formic acid as a grass silage additive under two contrasting ensilability conditions
Han et al.	2000	Moisture effect on fermentation characteristics of cup-plant silage
US2940857A (en)	1960-06-14	Preservation of silage
Sotola	1930	OF THE PROTEINS IN ALFALFA HAY AND IN CORN
Mustafa et al.	2003	Effects of stage of maturity on ensiling characteristics and ruminal nutrient degradability of oat silage
Karr et al.	1965	Nutritional and chemical evaluation of urea and of biuret in complete ensiled finishing diets by lambs
US4321278A (en)	1982-03-23	Animal feedstuffs and process
Kung Jr et al.	1989	Ammonia-treated alfalfa silage for lactating dairy cows
Thonney et al.	1980	Microbial and chemical additives in alfalfa-timothy silage
AU658368B2 (en)	1995-04-13	Silage additive
Van Niekerk et al.	2010	Influence of growth stage at harvest on fermentative characteristics of Panicum maximum silage
Kung Jr et al.	1986	Effect of adding formaldehyde, glutaraldehyde, or dimethylolurea to alfalfa before ensiling
Jacobs et al.	1995	Effect of ensiling whole barley grain with pasture on silage quality and effluent production, and the performance of growing cattle
Shockey et al.	1991	Effect of salt on fermentation of alfalfa. 1. Treatment with potassium chloride
JP2839862B2 (ja)	1998-12-16	イソチオシアナートを含有する嗜好性向上用飼料添加組成物及びそれを用いる家畜用飼料の嗜好性向上方法