JPH06500692A - サイレージ添加剤 - Google Patents
サイレージ添加剤Info
- Publication number
- JPH06500692A JPH06500692A JP3514798A JP51479891A JPH06500692A JP H06500692 A JPH06500692 A JP H06500692A JP 3514798 A JP3514798 A JP 3514798A JP 51479891 A JP51479891 A JP 51479891A JP H06500692 A JPH06500692 A JP H06500692A
- Authority
- JP
- Japan
- Prior art keywords
- silage
- inhibitor
- additive
- protease
- cysteine protease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000004460 silage Substances 0.000 title claims description 106
- 239000000654 additive Substances 0.000 title claims description 50
- 230000000996 additive effect Effects 0.000 title claims description 33
- 239000003112 inhibitor Substances 0.000 claims description 32
- 238000000034 method Methods 0.000 claims description 29
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims description 26
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 24
- 108091005804 Peptidases Proteins 0.000 claims description 22
- 239000004480 active ingredient Substances 0.000 claims description 20
- 241000186660 Lactobacillus Species 0.000 claims description 17
- 229940039696 lactobacillus Drugs 0.000 claims description 17
- 102000005927 Cysteine Proteases Human genes 0.000 claims description 16
- 108010005843 Cysteine Proteases Proteins 0.000 claims description 16
- 238000000855 fermentation Methods 0.000 claims description 16
- 101000749287 Clitocybe nebularis Clitocypin Proteins 0.000 claims description 15
- 101000767029 Clitocybe nebularis Clitocypin-1 Proteins 0.000 claims description 15
- 229940094664 Cysteine protease inhibitor Drugs 0.000 claims description 15
- 230000004151 fermentation Effects 0.000 claims description 15
- 101000898643 Candida albicans Vacuolar aspartic protease Proteins 0.000 claims description 14
- 101000898773 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Saccharopepsin Proteins 0.000 claims description 14
- 108010087765 Antipain Proteins 0.000 claims description 13
- 101000898783 Candida tropicalis Candidapepsin Proteins 0.000 claims description 13
- 101000898784 Cryphonectria parasitica Endothiapepsin Proteins 0.000 claims description 13
- 101000933133 Rhizopus niveus Rhizopuspepsin-1 Proteins 0.000 claims description 13
- 101000910082 Rhizopus niveus Rhizopuspepsin-2 Proteins 0.000 claims description 13
- 101000910079 Rhizopus niveus Rhizopuspepsin-3 Proteins 0.000 claims description 13
- 101000910086 Rhizopus niveus Rhizopuspepsin-4 Proteins 0.000 claims description 13
- 101000910088 Rhizopus niveus Rhizopuspepsin-5 Proteins 0.000 claims description 13
- SDNYTAYICBFYFH-TUFLPTIASA-N antipain Chemical compound NC(N)=NCCC[C@@H](C=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 SDNYTAYICBFYFH-TUFLPTIASA-N 0.000 claims description 13
- 230000001580 bacterial effect Effects 0.000 claims description 13
- 238000004519 manufacturing process Methods 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 claims description 12
- 239000002532 enzyme inhibitor Substances 0.000 claims description 12
- 239000004310 lactic acid Substances 0.000 claims description 12
- 235000014655 lactic acid Nutrition 0.000 claims description 12
- 102000015833 Cystatin Human genes 0.000 claims description 11
- 108050004038 cystatin Proteins 0.000 claims description 11
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 claims description 11
- 229940125532 enzyme inhibitor Drugs 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 230000005764 inhibitory process Effects 0.000 claims description 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 8
- 239000003696 aspartic proteinase inhibitor Substances 0.000 claims description 7
- 235000013339 cereals Nutrition 0.000 claims description 7
- 229940092160 Aspartic protease inhibitor Drugs 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 6
- OVIFHFRAOKPVPC-UHFFFAOYSA-N aspartic protease inhibitor Natural products CC(N)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(O)=O)C(=O)NC(CC(O)=O)C(=O)NC(CC(O)=O)C(=O)NC(CC(O)=O)C(=O)N1CCCC1C(=O)N1C(C(=O)NC(CCC(O)=O)C(O)=O)CCC1 OVIFHFRAOKPVPC-UHFFFAOYSA-N 0.000 claims description 6
- CGWBIHLHAGNJCX-UHFFFAOYSA-N 2-butylguanidine Chemical compound CCCCNC(N)=N CGWBIHLHAGNJCX-UHFFFAOYSA-N 0.000 claims description 5
- 240000003483 Leersia hexandra Species 0.000 claims description 4
- 240000007594 Oryza sativa Species 0.000 claims description 4
- 235000007164 Oryza sativa Nutrition 0.000 claims description 4
- 235000021374 legumes Nutrition 0.000 claims description 4
- 235000009566 rice Nutrition 0.000 claims description 4
- 108091005508 Acid proteases Proteins 0.000 claims description 3
- 244000003416 Asparagus officinalis Species 0.000 claims description 3
- 235000005340 Asparagus officinalis Nutrition 0.000 claims description 3
- 108091005502 Aspartic proteases Proteins 0.000 claims description 3
- 102000035101 Aspartic proteases Human genes 0.000 claims description 3
- 241000209504 Poaceae Species 0.000 claims description 3
- 150000002118 epoxides Chemical class 0.000 claims 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
- 108010091212 pepstatin Proteins 0.000 description 39
- FAXGPCHRFPCXOO-LXTPJMTPSA-N pepstatin A Chemical group OC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C FAXGPCHRFPCXOO-LXTPJMTPSA-N 0.000 description 39
- 229950000964 pepstatin Drugs 0.000 description 37
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 36
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 36
- 230000000694 effects Effects 0.000 description 25
- 244000025254 Cannabis sativa Species 0.000 description 23
- 102000035195 Peptidases Human genes 0.000 description 21
- 238000011282 treatment Methods 0.000 description 21
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 18
- 239000004365 Protease Substances 0.000 description 18
- 229910021529 ammonia Inorganic materials 0.000 description 18
- 229910052757 nitrogen Inorganic materials 0.000 description 18
- 239000000203 mixture Substances 0.000 description 16
- 239000000126 substance Substances 0.000 description 16
- 230000002829 reductive effect Effects 0.000 description 15
- 235000019419 proteases Nutrition 0.000 description 13
- 239000002852 cysteine proteinase inhibitor Substances 0.000 description 11
- 241000194017 Streptococcus Species 0.000 description 10
- BDAGIHXWWSANSR-UHFFFAOYSA-N formic acid Substances OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 10
- YBYRMVIVWMBXKQ-UHFFFAOYSA-N phenylmethanesulfonyl fluoride Chemical compound FS(=O)(=O)CC1=CC=CC=C1 YBYRMVIVWMBXKQ-UHFFFAOYSA-N 0.000 description 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 9
- 239000000284 extract Substances 0.000 description 8
- 239000000047 product Substances 0.000 description 8
- 235000018102 proteins Nutrition 0.000 description 8
- 102000004169 proteins and genes Human genes 0.000 description 8
- 108090000623 proteins and genes Proteins 0.000 description 8
- 244000061456 Solanum tuberosum Species 0.000 description 7
- 235000002595 Solanum tuberosum Nutrition 0.000 description 7
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 6
- 241000209082 Lolium Species 0.000 description 6
- 239000013068 control sample Substances 0.000 description 6
- 230000003247 decreasing effect Effects 0.000 description 6
- 230000017854 proteolysis Effects 0.000 description 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 5
- 108090000790 Enzymes Proteins 0.000 description 5
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 5
- 241000194020 Streptococcus thermophilus Species 0.000 description 5
- 229940024606 amino acid Drugs 0.000 description 5
- 235000001014 amino acid Nutrition 0.000 description 5
- 150000001413 amino acids Chemical class 0.000 description 5
- 235000014633 carbohydrates Nutrition 0.000 description 5
- 150000001720 carbohydrates Chemical class 0.000 description 5
- 229940088598 enzyme Drugs 0.000 description 5
- 230000000813 microbial effect Effects 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 241000186714 Lactobacillus amylophilus Species 0.000 description 4
- 244000199866 Lactobacillus casei Species 0.000 description 4
- 235000013958 Lactobacillus casei Nutrition 0.000 description 4
- 101710141454 Nucleoprotein Proteins 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
- 240000008042 Zea mays Species 0.000 description 4
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 4
- 150000007513 acids Chemical class 0.000 description 4
- CKLJMWTZIZZHCS-REOHCLBHSA-N aspartic acid group Chemical group N[C@@H](CC(=O)O)C(=O)O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 4
- 235000005822 corn Nutrition 0.000 description 4
- 235000018417 cysteine Nutrition 0.000 description 4
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 235000019253 formic acid Nutrition 0.000 description 4
- 229940017800 lactobacillus casei Drugs 0.000 description 4
- 102000004196 processed proteins & peptides Human genes 0.000 description 4
- 230000014616 translation Effects 0.000 description 4
- LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 description 3
- 240000005979 Hordeum vulgare Species 0.000 description 3
- 235000007340 Hordeum vulgare Nutrition 0.000 description 3
- 241000192001 Pediococcus Species 0.000 description 3
- 108010064851 Plant Proteins Proteins 0.000 description 3
- 102000012479 Serine Proteases Human genes 0.000 description 3
- 108010022999 Serine Proteases Proteins 0.000 description 3
- 244000057717 Streptococcus lactis Species 0.000 description 3
- 235000014897 Streptococcus lactis Nutrition 0.000 description 3
- 241000209140 Triticum Species 0.000 description 3
- 235000021307 Triticum Nutrition 0.000 description 3
- 229940019748 antifibrinolytic proteinase inhibitors Drugs 0.000 description 3
- 235000003704 aspartic acid Nutrition 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 3
- 229960003067 cystine Drugs 0.000 description 3
- 239000004459 forage Substances 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 235000021118 plant-derived protein Nutrition 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- 240000001046 Lactobacillus acidophilus Species 0.000 description 2
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 2
- 241001134659 Lactobacillus curvatus Species 0.000 description 2
- 240000004296 Lolium perenne Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 240000004713 Pisum sativum Species 0.000 description 2
- 241000208474 Protea Species 0.000 description 2
- 102000018968 Salivary Cystatins Human genes 0.000 description 2
- 108010026774 Salivary Cystatins Proteins 0.000 description 2
- 235000019764 Soybean Meal Nutrition 0.000 description 2
- 241000219793 Trifolium Species 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 238000012870 ammonium sulfate precipitation Methods 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 239000007900 aqueous suspension Substances 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 238000002523 gelfiltration Methods 0.000 description 2
- 238000003306 harvesting Methods 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- JDNTWHVOXJZDSN-UHFFFAOYSA-N iodoacetic acid Chemical compound OC(=O)CI JDNTWHVOXJZDSN-UHFFFAOYSA-N 0.000 description 2
- 238000004255 ion exchange chromatography Methods 0.000 description 2
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 2
- 239000006194 liquid suspension Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 150000002924 oxiranes Chemical class 0.000 description 2
- YFZOUMNUDGGHIW-UHFFFAOYSA-M p-chloromercuribenzoic acid Chemical compound OC(=O)C1=CC=C([Hg]Cl)C=C1 YFZOUMNUDGGHIW-UHFFFAOYSA-M 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- 238000001243 protein synthesis Methods 0.000 description 2
- 210000004767 rumen Anatomy 0.000 description 2
- 239000008247 solid mixture Substances 0.000 description 2
- 239000004455 soybean meal Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- PMHUSCHKTSTQEP-UHFFFAOYSA-N (4-carbamimidoylphenyl)methanesulfonyl fluoride Chemical compound NC(=N)C1=CC=C(CS(F)(=O)=O)C=C1 PMHUSCHKTSTQEP-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- QGZKDVFQNNGYKY-OUBTZVSYSA-N Ammonia-15N Chemical compound [15NH3] QGZKDVFQNNGYKY-OUBTZVSYSA-N 0.000 description 1
- 108010017640 Aspartic Acid Proteases Proteins 0.000 description 1
- 102000004580 Aspartic Acid Proteases Human genes 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- OWNRRUFOJXFKCU-UHFFFAOYSA-N Bromadiolone Chemical compound C=1C=C(C=2C=CC(Br)=CC=2)C=CC=1C(O)CC(C=1C(OC2=CC=CC=C2C=1O)=O)C1=CC=CC=C1 OWNRRUFOJXFKCU-UHFFFAOYSA-N 0.000 description 1
- 241000282994 Cervidae Species 0.000 description 1
- 241000194032 Enterococcus faecalis Species 0.000 description 1
- 101000921786 Homo sapiens Cystatin-A Proteins 0.000 description 1
- 240000001929 Lactobacillus brevis Species 0.000 description 1
- 235000013957 Lactobacillus brevis Nutrition 0.000 description 1
- 240000006024 Lactobacillus plantarum Species 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 235000019738 Limestone Nutrition 0.000 description 1
- 240000004658 Medicago sativa Species 0.000 description 1
- 235000017587 Medicago sativa ssp. sativa Nutrition 0.000 description 1
- 101100075072 Mus musculus Lmtk2 gene Proteins 0.000 description 1
- 101100037618 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) ant-1 gene Proteins 0.000 description 1
- 241001603151 Philus Species 0.000 description 1
- 101710115215 Protease inhibitors Proteins 0.000 description 1
- 229940122055 Serine protease inhibitor Drugs 0.000 description 1
- 101710102218 Serine protease inhibitor Proteins 0.000 description 1
- 240000006394 Sorghum bicolor Species 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- XKMRRTOUMJRJIA-UHFFFAOYSA-N ammonia nh3 Chemical compound N.N XKMRRTOUMJRJIA-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000006286 aqueous extract Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 229940009098 aspartate Drugs 0.000 description 1
- 238000006065 biodegradation reaction Methods 0.000 description 1
- 239000001273 butane Substances 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- -1 chalk Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000004927 clay Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000010410 dusting Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- YMTINGFKWWXKFG-UHFFFAOYSA-N fenofibrate Chemical compound C1=CC(OC(C)(C)C(=O)OC(C)C)=CC=C1C(=O)C1=CC=C(Cl)C=C1 YMTINGFKWWXKFG-UHFFFAOYSA-N 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 102000045247 human CSTA Human genes 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000006028 limestone Substances 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 235000014380 magnesium carbonate Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 description 1
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000003001 serine protease inhibitor Substances 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 210000004885 white matter Anatomy 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
- A23K30/10—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder
- A23K30/15—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging
- A23K30/18—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging using microorganisms or enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
- A23K30/10—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder
- A23K30/15—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9019024.0 | 1990-08-31 | ||
| GB909019024A GB9019024D0 (en) | 1990-08-31 | 1990-08-31 | Silage additive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH06500692A true JPH06500692A (ja) | 1994-01-27 |
Family
ID=10681446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3514798A Pending JPH06500692A (ja) | 1990-08-31 | 1991-08-27 | サイレージ添加剤 |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0546017A1 (cs) |
| JP (1) | JPH06500692A (cs) |
| AU (1) | AU658368B2 (cs) |
| BG (1) | BG60635B1 (cs) |
| BR (1) | BR9106792A (cs) |
| CA (1) | CA2090603A1 (cs) |
| CZ (1) | CZ27793A3 (cs) |
| FI (1) | FI930896A7 (cs) |
| GB (1) | GB9019024D0 (cs) |
| HU (1) | HUT68374A (cs) |
| IE (1) | IE64928B1 (cs) |
| NO (1) | NO930712L (cs) |
| NZ (1) | NZ239616A (cs) |
| RO (1) | RO110194B1 (cs) |
| SK (1) | SK13993A3 (cs) |
| WO (1) | WO1992003933A1 (cs) |
| ZA (1) | ZA916923B (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO312081B1 (no) * | 1999-10-29 | 2002-03-18 | Noraqua Innovation As | Formulert proteinholdig fôr og anvendelse av slikt fôr |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE701217C (de) * | 1938-08-10 | 1941-01-11 | I G Farbenindustrie Akt Ges | Mittel zur Kaltsilage von Gruenfutter |
| IL73665A0 (en) * | 1983-12-09 | 1985-02-28 | Genetic Diagnostic Corp | Promoting animal and plant growth with protease inhibitors |
| AU4833790A (en) * | 1988-12-29 | 1990-08-01 | Eighth Milieu Nominees Pty. Ltd. | Improvements relating to manufacture of rice straw silage |
-
1990
- 1990-08-31 GB GB909019024A patent/GB9019024D0/en active Pending
-
1991
- 1991-08-27 AU AU84390/91A patent/AU658368B2/en not_active Ceased
- 1991-08-27 BR BR919106792A patent/BR9106792A/pt not_active Application Discontinuation
- 1991-08-27 RO RO93-00266A patent/RO110194B1/ro unknown
- 1991-08-27 JP JP3514798A patent/JPH06500692A/ja active Pending
- 1991-08-27 HU HU9300450A patent/HUT68374A/hu unknown
- 1991-08-27 SK SK13993A patent/SK13993A3/sk unknown
- 1991-08-27 FI FI930896A patent/FI930896A7/fi not_active Application Discontinuation
- 1991-08-27 WO PCT/GB1991/001438 patent/WO1992003933A1/en not_active Ceased
- 1991-08-27 CA CA002090603A patent/CA2090603A1/en not_active Abandoned
- 1991-08-27 EP EP91915519A patent/EP0546017A1/en not_active Ceased
- 1991-08-28 IE IE304191A patent/IE64928B1/en not_active IP Right Cessation
- 1991-08-30 ZA ZA916923A patent/ZA916923B/xx unknown
- 1991-08-30 NZ NZ239616A patent/NZ239616A/en unknown
-
1993
- 1993-02-25 BG BG97480A patent/BG60635B1/bg unknown
- 1993-02-25 CZ CZ93277A patent/CZ27793A3/cs unknown
- 1993-02-26 NO NO93930712A patent/NO930712L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG60635B1 (bg) | 1995-11-30 |
| ZA916923B (en) | 1992-06-24 |
| EP0546017A1 (en) | 1993-06-16 |
| BR9106792A (pt) | 1993-06-29 |
| AU658368B2 (en) | 1995-04-13 |
| GB9019024D0 (en) | 1990-10-17 |
| FI930896A0 (fi) | 1993-02-26 |
| NZ239616A (en) | 1994-02-25 |
| NO930712L (no) | 1993-04-26 |
| RO110194B1 (ro) | 1995-11-30 |
| SK13993A3 (en) | 1993-07-07 |
| NO930712D0 (no) | 1993-02-26 |
| CZ27793A3 (en) | 1993-10-13 |
| IE64928B1 (en) | 1995-09-20 |
| CA2090603A1 (en) | 1992-03-01 |
| BG97480A (bg) | 1994-03-24 |
| HUT68374A (en) | 1995-06-28 |
| WO1992003933A1 (en) | 1992-03-19 |
| AU8439091A (en) | 1992-03-30 |
| HU9300450D0 (en) | 1993-05-28 |
| IE913041A1 (en) | 1992-03-11 |
| FI930896L (fi) | 1993-02-26 |
| FI930896A7 (fi) | 1993-02-26 |
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